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Sonichem Launches Project to Transform the Automotive Industry with Bio-Based Plastics

Sonichem

A consortium led by sustainable technology innovator Sonichem has been granted nearly £600,000 in funding from Innovate UK ’s 'Resource efficiency for materials and manufacturing' (REforMM) programme. The funding will accelerate the development of the proprietary Sonichem ultrasound technology and the production of renewable, cost-effective alternatives to petrochemicals commonly used in the production of plastics, resins, and composites within the automotive industry. The cutting-edge CARMA (carbon-neutral agroforestry-derived resins to materials for automotive applications) project will apply Sonichem’s ultrasonic processing technique to automotive applications for the first time. The patented breakthrough approach converts sawdust, the biomass by-product from forestry operations, into high-quality lignin. This renewable material will then serve as the basis for bio-based platform chemicals, creating green alternatives to conventional petrochemical-derived materials currently used to produce various vehicle components. This transformative initiative is being undertaken in collaboration with technology innovation catalyst CPI, the National Composites Centre (NCC), Scott Bader, SHD Composites and Polestar, with each industry leader contributing its own specialised knowledge and expertise. In particular, CPI will support scale-up of the Sonichem technology; Scott Bader will pioneer the development of high-performance, sustainable composite resin formulations; and the NCC, SHD Composites and Polestar will together explore the potential of these novel materials for automotive interiors applications. The CARMA project aligns with the UK Government's focus on resource-efficient, sustainable industrial materials as it aims to significantly reduce the UK’s reliance on imported composite materials, which currently amounts to approximately £250-260 million per year. The newly awarded funding from Innovate UK will enable the international consortium to establish a robust and renewable lignin supply chain within the UK and accelerate the formulation of sustainable plastics and resins that contribute to steering the automotive industry toward a net-zero future and enhancing the UK’s bioeconomy. Adrian Black, CEO of Sonichem, said: “We're extremely pleased to have the backing of Innovate UK's REforMM programme for this strong industrial consortium. This funding is a catalyst in our quest to offer the automotive industry a sustainable alternative to petrochemical-derived plastics. With Sonichem's ultrasound technology and the collaborative expertise of our partners, we are set to make strides toward a net-zero future and strengthen the UK's bioeconomy.” David Fishpool, Verification Manager at the NCC, said: “Creating a sustainable future is at the core of our mission. The National Composites Centre is proud to be part of this transformative initiative to accelerate the development of sustainable, cost-effective alternatives to petrochemicals in the production of plastics, resins, and composites for the automotive industry. Our role in this project underscores our commitment to driving innovation and sustainability in the materials sector. We eagerly anticipate contributing our expertise to this vital effort today, for a greener tomorrow.” Steven Brown, Group Sustainable Technology Manager at Scott Bader, commented: “Scott Bader is pleased to be part of this exciting project, and we look forward to working with our highly regarded industrial and technology partners to accelerate the valorisation of abundant and sustainable biomass towards high-performance materials.” Nick Smith, Technical Director at SHD Composites, said: “SHD Composite Materials Ltd. is very excited to be working with Sonichem on the next generation of sustainable resins wholly sourced from UK feedstocks as part of our ongoing commitment to reduce the ecological impact of our products. These materials have the potential to be a game changer in the high-value composites market.” Read more about this trailblazing partnership on the new Sonichem website. About Sonichem Sonichem (formerly Bio-Sep) is an award-winning clean tech company dedicated to pioneering green chemical production through innovative ultrasonics. Our proprietary technology transforms low-value woody biomass into valuable green chemicals, with applications spanning bio-based materials, resins and composites, pharmaceuticals, cosmetics and more. This sustainable solution is currently being showcased at our industrial-scale pilot plant, with plans in place to build a commercial biorefinery. About CPI CPI catalyses the adoption of advanced technologies and manufacturing solutions to benefit people, places, and our planet. We’re a pioneering social enterprise that accelerates the development, scale-up and commercialisation of smart AgriFoodTech, energy storage, HealthTech, materials, and pharma innovations. Through our incredible innovation experts and infrastructure, we look beyond the obvious to transform healthcare and drive towards a sustainable future. As a trusted partner of industry, academia, government, entrepreneurs and the investment community, we connect the dots within the innovation ecosystem to make great ideas and inventions a reality. We believe by working together we can build a better collective future, and as part of the High Value Manufacturing Catapult, we facilitate access to world-class organisations to deliver transformation across industries and landscapes. Creating lasting global impact from the North of England and Scotland, we invest in people and disruptive technologies to invigorate economies, create circular supply chains and make our world a better place. About the NCC The National Composites Centre (NCC) is the UK’s world-leading composite research and development facility, where innovators come when they need to make things lighter, stronger, smarter and more sustainable. Its key focus areas are composites, digital engineering, hydrogen and sustainability. With access to 'beyond' state-of-the-art technology and the best composites engineering capabilities in the world, the NCC collaborates with customers to solve the most complex engineering challenges of our time. Part of the High Value Manufacturing Catapult, the NCC works across all manufacturing sectors and has forged strong links with aerospace, energy, defence, space, construction, infrastructure, auto, rail, marine and biomedical fields. It works with organisations across the board from micro enterprises and SMEs to disrupters, the supply chain and OEMs, providing businesses with a de-risked environment to design, develop, test and scale their ideas and get them to market fast. For more information, visit https://www.nccuk.com/ About Scott Bader Scott Bader is an employee-owned global manufacturer of advanced composites, structural adhesives and functional polymers. Established in 1921, we have a century of expertise in manufacturing high-quality, innovative products for a variety of markets around the world. Scott Bader now employs 800 people across seven manufacturing sites and 18 offices worldwide. Scott Bader is committed to expanding its global reach, with recent ventures including North America, India, Japan and Australia, while continuing to build on its reputation for innovation, outstanding quality and technical expertise. About SHD Composites SHD Composites Group operates through four manufacturing sites in the UK, Europe and USA, and is a well-established industry supplier of high-quality structural and tooling prepreg materials. Accredited to AS9100 Rev D and ISO 9001:2015, SHD prides itself on its quality, service and responsiveness to local customer needs. © 2024 kdm communications limited Contact Details Editorial contact for further information or follow-up Alex Rowthorn at kdm communications limited, St Neots, UK +44 1480 405333 ideas@kdm-communications.com Company Website https://sonichem.com/

January 30, 2024 09:58 AM Eastern Standard Time

Sonichem Launches Project to Transform the Automotive Industry with Bio-Based Plastics

Sonichem

A consortium led by sustainable technology innovator Sonichem has been granted nearly £600,000 in funding from Innovate UK ’s 'Resource efficiency for materials and manufacturing' (REforMM) program. The funding will accelerate the development of the proprietary Sonichem ultrasound technology and the production of renewable, cost-effective alternatives to petrochemicals commonly used in the production of plastics, resins, and composites within the automotive industry. The cutting-edge CARMA (carbon-neutral agroforestry-derived resins to materials for automotive applications) project will apply Sonichem’s ultrasonic processing technique to automotive applications for the first time. The patented breakthrough approach converts sawdust, the biomass by-product from forestry operations, into high-quality lignin. This renewable material will then serve as the basis for bio-based platform chemicals, creating green alternatives to conventional petrochemical-derived materials currently used to produce various vehicle components. This transformative initiative is being undertaken in collaboration with technology innovation catalyst CPI, the National Composites Centre (NCC), Scott Bader, SHD Composites and Polestar, with each industry leader contributing its own specialized knowledge and expertise. In particular, CPI will support scale-up of the Sonichem technology; Scott Bader will pioneer the development of high-performance, sustainable composite resin formulations; and the NCC, SHD Composites and Polestar will together explore the potential of these novel materials for automotive interiors applications. The CARMA project aligns with the UK Government's focus on resource-efficient, sustainable industrial materials as it aims to significantly reduce the UK’s reliance on imported composite materials, which currently amounts to approximately £250-260 million per year. The newly awarded funding from Innovate UK will enable the international consortium to establish a robust and renewable lignin supply chain within the UK and accelerate the formulation of sustainable plastics and resins that contribute to steering the automotive industry toward a net-zero future and enhancing the country’s bioeconomy. Adrian Black, CEO of Sonichem, said: “We're extremely pleased to have the backing of Innovate UK's REforMM programme for this strong industrial consortium. This funding is a catalyst in our quest to offer the automotive industry a sustainable alternative to petrochemical-derived plastics. With Sonichem's ultrasound technology and the collaborative expertise of our partners, we are set to make strides toward a net-zero future and strengthen the UK's bioeconomy.” David Fishpool, Verification Manager at the NCC, said: “Creating a sustainable future is at the core of our mission. The National Composites Centre is proud to be part of this transformative initiative to accelerate the development of sustainable, cost-effective alternatives to petrochemicals in the production of plastics, resins, and composites for the automotive industry. Our role in this project underscores our commitment to driving innovation and sustainability in the materials sector. We eagerly anticipate contributing our expertise to this vital effort today, for a greener tomorrow.” Steven Brown, Group Sustainable Technology Manager at Scott Bader, commented: “Scott Bader is pleased to be part of this exciting project, and we look forward to working with our highly regarded industrial and technology partners to accelerate the valorization of abundant and sustainable biomass towards high-performance materials.” Nick Smith, Technical Director at SHD Composites, said: “SHD Composite Materials Ltd. is very excited to be working with Sonichem on the next generation of sustainable resins wholly sourced from UK feedstocks as part of our ongoing commitment to reduce the ecological impact of our products. These materials have the potential to be a game changer in the high-value composites market.” Read more about this trailblazing partnership on the new Sonichem website. About Sonichem Sonichem (formerly Bio-Sep) is an award-winning clean tech company dedicated to pioneering green chemical production through innovative ultrasonics. Our proprietary technology transforms low-value woody biomass into valuable green chemicals, with applications spanning bio-based materials, resins and composites, pharmaceuticals, cosmetics and more. This sustainable solution is currently being showcased at our industrial-scale pilot plant, with plans in place to build a commercial biorefinery. About CPI CPI catalyzes the adoption of advanced technologies and manufacturing solutions to benefit people, places, and our planet. We’re a pioneering social enterprise that accelerates the development, scale-up and commercialization of smart AgriFoodTech, energy storage, HealthTech, materials, and pharma innovations. Through our incredible innovation experts and infrastructure, we look beyond the obvious to transform healthcare and drive towards a sustainable future. As a trusted partner of industry, academia, government, entrepreneurs and the investment community, we connect the dots within the innovation ecosystem to make great ideas and inventions a reality. We believe by working together we can build a better collective future, and as part of the High Value Manufacturing Catapult, we facilitate access to world-class organizations to deliver transformation across industries and landscapes. Creating lasting global impact from the North of England and Scotland, we invest in people and disruptive technologies to invigorate economies, create circular supply chains and make our world a better place. About the NCC The National Composites Centre (NCC) is the UK’s world-leading composite research and development facility, where innovators come when they need to make things lighter, stronger, smarter and more sustainable. Its key focus areas are composites, digital engineering, hydrogen and sustainability. With access to 'beyond' state-of-the-art technology and the best composites engineering capabilities in the world, the NCC collaborates with customers to solve the most complex engineering challenges of our time. Part of the High Value Manufacturing Catapult, the NCC works across all manufacturing sectors and has forged strong links with aerospace, energy, defense, space, construction, infrastructure, auto, rail, marine and biomedical fields. It works with organizations across the board from micro enterprises and SMEs to disrupters, the supply chain and OEMs, providing businesses with a de-risked environment to design, develop, test and scale their ideas and get them to market fast. For more information, visit https://www.nccuk.com/ About Scott Bader Scott Bader is an employee-owned global manufacturer of advanced composites, structural adhesives and functional polymers. Established in 1921, we have a century of expertise in manufacturing high-quality, innovative products for a variety of markets around the world. Scott Bader now employs 800 people across seven manufacturing sites and 18 offices worldwide. Scott Bader is committed to expanding its global reach, with recent ventures including North America, India, Japan and Australia, while continuing to build on its reputation for innovation, outstanding quality and technical expertise. About SHD Composites SHD Composites Group operates through four manufacturing sites in the UK, Europe and USA, and is a well-established industry supplier of high-quality structural and tooling prepreg materials. Accredited to AS9100 Rev D and ISO 9001:2015, SHD prides itself on its quality, service and responsiveness to local customer needs. © 2024 kdm communications limited Contact Details Editorial contact for further information or follow-up Alex Rowthorn at kdm communications limited, St Neots, UK +44 1480 405333 ideas@kdm-communications.com Fax +44 1480 477833 Company Website https://sonichem.com/

January 30, 2024 09:55 AM Eastern Standard Time

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p0 launches from stealth with $6.5m to stop catastrophic software failures using Generative AI

p0 Inc

In an increasingly competitive and malicious environment vulnerabilities in enterprise codebases can lead to catastrophic security failures. Many times these can be fatal for businesses built on a foundation of customer trust and reliability. Data security is the most fundamental promise that a business can make to its users. Despite this, we have grown accustomed to hearing about massive data exploits on an almost daily basis. It is logical that recent research has found that 71% of software engineers are concerned about software reliability at their workplace. p0 has launched from stealth and today announces that it has raised $6.5m from Lightspeed Venture Partners with participation from Alchemy Ventures to help stop catastrophic software failures. p0’s proprietary technology leverages Large Language Models (LLMs) to identify safety and security issues in software before it is ever run in a production environment. p0’s technology provides a single-click solution with no need for additional user configuration. p0 can handle a wide range of software issues including data integrity issues and validation failures (including those affecting data security), alongside speed and timeout issues. p0 noiselessly surfaces intelligent and actionable output far more effectively than traditional software reliability and security solutions. Through developer teams simply connecting their Git code repositories to p0, they can rapidly gain insight beyond what traditional rule-based static analysis tools can provide - with the ability to run code scans in just 1-click. Prakash Sanker, Co-Founder and CTO of p0 said: “Across the world, recent catastrophic software failures have led to real-world impact on human life and poor outcomes for businesses. At p0, we are determined to stop these safety and security issues affecting our society. Leveraging AI, we can go further than traditional software reliability and security tools to ensure society sees the benefits of technology with less risk.” Kunal Agarwal, Co-Founder and CEO of p0 commented: “We’re building a phenomenal team and product at p0, all focussed around protecting our clients and their users the damage that software vulnerabilities and reliability bugs can cause. “As software becomes more intricate and pervasive, the importance of robust testing and reliability checks has never been more apparent. p0 is here to fundamentally change how organisations tackle these challenges head-on by harnessing the analytical power of AI. Our innovative approach empowers developers to write safer, more secure code thereby pre-empting serious run-time failures and exploits..” Before founding p0, Sanker studied maths and computer science at Stanford University and worked at companies including Palantir. Agarwal, an economics graduate from Harvard College, has previously founded a company backed by Lightspeed, Priority Vendor Technologies, which was acquired by Kansas-based C2FO in 2019. p0 will use the capital to develop its product further, as it seeks to gain adoption from more users and build its team further. Hemant Mohapatra, Partner at Lightspeed, commented: "“At Lightspeed we’ve backed over 50 companies using generative AI to create new markets and upend old ones. p0’s cutting-edge approach to code and API security is unique and amongst the first ever truly LLM-native ways of solving this age-old and ever-evolving problem. We are excited to have incubated and backed them from when this was just an idea on paper” About p0 Founded by Prakash Sanker and Kunal Agarwal, p0 leverages AI to help software teams surface critical security issues in software before their code is deployed to production. Through connecting with Git code repositories, p0 can identify a variety of software issues, using Generative AI to go further in identifying bugs than other tools can. For more information, please visit https://p0.inc/ About Lightspeed Lightspeed is a global multi-stage venture capital firm focused on accelerating disruptive innovations and trends in the Enterprise, Consumer, and Health sectors. Since 2000, Lightspeed has backed entrepreneurs and helped build companies of tomorrow, including: Affirm, Acceldata, AppDynamics, Darwinbox, Hasura, Nutanix, OYO, Razorpay, Snap, Supabase, and Udaan. Lightspeed and its affiliates currently manage more than $18 Billion across the global Lightspeed platform, with investment professionals and advisors in India, Silicon Valley, Israel, China, Southeast Asia and Europe. www.lsip.com Contact Details p0 Bilal Mahmood +44 7714 007257 b.mahmood@stockwoodstrategy.com Company Website https://p0.inc/

January 30, 2024 09:00 AM Eastern Standard Time

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Locality and Canela Media Join Forces To Amplify Hispanic Political Engagement

Locality

Locality, the industry’s preeminent local video solutions provider, today announced a partnership with Canela Media, the leading technology and innovation-driven digital media company for the Latino community. Locality will act as the Hispanic-media company’s exclusive political ad sales arm and oversee political campaign engagement strategies targeted toward Hispanic audiences this election year. The synergy of Canela Media's trust and credibility within Hispanic communities and Locality's expertise in political and streaming advertising promises a groundbreaking approach to local political outreach. This collaboration will facilitate reach among the U.S. Hispanic audience through Canela Media’s streaming inventory while leveraging Locality’s industry prowess and capabilities to sell digital inventory for political campaigns. This collaboration acknowledges the growing and important Hispanic population of eligible voters in the upcoming November 2024 election. According to Pew Research, over 36.2 million Hispanic Americans will be eligible to vote, constituting 14.7% of all eligible voters, an increase from 13.6% in 2020. “We are thrilled to announce our strategic partnership with Locality, a collaboration that enables political advertisers to establish meaningful connections with the growing and influential Canela Media audience. Recognizing the crucial role of engaging with U.S. Hispanic voters.” Andrés Rincón, Senior Vice President of Sales at Canela Media, emphasized, "Canela Media’s expansive reach and scale uniquely position us to connect with over 50 million U.S. Hispanics through our comprehensive OTT/CTV and online offerings.” “We’re excited to join forces with Canela Media to help transform how political advertisers are reaching underrepresented communities,” said Stacey Perry, Vice President of Political Streaming at Locality. “This partnership comes at a time when it’s more important than ever to reach Hispanic voters across all communities. By combining our political media expertise with Canela Media, we’re coming together to ensure local political advertisers can connect with Hispanic communities across all media avenues and keep them educated during this election cycle. About Locality Locality is the industry's preeminent local video solutions provider, committed to addressing the evolving needs of advertisers by unlocking the power of local and driving dollars to the local video marketplace. Locality brings together the best talent in both broadcast and streaming helping brands tap into the mindset of the local consumer and precisely reach optimal markets, nationally. Having served more than 1,500 ad agencies and 4,500 advertisers, to date, Locality offers the best premium inventory that the industry has to offer to help brands optimize their spend and target audiences at scale. Our team resides in 11 office locations across the U.S. designed to strategically service 100% of DMAs. For more information, please visit www.locality.com. About Canela Media Canela Media is a leading technology and innovation driven media company offering brands a complete ecosystem to connect with multicultural audiences starting with its free streaming platform service, Canela.TV enriching the new generation of U.S. Latinos with free access to unique, culturally relevant content which includes a unique blend of music programming through Canela Music featuring emerging and established Latino artists, Spanish-language Children's content through Canela Kids and sports content through Canela Deportes. As part of Canela Mediaâs proprietary data solution offering, Canela Connect is centered on an OTT first approach that helps identify U.S. Hispanic audiences in English and Spanish language OTT platforms providing unprecedented OTT scale for advertisers to reach U.S. Hispanics. Moreover, Canela Media's large scale in premium Spanish-language sites, combined with the company's proprietary data, provides in-depth knowledge and understanding of how to establish meaningful and culturally relevant connections with the new mainstream Hispanics across the U.S. and Latin America. For more information, please visit http://www.CanelaMedia.com. Contact Details Kite Hill PR for Locality +1 973-722-7881 julia@kitehillpr.com

January 30, 2024 09:00 AM Eastern Standard Time

American Medical Association Grants Cardio Diagnostics (NASDAQ: CDIO) Reimbursement Codes For AI-Powered Coronary Heart Disease Tests

Cardio Diagnostics Holdings, Inc

By Jeremy Golden, Benzinga Cardio Diagnostics’ AI-driven coronary heart disease (CHD) tests have taken another promising step in their evolution. Cardio Diagnostics (NASDAQ: CDIO), an artificial intelligence-powered precision cardiovascular medicine company, has been assigned two dedicated Current Procedural Terminology (CPT) Proprietary Laboratory Analysis (PLA); 0440U for the company’s AI-driven CHD detection test, PrecisionCHD, and 0439U for the company’s AI-driven CHD event (heart attack) risk assessment test, Epi+Gen CHD. Assigned by the American Medical Association (AMA), these two new CPT PLA codes – effective April 1, 2024 – mark a significant step toward payer billing and payment for the company’s groundbreaking tests. The designation will facilitate the broader adoption of PrecisionCHD, an integrated genetic-epigenetic clinical blood test to aid in the diagnosis of CHD, and Epi+Gen CHD for evaluating the likelihood of a patient experiencing a CHD event – mainly a heart attack – within the next three years. Treating A Growing Problem Every year, about 805,000 people in the United States have a heart attack, meaning someone experiences a heart attack every 40 seconds. Heart disease is the leading cause of death for both men and women. According to the CDC, in 2021, heart disease was responsible for the deaths of more than 695,000 Americans – representing one in every five deaths. The most common type of heart disease and the major cause of heart attacks, CHD was responsible for over 375,000 deaths in 2021, and CHD-associated medical costs are estimated to be about $239.9 billion according to an estimate by the CDC in its heart disease fact sheet. Combating this growing problem, Cardio Diagnostics reports that PrecisionCHD is the first integrated genetic-epigenetic test for the detection of CHD. The PrecisionCHD test has the ability to aid in the diagnosis of CHD and provide personalized insights to help prevent a heart attack and improve outcomes. With the introduction of PrecisionCHD, clinicians are armed with a powerful, scalable and non-invasive alternative that comes in the form of a blood-based test that uses artificial intelligence, along with personalized genetic and epigenetic information, to sensitively detect the presence of CHD. Identifying patients with CHD and intervening before a heart attack occurs are essential to reducing the unprecedented economic and health burden associated with CHD. Until now, the lack of readily accessible and cost-effective diagnostic solutions for CHD has posed a challenge leading to delayed diagnosis and care, particularly among underserved and minority populations. Increasing access, the PrecisionCHD test only requires a simple blood draw and can be deployed remotely, allowing it to be scaled without the need for specialized infrastructure. This enables more timely intervention and management. “Receiving a dedicated CPT PLA code for PrecisionCHD is a critical milestone in our commercialization strategy,” said Meesha Dogan, Ph.D., CEO and Co-Founder of Cardio Diagnostics. “With PrecisionCHD, we believe that expanding equitable access to CHD diagnostics and improving patient health outcomes while reducing healthcare expenditure is possible.” While PrecisionCHD aids in diagnosing CHD, Cardio Diagnostics’ Epi+Gen CHD evaluates an individual’s genetic and epigenetics to predict their risk for a heart attack or sudden cardiac death associated with CHD. By leveraging the powerful personalized insights driven by the company’s groundbreaking epigenetic-genetic technology, the company can provide patient-specific epigenetic and genetic drivers of CHD to help guide preventive care that could potentially save lives. In peer-reviewed studies, Epi+Gen CHD was more cost-effective and sensitive for assessing heart attack risk when compared to standard lipid-based risk calculators. Specifically, in a validation study conducted with Intermountain Healthcare, Epi+Gen CHD was shown to be, on average, about twice as sensitive in detecting risk for a CHD event in women than lipid-based calculators. For employers, the financial burden of heart attacks includes direct costs related to diagnosing, managing and treating heart disease. Indirect costs include lost productivity due to employee absenteeism and short-term disability, which can indirectly cost employers about $1,119 per month for upwards of three years. Cardio Diagnostics’ technology can help employers better inform their benefits offerings by combining the ability to offer employees the advanced Epi+Gen CHD heart attack risk test with aggregated risk data. Cardio Diagnostics’ Employer Risk Intelligence platform provides employers and brokers with the first-of-its-kind cardiovascular employee population health intelligence backed by a clinical test and layered insights, completed in a compliant manner. As such, Epi+Gen CHD’s new reimbursement code could mean greater access to technology that enables a healthier workforce and significant savings in healthcare costs related to heart disease. “Cardio Diagnostics is committed to driving widespread adoption of our solutions, and obtaining a reimbursement code for Epi+Gen CHD is a critical milestone in our commercialization strategy and for gaining reimbursement from federal and private payers,” Dogan said. Cardio Diagnostics continues to lead the way in precision cardiovascular medicine, leveraging the power of AI and epigenetics to help prevent heart attacks. The company is committed to making heart disease risk assessment, detection and management more accessible, and it believes personalized and precise diagnostics are key to winning the fight against the leading cause of death in the United States. Cardio Diagnostics is an artificial intelligence-powered precision cardiovascular medicine company that makes cardiovascular disease prevention, detection, and management more accessible, personalized, and precise. The Company was formed to further develop and commercialize clinical tests by leveraging a proprietary Artificial Intelligence (AI)-driven Integrated Genetic-Epigenetic Engine (“Core Technology”) for cardiovascular disease to become one of the leading medical technology companies for improving prevention, detection, and treatment of cardiovascular disease. For more information, please visit www.cardiodiagnosticsinc.com. Certain statements and information included in this press release constitute "forward-looking statements" within the meaning of the Private Securities Litigation Act of 1995. When used in this press release, the words or phrases “will”, "will likely result," "expected to," "will continue," "anticipated," "estimate," "projected," "intend," “goal,” or similar expressions are intended to identify "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements are subject to certain risks, known and unknown, and uncertainties, many of which are beyond the control of the Company. Such uncertainties and risks include but are not limited to, our ability to successfully execute our growth strategy, changes in laws or regulations, economic conditions, dependence on management, dilution to stockholders, lack of capital, the effects of rapid growth upon the Company and the ability of management to effectively respond to the growth and demand for products and services of the Company, newly developing technologies, the Company’s ability to compete, regulatory matters, protection of technology, the effects of competition and the ability of the Company to obtain future financing. An extensive list of factors that can affect future results are discussed in the Current Report on Form 10-K for the period ended December 31, 2022 and Form 10-Q for the period ended March 31, 2023, under the heading “Risk Factors” in Part I, Item IA thereof, and other documents filed from time to time with the Securities and Exchange Commission. Such factors could materially adversely affect the Company's financial performance and could cause the Company's actual results for future periods to differ materially from any opinions or statements expressed within this press release. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Gene Mannheimer - Investor Relations +1 855-226-9991 investors@cardiodiagnosticsinc.com Company Website https://cardiodiagnosticsinc.com/

January 30, 2024 08:20 AM Eastern Standard Time

How Lytus Digital’s Technology Partnership Services Are Emerging As A Catalyst For Innovation

Benzinga

By Meg Flippin, Benzinga To outsource or not is no longer a question of money, it is whether a company can innovate on its own. Increasingly, the answer is no – not without incurring extra costs and untold headaches. An in-house approach to IT comes at a premium, encompassing substantial costs such as high salaries, office spaces and perks to lure top talent. Economic downturns and layoffs can stall projects that are necessary to stay ahead of rivals. Standing still isn’t an option either. Studies show companies that embrace technology have a lead over those who don’t. Take a recent analysis of the banking sector by Harvard Business Review. From 2018 through 2022 digital leaders achieved total shareholder returns of 8.1% versus 4.9% for laggards. Why? Because technology helped them grow revenue and better contain expenses. Lytus Digital is capitalizing on the growing importance of digital transformation through its leading-edge solutions. The Speed Of Change From artificial intelligence to mixed reality, technological innovations are happening at a breakneck speed. Even if an enterprise has the means, implementing these innovations is proving difficult to do, which is why outsourcing is in such demand. The global IT services outsourcing market was valued at $639.59 billion in 2022 and is poised to grow at a compound annual growth rate (CAGR) of 8.0% from 2023 to 2030. Driving a lot of that growth is spending on software. Forecasts expect software sales to increase 12.3% in 2023 and 13.1% in 2024. Companies are looking to increase automation and productivity and are spending their investment dollars on software to achieve that. Growth is also being driven by rapid innovations that empower businesses to meet the changing demand of the commercial environment and better access innovation and intellectual property. That demand plays into Lytus Technologies Holdings Ptv. Ltd.'s (NASDAQ: LYT) sweet spot. The platform services company enriching the experience for users whether it’s streaming content, telemedicine or fintech services, recently launched Lytus Digital. Lytus Digital offers a suite of technology solutions to help enterprises explore and integrate cutting-edge technologies such as artificial intelligence, virtual and mixed reality and low-code rapid application development into their operational frameworks. Lytus Digital specializes in delivering advanced technological solutions tailored for enterprises, leveraging the power of next-generation technologies. The company is developing an ecosystem of modular platforms and customizable solutions that ensures a smooth integration into their clients’ existing business processes. All of that enables companies to embrace innovation with less risk. The last thing any enterprise can afford is to invest time and money into building a system that doesn’t work or can’t integrate. Every Industry Needs Digitalization Out of the gate, Lytus is going after the global SME sector which has long been ignored by tech providers. Lytus Digital creates superior technical strategies customized to their clients’ requirements while utilizing deep tech like artificial intelligence, IoT and machine learning. This allows the company to build out custom and modular products to give their customers a competitive edge. It’s not just SME firms that need a digital overhaul. Industry after industry is looking for digital innovation and to get it as easily and seamlessly as possible. “With this pursuit, we aim to establish strong partnerships in the industry to boost multinational growth, and to build accessible leading-edge technology-enabled products and solutions across various verticals,” Lytus’s board of directors said when announcing the new offering. Partnering For Innovation This idea of partnering to tap innovation is gaining popularity for good reason. By partnering with companies like Lytus Digital, enterprises can get access to what Lytus says are cost-effective technical solutions and specialized talent proficient in the latest technologies. Not to mention, they don’t have to worry about outages and downtimes, something many can’t say about their own in-house IT departments. The world is changing at a dizzying speed. Thanks to AI, machine learning, software-as-a-service, big data and a bevy of other technological advancements and innovations, companies have boosted revenue, gained new customers and cut costs. But going it alone is difficult. The ones that don’t do anything stand to fail. The ones that do it on their own, have to pay a premium. Lytus Technologies is changing that with Lytus Digital. It is leveling the playing field, taking the costs out of the equation and enabling even the smallest business to have the same cutting-edge technology as their larger rivals. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

January 30, 2024 08:15 AM Eastern Standard Time

Nature Medicine Publishes Updated Preliminary Phase 1 Data From Elicio Therapeutics' AMPLIFY-201 Phase 1 Solid Tumor Study Of ELI-002

Benzinga

By Jeremy Golden, Benzinga Colorectal cancer (CRC) and pancreatic ductal adenocarcinoma (PDAC) are the second and third leading causes of cancer death, respectively. Pancreatic and colorectal cancers are often Kirsten rat sarcoma (KRAS) mutated and are incurable when tumor DNA or protein persists or recurs after curative intent therapy. KRAS mutations are among the most prevalent human cancers. For these cancers, caused by a mutation of the KRAS gene, clinical-stage biotechnology company Elicio Therapeutics Inc. (NASDAQ: ELTX) is developing a pipeline of novel immunotherapies for treatment. Founded in 2011, Elicio Therapeutics has developed an innovative pipeline of cancer immunotherapies addressing critical unmet needs. Three vaccine candidates are currently in Elicio Therapeutics’ pipeline: ELI-002, ELI-007 and ELI-008. Elicio’s lead clinical program, ELI-002, is a structurally novel investigational AMP therapeutic immunotherapy targeting mutant KRAS-driven cancers. It was designed to stimulate an immune response against the seven KRAS mutations driving 25% of solid tumors. ELI-002 2P has been studied in a phase 1 dose-escalation study in patients with high relapse risk mKRAS-driven solid tumors, following surgery and chemotherapy. After early findings from AMPLIFY-201 were released, ELI-002 was the subject of a publication in Nature Medicine. The paper — “ Lymph Node Targeted, mKRAS-specific Amphiphile Vaccine in Pancreatic and Colorectal Cancer: The phase 1 AMPLIFY-201 Trial ” — details expanded and updated results that point to the power of Elicio Therapeutics’ use of precision vaccines, immunomodulators and cell-based therapies to assemble cancer-killing immune responses against solid tumors. Originally presented at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting and the 2023 AACR Special Conference on Pancreatic Cancer, the data detailed in the publication is as of September 6, 2023. It is based on 25 patients with solid tumors (20 pancreatic, 5 colorectal) who were positive for minimal residual mKRAS disease after locoregional treatment. “When tumor DNA or protein persists or recurs after treatment, patients with pancreatic and colorectal cancers are unfortunately not left with many options and are often incurable,” said study author Shubham Pant, M.D., Associate Professor of Gastrointestinal Medical Oncology at The University of Texas MD Anderson Cancer Center. “These are promising early findings from the AMPLIFY-201 study with follow up ongoing. Most patients reduced their tumor biomarkers with some having complete clearance following treatment with ELI-002.” “The lymph node-targeted cancer vaccine candidate induced direct ex vivo mKRAS-specific T cell responses in 84% of patients, with 59% of patients demonstrating a response with two key types of T cells: helper cells and killer cells,” according to Christopher Haqq, M.D., Ph.D., Elicio’s Executive Vice President, Head of Research and Development, and Chief Medical Officer. “Past studies have not produced this large a fraction of patient response, this high a magnitude of a response or the expansion of both key populations of T cells,” he said. “Importantly, these T cell responses were specific to tumor-driver mutant KRAS neoantigens, correlated with reduced risk of relapse and we saw a pool of memory T cells form that we believe hold promise to confer long-term protection,” Haqq said. “We look forward to progressing ELI-002 into a randomized phase 2 trial as a monotherapy for patients with PDAC.” ELI-002 7P is currently being studied in AMPLIFY-7P, a phase 1/2 trial in patients with high relapse risk mKRAS-driven solid tumors. The ELI-002 7P formulation is designed to provide immune response coverage against seven of the most common KRAS mutations, thereby increasing the potential patient population for ELI-002 and possibly reducing the chance of bypass resistance mechanisms. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

January 30, 2024 08:10 AM Eastern Standard Time

Sprott’s Energy Transition ETFs: A Look Back And A Look Ahead

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By Austin DeNoce, Benzinga Sprott is a leader in precious metals and energy transition investments, making strides in the evolving move to cleaner energy. With the launch of five new Exchange Traded Funds (ETFs) in the first quarter of 2023, Sprott has expanded its offerings for investors to find pure-play exposure to the critical minerals essential for cleaner energy production and storage. Overview Of The Sprott Energy Transition ETFs The year 2023 has exhibited a pivotal shift in the energy sector, with increasing global mandates for reduced carbon emissions increasingly driving capital and interest toward viable energy alternatives. Sprott's Energy Transition ETFs – SETM, LITP, URNM, URNJ, COPJ and NIKL – provide a targeted approach for investment in miners of vital minerals like lithium, uranium, copper, nickel and others pivotal in the broader energy transition. John Ciampaglia, CEO of Sprott Asset Management, emphasizes the critical role of these minerals in meeting the escalating demand for low-carbon energy solutions. He also highlights the existing gap between supply and demand, largely due to historical underinvestment. This scenario presents a unique opportunity for mining companies in this domain, poised to capitalize on the potential impending surge in investment. Market Trends With each of these new ETFs, Sprott aims to provide investors the opportunity to capitalize on the potentially sizable growth of the low-carbon energy markets throughout this decade. In 2023, the global lithium market was roughly $8.2 billion, but it is estimated to see a compound annual growth rate (CAGR) of 12.8% from 2024 all the way to 2030. Meanwhile, the uranium market is expected to grow at a CAGR of 7.06% up to 2027, while copper is estimated to see a CAGR of 4.21% through 2029. Market predictions are always subject to the possibility of error, especially when forecasting far into the future, but there are only a handful of minerals capable of filling the void left by fossil fuels. The extent to which the broader energy transition materializes is to be seen, but markets will have to rely heavily on one or all of the viable alternatives if we are to make any meaningful progress toward decarbonization. Individual ETF Focus Each ETF in Sprott's portfolio offers a unique investment opportunity within the energy sector: SETM: Focused on a broad range of critical minerals essential in the transition to clean energy. LITP: Concentrated on the lithium industry critical to meeting increasing electric vehicle (EV) demand, including lithium producers, developers and explorers. URNM: Tracks the performance of companies that devote 50%+ of assets to the uranium mining industry. URNJ: Targeted at small-cap uranium miners integral to the nuclear energy sector. COPJ: Centered on small-cap miners in the copper industry, which are essential for electrical infrastructure across industries. NIKL: Tracks the performance of a selection of securities in the nickel industry, including producers, developers and explorers. 2023 Performance Analysis Despite a troubling year battling the steep rise in interest rates, the long-term outlook of Sprott’s energy ETFs remains focused on the vital role of these minerals in the burgeoning low-carbon energy sector, particularly in EVs. “As the global energy transformation advances, a new commodity supercycle is emerging.” Sprott’s Jacob White CFA, and Paul Wong, CFA and Market Strategist said. The year-to-date performances of Sprott’s Energy Transition ETFs are as follows: SETM: -11.60% LITP: -35.77% URNM: 56.88% URNJ: 20.05% COPJ: -7.18% NIKL: -18.43% Looking Ahead to 2024 As we approach 2024, the market outlook remains cautiously optimistic. The potential growth in the energy transition materials market is closely tied to global policies and economic factors. While challenges are inevitable, the potential opportunities in this sector remain substantial, especially given the increasing focus on sustainable energy solutions and government-driven mandates and incentives such as those outlined in the Inflation Reduction Act. “Global metal consumption is forecasted to rise in 2024, fueled by the burgeoning renewable energy sector and the EV market. This "green boom" is expected to offset sluggishness in more traditional industries.” Sprott’s Jacob White CFA, and Paul Wong, CFA and Market Strategist said. The Energy Evolution Investing in Sprott's energy transition ETFs offers a strategic pathway for investors to align with the global shift toward sustainable energy through a variety of commodity subsectors. While the investment landscape in each sector is subject to its supply and demand dynamics, the underlying trend toward cleaner energy solutions underscores the potential for growth and the importance of these investments in a diversified portfolio. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

January 30, 2024 08:05 AM Eastern Standard Time

These Two Assets Historically Limited To Ultra-Wealthy Investors Have Seen Triple Digit Returns Over The Past Decade – Vint Expands Access With Latest Fund

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By Meg Flippin, Benzinga Invest in long-term appreciation opportunities through fine wine and rare whisky here. Great taste and a nice buzz aren’t the only things you can toast when it comes to fine wine and rare whisky. There’s also the potential for a nice return on them as asset classes. Over the past few years, fine wine and rare whisky prices have witnessed growth as investors turn to them as a way to diversify and hedge against inflation. The Knight Frank Fine Wine Icons Index (KFFWII), which tracks a sector of wines that represent the fine wine investment market, is up 149% over the past ten years. Meanwhile, the Knight Frank Rare Whisky index, which tracks the auction results of a basket of rare Scottish single malts, is up 586% over the past decade. Leveling The Playing Field Despite the returns, getting access to this multi-billion dollar market historically favored by the ultra-wealthy can be difficult for regular investors. Historically, industry insiders and members of hard-to-get-on allocation lists are the ones who get to take part in this alternative investment opportunity. That’s changing thanks to companies like Vint. The platform for wine and spirits collection investing is leveling the playing field through its equity products and marketplace, giving investors and consumers access to fine wine and rare spirits with the potential for long-term appreciation. Learn more about the fine wines and whiskies at Vint’s marketplace. Vint’s innovation aims to capitalize on emerging trends while improving access to these investment opportunities. Demand for the top French wines is growing at the same time that access to them is proving difficult. That has created what the company says is a significant pricing delta among the U.S., Europe and Asia for many of these assets. Through its funds, Vint aims to give investors an efficient and tax-advantaged investment product to capitalize on this arbitrage. The company uses collected investor capital to buy physical bottles and cases of wine and whisky in one region and sell them in another. Once an asset sale is made, Vint reinvests the funds and any gains into new purchases. Best Of Both Worlds With Vint’s New Fund To encapsulate that opportunity in both the wine and whisky markets, Vint recently launched the Vint Futures and Casks I (VV-FC1) fund. Open to accredited investors with a minimum investment of $2,500, the goal of the fund is to give investors a blended approach to investing in wine and spirits and capture the quality potential from recent vintages of top wine from Bordeaux and other regions while also leveraging the strong demand and trading activity of spirits casks. What drives prices for spirits casks and wine futures is the scarcity. When producers limit the release, the market value tends to soar. As it ages and is consumed, quality and scarcity increase, driving the value of the wine or whisky higher. This gives investors the potential for long-term appreciation. Over the years spirits and wine have proven to be a solid investment, outperforming the broader markets. A popular way to gain exposure to fine wine and rare whisky is through wine and spirits futures. These enable investors to invest in the assets at their release price, providing the potential for significant upside as the price increases. Bordeaux wines, known for their aging potential are one example of a wine that could provide long-term appreciation, but there are others, as well. Cask investing affords investors the same opportunity. The only difference is the aging of whisky and rum is in a barrel or cask rather than a bottle. The Vint Futures and Casks I fund gives investors the best of both worlds, with a target composition of 70% wine futures and 30% spirits casks and a projected hold time of five to six years. Get wine and whisky exposure through the Vint Futures and Casks I Fund. Knowledge Is Power Vint should know a thing or two about fine wine and aged whisky. The company has been around since 2019, offering equity products to investors who want exposure to these luxury asset classes. It also operates the Vint marketplace which sells fine wines and rare spirits to collectors, consumers and merchants. The marketplace was created to give investors the best exit price for Vint investment assets all the while mitigating investment fees. At last check, the Vint marketplace had over $70 million in assets and hundreds of customers. Vint also has performance to back it up – the company has returned capital from 14 deals resulting in an average realized net IRR of 28.7%. Fine wine and rare spirits investing has long been the domain of a select few. Vint is changing that by giving more investors access to what has the potential for long-term appreciation. Now that’s something to cheer about. Use the Vint platform to invest for as little as $2500. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

January 30, 2024 08:00 AM Eastern Standard Time

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