Clene Inc. announces positive results from CNM-Au8 results from MS trial
Clene Inc
Clene Inc (NASDAQ:CLNN) CEO Rob Etherington joined Steve Darling from Proactive to share news regarding the latest findings from the long-term open-label extension (LTE) of the VISIONARY-MS trial. This trial focuses on participants with stable relapsing multiple sclerosis (MS) and represents nearly three years of follow-up research. Following the conclusion of the double-blind period of the trial, participants were given the opportunity to continue with CNM-Au8® treatment at a dose of 30mg for an additional 96 weeks during the LTE phase. The analysis encompassed the modified intent-to-treat population, which included all study participants with valid clinical data. Etherington highlighted the key finding that long-term CNM-Au8 treatment showcased improvements in vision, as measured by low contrast visual acuity, an essential assessment of visual function in individuals living with multiple sclerosis. Remarkably, these improvements in vision persisted for 35 months from randomization, demonstrating the sustained efficacy of CNM-Au8 over an extended period. Moreover, the data revealed consistent and robust overall enhancements not only in vision but also in cognition among participants treated with CNM-Au8 for nearly three years from randomization. These results are particularly noteworthy for their potential to positively impact disease progression and potentially reverse established disability, representing a significant therapeutic breakthrough for patients with MS. Full clinical results from the long-term open-label extension will be officially presented at the ninth annual Americas Committee for Treatment and Research in Multiple Sclerosis Forum, scheduled to take place from February 29 to March 2, 2024, in West Palm Beach, Florida. Clene's commitment to advancing treatments for multiple sclerosis is evident in these promising results, and their ongoing research holds great promise for enhancing the quality of life for individuals affected by this condition. The potential to offer effective long-term solutions and improve both vision and cognitive function is a significant step forward in the battle against multiple sclerosis. Contact Details Proactive Canada Proactive Canada +1 604-688-8158 action@proactiveinvestors.com
February 05, 2024 02:30 PM Eastern Standard Time
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LungLife AI announces success in Validation of LungLB in multi-site, prospective clinical study
LungLife AI Inc
LungLife AI CEO Dr. Paul Pagano joined Steve Darling from Proactive to discussed the groundbreaking lung cancer detection technology developed by the company. LungLife AI is dedicated to addressing the critical issue of early detection in lung cancer, which remains the leading cause of cancer-related deaths. Dr. Pagano highlighted the sobering statistic that 80% of lung cancer cases are detected too late, contributing to the high mortality rate associated with this disease. The company's lung lb test, which has recently undergone successful validation, is poised to revolutionize the early detection of lung cancer by addressing the challenge of evaluating small nodules under 15 millimetres in size. Early intervention is crucial in improving patient outcomes, and the lung lb test is designed to meet this unmet need. Physicians have expressed excitement about the potential of this test to transform the landscape of lung cancer detection. Unlike existing methods, the lung lb test takes a unique approach by examining circulating genetically abnormal cells in the blood. This innovative approach offers a complementary and highly sensitive means of detecting lung cancer, enhancing the chances of early intervention and improved patient prognosis. Dr. Pagano discussed the competitive landscape, emphasizing LungLife AI's patented methods and proprietary technologies that set their approach apart in the field of lung cancer detection. Looking ahead, LungLife AI plans a methodical introduction of the lung lb test through an early access program, ensuring a seamless transition into healthcare settings. The next six to twelve months will involve a commercial proof of concept, with the company collaborating with hospital sites and working towards securing coverage from insurance providers. The potential life-saving impact of LungLife AI's technology and their strategic approach to making it accessible to patients and healthcare providers mark a significant contribution to advancing the field of lung cancer detection. The company's dedication to improving early detection rates and ultimately reducing the mortality associated with this devastating disease underscores their commitment to patient care and well-being. Contact Details Proactive UK Ltd Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com
February 05, 2024 02:25 PM Eastern Standard Time
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Bluefield Solar Income Fund investment advisor on a "positive start" to 2024
Bluefield Solar Income Fund
The Bluefield Solar Income Fund (LSE:BSIF), advised by Bluefield Partners, recently announced a significant strategic partnership with GLIL Infrastructure, involving the acquisition of a 247-megawatt UK solar portfolio from Lightsource bp. Bluefield Partners' Managing Partner James Armstrong visits the Proactive London studio to speak with Thomas Warner to talk about how the agreements fits into the fund's long-term strategy of delivering attractive, inflation-linked dividends to its shareholders. Armstrong highlights the three key components of this partnership. Firstly, the acquisition of the Lightsource bp portfolio, which he praises for its diversity, proven management, and high levels of regulated revenues, aligning closely with the fund's objective of providing long-term, inflation-linked returns. About 80% of the revenues from this acquisition are linked to inflation, making it a potentially more attractive proposition for the fund's shareholders. The second phase of the partnership involves selling a 50% stake to GLIL. This move is aimed at reducing the fund's short-term debt burden, which has been a challenge due to the broader market's recent struggles with higher inflation and interest rates, leading to lower public market valuations of infrastructure and renewable energy assets. The third phase focuses on joint development of a pipeline of new assets over the next 2-5 years, leveraging the fund's strong market position and decade-long track record of high performance. In response to potential shareholder reactions, Armstrong anticipates positive support, citing ongoing discussions with them. He says its been a "reasonably positive start" to the year after a challenging 2023. Contact Details Proactive UK Ltd Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com
February 05, 2024 02:01 PM Eastern Standard Time
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Skeena Resources set for exciting 2024 following successful capital raise and feasibility study
Skeena Resources Limited
Skeena Resources Director of Communications Katie MacKenzie joined Steve Darling to to discuss the company's exciting prospects for 2024, building on the significant achievements in the latter part of 2023. Skeena Resources has been on an impressive trajectory, and their latest developments are no exception. One of the noteworthy milestones for Skeena Resources was the successful closure of a flow-through common shares financing, which garnered approximately $10.7 million. This financial injection followed hot on the heels of an even more substantial financing package, totaling $81 million. This package was composed of the sale of a 1.0% Net Smelter Return (NSR) royalty on Eskay Creek, which fetched $56 million, and a $25 million unsecured Convertible Debenture. Franco-Nevada now holds a 2.5% NSR on all of Skeena's Eskay Creek properties, adding further depth to the company's strategic partnerships. MacKenzie went on to provide insights into Skeena Resources' comprehensive workplan, which revolves around building upon the recently completed Definitive Feasibility Study for their 100% owned Eskay Creek Gold-Silver Project, situated in Tahltan Territory within the Golden Triangle of northwest British Columbia. The results of this study are nothing short of impressive, with an after-tax net present value (NPV) of $2.0 billion, based on a base case scenario of $1,800 gold and $23 silver. The internal rate of return (IRR) stands at an impressive 43%, and the after-tax payback period for pre-production capital expenditures is a mere 1.2 years. These remarkable financial metrics have the potential to elevate Eskay Creek to the status of a Tier 1 gold mining project, setting the stage for a transformational journey in the gold mining industry. Skeena Resources is poised to make a significant impact in the coming year, with their financial strength, strategic partnerships, and a world-class asset like Eskay Creek firmly positioning them as a formidable player in the sector. The company's focus on value creation and growth is sure to capture the attention of investors and industry observers alike as they embark on this pivotal phase in their journey. Contact Details Proactive Canada Proactive Canada +1 604-688-8158 action@proactiveinvestors.com
February 05, 2024 01:57 PM Eastern Standard Time
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Tertre Rouge Assets aiming for "15-25% return" from classic cars and motorcycles
Tertre Rouge Assets PLC
Tertre Rouge Assets PLC CEO André Ahrlé and Chairman Steven Schapera speak to Thomas Warner from Proactive about their innovative approach to generating shareholder returns by consolidating investment-grade classic cars and motorcycles. Their strategy revolves around creating a portfolio that aims for a 15% Internal Rate of Return (IRR) and operating companies with potential returns of 20-25%. This combined approach targets an overall investor return of 15-20%. The company's board boasts deep industry knowledge and includes prominent figures like Mika Hakkinen, David Coulthard, and Allan McNish. André Ahrlé, a former professional racer and Daytona winner himself, highlights his journey from collecting Porsches to co-founding Tertre Rouge Assets. He emphasises the global appeal and iconic status of their car collection, appealing to a wide range of enthusiasts and collectors. The investment model allows shareholders to benefit from the appreciation of the entire portfolio, rather than individual assets. Looking ahead, Schapera is confident about the company’s meticulously planned future, citing an analysis by Oberon that predicts a 15-25% return. This optimism is based on the solid foundation of their car portfolio and cash-generating businesses. Contact Details Proactive UK Ltd Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com
February 05, 2024 01:51 PM Eastern Standard Time
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Sui’s Astounding DeFi Growth Continues into 2024 as TVL Breaks the $500M Barrier
Sui
After Sui’s TVL surged more than 1500% over the last five months of 2023, its TVL has more than doubled since the start of 2024 Sui, one of the fastest-growing Layer 1 blockchains, continued its impressive DeFi growth, surpassing $500M in Total Value Locked (TVL) and solidifying itself in the top 10 of DeFi ecosystems. Alongside this torrid ascent of TVL, on-chain activity has exploded as well. Weekly DeFi volume is up 63 percent over the previous period, standing at $745M and placing it in the top 5 most active ecosystems in the past week. Sui’s continued climb demonstrates how its underlying technology is vital in empowering developers to create products that solve real-world challenges and the drive behind top projects expanding into its ecosystem. Over the past couple of weeks, Sui has announced several partnerships and expansions with industry-leading builders. Most recently, Sui announced that Ondo Finance—the third-largest organization in the real-world asset DeFi sector—is bringing its treasury-backed tokens, tokenized securities, and real-world assets into its ecosystem, as the Sui ecosystem is set to get its first native stablecoin. Sui also recently announced that Banxa, a leading payments infrastructure provider for the crypto-compatible economy, will add the SUI token to its platform. Also recently announced, a partnership with Oracle Stork provides builders with faster pricing data, offering real-time pricing data across Sui’s ecosystem of developers, DEXs, and lending protocols building on Sui's blockchain. “The fact that Sui now stands amongst the top ecosystems in crypto is a testament to Sui’s technology being able to attract top-tier developers and leading projects,” said Greg Siourounis, Managing Director of the Sui Foundation. “The recent partnership and expansion announcements, along with the surging metrics, point to Sui having true staying power. Sui is paving the way for widespread adoption and offers endless possibilities for innovation.” Sui’s object-centric model, horizontal scalability, and Move Language position it to host the most scalable solutions that have emerged from the blockchain industry to date. Its rapidly rising TVL results from multiple Sui-based protocols and applications leveraging Sui's strengths. Sui also saw two ecosystem protocols break $100M TVL for the first time in the network’s history. Navi Protocol now stands at over $114M TVL (up 184% over the last 30 days), while Scallop Lend has surged to over $116M TVL (up 258% over the last 30 days). Cetus ($72M), Aftermath Finance ($58M), and FlowX Finance ($49M) round out the top five projects as measured by TVL. Contact Details Sui Foundation Sui Team media@sui.io
February 05, 2024 01:26 PM Eastern Standard Time
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Chaarat Gold makes strong progress with Tulkubash open-pit project in the Kyrgyz Republic
Chaarat Gold Holdings Ltd
Chaarat Gold Holdings Ltd (AIM:CGH) chief financial officer David Mackenzie joined Proactive's Stephen Gunnion with an overview of the company's operations in the Kyrgyz Republic, where it is advancing two significant projects on the same license: Tulkubash and Kyzyltash. Tulkubash, an open-pit project expected to produce approximately 95,000 ounces of gold annually, is nearing operational readiness. The project requires 18 months to build, with a recently completed EPC contract and is awaiting final financing. Additionally, Mackenzie highlighted the potential of the nearby Kyzyltash project, an underground venture poised to yield 350,000 ounces annually. This project, slated for a feasibility study refresh in 2025, promises to substantially enhance the company's gold production capacity. Mackenzie also discussed the strategic importance of the Kyrgyz Republic as a mining jurisdiction. The region has seen renewed interest in foreign investment, attributed to the proactive efforts of the new government, including outreach initiatives and participation in international forums. He said the company is focused on completing project financing in Q1 2024 and initiating the EPC with Power China in Q2 2024. The company anticipates first gold production by Q4 2025. Contact Details Proactive UK Ltd Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com
February 05, 2024 01:17 PM Eastern Standard Time
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Millennial Potash releases Maiden Mineral Resource Estimate on Banio Potash Project
Millennial Potash Corp
Millenail Potash Corp Chairman Farhad Abasov joined Steve Darling from Proactive to share significant news regarding the company's Banio Potash Project in Gabon. Millennial Potash has released the results of its maiden Mineral Resource Estimate (MRE) for the northern part of the Banio Potash Project. The MRE incorporates new assay data from historic holes BA-002 and BA-003, along with assay results from additional potash cycles encountered during the drilling extension of BA-002, which was completed in September 2023. The MRE encompasses both Indicated and Inferred Mineral Resources. The Indicated Mineral Resources are estimated to be approximately 657 million tonnes, with a grade of 15.9% KCl, equating to 104.6 million tonnes of contained KCl. In contrast, the Inferred Mineral Resources are estimated to be approximately 1.159 billion tonnes, with a grade of 16.0% KCl, equating to 185.3 million tonnes of contained KCl. Abasov explained that this MRE forms a solid foundation for the upcoming Preliminary Economic Assessment (PEA). The PEA will explore various production scenarios utilizing solution mining and will likely include a proven processing route for the production of Muriate of Potash (MOP) directly on the Atlantic coast. These developments are significant milestones for Millennial Potash as the company advances its Banio Potash Project and further solidifies its position in the potash market. Contact Details Proactive Canada Proactive Canada +1 604-688-8158 action@proactiveinvestors.com
February 05, 2024 01:13 PM Eastern Standard Time
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Reunit Wallet Launches Reward Program: Trade To Earn
Reunit
Reunit Wallet, an omnichain wallet built on technology developed by LayerZero & Stargate Finance, is launching a volume-based reward program. In an effort to stimulate trading activity on its integrated platform and attract new users, Reunit Wallet is implementing a reward system for traders. Starting now, for every $100 in generated volume, users will receive 1 REUNI. Additionally, if a referral code is used, a 25% bonus will be applied. Users who share their referral code will also enjoy a 25% bonus on the rewards generated by the traders they've referred. Furthermore, Reunit Wallet has plans to soon introduce a staking feature for REUNI tokens. Participants in the staking program will receive 50% of the fees generated from transactions made through Reunit Wallet. Useful links Website: Twitter / X: About Reunit Wallet: Created by a former core-team member of Sushiswap (2020-2022), Reunit Wallet is the first natively omnichain wallet that enables seamless batch transfers across multiple blockchains with a single click. It also offers an integrated trading terminal supporting limit and market orders, providing a comprehensive and seamless trading experience. Security is a paramount priority for Reunit Wallet, which is why the wallet conducts a comprehensive simulation of each transaction and signature, allowing the user to anticipate the outcomes of their transaction, including token transfer confirmations or the granting of necessary permissions. Contact Details Reunit Wallet B.Naïm contact@everywhere.finance
February 05, 2024 01:07 PM Eastern Standard Time
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