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Successful Launch of HTX DAO and People's Exchange 2024: Justin Sun Aims to Build HTX as the People's Exchange

HTX DAO

Singapore, February 3, 2024 - The HTX DAO 2024 and People's Exchange Launch Ceremony took place in Singapore on February 2. The event marked the beginning of the HTX exchange's journey on decentralization and signaled the People's Exchange as its core ethos. At the event, Justin Sun, a core supporter of HTX DAO and member of HTX's Global Advisory Board, delivered a keynote speech, unmasking the first People's Exchange in the cryptocurrency space and highlighting the need for decentralization. He also shared his vision for HTX DAO and the exchange, along with the HTX DAO Governance Committee, ecosystem participants, and media outlets. HTX DAO: Empowering the Community Justin Sun pointed out that only a decentralized governance model can prevent tragedies like FTX and Mt. Gox from happening again and ensure the long-term security of users' assets while raising the asset ceiling, under the continuous growth of the industry. Moreover, only through decentralization can the blockchain and exchange industries reach a trillion-dollar level of asset scale. HTX DAO will lead the industry's evolution and create a new paradigm for protecting user assets in the exchange industry. It is reported that HTX DAO was officially established on January 18, with the aim of being a leading decentralized autonomous organization in the blockchain ecosystem and focusing on open finance and tokenized economy. The name of HTX DAO encapsulates its identity and strategic direction as a decentralized autonomous organization: The "H" symbolizes the HTX exchange, highlighting its noteworthy role within the HTX DAO ecosystem as the largest contributor to ecosystem liquidity. The "T" signifies the TRON blockchain, the technological foundation driving the HTX DAO ecosystem forward. The "X" embodies change and potential that blend in a multitude of beliefs at the heart of HTX DAO's vision. The "X" also stands as a symbol of the broad spectrum of reputable entities that will form the bedrock of this DAO ecosystem. Sun stated that HTX aims to transform into a decentralized, democratic, and autonomous exchange, which will be achieved through HTX DAO. This unique approach will empower $HTX holders to vote on listings, raise questions, and participate in decision-making and governance, propelling HTX towards decentralization. Ultimately, they will become the true owners of the platform. HTX DAO Gives the HTX Exchange a Second Life During the ceremony, Sun expressed that HTX DAO has given the HTX exchange a new lease of life. With a decentralized governance approach leading the next decade of development, HTX can operate sustainably for generations to come. As per Sun, with the support of HTX DAO and the HTX token, HTX will retain its centralized operational structure while embracing decentralized governance, branding, and decision-making, showcasing vitality and competitiveness as a democratic community. Sun also highlighted HTX DAO's strengths in community decision-making, governance, and operations. It will establish the HTX Senate, igniting active debate and decision-making regarding the development of HTX. With the principle of "From the Community, For the Community," HTX is poised to be a true people-centric exchange. It is worth noting that besides HTX, HTX DAO has attracted more builders for its ecosystem, including projects and institutions such as Ankr, Spark Digital Capital, Double Peak Capital, Zebec, Merkle 3s Capital, TRON, BitTorrent, JustLend DAO, Poloniex, Sun.io, Spark, Stratified Capital, stUSDT, APENFT, etc. At the same time, as co-builders, HTX, TRON, BitTorrent, and APENFT will contribute funds to support HTX DAO's liquidity, jointly promoting the development of HTX DAO. Summing up, Sun stated that HTX has gone through a decade as a centralized entity and hopes to accomplish its transformation to decentralization over the next decade, reaching long-term stability with a mechanism of complete democracy and transparency as a true People's Exchange. It is reported that this ceremony has garnered widespread attention from the HTX community and the cryptocurrency market. Web3 leading institutions attended the ceremony, such as Fireblocks, HashKey, Bithumb, and Paradigm, as well as media outlets like The Wall Street Journal, The Korea Times, FT Chinese, The Straits Times, Golden Finance, PANews, and others. About HTX DAO As a multi-chain deployed decentralized autonomous organization (DAO), HTX DAO demonstrates an innovative governance approach. Unlike traditional corporate structures, it adopts a decentralized governance structure composed of a diversified group, jointly committed to the success of this organization. This unique ecosystem advocates open values and encourages all DAO participants to propose collaborations and protocol enhancements that can promote the development of HTX DAO. Contact Details HTX DAO media@htxdao.com

February 03, 2024 03:05 AM Eastern Standard Time

Direxion Announces Exposure and Risk Increase on Single Stock Daily Leveraged ETFs

Direxion

Direxion has announced it will increase the leverage point and risk level of six single stock ETFs. The changes will heighten the risk of any investment in a Fund because they will result in an increase in the Fund's leverage. Currently, the six single stock ETFs seek daily leveraged investment results, before fees and expenses, of 150% of the daily performance of each ETF’s underlying security. (“1.5X”). Effective on or around April 2, 2024, each of the ETFs will seek daily leveraged investment results, before fees and expenses, of 200% of the daily performance of the ETF’s underlying security (“2X”). Further Fund-specific details, and associated risks, may be found by clicking the links in the table below. Because each Fund will seek to magnify the daily performance of its respective underlying security to a greater extent under its new investment objective, each Fund will have the potential for greater gains, but will also be subject to the risk of greater losses relative to the performance of each Fund's respective underlying security. All Direxion leveraged and inverse ETFs are intended only for investors with an in-depth understanding of the risks associated with seeking leveraged investment results, and who plan to actively monitor and manage their positions. There is no guarantee these ETFs will meet their objective. Please visit the Direxion Leveraged and Inverse ETF Education Center, where you will find educational brochures, videos, and a self-paced online course to help you understand if leveraged ETFs are right for you. About Direxion: Direxion equips investors who are driven by conviction with ETF solutions built for purpose and fine-tuned for precision. These solutions are available for a broad spectrum of investors, whether executing short-term tactical trades, or investing in thematic strategies. Direxion’s reputation is founded on developing products that precisely express market perspectives and allow investors to manage their risk exposure. Founded in 1997, the company has approximately $38.1 billion in assets under management as of December 31, 2023. For more information, please visit www.direxion.com. There is no guarantee that the Funds will achieve their investment objectives. For more information on all Direxion Shares ETFs, go to www.direxion.com, or call us at 866.301.9214. Leveraged and Inverse ETFs pursue daily leveraged investment objectives which means they are riskier than alternatives which do not use leverage. They seek daily goals and should not be expected to track the underlying index over periods longer than one day. They are not suitable for all investors and should be utilized only by sophisticated investors who understand leverage risk and who actively manage their investments. An investor should carefully consider a Fund’s investment objective, risks, charges, and expenses before investing. A Fund’s prospectus and summary prospectus contain this and other information about the Direxion Shares. To obtain a prospectus and summary prospectus call 866-476-7523 or visit our website at direxion.com. A Fund’s prospectus and summary prospectus should be read carefully before investing. Direxion Shares Risks - An investment in the ETFs involves risk, including the possible loss of principal. The ETFs are non-diversified and include risks associated with concentration that results from an ETF’s investments in a particular industry, sector or company, which can increase volatility. The use of derivatives such as futures contracts and swaps are subject to market risks that may cause their price to fluctuate over time. The ETFs do not attempt to, and should not be expected to, provide returns which are a multiple of respective underlying security for periods other than a single day. For other risks including leverage, correlation, daily compounding, market volatility and risks specific to an industry, sector or company, please read the prospectus. Please see the summary and full prospectuses for a more complete description of these and other risks of the Fund. Distributor: Foreside Fund Services, LLC. Contact Details Ditto Public Relations Danielle Black, SAE direxion@dittopr.co Company Website https://www.direxion.com/

February 02, 2024 04:47 PM Eastern Standard Time

Battery Mineral Resources Corp. Provides Punitaqui Update and Extends Closing Date on its Announced Offering of up to US$6M in Unsecured Convertible Debentures

Battery Mineral Resources Corp.

Battery Mineral Resources Corp. ( TSXV: BMR ) ( OTCQB: BTRMF ) (“ Battery ” or “ BMR ” or the “ Company ”) is pleased to provide project updates and also announce an extension to the final closing date of its private placement (the “ Private Placement ”) of up to US$6,000,000 in senior unsecured convertible debentures (the “ Debentures ”), which was previously announced on October 17, 2023. Operational Readiness The Company is pleased to announce that effective January 26, 2024, it has received an exploitation permit from Chile's National Geology and Mining Service (SERNAGEOMIN) with regards to the Cinabrio mine, which forms part of the Punitaqui mining complex. The Cinabrio mine is the original mine which supported copper concentrate production during the approximately 10 years of historic copper production, primarily operated by Glencore PLC. The exploitation permit allows BMR to extract copper ore and barren rock from the Cinabrio mine as the mine is being prepared for resumption of full production. The Company anticipates commencing pre-production maintenance activities at Cinabrio in the very near-term, including rehabilitation of existing workings, drifting and establishment of access for drilling and exploitation – all of which allows for the resumption of ore extraction. As previously announced, an exploitation permit for the San Andres mine has been granted. The permit allows for BMR to commence drifting, ramp construction and mine development on two different elevation levels and allows for establishment of new underground exploration drilling platforms. This mine development will establish access to new zones of copper mineralization for the forthcoming mine production. Mining equipment and supplies to support these activities has been delivered and personnel recruitment is progressing well. Repairs, replacements and upgrades of the crushing, grinding and flotation plant are progressing well, and operational commissioning of the facility is expected to begin in the latter part of Q1, 2024, followed by copper concentrate production in Q2, 2024. Private Placement The TSX Venture Exchange (the “ TSXV ”) has approved an extension to the Private Placement to February 14, 2024. The proceeds from the Debentures will be applied towards working capital and the restart of copper concentrate production at the Company’s Punitaqui mining complex in Chile (the “ Restart ”). The Company continues to progress towards securing the balance of the capital required for the Restart and, to date, has successfully raised US$3,285,000 (C$4,407,484) in Debentures. The Company estimates the total capital required for the Restart to be approximately US$13 million (approximately C$17.4 million) (prior to corporate costs and other asset holding costs and inclusive of amounts to be raised in the Private Placement). The Company looks forward to providing additional updates to the market in the coming weeks as Punitaqui is propelled back into sustainable, profitable production for all stakeholders. Offering Terms (as previously disclosed) The Debentures will mature on September 30, 2026 (the “ Maturity Date ”) and will bear interest at 10% per annum, compounding annually on September 30 of each year, not in advance. Interest accrued from the date of issuance up to and including March 30, 2025, will be paid by way of issuance of common shares of the Company. Interest accrued following March 30, 2025, will be, at the option of the holder, paid either in cash or by way of issuance of common shares of the Company. The issuance of common shares as payment of interest will be at the then current market price of the Company’s common shares at the date the interest becomes payable and will be subject to the prior acceptance of the TSXV and applicable securities laws. The holder of a Debenture may, at their option, at any time from March 31, 2024, and prior to the close of business on the business day immediately preceding the Maturity Date, convert all, but not less than all, of the principal amount of such Debenture into common shares of the Company at the conversion price of US$0.22 per share (approximately C$0.30 per share). All Debentures issued in the Private Placement are subject to a four month hold period under applicable Canadian securities laws and under the policies of the TSXV. The Private Placement is subject to final approval by the TSXV. Exchange Rates All USD amounts for which CAD equivalent amounts are given in this news release were calculated at CAD/USD exchange rate of 1.3417, the exchange rate published by the Bank of Canada on January 30, 2024. MI 61-101 Matters Weston Energy LLC and Weston Energy II LLC are “related parties” to BMR pursuant to pursuant to Multilateral Instrument 61-101 – Protection of Minority Security Holders in Special Transactions (“ MI 61-101 “). Prior to giving effect to the transactions disclosed in this news release and in the refinancing transactions disclosed in the Company’s press release dated October 17, 2023, Weston Energy LLC and Weston Energy II LLC and its affiliates owned or controlled (directly or indirectly) 107,578,740 BMR Common Shares on an undiluted basis and 122,491,305 BMR Common Shares assuming the conversion of all the Company’s previously outstanding secured convertible debentures (representing approximately 60.60% and 63.31%, respectively, of the outstanding BMR Common Shares). Disclaimers The Debentures (including any issued in future closings) will be sold in a transaction exempt from registration under the Securities Act of 1933, as amended (the “ Securities Act ”) and will be sold only to persons reasonably believed to be accredited investors in the United States under Rule 506 under the Securities Act and outside the United States only to non-U.S. persons in accordance with Regulation S under the Securities Act. The Debentures and the shares of common stock issuable upon conversion of the Debentures, if any, have not been and will not be registered under the Securities Act, or any state securities laws, and unless so registered, may not be offered or sold in the United States except pursuant to an applicable exemption from such registration requirements of the Securities Act and applicable state securities laws. This press release does not constitute an offer to sell or a solicitation of an offer to buy any of the Debentures or any shares of common stock potentially issuable upon conversion of the Debentures nor shall there be any sale of Debentures (or shares issuable upon conversion thereof) in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such state. There can be no assurance that any future offerings of Debentures will be completed. About Battery Mineral Resources Corp. Battery Mineral Resources is a battery minerals company providing shareholders exposure to the global mega-trend of electrification while being focused on growth through cash-flow, exploration, and acquisitions in favourable mining jurisdictions. Battery Mineral’s mission is the discovery, acquisition, and development of battery metals (namely cobalt, lithium, graphite, and copper), in North America, South America and South Korea and to become a premier and responsible supplier of battery minerals to the electrification marketplace. BMR is currently pursuing a near-term resumption of operations of the Punitaqui Mining Complex, a past copper-gold-silver producer, in the Coquimbo region of Chile. BMR is the largest mineral claim holder in the historic Gowganda Cobalt-Silver Camp in Ontario, Canada, and continues to pursue a focused program to build on the recently announced, +1-million-pound high-grade cobalt resource at McAra. In addition, Battery Mineral owns 100% of ESI Energy Services, Inc. (including ESI’s wholly owned USA operating subsidiary, Ozzie’s, Inc.), a profitable mainline pipeline and renewable energy equipment rental and sales company with operations in Alberta, Canada and Arizona, USA. Battery Mineral Resources is based in Canada and its shares are listed on the Toronto Venture Exchange under the symbol “BMR” and on the OTCQB under the symbol “BTRMF”. Further information about BMR and its projects can be found on www.bmrcorp.com. Neither the TSXV nor its Regulation Services Provider (as that term is defined in the policies of the TSXV) accepts responsibility for the adequacy or accuracy of this press release. Forward Looking Statements This news release includes certain “forward-looking statements” under applicable securities laws. There can be no assurance that such statements will prove to be accurate, and actual results and future events could differ materially from those anticipated in such statements. Forward-looking statements reflect the beliefs, opinions and projections of the Company on the date the statements are made and are based upon a number of assumptions and estimates that, while considered reasonable by the Company, are inherently subject to significant business, economic, competitive, political and social uncertainties and contingencies. Many factors, both known and unknown, could cause actual results, performance, or achievements to be materially different from the results, performance or achievements that are or may be expressed or implied by such forward-looking statements and the parties have made assumptions and estimates based on or related to many of these factors. Such factors include, without limitation, the ability of the Company to obtain sufficient financing (including through the Private Placement) to complete exploration and development activities, the ability of the Company to close further tranches of the Private Placement, the completion, timing and size of the proposed Private Placement, the intended use of the proceeds of the Private Placement, risks related to share price and market conditions, the inherent risks involved in the mining, exploration and development of mineral properties, the ability of the Company to meet its anticipated development schedule, government regulation and fluctuating metal prices. Accordingly, readers should not place undue reliance on forward-looking statements. Battery undertakes no obligation to update publicly or otherwise revise any forward-looking statements contained herein, whether as a result of new information or future events or otherwise, except as may be required by law. For further information regarding the risks please refer to the risk factors discussed in Battery’s most recent Management Discussion and Analysis filed on SEDAR+. Contact Details Battery Mineral Resources Corp. Martin Kostuik, CEO +1 604-229-3830 info@bmrcorp.com Corporate Communications, IBN (InvestorBrandNetwork) +1 310-299-1717 editor@investorbrandnetwork.com Company Website https://bmrcorp.com/

February 02, 2024 01:05 PM Pacific Standard Time

Lindsay Rosenwald’s Fortress Bio (NASDAQ: FBIO) Spotlight on 2024 Milestones from Subsidiaries

Fortress Biotech, Inc.

New York, Feb 2, 2024 - ( Plato Data via 500NewsWire) -- Fortress Biotech (Fortress Bio), a unique biotech company led by industry veteran Dr. Lindsay Rosenwald, focused on identifying, in-licensing and developing high-potential marketed drugs and development-stage drug candidates in-house and through its subsidiary partner companies, has announced multiple new milestones to start 2024 with a bang. Avenue Therapeutics Finalizes Phase 3 Study for IV Tramadol with FDA Avenue Therapeutics, a subsidiary of Fortress Bio, has reached a significant milestone in its quest to introduce new therapies for neurologic diseases. The company has finalized an agreement with the U.S. Food and Drug Administration (FDA) on a Phase 3 safety study for intravenous (IV) tramadol. This drug, currently in development, is aimed at treating acute post-operative pain in medically supervised settings. The pivotal non-inferiority study will assess the risk of opioid-induced respiratory depression linked to opioid stacking in IV tramadol compared to IV morphine. The study will involve around 300 patients undergoing bunionectomy, comparing the effects of IV tramadol to IV morphine over a 48-hour post-operative period. This study follows the success of IV tramadol in two previous Phase 3 efficacy trials. Avenue Therapeutics' CEO, Dr. Alexandra MacLean, expressed optimism about the trial, noting the collaborative efforts with the FDA and the potential of IV tramadol in managing acute post-operative pain safely. The trial's success could lead to FDA approval of IV tramadol, offering a new pain management option for patients in the United States. Journey Medical Corporation Submits NDA for DFD-29 to Treat Rosacea I n another significant development, Journey Medical Corporation, also a Fortress Biotech subsidiary, has submitted a New Drug Application (NDA) to the FDA for DFD-29. This drug, designed for the treatment of rosacea, could revolutionize the approach to this skin condition. DFD-29, or Minocycline Hydrochloride Modified Release Capsules (40 mg), aims to treat both inflammatory lesions and erythema (redness) associated with rosacea. This submission follows the success of two Phase 3 clinical trials, which met all primary and secondary endpoints without significant safety issues. Claude Maraoui, Co-Founder, President, and CEO of Journey Medical, highlighted the potential of DFD-29 as a best-in-class oral treatment for rosacea, noting its superiority over existing treatments and placebo in clinical trials. The drug's approval could benefit the approximately 16 million Americans suffering from rosacea, providing a comprehensive treatment option for both inflammatory lesions and erythema. Conclusion These developments from Avenue Therapeutics and Journey Medical Corporation, subsidiaries of Fortress Bio, mark the start of an exciting year for the company. The progress in the development of IV tramadol and DFD-29 showcases Fortress Bio's commitment to advancing medical treatments and enhancing patient care. These milestones reflect the company's strategic direction and potential in 2024, potentially offering hope for new, effective treatment options in neurology and dermatology. Source: Plato Data Intelligence Contact Details Amplifi PR -Bryan Feinberg, CEO +1 551-574-2169 Zephyr@platodata.io

February 02, 2024 02:40 PM Eastern Standard Time

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Heart of Florida United Way's Digital Transformation Empowers Community Impact

Avenue Z

Avenue Z, a strategic communications and marketing company, and Zillas, a top digital marketing agency in Orlando, are thrilled to announce Heart of Florida United Way's ( HFUW ) digital transformation with the launch of their new website. This transformative project underscores HFUW's dedication to serving the Central Florida community while aligning perfectly with Avenue Z’s mission of leveraging strategic communication and digital marketing to build brand reputations, foster relationships, and enhance return on investment. At the core of HFUW's mission is the belief in the power of collective action to bring about positive change in the community. The organization is steadfast in addressing the most pressing challenges facing Central Florida by uniting individuals, groups, and institutions to strategically and efficiently tackle these issues. Key Highlights of the Digital Transformation: 1. Community-Centric Design: The meticulously crafted website not only embodies HFUW's mission but also prioritizes the Central Florida community's needs in reaching digitally marginalized audiences. The user-centric design ensures seamless navigation, enabling visitors to easily access vital services and support, regardless of device or digital savvy. 2. Enhanced Accessibility: The redesigned website places a strong emphasis on accessibility, catering to diverse demographics, including seniors and younger audiences. Features such as clear fonts, large buttons, and responsive design ensure an inclusive user experience. 3. User Journey Content Alignment: HFUW had a wealth of existing content: inspiring stories, multilingual information, and helpful resources — all of which needed to be more visible to communicate the organization's impact and ways they can help. The website now features three key action items: procuring donations, recruiting volunteers, and providing help. After the redesign, the website is also better positioned to showcase HFUW's diverse programs and initiatives, inspiring community members to actively participate in driving positive change. 4. Streamlined Resource Access: The website provides corporate partners, volunteers, and individuals with effortless access to information about the many ways they can engage with HFUW, effectively reducing barriers to community engagement and support. Dani Moritz, Director of Marketing and Communications at HFUW, expressed her excitement about the project, stating, " Avenue Z has not only rejuvenated our website — making it more visually appealing than ever before — but has also helped us effectively communicate our unwavering commitment to the Central Florida community. This digital transformation empowers us to better serve our community and make a lasting impact. " Karlye Martorelli, Business Engagement Manager at HFUW commented on the impact this transformation will have on the population HFUW serves, which spans generations. “ We are working to inspire youth to take on STEM careers and more modern concepts. We want to reach younger generations and need our website to reflect that. I love the new design because it really does accomplish that, but it’s also user-friendly for seniors to navigate, as well. ” Avenue Z is immensely proud to have played a central role in advancing HFUW's mission to create enduring solutions that enhance the well-being of Central Florida residents. According to their 2021-2022 Annual Report, HFUW’s impact generated: $50 million invested into the community 703,000 people served 411,000 community members supported with basic needs 27,000 hours served by volunteers This digital transformation marks a significant milestone in HFUW's journey toward a stronger, more connected community, and should provide a measurable increase in impact performance. “ We are thrilled at the end result of partnering with Avenue Z on HFUW’s new website, ” said Jeff Hayward, President and CEO at HFUW. “ The design modernizes our brand and, most importantly, more effectively communicates who we are and what we do. My hope is that this digital marketing development helps us better communicate to a wider audience — so that we can work hand-in-hand with individuals and organizations across Central Florida to solve our community’s most pressing challenges. ” " As a proud supporter of Heart of Florida United Way, we are thrilled to have been a part of this transformative project. The redesigned website reflects our shared mission to create enduring solutions and enhance the well-being of Central Florida residents. Together, we are changing lives and making a significant difference, ” said Johnny Hughes, Chief Digital Officer at Avenue Z. Avenue Z also recently partnered with Heart of Florida United Way on their Change Maker Impact Awards. These awards recognize the individuals and groups who are making significant contributions to the Central Florida community. This year, Avenue Z was pleased to present the Women United Impact Award to Mia Poinsette of The Poinsette Foundation, for her work in uplifting children and families in Central Florida. Guided by disruptive philanthropy, her mission is to ‘serve the underestimated,’ addressing gaps in service and fulfilling immediate needs for women and children of color with over 80 partners and $100k reinvested in the local community, to date. About Heart of Florida United Way: Heart of Florida United Way (HFUW) stands up for the education, financial stability, health, and basic needs of every person in Central Florida. Since 1939, HFUW has delivered programs, invested dollars, and convened community members around important issues impacting Orange, Seminole, and Osceola counties. As Central Florida’s most comprehensive health and human services nonprofit, HFUW created a $50 million impact in Central Florida last year. In 2021-22, HFUW served more than 703,000 people through its direct service and funded programs. HFUW is home to notable community resources like the 211 Information & Referral Crisis Line; 988 Suicide Prevention Lifeline; Mission United program for Veterans; TECHquity, an initiative bridging the digital divide; Destination Graduation at Seminole State College; the Ryan White Part B & General Revenue program, which administers nearly $2.3 million to provide HIV/AIDS services and referrals; the Planning Council Support program that facilitates community planning and priority setting for HIV services. United Way partners with individuals, local businesses, government, and other nonprofit agencies to open opportunities and close gaps in Central Florida. Visit www.HFUW.org for more information, or call (407) 835-0900. Avenue Z is a leading strategic communications and digital marketing company specializing in convergence marketing - uniting communications, media, creative, and proprietary analytics to transform public perception and accelerate growth. With offices nationwide, Avenue Z grows companies, causes, challengers, and changemakers to capitalize on the future with an unfair advantage: our converged capabilities and platforms. Visit: www.AvenueZ.com. Contact Details Avenue Z Press Inquiries press@avenuez.com Company Website https://www.avenuez.com/

February 02, 2024 08:45 AM Eastern Standard Time

2 Million Cancer Diagnoses And 600,000 Cancer Deaths Expected In 2024 – Prevention Is Key To Treatment, And Mainz Biomed Is Leading The Charge

Benzinga

By Faith Ashmore, Benzinga The global population is experiencing a scary increase in colorectal cancer, especially among young people. Colorectal cancer (CRC) diagnoses have been steadily rising since the 1990s; in 1995 the proportion of these cancer cases in adults younger than 55 was 11%, and in 2019, the number was 20%. It is recommended that adults start screening for colorectal cancer at age 45 but with the increase in prevalence, the value of early detection cannot be understated. While doctors still aren’t sure of the reason behind this increase, they are urging the public to take these numbers seriously and embrace preventative measures for early detection. Companies like Mainz Biomed (NASDAQ: MYNZ), a company that specializes in developing molecular genetic diagnostic solutions for life-threatening conditions, are leading the charge in helping make that happen. This company has created ColoAlert®, an innovative product that addresses the need for easier and more accessible cancer screenings for quick detection and treatment of colorectal cancer. The non-invasive and user-friendly test aims to make colorectal cancer screening fast, simple and precise. Once launched in the U.S. Mainz Biomed's ColoAlert will compete with Cologuard from Exact Sciences Corporation (NASDAQ: EXAS), a well-established company that commands a market cap of over $10 billion. The key difference between Cologuard and ColoAlert is that ColoAlert requires far less stool collection than its competitor, a testament to ColoAlert’s technology. This not only increases convenience for the patient but also cuts down on shipping costs and lab time. The only other detection model outside of a traditional colonoscopy is a blood-stool test; however, these tests can only detect cancer, not pre-cancerous polyps. Mainz Biomed has partnered with Liquid Biosciences to ensure its cutting-edge products are top-of-the-line. Recently, Mainz Biomed conducted a multi-center international clinical trial in Germany and Norway to evaluate the effectiveness of incorporating mRNA biomarkers into ColoAlert®. The study yielded impressive findings, demonstrating a high sensitivity of 94.4% and specificity of 97.5% for detecting CRC. Additionally, the screening test showed a sensitivity of 80% and specificity of 95.2% in detecting precursor lesions, including advanced adenomas that may develop into CRC. In other words, ColoAlert is designed to detect pre-cancerous polyps as well as identify individuals who have colorectal cancer. The CDC reports that colorectal cancer is the second most fatal cancer in the United States and Europe. However, it is also the most preventable, with early detection leading to survival rates above 90%. ColoAlert can be instrumental in preventive care for colorectal cancer. The company reports it has experienced success in Germany, where the product is available through labs, industry partnerships and online for purchase. In 2024, Mainz Biomed is looking to replicate this success in the U.S. and is planning to launch a pivotal trial, seeking FDA approval for its product. If successful, the company will look to partner with a network of labs across the country to increase accessibility to its product with the hope that more Americans will be able to detect pre-cancerous polyps before it is too late. With the American Cancer Society predicting over 600,000 cancer deaths and the equivalent of 5,000 cancer diagnoses each day in 2024, prevention is key to treatment. The preventive healthcare market has gotten a lot of attention in recent years, and it is expected to reach $415 billion by 2031 with a CAGR of 9.7% from 2024 to 2031. Mainz Biomed’s ColoAlert is a great example of the power of technology that can screen for pre-cancerous markers. Mainz Biomed's dedication to pushing the limits of diagnostic technology, enhancing accessibility and its growth trajectory potentially establish it as a formidable presence in the industry, setting it apart from its competitors. Featured photo by Artur Tumasjan on Unsplash. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

February 02, 2024 08:35 AM Eastern Standard Time

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Bitget Wallet Now Supports Berachain Artio Testnet

Bitget

Bitget Wallet, the leading Web3 trading wallet, has recently integrated with Berachain Artio Testnet, an EVM-compatible Layer 1 blockchain. Bitget Wallet users may now seamlessly add the testnet on both their app and browser extension wallets, which will allow them to enjoy convenient on-chain asset management, transfers, interaction with ecosystem DApps, and the acquisition of BERA test tokens. Trending DApps on the Berachain ecosystem will also be featured on Bitget Wallet's DApp browser to facilitate ease of discovery and accessibility. Berachain is a high-performance, EVM-compatible blockchain built on Proof-of-Liquidity consensus. The network rearchitects the traditional smart contract platform to a novel, Cosmos-native configuration. Users provide liquidity into the chain-enshrined primitives (dex, perps, stable lend, or others voted in by governance) to earn BGT, delegate it with validators to earn fees/bribes, or burn it into Bera. Through their contribution to liquidity on the chain, users bootstrap its security. As Berachain gears up for its impending mainnet launch slated for the second quarter of this year, Bitget Wallet remains committed to its goal of providing close support for the ecosystem and being the first to deliver seamless access for all Bitget Wallet users. Additionally, the Bitget Wallet team has announced a collaboration with Berachain to initiate an incentive campaign for the testnet ecosystem next month, aimed at enhancing user engagement on the Berachain Testnet. With a growing global user base of over 15 million, Bitget Wallet supports an impressive array of over 100 mainnets. Its custom network functionality enables the integration of hundreds of EVM-compatible chains, broadening users' access to the expansive Web3 ecosystem and accelerating the discovery of novel assets and emerging opportunities in the industry. About Bitget Wallet Bitget Wallet stands as Asia's largest and global frontrunner among all-in-one Web3 multi-chain wallets. We offer a comprehensive range of on-chain products and DeFi services to our users, including wallet functionality, Swap feature, NFT trading, DApp browsing, and more. With a 5-year legacy, Bitget Wallet has garnered acclaim from over 15 million users worldwide and has secured partnerships with prominent industry leaders including Bitcoin, Ethereum, TRON, BNB Chain, Solana, Base, and others. This success stems from our commitment to consistently delivering secure and convenient products and services. For more information, visit: Website | Twitter | Telegram | Discord Contact Details Bitget Rachel Cheung media@bitget.com Company Website https://www.bitget.com/

February 02, 2024 06:58 AM Eastern Standard Time

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Industrials ETF 'XLI': Potential Catalyst for Growth and Expansion

Select Sector SPDR

The industrial sector, traditionally the backbone of any robust economy, is currently experiencing a resurgence. As a nation, we are focusing on revitalizing our infrastructure, which includes railroads, aviation, and heavy machinery. This renewed focus has increased demand for industrial space and sparked job creation in these sectors. An exchange-traded fund (ETF) such as the Industrials Select Sector SPDR Fund (XLI) provides investors with an efficient, cost-effective* way to gain exposure to this expanding sector. XLI offers access to key sub-sectors of the US economy which may fuel this growth. The XLI tracks a market cap-weighted index of industrial-sector stocks drawn from the S&P 500. Currently holding over $15 billion in assets under management, it has a low annual expense ratio of 0.10%, making it one of the most efficient and tradable ways to gain access to the industrial sector. The top 10 holdings** for XLI are: Caterpillar Inc. (4.28%) Union Pacific Corp. (4.25%) Boeing Co. (4.20%) General Electric Co. (3.94%) Honeywell International Inc. (3.92%) Uber Technologies (3.59%) RTX (3.43%) United Parcel Service, Inc. Class B (3.22%) Deere & Co. (3.04%) Lockheed Martin Corp. (2.84%) Dominant Market Players Caterpillar Inc., Union Pacific Corp., Boeing Co., General Electric Co., Honeywell International Inc., and Uber Technologies dominate the sector by market capitalization, representing industries such as aerospace and defense, building products, construction and engineering, electrical equipment, conglomerates, machinery, commercial services and supplies, air freight and logistics, airlines, marine, road, and rail. Investors ranging from institutional, broker-dealers, financial advisors, and retail are adding diversification to their portfolios with XLI. This actively traded ETF can be an attractive option for investors and traders seeking exposure to the sector. The foundation of any strong economy lies in the manufacturing and distribution of goods to businesses and consumers. XLI provides investors with exposure to this fundamental process that is essential to the daily operations of commerce, retail, and services. The Role of XLI in Portfolio Diversification A key aspect of building a portfolio is understanding the significance of each of the core 11 sectors of the S&P 500. The industrial sector, represented by XLI, can serve as a viable starting point for investors of all sizes seeking diversified investments. As we move forward, XLI can open doors to manufacturing and transportation, serving as a gateway to the infrastructure revitalization and industrial expansion that is currently driving our economy. DISCLAIMER: This is a work of research and should not be taken as investment or financial advice. Therefore, Select Sector SPDRs or the publisher is not liable for any decision made based on the publication. About the Company: Select Sector SPDR ETFs offer flexibility and customization opportunities. Many investors have similar outlooks, but no two are exactly alike. Select Sector SPDR ETFs let investors select the sectors that best meet their investment goals. *Ordinary brokerage fees apply **Holdings, Weightings & Assets as of 12/31/23 subject to change DISCLOSURES The S&P 500 Index is an unmanaged index of 500 common stocks that is generally considered representative of the U.S. stock market. The index is heavily weighted toward stocks with large market capitalizations and represents approximately two-thirds of the total market value of all domestic common stocks. The S&P 500 Index figures do not reflect any fees, expenses or taxes. An investor should consider investment objectives, risks, fees and expenses before investing. One may not invest directly in an index. Transparent ETFs provide daily disclosure of portfolio holdings and weightings All ETFs are subject to risk, including loss of principal. Sector ETF products are also subject to sector risk and nondiversification risk, which generally will result in greater price fluctuations than the overall market. Diversification does not eliminate risk. An investor should consider investment objectives, risks, charges and expenses carefully before investing. To obtain a prospectus, which contains this and other information, call 1-866-SECTOR-ETF (732-8673) or visit www.sectorspdrs.com. Read the prospectus carefully before investing. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is distributor for the Select Sector SPDR Trust. Media Contact: Company: Select Sector SPDRs Contact: Dan Dolan* Address: 1290 Broadway, Suite 1000, Denver, CO 80203 Country: United States Email: dan.dolan@sectorspdrs.com Website: https://www.sectorspdrs.com/ *Dan Dolan is a Registered Representative of ALPS Portfolio Solutions Distributor, Inc. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is the distributor for the Select Sector SPDR Trust. SEL007228 EXP 3/31/24 Contact Details Dan Dolan +1 203-935-8103 dan.dolan@sectorspdrs.com Company Website https://www.sectorspdrs.com/

February 02, 2024 05:00 AM Eastern Standard Time

News Release

Tisdale Clean Energy Upsizes Private Placement and Closes $1.145M Second Tranche

Tisdale Clean Energy Corp.

Vancouver, B.C. – TheNewswire - February 1, 2024 – TISDALE CLEAN ENERGY CORP. (the “ Company ” or “ Tisdale ”) (CSE:TCEC ), ( OTC:TCEFF ), ( FSE:T1KC ), is pleased to announce that it has closed a second tranche of its non-brokered private placement (the “ Offering ”) and has issued a further 6,362,216 units (each, a “ Unit ”) at a price of $0.18 per Unit for gross proceeds of $1,145,199. Each “Unit” issued in the second tranche of the Offering consists of one common share of the Company and one share purchase warrant exercisable at a price of $0.30 until February 1, 2026. In connection with completion of the second tranche of the Offering, the Company paid $17,500 and issued 97,222 share purchase warrants (each, a “ Brokers Warrant ”) to certain arms-length brokerage firms who assisted in introducing subscribers to the Offering. Each Brokers Warrant is exercisable at a price of $0.30 until February 1, 2026. All securities issued in connection with the second tranche of the Offering are subject to restrictions on resale until June 2, 2024, in accordance with applicable securities laws. When combined with the first tranche of the Offering, the Company has raised gross proceeds of $1,920,199 through the issuance of 10,667,772 Units. Due to strong market interest, the Company has elected to increase the size of the Offering by 5,405,405 Units for a total of 16,666,667 Units, which if fully subscribed would increase total gross proceeds to $3,000,000. The Company anticipates completing the final tranche of the Offering in the next two weeks. Completion of a final tranche of the Offering remains subject to any required regulatory approvals. The proceeds from the Offering will be used for general working capital purposes and for carrying out exploration programs at the South Falcon East uranium project. About Tisdale Clean Energy Corp. Tisdale Clean Energy is a Canadian-based uranium exploration and development company. The Company is currently developing the South Falcon East uranium project, a 12,770-hectare project located in the Athabasca Basin region, Saskatchewan, Canada, which contains the Fraser Lakes B uranium/thorium deposit. For further information, contact Alex Klenman at info@tisdalecleanenergy.com or 604.970.4330. ON BEHALF OF THE BOARD OF TISDALE CLEAN ENERGY CORP. “Alex Klenman” Alex Klenman, Chief Executive Officer This news release may contain certain “Forward-Looking Statements” within the meaning of the United States Private Securities Litigation Reform Act of 1995 and applicable Canadian securities laws. When or if used in this news release, the words “anticipate”, “believe”, “estimate”, “expect”, “target, “plan”, “forecast”, “may”, “schedule” and similar words or expressions identify forward-looking statements or information. These forward-looking statements or information may relate to the anticipated use of proceeds from the Offering and other factors or information. Such statements represent the Company’s current views with respect to future events and are necessarily based upon a number of assumptions and estimates that, while considered reasonable by the Company, are inherently subject to significant business, economic, competitive, political and social risks, contingencies and uncertainties. Many factors, both known and unknown, could cause results, performance or achievements to be materially different from the results, performance or achievements that are or may be expressed or implied by such forward-looking statements. The Company does not intend, and does not assume any obligation, to update these forward-looking statements or information to reflect changes in assumptions or changes in circumstances or any other events affecting such statements and information other than as required by applicable laws, rules and regulations.

February 01, 2024 03:15 PM Eastern Standard Time

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Industrials ETF 'XLI': Potential Catalyst for Growth and Expansion

Tisdale Clean Energy Upsizes Private Placement and Closes $1.145M Second Tranche