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Comcast Unveils Xfinity Rewards Hot Air Balloon in Clovis

Comcast California

Comcast is proud to announce its participation in the 49th annual ClovisFest & Hot Air Balloon Fun Fly, taking place from September 28-29, 2024, in Clovis, California. Comcast will bring its Xfinity Rewards branded hot air balloon to California for the first time at the iconic Central Valley event, offering attendees a unique and immersive experience. Come check out the balloon before everyone else at the ClovisFest & Hot Air Balloon Fun Fly Media Day. During the media day, journalists will have the opportunity to interview the balloon’s pilot, Comcast executives and Fresno’s local celebrity, Chantea McIntyre, who will fly in the balloon. Chantea is a content creator and first runner up to Miss California USA 2024. WHAT: Capture breathtaking images of the 85-feet-high Xfinity Rewards branded hot air balloon as it flies for the first time in California, making its debut at the ClovisFest & Hot Air Balloon Fun Fly Media Day. There will be seven other hot air balloons on display. WHEN: Friday, September 27, 2024. Doors open at 6:00 AM and balloons begin flying at approximately 6:15 AM, weather permitting. WHO: Chantea McIntyre, content creator and first runner-up to Miss California USA 2024 Justin Minniti, Area Vice President for the South Valley at Comcast Jacob Little, Xfinity Rewards hot air balloon pilot Greg Newman, President and CEO for the Clovis Chamber of Commerce WHERE: Clovis Rodeo Fairgrounds - 748 Rodeo Dr, Clovis, CA 93612 About Comcast Corporation Comcast Corporation (Nasdaq: CMCSA) is a global media and technology company that connects people to moments that matter. We are principally focused on connectivity, aggregation, and streaming with 57 million customer relationships across the United States and Europe. We deliver broadband, wireless, and video through our Xfinity, Comcast Business, and Sky brands; create, distribute, and stream leading entertainment, sports, and news through Universal Filmed Entertainment Group, Universal Studio Group, Sky Studios, the NBC and Telemundo broadcast networks, multiple cable networks, Peacock, NBCUniversal News Group, NBC Sports, Sky News, and Sky Sports; and provide memorable experiences at Universal Parks and Resorts in the United States and Asia. Visit www.comcastcorporation.com for more information. Contact Details Adriana Arvizo +1 925-200-1919 Adriana_Arvizo@comcast.com Company Website https://california.comcast.com/

September 26, 2024 10:00 AM Pacific Daylight Time

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Men's Telehealth Company's Plans To Change Men's Wellness

Benzinga

By Johnny Rice, Benzinga Jacob Cohen, CEO of MangoRX (NASDAQ: MGRX), was recently a guest on Benzinga’s All-Access. MangoRX is focused on developing a variety of men's health and wellness products and services via a secure telemedicine platform. The company specializes in proprietary products and compounded medicines that elevate men’s ability to perform in all aspects of life. The company has several new products that it is in the process of developing and releasing in global markets from the U.S. to China. Learn more here: Featured photo by Brooke Cagle on Unsplash. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

September 26, 2024 08:30 AM Eastern Daylight Time

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Former USC Student-Athlete L Simpson Launches "Take No L’s" Collection with Shiekh at USC Village

Full Scope PR

Current USC student, former USC football player and fashion entrepreneur L Simpson is rewriting the playbook for student-athletes with the exclusive launch of his highly anticipated streetwear collection, “Take No L’s”, at Shiekh at USC Village on Sept. 26. What began as a middle school project has evolved into a brand that embodies a mindset of relentless determination: no losses, only lessons – whether it’s on the court, field or in life. “Take No L’s” gained significant traction throughout Simpson’s high school basketball career at Sierra Canyon High School (Chatsworth, Calif.), where he captained his team to back-to-back California Open State Championships alongside notable teammates Scottie Pippen Jr., KJ Martin, Cassius Stanley and Christian Koloko. The brand’s momentum continued to increase when he joined USC’s renowned football program. Coached by USC head coach Lincoln Riley alongside former teammates and current NFL players, Caleb Williams, Jordan Addison and Brenden Rice, “Take No L’s” quickly became a regularly worn brand among his teammates and coaches. “I’m thrilled for L,” said USC head coach Lincoln Riley. “It’s always great to watch our players achieve their dreams, both on and off of the field. Whether we’re on campus or around the city, our players and staff love wearing the brand. L is extremely bright and innovate, and I know he is going to be incredibly successful.” “This launch is special,” says Simpson. “I shopped at Shiekh as a kid. Whenever Jordans would drop or when I wanted new athletic gear, I would always ask my parents to take me to Shiekh. It truly does feel like a full- circle moment. We’re not just selling clothes; we’re promoting a mindset of going after your dreams and never accepting defeat. That’s what Take No L’s stands for—no losses, just lessons.” Take No L’s is a bold, confident and unapologetic premium streetwear brand featuring striking graphics and vibrant colors. The collection includes hoodies, cropped sweatshirts, t-shirts, sweatpants and hats, with prices ranging from $90 to $200. With significant attention from L’s influencer network, which boasts a combined reach of over 100 million followers, the brand is already generating buzz on social media. Join Simpson on Sept. 26 from 3 p.m. to 6 p.m. PT at Shiekh in USC Village for the official launch of the “Take No L’s” collection. Experience firsthand why “Take No L’s” is setting a new standard in streetwear. The event will include special appearances, exclusive products and live entertainment featuring stars like Storm Reid, Brenden Rice, Riri Simpson, Jazz Hill, Temi Ojoro, Tade Ojoro, Ceyair Wright, Amber Jasmine, Lboogz, and Saint Thomas. Don't miss this exciting celebration of fashion and culture! About L Simpson: L Simpson, current USC student and former student-athlete, is the founder of the “Take No L’s” brand. Inspired by sports, culture and the journey of perseverance, Simpson created “Take No L’s” to encourage people to live fearlessly and embrace a lifestyle without losses. Simpson’s collection combines bold design, high-quality fabrics and empowering messaging to create a distinctive streetwear line that resonates with today’s generation. L has previously hosted his own talk show on SLAM and recently co-hosted the “Almost Pro” podcast with former Heisman Trophy winner Caleb Williams. Simpson is currently pursuing a degree in communication from the USC Annenberg School of Communication and Journalism, and he will graduate in the spring of 2025. For more info on the brand, visit takenolsstore.com and follow Simpson on Instagram at @lboogz. About Shiekh Shoes: Style Elevated, Sneakers Celebrated. Shiekh offers a curated collection of footwear, apparel, and accessories. Explore top brands like Nike, Adidas, and Jordan at Shiekh. Shiekh stores can be found at premium locations in multiple states. For more information follow @Shiekh on Instagram and visit Shiekh.com Media Contact: Pia Malihi | Full Scope PR pia@fullscopepr.com # # # Contact Details Pia Malihi pia@fullscopepr.com Company Website https://takenolsstore.com/

September 26, 2024 01:12 AM Eastern Daylight Time

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Little Spoon Becomes The First and Only Baby Food Maker In the U.S. To Publicly Set EU-Aligned Safety Standards and Share Test Results for Heavy Metals, Pesticides + Plasticizers

Little Spoon

In a groundbreaking move for the baby food industry, Little Spoon, the largest online baby and kids food company in the United States, today becomes the first and only brand in the country to unveil its testing standards and results for heavy metals, pesticides and plasticizers, making a commitment to never sell any product that falls short of its strict limits. The launch of this significant transparency initiative comes in response to the ongoing national discussion about baby food safety, the urgent need for stricter industry standards, and staggering statistics from a recently commissioned study of 2,000 American parents with children under 2 years old. As national conversations on baby food safety rapidly gain steam, it has become impossible to ignore the concerning headlines on toxic levels of heavy metals, grocery store brand misinformation and deteriorating consumer trust. Little Spoon partnered with Talker Research to conduct a survey of 2,000 American Parents to pulse check the needs and standards of American parents, and the results uncovered astonishing levels of mistrust and concern around industry safety, federal regulations, and overarching brand commitment. In fact, 95% of parents agree that baby food brands should be doing more to address baby food safety concerns— and only 9% report a ‘high degree’ of trust in baby food companies. “Quality nutrition and confidence in the products that fuel your family are rights, not privileges.” said co-founder and CEO, Ben Lewis. “We view this as a fundamental responsibility for our industry and a key reason why Little Spoon exists in the first place. The standards for children’s food in the U.S. are maddeningly low. Parents deserve better, and we are doing our part to finally deliver what they deserve.” Established to bring change to a century old industry, Little Spoon is once again raising the bar in the category by testing and sharing results for every batch of baby food for 500+ contaminants including heavy metals, pesticides, glyphosate and plasticizers. With no current federal regulations set for limiting the levels of chemical contaminants in baby food in the U.S., Little Spoon has aligned its testing standards for heavy metals with the European Union (EU), a long-standing, trusted standard for safety and excellence in the baby space. Consumers can see exact testing limits for each contaminant through a dashboard viewable for every Babyblend product on the brand’s website and can confidently purchase products knowing Little Spoon will not sell any products that do not meet these standards. “This generation is plagued by concern regarding baby food safety — and for good reason.” said co-founder and Chief Product Officer of Little Spoon, Angela Vranich. “We have always crafted our products with the utmost care, using certified organic ingredients and differentiated processing. We knew we could meet the rigorous EU testing limits for heavy metals in our baby food, and it quickly became our obsession to provide the level of transparency parents truly deserve.” To draw further attention to this crucial issue for Little Spoon consumers and parents nationwide, the ‘Little Spoon, Big Change’ initiative will be driven by a comprehensive 360-degree marketing campaign launching today. Designed to meet parents’ growing demands for transparency and baby food safety, the campaign will feature media partners, celebrities, tastemakers, and experts including an expanded advisory panel which now features world-class experts in public policy and academics specializing in heavy metals. As a topic often fraught with fear mongering tactics, Little Spoon is leveraging experts, educators and a new AI-powered chatbot on their site to provide education for parents and support the wide-ranging questions that come with baby food safety. "We won't see large-scale changes until companies like Little Spoon take action," said Dr. Bruce Lanphear, an advisor to Little Spoon who studies childhood exposure to toxic chemicals. "Companies don't need to wait for regulations—they can lead the charge.” Test results for every Little Spoon Babyblend, alongside detailed ingredient sourcing information are now available on LittleSpoon.com, with plans to roll out additional transparency measures for their robust portfolio of products in the coming months. For complete details on the ‘Little Spoon, Big Change’ initiative including Little Spoon’s testing process, regulation limits, test results, and overall commitment to baby food safety, please visit LittleSpoon.com and follow @littlespoon on Instagram. Little Spoon is the leading direct-to-consumer kid’s food brand on a mission to make parents' lives easier, and kids healthier through high-quality, accessible feeding solutions from baby’s first bites through the big kid years. Little Spoon is conveniently delivering the future of kid’s food right to parent’s doorsteps with integrated products that age with your child through a portfolio of freshly-made baby food, early finger foods, toddler + big kid meals, and snacks that meet the modern standard on quality, nutrition and value. Since launch, the company has delivered more than 50 million meals, helping to simplify the lives of hundreds of thousands of parents across the U.S.. With more than 90% of new parents identifying as millennials, Little Spoon is here to disrupt the +$100B children's health and wellness market, offering modern solutions, trusted resources, and new ways to connect with a network of advisors and parents just like you. Learn more at LittleSpoon.com, or find Little Spoon on Instagram at @LittleSpoon. Contact Details Powers PR Alex Turk +1 516-306-2373 alext@powers-pr.com

September 25, 2024 09:03 AM Eastern Daylight Time

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drive21, Van Wagner Collaborate to Elevate In-Venue Branding and Fan Engagement Across College Athletics

drive21

drive21, a leader in experiential design and marketing solutions, today announced a strategic relationship with leading collegiate athletics marketing agency, Van Wagner to become a preferred experiential graphic design and implementation provider for Van Wagner. Van Wagner is recognized for its expertise in collegiate sponsorship sales and multi-media rights and will collaborate with drive21 to redefine branding strategies, drive revenue growth, and create Name, Image and Likeness (NIL) execution opportunities in the collegiate sports industry. Through this relationship, Van Wagner’s collegiate clients will be afforded advantageous pricing and access to drive21’s suite of services to provide innovative branding and design solutions across their venues; driving innovative solutions that bridge the gap between brand aspirations and reality, creating immersive environments that resonate with audiences and drive tangible business results. "This relationship represents a significant step forward in our mission to transform sports and entertainment venues into impactful environments that are also powerful marketing tools," said Warren Godridge, drive21 Founder and President. "By collaborating with Van Wagner, we can leverage our creativity and expertise to deliver a consistent brand experience across all venues, enhancing the value for brands, universities, and fans alike." “Traditional approaches often focus solely on aesthetics and overlook the potential to maximize partnership, sponsorship and NIL opportunities, leaving untapped value on the table” said John Libro, Head of Sports and Entertainment at drive21. “Working with Van Wagner College will allow us to push the boundaries of experiential design and transform collegiate athletic facilities into dynamic revenue-generating tools that engage fans and drive real business growth.” This relationship may also offer an even more comprehensive solution to collegiate clients by providing new NIL revenue streams. Through this collaboration with drive21, a portion of the facility’s expenditure can be reallocated to the universities’ NIL efforts. This allows universities to offer a more engaging experience for athletes and fans while creating dynamic environments supporting athletic performance, fan engagement and brand partnerships. "drive21’s ability to seamlessly integrate brand experiences into our facilities is a game-changer for our clients,” said Mark Donley, Chief Revenue Officer at Van Wagner College. “Through our arrangement with drive21, our university clients have an opportunity to access the expertise of drive21 to not only enhance their facilities but also ensure a consistent and high-quality experience for a variety of initiatives at an advantageous rate. It's truly a win-win-win scenario." The first major joint effort was a collaboration at Florida International University for the brand implementation of the newly named Pitbull Stadium. drive21 and Van Wagner played a key role in creating cohesive branding for the first college athletic venue named after a musician, exampling the transformative potential of experiential design and strategic branding. To learn more about the partnership, or drive21’s sports, entertainment and hospitality solutions, please visit www.drive21.com. About drive21 drive21 elevates the sports, entertainment, and hospitality industries by delivering one-of-a-kind branded venue experiences. A leader in experiential design and marketing solutions, drive21 bridges the gap between imagination and reality to deliver functional and impactful environments through design, fabrication, implementation, and holistic project management. Servicing organizations including MLB, MLS and NCAA institutions, drive21 helps its clients maximize partnership and sponsorship revenue and turns ordinary environments into extraordinary works of art. For more information, visit www.drive21.com. About Van Wagner Van Wagner is a leading sports advertising and entertainment agency with global expertise in filmed and live entertainment, sponsorship sales, multi-media rights, and aerial advertising. Van Wagner creates, advises, and sells for world-class teams, leagues, brands, and properties. An innovator in the sports and media business, Van Wagner is a global leader in high-impact broadcast visible signage throughout the MLB, NBA, NCAA, and international soccer, sponsorships sales, college multi-media rights, and in-venue content production at the world’s biggest sporting events. For more information, visit www.vanwagner.com. Contact Details Hot Paper Lantern Jackson Gaskins jgaskins@hotpaperlantern.com Company Website https://drive21.com

September 25, 2024 08:00 AM Eastern Daylight Time

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AI Unpacks Generational Stereotypes, Highlighting Key Differences, but Beer Bridges the Gap

AIport

What happens when you ask generative AI models to depict Baby Boomers, Gen X, Millennials, and Gen Z? You might expect tech-challenged Boomers and avocado-loving Millennials. But what you get is far more interesting and in some cases, unexpected. A joint research project conducted by AIport and Turing Post last month analyzed over 1200 AI-generated images across four different models—Stable Diffusion, Midjourney, YandexART, and ERNIE-ViLG. The findings have revealed both familiar stereotypes and surprising quirks about how AI perceives these generations. Sad Boomers, Happy Zoomers? Contrary to the carefree Boomer stereotype, AI models like Midjourney depict Baby Boomers as introspective, or even somber, often bundled up and gazing wistfully into the distance—a reflection, perhaps, of their disillusionment with the unfulfilled ideals of the 1960s cultural revolution. However, the ERNIE-ViLG model, likely trained on datasets with a more collectivist cultural slant, shows 93% of Boomers smiling. This fascinating contrast underscores the cultural differences embedded in different AI models. Meanwhile, Gen Z’s images are vibrant and diverse, reflecting their reputation as a generation that embraces individuality, inclusivity, and self-expression. The AI-generated images depict Zoomers in colorful, highly detailed scenarios, making them the most visually distinct generation in the study. Generations Through the AI Lens The research explored how generations are portrayed in five key aspects of life: identity, relationships, work, lifestyle, and consumer habits. The AI models revealed consistent patterns and stereotypes; for example, males predominated in the depictions of Boomers and Gen Xers across all four models, while many images of Millennials and Zoomers showed greater diversity and more female representation. Surprisingly, Gen X appears to be the least well-understood generation by AI, characterized by fewer defining features compared to all other generations, likely due to the limited amount of training data available. The one stereotypical Gen X leitmotif that AI consistently identifies is their fondness for flannel shirts—an unmistakable symbol of the 1990s grunge scene worn by Gen Xers who were rebellious teenagers and young adults during that era. As for one (un)expected commonality… It’s beer. Whether they’re Millennials job-hopping or Boomers reminiscing about the good old days, AI consistently showed beer in 34% of the produced images across all generations. Prompt Engineering and AI Insights The prompts for this research were carefully crafted to avoid bias, using neutral phrases like "A Millennial at work" or "A Boomer relaxing." The results offer a telling look at how generative AI models mirror societal stereotypes, often shaped by the data they're trained on. These findings open the door to deeper discussions on how AI reflects, and sometimes distorts, cultural narratives. "Whether we think we can learn about generations from these images depends upon how confident we feel that the training data that went in is an accurate image of the self identity of a group,” explains Senior Engineer and Sociologist Stephanie Kirmer, who analyzed the findings. “For the younger sets, I don’t think we can know how much of it is media representation created by people outside the group versus how much is selfie-style personal expression. Some of what we’re getting, especially for the older groups who don’t contribute as much self-generated visual media online, is perceptions of that group from advertising and media, which we know has inherent flaws." About the Study The study examined the outputs of four globally recognized generative AI models, each with distinct aesthetic and cultural nuances, providing a comprehensive look at how each generation is portrayed visually. The selected models included Stable Diffusion, Midjourney, YandexART, and ERNIE-ViLG, offering diverse perspectives from different regions across the globe. Conclusion Whether confirming or contradicting societal stereotypes, AI-generated images provide a fascinating snapshot of how technology interprets generational differences. The fact that beer remains a unifying theme across all four models shows that, no matter our age, some things—like enjoying a cold one—transcend generational divides. To learn more about the project, visit https://www.aigenerations.tech/. Hero images for the media: Google Drive Link About AIport AIport is an emerging community of AI/ML enthusiasts and practitioners with a goal of providing a truly global view of the AI/ML/DS landscape. https://www.blog.aiport.tech/ About Turing Post Turing Post is everything you need to make smarter decisions about AI. https://www.turingpost.com/ Contact Details Nick Leighton nick.leighton@nettresultsllc.com Company Website https://www.aigenerations.tech/

September 23, 2024 10:00 AM Eastern Daylight Time

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Largest Immersive Gaming Facility in the World Is Now Open at Toronto’s Stockyards

Activate

Activate, the world’s first active gaming facility and viral sensation on TikTok, is thrilled to announce the opening of its largest location in the world, situated in Toronto's vibrant Stockyards district. The new facility, located at 30 Weston Rd, Unit C209, promises an unparalleled entertainment experience that blends cutting-edge technology with physical activity. Activate Stockyards boasts an impressive facility spanning 19,218 square feet, making it the largest of its kind in the region. This expansive venue houses 19 unique game rooms, including the TikTok famous Mega Grid, adrenaline-fueled Lasers, Push with 452 light-up buttons and the precision-driven Strike, all designed to deliver a distinct and thrilling experience. The sheer size and vast selection of game rooms offer visitors plenty of space to engage in a wide range of interactive and immersive adventures. ”We are thrilled to be bringing Activate's largest location in history to Canada’s largest city, Toronto,” proclaimed Adam Schmidt, Founder & CEO of Activate. “This exciting new location is a fantastic addition to the vibrant Stockyards neighborhood. We can't wait for Toronto’s bustling community to experience the largest entertainment concept in the world.” Activate is taking over the immersive gaming world, now dominating 40 locations across the United States and Canada, and it shows no signs of slowing down. As the first active gaming facility to become a TikTok sensation, Activate has built a social media empire, captivating millions with its innovative, interactive experiences. Their unique approach to active gaming has set them apart, cementing their position as a leader in the entertainment world. Internationally, Activate is expanding with a new Dubai location and a UK debut in December 2024. For a sneak peek into Activate’s dynamic gaming experience, click here. Join the Inner Circle to be the first to hear about new locations, behind-the-scenes information, deals, and more. Please find imagery assets here. Activate is the world’s first active gaming experience where players #EnterTheGame. Activate offers a unique blend of physical activity and gaming that promotes a healthy lifestyle. Each Activate location provides fun and interactive rooms for players to compete, earn stars and track achievements. With the global headquarters located in Winnipeg, Canada, Activate has grown to 30 locations across Canada, the U.S. and now the world! To join the active gaming movement, visit playactivate.com. Follow Activate on social media: Facebook: Activate Instagram: @activategames TikTok: @activategames Contact Details Jive PR + Digital Jalila Singerff +1 613-614-6777 jalila@jiveprdigital.com Company Website https://playactivate.com

September 23, 2024 08:00 AM Eastern Daylight Time

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Siti Non AAMS - Migliori Siti Casino & Scommesse 2024

AM Europe

Sono sempre di più gli utenti italiani che scelgono di scommettere sui cosiddetti siti non AAMS. Questi concessionari operano con licenze internazionali e garanwtiscono l’accesso a generosi bonus senza deposito, a più metodi di pagamento, e a dei giochi che sui siti AAMS solitamente non si trovano. Chiunque sia alla ricerca di siti di scommesse legali in Italia seppur al di fuori della normativa AAMS, in questa guida andremo proprio a fornire una panoramica sui migliori operatori di questo genere. Tabe di Siti Non AAMS & Casino non AAMS Perché gli Italiani Scelgono i Bookmaker Non AAMS Gli italiani scelgono i siti non AAMS per tante motivazioni differenti, che si rifanno principalmente a ciò che riguarda le promozioni, alla selezione di giochi e prodotti disponibili e alla struttura di diverse funzionalità delle piattaforme stesse. Bonus più generosi Meno restrizioni Ampia varietà giochi Programmi VIP esclusivi Tornei giornalieri Lista dei Migliori Siti non AAMS Panoramica Di seguito, proponiamo una lista di quelli che a nostro parere sono i migliori siti non AAMS, con tanto di descrizione dei punti di forza di ciascuno: HappySlots: Questo casinò rappresenta il paradiso per gli amanti delle slot machine, in quanto propone una selezione capace di abbracciare migliaia di titoli differenti. I giocatori possono quindi esplorare una miriade di temi e funzionalità all’interno di HappySlots, portale capace di far provare sempre qualcosa di nuovo ai propri utenti, soprattutto grazie alle frequenti aggiunte di titoli originali. WildTokyo: Perfetto per chi cerca dell’adrenalina su base quotidiana, questo casinò online si ditingue per offrire promozioni e gare con premi che vengono assegnati ogni giorno; infatti, all’interno di questo portale vengono proposte giornalmente nuove sfide e bonus che rendono l’esperienza di gioco sempre dinamica e ricca di opportunità da cogliere per usufruire di ricompense extra. ProntoBet: Con un palinsesto sportivo che non ha nulla da invidiare ai principali bookies mondiali, ProntoBet è sicuramente il sito ideale per gli appassionati di scommesse sportive. L’offerta di ProntoBet copre tutti gli eventi sportivi globali e consente agli utenti di scommettere su una vasta gamma di discipline con quote molto competitive. Winsane: Questo portale è rinomato per il suo eccellente e ben strutturato programma fedeltà; grazie a quest’ultimo, i giocatori più assidui possono beneficiare di bonus esclusivi e trattamenti VIP personalizzati che vanno a premiare la loro fedeltà con vantaggi unici e premi assegnati su misura. Cashwin: Con un’offerta che prevede la fruizione costante di nuove promozioni per nuovi iscritti e utenti già registrati, Cashwin è senza dubbio l’ideale per chi ama passare il proprio tempo nel tentativo di sfruttare al meglio dei bonus vantaggiosi. Le promozioni disponibili sono generose e spesso sono pensate per incrementare percentualmente i fondi di gioco che vengono depositati in maniera davvero significativa. Quickwin: La punta di diamante di Quickwin è costituita dalla lounge dedicata al casinò live, in cui è possibile trovare tutti i giochi con croupier dal vivo. Gli amanti dell’interattività e della dinamicità del casinò potranno trovare un’ampia selezione di titoli in grado di ricreare fedelmente l’ambiente di un casinò reale, soprattutto grazie alla qualità dei giochi offerti. Perchè gli Italiani scelgono i Siti non AAMS Come detto in precedenza, i siti non AAMS stanno rapidamente guadagnando popolarità tra gli scommettitori italiani, poiché offrono una serie di vantaggi che superano quelli dei bookmaker regolamentati dall’AAMS. Grazie a bonus mediamente più generosi, metodi di pagamento che includono anche le criptovalute e selezioni di giochi più estese, questi siti stanno diventando sempre più gettonati. Qui sotto abbiamo preparato un elenco di motivi, dettagliati uno per uno, per i quali gli utenti si stanno spostando sempre più verso queste alternative ai casinò online tradizionali. Bonus e promozioni: I siti non AAMS propongono bonus più generosi rispetto alle controparti regolate dall’AAMS e spesso assicurano anche giri gratuiti e bonus senza deposito che sono sempre molto graditi a tutti gli utenti; Metodi di pagamento: I siti non AAMS supportano molti altri metodi di pagamento come le criptovalute oltre alle opzioni più classiche come possono essere le carte di credito e i portafogli elettronici; Selezione di giochi: Offrendo una gamma di giochi da casinò tendenzialmente più ampia rispetto ai casinò normali, i siti non AAMS si fanno preferire per la maggiore varietà a cui gli utenti possono avere accesso; Licenze e sicurezza: Pur non regolamentati dall'AAMS, i siti non AAMS possiedono licenze internazionali, assicurando elevati standard di sicurezza e protezione per dati personali e transazioni finanziarie. Supporto clienti: Il supporto multilingue dei siti non AAMS, solitamente disponibile tramite chat live, email e telefono, garantisce assistenza immediata che permette di risolvere ogni tipologia di problema efficientemente. Pro e Contro dei Siti Non AAMS Pro: Ampia gamma di bonus, varietà di giochi, flessibilità nei pagamenti e meno restrizioni. Contro: Il servizio clienti di queste piattaforme a volte potrebbe tardare più del dovuto nelle risposte. Cos'è un sito di scommesse sportive non AAMS? Un sito di scommesse sportive non AAMS è una piattaforma che opera senza la licenza italiana rilasciata dall’Agenzia delle Dogane e dei Monopoli, ma che possiede comunque una attestazione internazionale. Questi siti consentono agli utenti di piazzare scommesse sempre sulla maggioranza degli eventi sportivi internazionali, ma offrendo un numero di mercati che generalmente va oltre a quello proposto dai siti AAMS; infatti, come abbiamo già sottolineato, le piattaforme non AAMS sono note per avere regole meno rigide sotto tutti i punti di vista, il che significa spesso limiti di scommessa più alti, bonus più generosi e metodi di pagamento più variegati. Come registrarsi nei Siti non AAMS Registrarsi su un sito di scommesse non AAMS spesso passa da un processo più rapido rispetto a quello che si deve affrontare all’interno dei casinò tradizionali, grazie a procedure meno rigide in termini di raccolta dati. In molti casi, i siti non AAMS consentono di registrarsi con metodi alternativi come Google o Apple ID, in modo da abbattere le tempistiche necessarie per creare un nuovo conto di gioco. Inoltre, al posto della classica procedura di convalida obbligatoria dei documenti entro 30 giorni, come richiesto dai casinò AAMS per evitare la sospensione del conto, i siti non AAMS adottano procedure di Know Your Customer (KYC) meno invasive; questo significa che, anche se il processo di KYC non viene portato a termine correttamente, l'utente può comunque accedere liberamente a tutte le funzionalità del casinò ad eccezione dei prelievi, che vengono resi disponibili solo dopo aver completato questa procedura. Visitare il sito scelto: La prima cosa da fare è recarsi nella homepage del sito di scommesse non AAMS; Cliccare su "Registrati": Successivamente, bisogna cliccare sul pulsante di registrazione che è solitamente piazzato in alto a destra nella pagina principale del sito; Compilare il modulo: Arrivati qui, toccherà all’inserimento dei propri dati personali, come nome, cognome, indirizzo email e numero di telefono; alcuni siti potrebbero richiedere anche la creazione di un nome utente; Verificare l'account: Infine, bisognerà inviare una copia dei documenti richiesti per la verifica dell'identità, passaggio fondamentale per sbloccare la possibilità di effettuare dei prelievi. Giochi da casinò disponibili I siti non AAMS sono particolarmente indicati per gli amanti dei giochi del casinò, in quanto spesso e volentieri sono presenti decine di alternative per ciascuna delle categorie di giochi principali. Giochi da tavolo I giochi da tavolo includono grandi classici come blackjack e baccarat, con molte varianti alternative utili per adattarsi a diversi stili di gioco. Slot Dalle slot tradizionali alle video slot con grafiche particolareggiate, queste piattaforme offrono anche titoli con jackpot progressivi capaci di portare a vincite significative. Casinò live Il casinò live offre un'esperienza estremamente realistica con un croupier reale e include tsvoli di giochi come roulette, blackjack e poker dal vivo. Blackjack Il blackjack è disponibile sia offline live, permettendo ai giocatori di scegliere se giocare a delle partite automatizzate o in diretta con dei croupier. Roulette Le varie versioni di roulette includono quella europea, quella americana e quella francese, con sempre diverse opzioni di scommessa disponibili sia virtualmente che live. I casinò non AAMS sono legali in Italia? Sì, i siti non AAMS sono legali anche in Italia nonostante operino tramite delle licenze internazionali, come possono essere quelle rilasciate da Malta o Curaçao, piuttosto che con licenze AAMS. Questo significa che, pur non essendo regolamentati direttamente dal governo italiano, questi portali possono comunque offrire servizi di scommessa e gioco d'azzardo ai residenti in Italia senza alcuna implicazione a livello legale. Per chiudere, pensiamo sia importante ricordare che, nonostante sia sempre garantito che questi casinò operano legalmente, i giocatori dovrebbero sempre verificare la licenza sotto cui il sito opera per assicurarsi che siano protetti e che i loro fondi siano al sicuro. Metodi di deposito e prelievo Spesso, i siti di scommesse non AAMS danno la possibilità agli utenti di prelevare e versare denaro tramite decine di metodi di pagamenti differenti da quelli solitamente messi a disposizione dai concessionari. Queste piattaforme sono ben consapevoli dell'importanza di effettuare transazioni rapide e sicure, e per questo motivo mettono a disposizione diverse opzioni per soddisfare le esigenze di un pubblico internazionale; che si tratti di carte di credito, portafogli elettronici o bonifici bancari, ogni giocatore può trovare il metodo di pagamento che meglio si adatta alle proprie preferenze e necessità. L'inclusione delle criptovalute in alcuni di questi siti rappresenta un ulteriore passo avanti verso la modernizzazione delle operazioni finanziarie, in modo da garantire non solo velocità, ma anche un alto livello di anonimato e sicurezza. Vediamo ora nel dettaglio quali sono le opzioni di pagamento più comuni disponibili sui siti di scommesse non AAMS. Visa: La carte di credito Visa costituiscono uno dei metodi di pagamento più popolari e diffusi nei siti di scommesse AAMS e non. Visa garantisce che le transazioni siano sempre protette da tecnologie avanzate di crittografia, in modo da ridurre al minimo il rischio di frodi. Inoltre, la velocità delle operazioni consente ai giocatori di avere i fondi disponibili immediatamente per scommettere; tuttavia, è bene ricordare che per alcuni siti potrebbero essere applicate commissioni e che i tempi di prelievo potrebbero variare sulla base delle condizioni imposte dal concessionario. Mastercard: Mastercard è un'altra carta di credito largamente accettata all’interno dei siti non AAMS. Anche questa opzione prevede la stessa rapidità nelle transazioni e la protezione dalle frodi grazie all’utilizzo di sistemi di sicurezza piuttosto avanzati; come per Visa, anche con Mastercard si possono incontrare tempi di attesa per i prelievi che variano a seconda del sito, ma la trasparenza delle commissioni e la velocità nelle operazioni hanno reso questo metodo una scelta molto popolare; Paypal: Paypal è uno dei portafogli elettronici più utilizzati nei siti non AAMS e non. La sua popolarità deriva dalla facilità d'uso della sua interfaccia e dalla velocità di evasione delle transazioni, i cui processi permettono ai giocatori di effettuare depositi e prelievi in pochi click e secondi. Inoltre, ricordiamo che Paypal è sinonimo di un ulteriore livello di sicurezza, in quanto funge da intermediario tra il conto bancario del giocatore e il sito senza che le informazioni sensibili vengano mai condivise direttamente con il casinò. Neteller: Neteller è uno dei portafogli elettronici preferiti dai giocatori che utilizzano i siti non AAMS per via della sua alta velocità e semplicità. Le transazioni con Neteller sono quasi istantanee e permettono di trasferire fondi rapidamente, sia per i depositi che per i prelievi. Inoltre, questo portafoglio elettronico assicura un elevato livello di sicurezza, grazie a sistemi di crittografia avanzati. Bonifico bancario: Operare tramite il bonifico bancario rimane un metodo tradizionale, utilizzato soprattutto da chi preferisce trasferire fondi direttamente dal proprio conto corrente senza l'intermediazione di carte o portafogli elettronici. Anche se questo metodo offre un’elevata sicurezza, grazie al sistema bancario regolamentato, i tempi di elaborazione possono essere più lunghi rispetto ad altre opzioni, richiedendo fino a 5 giorni lavorativi per il completamento di qualsiasi tipo di giocata. Bonus e Promozioni sui Siti non AAMS Uno dei motivi principali per cui molti giocatori scelgono i siti non AAMS sta nella generosità e varietà dei bonus e delle promozioni disponibili. Questi casinò offrono promozioni molto più competitive rispetto ai siti regolamentati dall’AAMS, con cifre spesso superiori, bonus senza deposito, e programmi fedeltà più vantaggiosi. Molti siti non AAMS propongono anche promo come i cashback settimanali o mensili, che permettono di vedersi restituita una percentuale delle perdite subite per via delle giocate non vincenti. Infine, i tornei giornalieri e le race con premi extra sono una caratteristica comune, capace di attirare i giocatori con promozioni dinamiche e costanti. Ecco alcune delle offerte più comuni: Free Spins: Si tratta di gratuiti offerti su slot selezionate, ideali per provare nuovi giochi senza rischiare il proprio denaro. Bonus senza deposito: Uno dei preferiti dai nuovi iscritti, permette di iniziare a giocare senza dover effettuare un deposito con i propri soldi. Wagering: Condizioni di giocata che talvolta sono più favorevoli rispetto ai siti AAMS, consentendo di soddisfare i requisiti di scommessa in modo più semplice. Cashback: Alcuni casinò non AAMS offrono un ritorno percentuale sulle perdite nette, in modo da garantire ai giocatori un piccolo rimborso. Software disponibile sui bookmaker non AAMS I siti non AAMS collaborano con alcuni dei migliori provider di software nel settore del gioco d’azzardo allo scopo di garantire un’esperienza fluida in ogni momento. Questi provider sono responsabili dello sviluppo di giochi equi, con funzionalità innovative e grafiche di alta qualità. Curacao I siti di scommesse con licenza rilasciata dalla giurisdizione di Curacao collaborano con alcuni dei più celebri provider di software della scena, tutto per offrire giochi godibili ed equi. NetEnt Betsoft Evolution Gaming Pragmatic Play Yggdrasil MGA Anche i siti regolati dalla Malta Gaming Authority (MGA) collaborano con fornitori di software leader del settore per assicurare che l’esperienza di gioco sia la migliore possibile. Microgaming Play’n GO Quickspin Thunderkick Evolution Gaming Le Nostre Conclusioni In conclusione, ci siamo convinti del fatto che i siti non AAMS rappresentano senza dubbio un’alternativa valida per chi cerca maggiore libertà, promozioni più generose e un elenco di giochi più fornito rispetto alle disponibilità dei casinò tradizionali. Anche se non regolamentati direttamente dall’AAMS, molti di questi siti operano con licenze riconosciute a livello internazionale che garantiscono inconfutabilmente un livello di sicurezza molto elevato. Tuttavia, ricordiamo che è fondamentale che i giocatori siano consapevoli dei possibili rischi che possono correre e che scelgano piattaforme con una buona reputazione e licenze affidabili come quelle di cui abbiamo parlato all’interno di questa stessa panoramica. Domande Frequenti (FAQ) È sicuro giocare all’interno di un sito non AAMS? Sì, i siti non AAMS che possiedono licenze internazionali come quelle di Curaçao o Malta offrono livelli di sicurezza paragonabili a quelli AAMS. Quali bonus posso ottenere sui siti non AAMS? I siti non AAMS offrono bonus senza deposito, giri gratuiti, cashback e promozioni personalizzate, solitamente in misura maggiore rispetto ai bookmaker AAMS. Posso prelevare le vincite dai siti non AAMS? Sì, i siti non AAMS permettono prelievi tramite carte di credito, portafogli elettronici come Neteller e PayPal, bonifici bancari, criptovalute e non solo. I siti non AAMS sono legali in Italia? Sì, i siti non AAMS sono legali per i giocatori italiani; tuttavia, essendo regolamentati da autorità internazionali, operano al di fuori del sistema di licenze italiano. Contact Details Berardo Bianchi +39 035 0445 9954 Berardo@itsitinonaams.com Company Website https://www.casinolistingonline.com/

September 20, 2024 04:09 AM Eastern Daylight Time

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Industry Update: 3 Exciting Precision Oncology Players to Watch Following Summit’s Meteoric Rise: Silexion, Nuvectis, Scorpian

Global Markets News

Summit Therapeutics (NASDAQ: SMMT) recently captured headlines with the release of its Phase 3 data for ivonescimab, a targeted NSCLC therapy that has generated substantial buzz. The results from its trial conducted in China showed a dramatic 49% reduction in the risk of disease progression or death compared to Merck’s Keytruda, signaling a potentially disruptive force in NSCLC treatment. However, the news wasn’t without its concerns—since the trial data originates from China, there are questions about its applicability to broader, global populations. As noted by BMO Capital Markets’ Evan Seigerman: “Results may or may not be generalizable beyond the China-focused patient population initially assessed.” Despite this, Summit’s valuation has risen by over 100%, now approximating $19 billion. With such a high valuation, the company could see limited room for further significant gains, leading many in the industry to explore other emerging opportunities in precision oncology. Alongside Summit, there are quite a few other players in the field. Some if these companies have even already shown promising initial results and could see similar success in the future if they were to report positive results. These emerging players are worth watching for those interested in following precision oncology drug candidates and pipelines. Among them are precision oncology innovators such as Silexion Therapeutics, Nuvectis Pharma, and Scorpion Therapeutics, which we discuss below. Silexion Therapeutics: Disrupting the KRAS-Driven Cancer Space Silexion Therapeutics (NASDAQ: SLXN) is another under-the-radar player in the precision oncology space, with a focus on KRAS-driven cancers—a notoriously difficult target in oncology. While current small-molecule KRAS inhibitors are making progress, they are often limited to specific mutations, such as KRAS G12C, which accounts for a small percentage of cancers. Silexion’s RNA interference (RNAi) approach offers a broader solution, targeting a wider spectrum of KRAS mutations, particularly in pancreatic cancer, one of the deadliest and most treatment-resistant cancers. At the heart of Silexion’s approach is its LODER™ platform, which delivers siRNA directly to the tumor site, silencing KRAS mutations at the genetic level. This localized delivery not only increases efficacy by concentrating the treatment in the tumor, but it also reduces systemic side effects. Silexion’s next-generation candidate, SIL-204, is an optimized siRNA formulation designed to target pan-KRAS G12x mutations, positioning it to treat a broader range of KRAS-driven cancers beyond pancreatic cancer, such as lung and colorectal cancers. In Phase 2 trials for locally advanced pancreatic cancer, Silexion's LODER™ platform showed a 9.3-month improvement in overall survival when combined with standard chemotherapy. Additionally, the objective response rate (ORR) increased from 20% with chemotherapy alone to 55% with the combination, and in some cases, tumors that were initially non-resectable became operable after treatment with LODER™. These results are especially encouraging given the limited options available for pancreatic cancer patients. SIL-204, is expected to enter Phase 2/3 clinical trials in 2025-2026. What makes Silexion particularly intriguing is its current market valuation. Valued at aproximatly just ~$9 million following its SPAC merger, the company’s valuation could be perceived as low when compared to some of its peers, especially given its innovative technology and promising clinical achievements. Some have wondered whether this low valuation has more to do with dynamics post-SPAC companies. If Silexion can report positive results in its later-stage trials, the company’s outlook could dramatically improve, reflecting the potential of its RNAi-based platform. Like NXP900, SIL-204 could potentially have vast applications across multiple KRAS-driven cancer types, making Silexion a company to watch closely as it advances through clinical development. Nuvectis Pharma: Targeting NSCLC and Beyond by Inhibiting SRC/YES1 Kinases Nuvectis Pharma (NASDAQ: NVCT) has been quietly making strides in the precision oncology sector, developing innovative therapies aimed at overcoming treatment resistance in hard-to-treat cancers. Its lead candidate, NXP900, targets NSCLC by inhibiting the SRC/YES1 kinases, which play critical roles in cancer cell survival and resistance to current therapies. This approach positions NXP900 as a potential game-changer in the treatment of NSCLC, particularly in patients who have developed resistance to EGFR and ALK inhibitors, such as AstraZeneca’s Tagrisso and Novartis’ Alecensa. NXP900 is still in the early stages of clinical development, currently undergoing Phase 1 trials. However, preclinical studies have already shown that it has strong anti-tumor activity in resistant NSCLC models. Even more promising is its potential application beyond NSCLC. Like Summit's ivonescimab, NXP900 focuses on resistance, but it also has broader applications due to its ability to target multiple cancer types driven by SRC/YES1 pathways. This versatility makes it a promising asset not just for NSCLC but also for other difficult-to-treat cancers like squamous cell carcinomas. In addition to NXP900, Nuvectis is advancing NXP800, another precision oncology candidate that is further along in the clinical development process. NXP800 is currently in Phase 1b trials, targeting ARID1a-mutated cancers such as ovarian and endometrial cancers. The early clinical data for NXP800 is promising, showing positive responses in patients with platinum-resistant ovarian cancer. With two strong candidates in the pipeline, Nuvectis is positioning itself as a formidable player in the precision oncology landscape. As Summit’s ivonescimab continues to gain attention, Nuvectis’ earlier-stage NXP900, with its NSCLC focus and beyond, could see similar success in the future if clinical results continue to trend positively. Scorpion Therapeutics: Pioneering Mutant-Selective Therapies Scorpion Therapeutics is redefining the frontier of precision oncology with its focus on delivering highly selective small molecules targeting validated and previously undruggable cancer mutations. Its lead candidate, STX-478, is a mutant-selective, allosteric PI3Kα inhibitor currently in Phase 1/2 trials for advanced solid tumors. Early data presented at the ESMO Congress 2024 highlighted its potential, with STX-478 demonstrating a 23% overall response rate in breast cancer and a 21% response rate across all tumor types, positioning it as a potentially best-in-class PI3Kα inhibitor. STX-478 is notable for its ability to spare wild-type PI3Kα activity in normal tissues, avoiding the toxicities seen with previous PI3Kα inhibitors, such as hyperglycemia and rash. Tumor reductions were seen in 72% of patients treated with STX-478 as a monotherapy, with circulating tumor DNA levels dropping in 86% of patients. This mutant-selective precision could help overcome the limitations of existing PI3Kα inhibitors, which have struggled with dose-limiting toxicities. In July 2024, Scorpion raised $150 million in a Series C financing round, co-led by Frazier Life Sciences and Lightspeed Venture Partners. The additional funding will support the advancement of STX-478 and other pipeline assets, positioning Scorpion for further clinical success. Scorpion’s pipeline includes a broad range of wholly-owned compounds that target both validated and novel cancer targets, positioning the company for future expansion into larger patient populations. As STX-478 progresses through clinical development, Scorpion is poised to become a significant player in the precision oncology space, making it another company worth watching closely. Optimistic Outlook for Precision Oncology The precision oncology space is experiencing a golden era of innovation, with companies like Summit Therapeutics, Nuvectis Pharma, Silexion Therapeutics, and Scorpion Therapeutics leading the charge. As the focus shifts towards targeted therapies that address resistance mechanisms, the market is increasingly favoring companies with novel approaches and broad applications. Summit’s meteoric rise has shown that there is tremendous potential for companies that can demonstrate efficacy in overcoming cancer resistance. While Summit has already captured much of the current attention, companies like Nuvectis, Silexion, and Scorpion, with their earlier-stage pipelines, offer exciting opportunities for the industry to keep a close eye on. As these companies continue to report clinical data and advance through trials, the potential for breakthroughs in treating some of the most difficult cancers grows stronger. With targeted therapies offering the possibility of overcoming resistance without the need for chemotherapy, the future of cancer treatment looks brighter than ever. For those in the oncology space, keeping a close eye on emerging players like Nuvectis, Silexion, and Scorpion could lead to transformative developments as the field of precision oncology continues to evolve. * * * This update may include speculative forward looking statements. Readers are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and that actual results may differ materially from those in the forward-looking statements as a result of various factors. the BioTech and Pharma industries are volatile and risky and readers are advised to seek out preffesional advice in the relevent feilds from licensed profesionals. This update is for informational purposes only and is not intended to serve as financial, investment or any form of professional advice, recommendation or endorsement. Please review the full documentation detailing financial compensation disclosures and disclaimers the article is subject to. [ https://justpaste.it/ch2qt/pdf ]. Global Markets News Network is a commercial digital brand compensated to provide coverage of news and developments related to innovative companies as detailed in the full documentation and it is thus subject to conflicts of interest. Contact Details News Coverage ronald@futuremarketsresearch.com

September 19, 2024 07:45 AM Eastern Daylight Time

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