Healthcare

Addiction Biotech Cannabis Genetics Healthcare Medical Devices Pharmaceutical Science Veterinary
News Release Digital Asset Direct

Annual Giant Sequoia Lands Coalition Progress Report Highlights Significant Advances in Emergency Wildfire Recovery, Research and Restoration

Save the Redwoods League

Officials from the State of California, USDA Forest Service, National Park Service, Tule River Indian Tribe of California, Save the Redwoods League and other members of the Giant Sequoia Lands Coalition (GSLC) today announced significant progress in their work to protect the largest trees on Earth from extreme wildfires. In its 2024 progress report, the GSLC confirms coalition partners have conducted restoration activities in more than half of the world’s sequoia groves since 2022, reducing the risk of extreme wildfires and improving overall forest health. “The Giant Sequoia Lands Coalition has made remarkable progress in defending the largest trees in the world from the growing threat of extreme megafires,” said coalition Co-Chair Kevin Conway, state forests program manager for CAL FIRE. “With meticulous research we’re gaining critical insight into the changing dynamics of these fire-adapted ecosystems. Through strategic fuel reduction and other restoration efforts across thousands of acres we’re actively making forests healthier. What began as a shared commitment in the face of crisis has evolved into a deeply rooted collaboration, built on trust, expertise and a commitment to the survival of giant sequoias.” Giant sequoia ecosystems provide essential habitat for wildlife, store vast amounts of carbon, protect headwaters and water quality, support the cultural and spiritual practices of Tribal Nations and anchor a thriving outdoor recreation economy. In the past decade, approximately 20% of the world’s mature giant sequoias died from megafires, primarily during the catastrophic fires of 2020 and 2021. Years of fire exclusion, drought and increasing temperatures were the primary drivers of the severe wildfires that killed these magnificent trees. The GSLC formed in 2022 in the face of this existential crisis. 2024 Highlights from the Report: Scientific Advancements: Leading giant sequoia ecologists published new research on post-fire regeneration and the emerging threats of native bark beetles. The GSLC also launched monitoring efforts to understand the health and vulnerabilities of giant sequoias. Ongoing research and monitoring provide a scientific basis for restoration programs and inform best practices across the sequoia range. Two recent publications discuss the substantial risk of losing portions of giant sequoia groves due to high tree mortality rates and inadequate natural recovery if no intervention is taken. Innovation: In May a health inspection of the world’s largest tree, General Sherman, was organized by GSLC members and led by the National Park Service and Ancient Forest Society. Three different technologies were used in the study, and the tree was found to be in good health. Cultural Burning Returns: Members from the Tule River Indian, North Fork Mono, and Tübatulabal Tribes led two cultural burn demonstrations within a giant sequoia grove, sharing their deep knowledge and raising awareness for this important land stewardship practice. The cultural burns were held at the Alder Creek Grove in collaboration with Save the Redwoods League and other coalition members. Rapid Wildfire Response: During the Coffee Pot Fire in Tulare County in August 2024, the GSLC members mobilized swiftly to protect vulnerable groves in Sequoia National Park and neighboring lands managed by the Bureau of Land Management. Approximately 12 large sequoias were killed by the wildfire, but overall large tree losses were kept to a minimum because of the swift actions of firefighters and the GSLC. The GSLC’s restoration work in 2024 was managed by 1,652 personnel. Since 2022, the GSLC has completed 18,743 acres of restoration treatments in 44 giant sequoia groves, and 8,500 acres of treatments in forests surrounding the groves. Fire exclusion, combined with drought and rising temperatures, has resulted in a hazardous and unnatural buildup of combustible plant materials (fuels) within and surrounding the groves. Restoration work increases the wildfire resilience of the groves by reducing the amount of fuels through manual and mechanical reductions, prescribed fires and cultural burning practices. Without these efforts, the groves are susceptible to wildfires that burn with an intensity that far exceeds the historical fires that giant sequoias evolved with, fires that they need to reproduce and regenerate. More than 74,800 native trees were planted in 2024 within groves to aid in forest recovery, raising the total to more than 617,000 native trees in the last three years. Reforestation projects focus on areas that experienced uncharacteristically high wildfire intensity where seed trees have died, burned seeds were not able to develop and minimal regeneration was naturally occurring. The full report is available here. “The Giant Sequoia Lands Coalition originated in a time of crisis. Today, it is a model for collaboration, restoration, and stewardship based in science and ecocultural knowledge,” said Ben Blom, director of stewardship and restoration for Save the Redwoods League and chair of the GSLC restoration working group. “We are poised to deepen our impact across the range in 2025. We’ve accomplished a lot as a coalition, but the work is far from done. We need to keep our momentum going to protect these irreplaceable American forests at the scale they need to thrive.” “Despite significant progress, the restoration work is far from done. The threats to giant sequoias remain urgent, and restoration at the scale required demands long-term coordination, sustained funding and supportive policies,” continued Blom. The members of the Giant Sequoia Lands Coalition include: California Department of Forestry and Fire Protection (CAL FIRE), stewards of Mountain Home Demonstration State Forest California State Parks, stewards of Calaveras Big Trees State Park National Park Service, represented by Sequoia and Kings Canyon National Parks and Yosemite National Park Tulare County, stewards of Balch Park Tule River Indian Tribe of California, stewards of all or parts of five sequoia groves University of California, Berkeley, stewards of Whitaker’s Forest USDA Forest Service, represented by the Sequoia National Forest, Giant Sequoia National Monument, Sierra National Forest, and Tahoe National Forest U.S. Department of Interior, Bureau of Land Management, stewards of Case Mountain Extensive Recreation Management Area GSLC Affiliate Members: American Forests, Ancient Forest Society, Giant Sequoia National Monument Association, Save the Redwoods League (stewards of a section of the Alder Creek Grove), Sequoia Parks Conservancy, Southern Sierra Conservancy, Stanislaus National Forest, US Geological Survey—Western Ecological Research Center and Yosemite Conservancy. Note to media: Images of GSLC projects and places are available for download here. * * * About Giant Sequoia Lands Coalition The Giant Sequoia Lands Coalition (GSLC) is a landscape-scale, multi-partner collaboration dedicated to the conservation and stewardship of giant sequoia grove ecosystems. Our coalition is composed of all federal, tribal, state and local agencies and organizations that manage giant sequoia groves in public, tribal or private nonprofit ownership. Our affiliate partners include select federal and state conservation agencies, nongovernmental organization conservation groups, and academic research partners with a shared commitment to protect and steward giant sequoias and their ecosystems from emerging threats associated with climate change and the extended absence of natural, low-severity wildfire processes on the landscape. Learn more at giantsequoias.org. # # # Contact Details Landis Communications Inc. Robin Carr +1 415-766-0927 redwoods@landispr.com Company Website https://giantsequoias.org

May 13, 2025 07:55 AM Pacific Daylight Time

Image

Players Health and MaxU Partner to Power the Next Generation of Mentally Resilient Athletes

Players Health

In a bold move to redefine athlete development, Players Health and MaxU today announced a strategic partnership to bring elite-level mental skills training to youth athletes across North America. Unveiled during Mental Health Awareness Month, this strategic alliance is both timely and purpose-driven. As mental health emerges as a cornerstone of athletic excellence and personal growth, Players Health and MaxU unite around a shared mission: to empower the whole athlete with transformative mindset tools that go beyond the game. Both organizations are anchored in a bold belief—mental health and performance are vital to athlete safety, now and into the future. This partnership integrates MaxU’s groundbreaking mental performance platform directly into the Players Health ecosystem—empowering young athletes with the focus, confidence, and resilience needed to thrive in sports, school, and life. “This is more than a partnership—it’s a movement,” said Dan Greco, Co-Founder of MaxU. “Together, we’re scaling access to proven mental skills training that helps athletes navigate pressure, unlock peak performance, and build habits that last a lifetime.” With a reach spanning teams, schools, and youth organizations, the impact is immediate and scalable—creating a new blueprint for how mental wellness and performance are taught, measured, and mastered in youth sports. “Over the last several years since joining Players Health, I've been focused on creating an environment where every young athlete feels supported in every part of their journey,” said Kyle Lubrano, Chief Athlete Safety Officer of Players Health. “Mental resilience is the foundation for everything else — confidence, physical performance, and long-term success. Partnering with MaxU allows us to deliver real, lasting change for athletes and families everywhere. This allows us to provide kids with the tools to believe in themselves, thrive under pressure, and carry those skills through every stage of life.” Two missions. One movement. Grounded in purpose and fueled by innovation, this alliance between Players Health and MaxU reflects a shared belief: supporting the whole athlete—physically, mentally, and emotionally—is not just the future of youth sports. It’s the standard. Players Health is a sports technology company providing digital risk management services, reporting tools and insurance products to sports organizations to empower them to stay ahead of their ever-changing safety and compliance responsibilities. Working towards establishing the safest environment for athletes, Players Health views the health and safety of athletes as a priority in today's sports landscape. Contact Details Jackson Gaskins playershealth@hotpaperlantern.com MaxU Contact MaxU info@maxu.co Company Website https://www.playershealth.com

May 13, 2025 09:00 AM Eastern Daylight Time

News Release

Self-Therapy is Free!

The Stuttering Foundation

To mark National Stuttering Awareness Week (May 12-18), our classic book, Self-Therapy for the Stutterer, is now available as a 65-minute film from The Stuttering Foundation ( StutteringHelp.org ). It is available free to everyone through the end of National Stuttering Awareness Week by visiting our streaming video library at http://www.stutteringhelp.org/streaming and using the promotion code: NSAW25. Based on the timeless self-help book, now in its 11 th edition, by Stuttering Foundation Founder, Malcolm Fraser, this new video, Self-Therapy for Those Who Stutter, provides a powerful message to all who view it: If you stutter, you do not need to surrender helplessly to your speech difficulty because you can change the way you talk. There is no quick and easy way to tackle the problem, but with the right approach, self-therapy can be effective! Noted speech therapist, Dr. Charles Van Riper, praised this important guide and the concepts it explains: “There are always some who stutter who are unable to get professional help and others who do not seem to be able to profit from it. There are some who prefer to be their own therapist. Malcolm Fraser has provided guidance for those who must help themselves. Knowing well from his own experience as a stutterer the difficulties of self-therapy, he outlines a series of objectives and challenges that should serve as a map for the person who is lost in the dismal swamp of stuttering and wants to find a way out.” “While there are many differing opinions today about stuttering therapy, one thing is for sure, the tried and true techniques in this video have been effective for decades,” said Bob O’Brien, producer of the film. “When I first read Malcolm Fraser’s book, I was struck by how it reads like a self-training program. I knew then it needed to be made into a video, and that it would have a great impact on the audience.” Tom Sharstein, co-founder and chairman of the World Stuttering Network, demonstrated the techniques introduced by Malcom Fraser and shared his own personal experience with stuttering throughout the video. “Malcolm Fraser’s concepts are timeless, and this book changed my life,” said Sharstein. “When I was asked to be part of this project, I had to dig back many years to the dark ages of my stutter, and hopefully through this video, you'll be able to see my progression. The techniques laid out in this film will help you obtain smoother speech, if you want it.” A trusted source of information on stuttering, Stuttering Foundation materials are as close as your nearest public library. For decades, The Stuttering Foundation has made its books and videos available for free to public libraries across the country. Today, through the generosity of benefactors, more than 16,000 libraries shelve these materials. Public libraries can request the DVD free of charge by submitting the updated request form. About the Stuttering Foundation Malcolm Fraser, a successful businessman who struggled with stuttering, established the nonprofit Stuttering Foundation in 1947 and endowed it throughout his lifetime. The Foundation provides free online resources at StutteringHelp.org for people who stutter and their families, as well as support for research into the causes of stuttering. Contact Details The Stuttering Foundation Greg Wilson +1 571-239-7474 gregwilsonpr@gmail.com

May 08, 2025 09:11 AM Eastern Daylight Time

PowerPollen Receives Foundational Patent for Groundbreaking Pollen Storage Methodology

PowerPollen

PowerPollen, an agtech company improving crop pollination for increased agricultural productivity and profitability, has received U.S. Patent 12,245,587 for its groundbreaking process of using solid particulates blended with fresh pollen grains to protect pollen’s viability during storage. As the industry leader in commercial scale pollen collection, application and storage, PowerPollen’s IP strategy has been a key part of protecting their innovation while rapidly scaling to support global seed companies and farmers since the company was founded in 2015. PowerPollen collects, preserves and applies pollen to corn, wheat, rice, and other important crops, eliminating the previously required dependency on natural pollen shedding to pollinate female plants. This process enables the ability to more reliably and cost-effectively produce high-quality seed farmers plant for crops. Corn, rice, wheat and barley rank as the top four grain crops grown globally. This patent is part of a one-of-a-kind portfolio of intellectual property PowerPollen has secured in their pursuit to increase the productivity, profitability and sustainability of modern agricultural practices. “Our initial key discoveries more than a decade ago – and our ongoing innovation since – has enabled PowerPollen to scale our unique pollination tech stack of collection, storage and application to commercial levels in agriculture—helping farmers and seed production partners increase yields without increasing other inputs,” said Jason Cope, Chief Intellectual Property Officer, PowerPollen. “Our discoveries changed the previously held notion that row crop pollen was not capable of being stored for any duration. The ripple effect can clearly be seen by the consistent yield improvements in fields that PowerPollen has treated with stored pollen.” Achieving Production and Sustainability in Modern Agricultural Practices In 2015, PowerPollen began looking for ways to improve in-field crop pollination by collecting pollen and storing it for targeted application. In their discovery process, the greatest problem they encountered was that pollen tends to form large clumps when stored, which results in a rapid decline in pollen health. “We theorized that when a pollen grain dies, its walls lose integrity and the contents of the dead cell leak out, contacting other pollen grains in the batch being stored,” Cope said. “This causes adjacent pollen grains to die, resulting in the large clumps of dead pollen cells.” PowerPollen created a unique, cost-effective production process that blends fresh pollen with different materials that separate the live pollen grains from each other. This now patented process prevents the live pollen grains from contacting any material leaked from dead pollen grains, thus dramatically extending and prolonging the pollen’s viability. Today, PowerPollen holds the most patents for pollination-based technology, crop application and related innovations, based on over a decade of intellectual data and discovery and more than eight years of commercial field data and ongoing innovation. Because of its novel technology and the founders’ understanding of marketplace realities, IP strategy has been a critical part of the business to usher in the best technology advancements for customers. Patent Reinforces PowerPollen's Leadership in Pollination Technology for Agriculture “Seed crop producers today use incredibly innovative breeding techniques yet risk it all with pollination methods that haven’t changed for generations,” Cope said. “With this patent claim, we continue to execute our IP strategy focused on the foundational building blocks of pollination-enabling technologies – and advancing this innovation across crops and geographies at the pace, scale and reliability critical to advancing higher-yield and climate-resilient food production.” Seed industry partners already look to PowerPollen’s ability to practice on-demand pollination even within fields that are planted in the normal male to female row ratio. Pollination efficiency is the key rate limiting factor for yield and kernel quality. Further, producers can improve their seed purity by intentionally applying quantities of desirable pollen, which out competes undesirable pollen. By ensuring yield, quality and purity are all maximized, PowerPollen can generate significantly more value per acre. PowerPollen’s technology will be used on thousands of acres again this season across the U.S., with expansion planned globally. Customers interested in a demo or learning more can contact PowerPollen.com. PowerPollen offers a breakthrough, scalable technology to collect, preserve and apply pollen on-demand to help improve the productivity, profitability and sustainability of modern farming practices. Following multiple seasons of year-round field trials, PowerPollen’s patented pollination technology increases yield and improves the quality of commercial hybrid corn seed production. The company has applied its technology across thousands of commercial acres over the past several years. PowerPollen is headquartered in Iowa with additional research operations in Puerto Rico and Texas. Learn more about how PowerPollen’s on-demand pollination technology works at www.powerpollen.com. Contact Details AgTech PR Jennifer Goldston jennifer@agtechpr.com Company Website https://powerpollen.com

May 06, 2025 08:30 AM Central Daylight Time

Image

Nuvectis Pharma's NXP900: Could This Revolutionary Cancer "Inactivator" Transform Oncology Treatment?

Global Markets News

Investors seeking the next breakthrough in precision oncology may want to take note of Nuvectis Pharma (NASDAQ: NVCT)*, a clinical-stage biopharmaceutical company developing, among other candidates, NXP900 - which a a new analysis is describing not merely as a cancer inhibitor, but a complete cancer pathway "inactivator." The new analysis, published on notable investment newsletter “ Truffle Pigs ”, provided a comprehensive review of Nuvectis Pharma’s NXP900. Beyond Traditional Inhibition According to the Truffle Pigs blog, NXP900 represents something entirely new in cancer treatment. Unlike traditional kinase inhibitors that merely slow cancer signaling, NXP900 is characterized as the "first SRC kinase inactivator" - a distinction that could prove crucial in the fight against resistant cancers. The analysis highlights that NXP900 functions as a "type 1.5 inhibitor" that locks the SRC kinase in its inactive state, effectively shutting down all cancer signaling pathways and keeping them disabled between doses. This complete inactivation mechanism potentially offers a significant leap beyond current therapies. Promising Clinical Data Recent data presented at the 2025 American Association for Cancer Research (AACR) meeting appears to support this thesis. According to the analysis, NXP900 demonstrated: Perhaps most intriguing were results showing that when combined with AstraZeneca's blockbuster drug osimertinib (Tagrisso), NXP900 demonstrated significant tumor regression and extended tumor control even after treatment ended - suggesting potential for durable responses or even complete responses in certain patients. Dual Market Opportunity The analysis notes two major market opportunities for NXP900: Single-agent therapy for SRC/YES1-driven tumors, potentially addressing approximately 20,000 lung cancer patients annually Combination therapy for overcoming acquired resistance to targeted drugs like osimertinib (EGFR) or lorlatinib (ALK), potentially addressing up to 70,000 non-small cell lung cancer patients annually While established companies like AstraZeneca generate nearly $7 billion annually from Tagrisso targeting approximately 20,000 new EGFR-mutated patients each year, Truffle Pigs' analysis suggests NXP900's broader applicability could potentially drive peak sales of $12-15 billion across various cancer indications. Investor Perspective With only 23 million shares outstanding and a current market cap of 219 million, Nuvectis represents a high-risk, high-reward opportunity typical of early-stage biotech. The company recently raised capital through a public offering of common stock, extending its cash runway into 2027 on what many would consider impressive terms given the market backdrop. Phase 1b trials targeting biomarker-selected cancers are expected to commence shortly, with potential clinical response data anticipated later this year.Notably, the original blog highlighted that that while the author held a position in Nuvectis Pharma (NASDAQ: NVCT), he was not compensated to write or publish the content. In other words, one might say that the author has “skin in the game”. As with all development-stage biotechnology companies, significant risks remain. analysis appropriately notes that as with all companies in the field - regulatory approval hurdles, high clinical failure rates, capital intensity, potential market competition, uncertain revenue streams, and broader economic factors all present considerable risks that investors should take into account when conducting their due dilligence. The full Truffle Pigs Blog post is available here: https://trufflepigs.substack.com/p/nuvectis-pharmas-nxp900-the-first Recent News From Nuvectis Pharma Nuvectis Pharma Provides Poster Presentation Highlights for NXP900 from the 2025 AACR Meeting Nuvectis Pharma Announces Upcoming Presentations for NXP900 at the 2025 American Association for Cancer Research Meeting Nuvectis Pharma Announces a New Publication of a Research Study Demonstrating that the Combination of NXP900 and EGFR Inhibitors Improves the Efficacy of the EGFR Inhibitors in Preclinical Models of EGFR Mutated NSCLC Legal Disclaimer & Disclosure: Nothing in this report constitutes financial or investment advice, nor does it represent an offer to buy or sell securities. This alert is published by Wall Street Wire™, a promotional content network and platform serving issuers around the globa. The operators of Wall Street Wire are not registered brokers, dealers, or investment advisers. This distribution is paid promotional content related to Nuvectis Pharma and was produced as part of their paid subscription to Wall Street Wire. This report has not been reviewed or approved by Nuvectis Pharma prior to publication. Please review the full disclaimers and compensation disclosures here: redditwire.com/terms. Readers are advised to refer to the full original blog post mentioned in the report and the disclosures it may be subject to. Contact Details WALL STREET WIRE Editorial Desk media.globalmarkets@gmail.com

May 05, 2025 01:59 PM Eastern Daylight Time

Nutriband Inc (NASDAQ: NTRB) Solution To Fentanyl Abuse Could Translate To $200 Million In Peak Revenue

NTRB

Nutriband Inc. (NASDAQ:NTRB) is a pharmaceutical company with a specific focus on developing a portfolio of transdermal pharmaceutical products. The company’s lead product under development is AVERSA™ Fentanyl, which is on track to becoming the first-ever abuse-deterrent transdermal fentanyl patch. AVERSA Fentanyl is currently pursuing a 505(b)(2) registration pathway, which should make it eligible for a more expedited review. For context, AVERSA is Nutriband’s proprietary technology that can be incorporated into any transdermal patch to prevent the abuse, misuse, diversion, and accidental exposure of drugs with the potential for abuse, like opioids. What makes AVERSA unique is its aversive agent coating, which leverages taste aversion to deter oral abuse and accidental exposure to transdermal opioid patch products. More than 70% of fentanyl patch abusers choose oral routes to abuse, so taste aversion addresses primary routes of abuse. That means AVERSA technology has the potential to improve the safety profile of transdermal drugs susceptible to abuse, such as fentanyl, while making sure that these drugs remain accessible to those patients who really need them. In one of the company’s recent major corporate milestones, Nutriband announced that it had received notification that its patent had been granted in Macao, which protects its AVERSA abuse-deterrent transdermal technology. The technology is now covered by a broad international intellectual property portfolio with patents issued in 46 countries, including the United States, Europe, Japan, Korea, Russia, China, Canada, Mexico, and Australia, as well as two regions of China: Hong Kong and Macao. Interestingly, the company hasn't been structured to follow the typical biotech standard when it comes to time and cost. The company already has two revenue-generating subsidiaries, 4P Therapeutics and Pocono Pharmaceutical, along with Active Intelligence, which specializes in sports recovery products. Nutriband’s revenues keep its development burn at a minimum. The company also owns its manufacturing and clinical development capabilities, which significantly reduces its costs for AVERSA and other technologies. Most notably, Nutriband partnered with Kindeva Drug Delivery to develop AVERSA Fentanyl, which combines Nutriband’s AVERSA abuse-deterrent technology with Kindeva’s FDA-approved fentanyl patch. Kindeva Drug Delivery is a leading global contract development and manufacturing organization (CDMO) that has a rich history in pharmaceutical innovation and manufactures millions of transdermal patches distributed worldwide. This strong partnership for AVERSA Fentanyl’s commercial development has led to significant progress in the abuse-deterrent patch’s development and manufacturing. Recently the two companies revised their agreement to formalize their exclusive product development partnership and long-term commitment based on shared development costs in exchange for milestone payments. At the same time, Nutriband revealed that it had signed an Associate Partnership agreement with Charlotte FC, which would be instrumental in helping build visibility for its brands, such as AI Tape. Management noted, “We are very excited to partner with an organization such as Charlotte FC as an Associate Partner. Manufacturing many of our products locally in the Charlotte region through our Pocono subsidiary makes this relationship special.’’ AVERSA’s addressable market is huge, depending on how you look at it. For instance, accidental fentanyl misuse is a growing problem, as illustrated by a recent report that revealed there had been 32 cases of accidental fentanyl exposure, which occurred, resulting in 12 deaths and dozens of hospitalizations, mostly involving young children. This is where the technology comes into play, as it significantly reduces the likelihood of accidental exposure to fentanyl for children. Furthermore, AVERSA Fentanyl is well aligned with the FDA’s Opioids Action Plan mission to expand access to abuse-deterrent formulations (ADFs) and to reduce the risks of misuse not just by the patient but also by other persons who obtain opioids. Upon approval of AVERSA fentanyl, the company expects that the FDA will consider requiring all fentanyl patches to be abuse deterrent, as was required for all oxycontin generics, which could potentially translate to more market share. To put the opportunity here into better context, consider this. According to Health Advances’ assessment, once approved by the FDA, AVERSA Fentanyl is expected to reach peak annual sales of about $200 million. The company believes that conservative pricing will be a key component of capturing and maintaining market share in addition to real-world data and marketing. According to the Health Advances’ report on AVERSA Fentanyl, Nutriband can expect to comfortably charge a 20% premium versus generics while maintaining insurance coverage and support, ideally capturing the market as the safest fentanyl patch in its class. Disclaimers: RazorPitch Inc. "RazorPitch" is not operated by a licensed broker, a dealer, or a registered investment adviser. This content is for informational purposes only and is not intended to be investment advice. The Private Securities Litigation Reform Act of 1995 provides investors a safe harbor in regard to forward-looking statements. Any statements that express or involve discussions with respect to predictions, expectations, beliefs, plans, projections, objectives, goals, assumptions, or future events or performances are not statements of historical fact and may be forward-looking statements. Forward-looking statements are based on expectations, estimates, and projections at the time the statements are made that involve a number of risks and uncertainties that could cause actual results or events to differ materially from those presently anticipated. Forward-looking statements in this action may be identified through the use of words such as projects, foresee, expects, will, anticipates, estimates, believes, understands, or that by statements indicating certain actions & quote; may, could, or might occur. Understand there is no guarantee past performance will be indicative of future results. Investing in micro-cap and growth securities is highly speculative and carries an extremely high degree of risk. It is possible that an investor's investment may be lost or impaired due to the speculative nature of the companies profiled. RazorPitch has been retained and compensated by Awareness Consulting LLC to assist in the production and distribution of this content. RazorPitch is responsible for the production and distribution of this content. It should be expressly understood that under no circumstances does any information published herein represent a recommendation to buy or sell a security. This content is for informational purposes only; you should not construe any such information or other material as legal, tax, investment, financial, or other advice. Nothing contained in this article constitutes a solicitation, recommendation, endorsement, or offer by RazorPitch or any third-party service provider to buy or sell any securities or other financial instruments. All content in this article is information of a general nature and does not address the circumstances of any particular individual or entity. Nothing in this article constitutes professional and/or financial advice, nor does any information in the article constitute a comprehensive or complete statement of the matters discussed or the law relating thereto. RazorPitch is not a fiduciary by virtue of any persons use of or access to this content. Contact Details RazorPitch Mark McKelvie +1 585-301-7700 mark@razorpitch.com Company Website http://razorpitch.com

April 30, 2025 07:00 AM Eastern Daylight Time

NAVEX One: Supporting HIPAA Compliance with Integrated Risk and Compliance Content

NAVEX Global

NAVEX, the global leader in integrated risk and compliance management solutions, offers healthcare organizations the tools they need to meet rigorous data privacy and security requirements. As the regulatory environment grows increasingly complex, NAVEX announces that NAVEX One now delivers centralized policy management, employee training, and risk assessment solutions aligned with the Health Insurance Portability and Accountability Act (HIPAA) enabling simplified compliance. HIPAA establishes national standards to safeguard sensitive patient health information. To avoid costly penalties and protect patient trust, covered entities must adopt comprehensive administrative, physical, and technical safeguards. NAVEX One has long supported these efforts, offering content and capabilities that streamline compliance and strengthen privacy and security programs. “HIPAA compliance is a cornerstone of trust in healthcare. Organizations need a partner that not only helps them check the boxes but also actively supports their broader privacy and risk mitigation goals,” said A.G. Lambert, Chief Product Officer at NAVEX. “NAVEX One equips healthcare compliance professionals with the tools to develop sustainable, defensible programs that protect patient data and reduce regulatory risk.” NAVEX One empowers healthcare organizations to: Centralize and maintain privacy and security policies aligned to HIPAA. Train employees on HIPAA fundamentals and emerging risks. Assess risk and implement appropriate safeguards. Prepare for audits and investigations with robust documentation. Demonstrate ongoing compliance with automated tracking and reporting. By delivering these capabilities in a unified platform, NAVEX One streamlines HIPAA compliance, reduces administrative burden, and supports a proactive, organization-wide approach to privacy and risk management. “HIPAA requirements touch every part of an organization—from workforce training to incident reporting,” said Kyle Martin, Vice President of Risk Governance at NAVEX. “NAVEX One brings it all together in one auditable platform, giving healthcare leaders confidence they’re meeting requirements while building a strong company culture.” Learn more about NAVEX One HIPAA compliance software. NAVEX, the global leader in risk and compliance solutions, is trusted by thousands of organizations to strengthen compliance and proactively manage risk. Through the NAVEX One platform and unparalleled industry data and benchmarks, organizations are empowered to maximize the potential of their compliance and risk programs. Based in Lake Oswego, OR, with a global presence, NAVEX continues to shape the future of governance, risk and compliance. Visit our blog or follow us on LinkedIn, Facebook, and YouTube. Contact Details Navex Global scott.levesque@navex.com Company Website https://navex.com

April 24, 2025 01:22 PM Eastern Daylight Time

NeuroSense Therapeutics is on Verge of Potential Blockbuster Pharma Deal as ALS Drug Shows 58% Survival Improvement

Global Markets News

NeuroSense Therapeutics (NASDAQ: NRSN)* is in active discussions with a global pharmaceutical giant for what CEO Alon Ben-Noon calls a potentially "transformative" partnership that could catapult the company's groundbreaking ALS therapy toward commercialization, according to a shareholder letter released today. The binding term sheet announced in December has progressed to advanced discussions for a "multinational partnership" that could deliver significant upfront capital and fully fund the upcoming Phase 3 trial. While initially expected to close in Q1, the complex deal's extended timeline suggests substantial terms are being negotiated, with Ben-Noon expressing optimism about an agreement that would mark "a true inflection point" for the company. Previous neurodegenerative disease partnerships have generated substantial value for biotech companies. GSK's 2021 deal with Alector included $700 million upfront and up to $1.5 billion in milestone payments, while Biogen's 2020 Denali partnership involved $560 million upfront with $1.125 billion in potential milestones. In 2024, Eli Lilly licensed QurAlis's preclinical ALS therapy for $45 million upfront plus up to $577 million in milestones—highlighting the pharmaceutical industry's willingness to invest heavily in promising neurological treatments. Investors have compelling reasons to watch NeuroSense closely as multiple catalysts approach. PrimeC, the company's novel ALS treatment, delivered remarkable Phase 2b results showing a 33% slowing of disease progression (p=0.007) and an impressive 58% improvement in survival rates compared to placebo. These potentially game-changing outcomes position PrimeC as one of the most promising ALS therapies in development. The company's dual-track commercialization strategy adds near-term revenue potential to its long-term pipeline value. While advancing toward a global Phase 3 trial set to begin in H2 2025, NeuroSense is simultaneously pursuing fast-track approval in Canada through a special regulatory pathway designed for life-threatening conditions with limited treatment options. Commercial forecasts project potential Canadian sales of $100-150 million annually—potentially providing significant revenue while the larger global program advances. Recent scientific validation came this month at the American Academy of Neurology Annual Meeting, where distinguished neurologists presented biomarker data confirming PrimeC's mechanism of action in targeting multiple disease pathways simultaneously. PrimeC's approach combines two FDA-approved drugs (ciprofloxacin and celecoxib) in a novel formulation designed to attack ALS through multiple pathways—inflammation, iron accumulation, and RNA regulation—giving it potential advantages over single-target therapies. The drug has received coveted Orphan Drug Designation from both US and European regulators. The ALS treatment landscape represents a significant commercial opportunity, with over 30,000 patients in the US and Europe and approximately 5,000 new diagnoses annually in the US alone. With limited effective treatments currently available, successful therapies command premium pricing and substantial market share. Upcoming catalysts include Canadian regulatory progress, potential partnership announcement, and Phase 3 initiation in the second half of 2025—each representing potential value-driving events for shareholders. For investors seeking exposure to late-stage neurodegenerative disease treatments with multiple near-term catalysts, NeuroSense's progress on both the pharmaceutical partnership and regulatory fronts presents a compelling opportunity to watch closely in the coming months. Recent News Highlights from NeuroSense NeuroSense Therapeutics Releases Letter to Shareholders Outlining Clinical Progress, Regulatory Strategy, and Partnership Update NeuroSense Therapeutics Announces Transformative Phase 2b MicroRNA Data, Highlighting PrimeC's Promise as a Disease-Modifying ALS Treatment *Disclaimer: This article was written and published by Wall Street Wire™, a promotional content and distribution brand and network. Nothing in this article constitutes financial or investment advice, nor does it represent an offer to buy or sell securities. The operators of Wall Street Wire network are not registered brokers, dealers, or investment advisers. This article contains and is a form of paid promotional content related to NeuroSense Therapeutics and was produced as part of their paid subscription to Wall Street Wire. This article has not been reviewed or approved by NeuroSense Therapeutics prior to publication. The information in this article is based on publicly available news reports and filings which have not been independently verified by us. Please review the full disclaimers and compensation disclosures here: redditwire.com/terms. Contact Details Wall Street Wire | Coverage Desk media.globalmarkets@gmail.com

April 24, 2025 10:36 AM Eastern Daylight Time

EDGE Boost Announces Responsible Gaming Partnership with Birches Health

EDGE Boost

EDGE Boost by EDGE Markets, one of the first debit card products designed specifically to support responsible gaming., today announced its partnership with Birches Health, a behavioral healthcare organization specializing in gambling disorder prevention and treatment. This partnership signifies yet another layer of protection for those gambling using EDGE Boost, a debit card built for more responsible gaming activities. Through the partnership, Birches Health will provide Responsible Gambling content on the EDGE Boost app and website, prompting all users to make safe and responsible decisions while gambling. Additionally, direct links to the Birches Health website and immediate access to clinicians will be just a few clicks away from the EDGE Boost app. Birches Health will use idPair technology to anonymize EDGE Boost user data for analysis and input for responsible gambling research and technology. "Our mission has always been to provide a safer and more responsible environment for users to engage with gambling,” said Seni Thomas, Founder and CEO of EDGE Boost. “Partnering with Birches Health allows us to take that commitment further, and provide immediate access to expert resources and education at the moments our users need them.” EDGE Boost redefines responsible gaming with a dedicated debit card and bank account, allowing bettors to separate their gaming transactions from everyday finances. By providing a clear, consolidated view of their betting bankroll, EDGE Boost empowers users to make more informed financial decisions. “At Birches Health, we share the same vision as the EDGE Boost team: make the gaming experience all around safer for those who partake,” said Elliott Rapaport, Founder of Birches Health. “Treatment options and educational content are now easily accessible to anyone using EDGE Boost. We are taking steps to build a more sustainable and responsible gaming industry in the U.S.” EDGE Boost announced its official launch in March of this year, after operating in stealth mode for three months. To date, EDGE Boost has raised over $17.2 million and processed over $450 million in transactions. About EDGE Boost EDGE Boost is the responsible financial platform for smart bettors. One of the first deposit accounts built exclusively for betting-related use, held with Cross River Bank, Member FDIC, and eligible for FDIC insurance up to $250,000 per depositor*. As a neutral, third party, EDGE Boost provides financial segmentation and a holistic view to bettors for all their financial betting data, with custom tools, like personalized spending limitations and cashback incentives, available to help all bettors be more responsible. Customers experience frictionless, instant free betting that is compatible with almost any online or physical betting platform. Deposit Checking accounts are held with Cross River Bank, Member FDIC. The Edge Boost Visa Debit Card is a Visa® debit card issued by Cross River Bank, Member FDIC, pursuant to a license from Visa U.S.A. Inc. The Edge Boost Visa Debit Card is not available to all residents of U.S. territories. For further information, please see our Terms of Service and Cardholder Agreement. If you think you or someone you know may have a gambling problem, call 1-800-GAMBLER. About Birches Health Birches Health provides modern, clinician-led solutions for Responsible Gaming and Problem Gambling care covered by insurance. For more information, visit Birches Health at bircheshealth.com or email partnerships@bircheshealth.com. Contact Details Sterling Randle srandle@hotpaperlantern.com Company Website https://www.edgeboost.bet/

April 24, 2025 09:05 AM Eastern Daylight Time

1 2 3 4 5 ... 213