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Living with Myasthenia Gravis: The Rare Autoantibody Disease That Causes Muscle Weakness and Severe Fatigue

YourUpdateTV

A video accompanying this announcement is available at: https://youtu.be/-FuYn9PdBdI What would you do if you began to have symptoms of drooping eyelids and difficulty speaking? A rare and unfamiliar condition that turned to a daily struggle to chew, swallow, smile, see, or even lift your arms, legs, and neck. That is what happened to Meridith O’Connor at the age of 13 and after two long years of doctor visits, she was finally diagnosed with myasthenia gravis, also known as MG. Myasthenia gravis is a chronic autoantibody condition of the nervous system that affects muscle strength and makes everyday activities like standing, blinking, swallowing, and moving your arms challenging. MG is a highly debilitating rare disease for which there currently is no cure. As many as 60,000 Americans, and 700,000 people worldwide are living with the condition. June is Myasthenia Gravis Awareness Month, which provides an opportunity for people around the world to recognize the impact of MG. On June 26th a media tour was conducted with Meridith O’Connor, Assistant Vice President of Patient Engagement, Advocacy, and Policy for the Myasthenia Gravis Foundation of America (MGFA), and Dr. Nicholas Silvestri, an associate professor of neurology at the University at Buffalo Jacobs School of Medicine and Biomedical Sciences, to learn the latest on the disease and how it affects those living with it. Approximately 85% of people living with MG experience the more extensive form of the disease, generalized myasthenia gravis (gMG). MG affects both men and women and occurs across all ages and racial and ethnic groups. However, it most commonly impacts young adult women and older men. Diagnosis is often a long, frustrating, and painful journey for patients. This is because muscle weakness is a common symptom of many disorders, and symptoms can fluctuate. Patients often face months or years of untreated symptoms before they receive an accurate diagnosis, which is why they are often diagnosed at an older age. Despite availability of treatment options, significant unmet need persists, as up to 20% of patients do not respond to existing treatments and are left with no effective therapeutic options. Research is needed to develop new treatments for those who may not respond well and/or tolerate current therapies. FOR MORE INFORMATION VISIT: IMAGINEMYMG.COM THIS MEDIA TOUR IS BROUGHT TO YOU BY THE JANSSEN PHARMACEUTICAL COMPANIES OF JOHNSON & JOHNSON. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

June 28, 2023 10:02 AM Eastern Daylight Time

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Fresh and Fun 4th of July Party Ideas for Your Barbecue Bash

YourUpdateTV

A video accompanying this announcement is available at: https://youtu.be/8tpbMSiWRsI If you’re celebrating Independence Day this year — and statistics say you probably are — your plans most likely include food. The National Retail Federation found that 86 percent of Americans plan to do something to celebrate our country’s independence, and for 61 percent of them, it means having a cookout, barbecue, or picnic. If you are hosting, or even attending, a 4th of July get together how do you prep and plan and have fresh and fun ideas. Lifestyle Expert, Bethany Braun-Silva has you covered with great ideas for what to eat and drink and how to stay healthy during your festivities. Healthier and better for you options that will delight our guests this summer Mighty Sesame Tahini is the hugely popular maker of all-natural, high-quality Squeeze and Serve Organic Tahini made with one ingredient…the highest quality sesame seeds that are sustainably sourced. The delicious, creamy texture makes this a better for you complement to dressings mon items like on summer salads, as well as for recipes, dips,meats and veggies and your favorite wraps and sandwiches. You can drizzle directly from the bottle or add it to any recipe to add 8g of plant-based protein per serving. When it comes to beverages, one that is in Bethany’s rotation is a cold-pressed juice option from Wonder Melon. Wonder Melon has the sweetness and nutritional value of watermelons, is organic, all natural and has no added sugars. It can be enjoyed right from the bottle cold, or you can enjoy as a delicious drink mix. Wonder Melon is available in three mouthwatering flavors: Watermelon Cucumber Basil, Watermelon Lemon Cayenne, and new Watermelon. Spending time outdoors and being mindful of mosquitoes The 4th of July is a holiday to be spent outdoors, so whether you’re camping, hosting a BBQ or heading to the beach, you don’t want your fun to be ruined by mosquitoes. As you’re thinking about what to buy for your vacation or party, add OFF!® Clean Feel to your list for protection from mosquitoes, ticks and biting flies. OFF!® Clean Feel is a fragrance-free, non-sticky repellent and since it’s formulated with Picaridin, it feels good on skin and won’t damage clothing. It repels mosquitoes for up to 8 hours, so you can use OFF!® Clean Feel with confidence and enjoy the holiday outdoors uninterrupted. Prevention is the best protection from mosquitoes. Bug spray is most effective when applied before mosquitoes start to bite, so you should apply it before getting to your 4th of July activity. If you are planning outdoor celebrations and travel how do you protect yourself against contaminated air Airborne Particle Blocker® is the first a nd only topical gel that prevents airborne particles from entering the nose. You apply a small amount of gel around your nasal passages, and it acts as a barrier. It blocks virus-sized particles, pollen, pollution, pet dander and dust. Available in Unscented and Cool Menthol, Naslaguard has products specific for Air Travelers, Pet Lovers, Allergy Sufferers as well as a mask spray, nasal spray and an antiseptic topical gel. The product is safe, drug-free, and non-irritating for the whole family - children, the elderly, and pregnant or nursing women. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

June 28, 2023 09:44 AM Eastern Daylight Time

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Garde Robe by UOVO Launches App and Expands into Bridal

Garde Robe by UOVO

Garde Robe by UOVO, the leading wardrobe storage and services firm established in 2001, is pleased to announce a first of its kind digital closet app as well as dedicated bridal storage services. The MyCloset app represents Garde Robe by UOVO’s commitment to providing its clients with a unique and seamless level of service. The app fuses the Garde Robe by UOVO experience with the most up to date digital technology. OrbitVu 360° cameras photograph items to be uploaded to each account for inventory and insurance purposes. Clients can then view and access their wardrobe on the app and schedule seamless, white-glove pick-up and delivery. Soon to come is the shareable MyStyle function where clients or their stylist can create and save looks based on items in their Closet. For example, a client or stylist can create looks in the app, then Garde Robe by UOVO will pull, pack and ship domestically and internationally, ideal for special occasions, change of seasons or luggage-free travel. Garde Robe by UOVO is also introducing storage services specifically dedicated to bridal to provide clients with a luxury alternative to the common practice of pushing your beloved gown to the back of your closet or storing with a local dry cleaner. Clients can have their gown, suit and accessories cleaned by a third party and prepped for storage, or Garde Robe by UOVO will assess the needs of the gown and other garments onsite to be packed in acid-free tissue in a custom size box with specific care requirements to ensure long-term preservation. “We are thrilled to introduce the My Closet app and bridal storage services to our clients,” said Brennan Lowery, General Manager, Garde Robe by UOVO. “Our goal is to always meet and exceed our clients’ needs with the most innovative technology, services, and facilities possible. The MyCloset app brings a new level of ease and access, so that clients can interact with their wardrobe and collections as if they’re shopping on a luxury e-commerce platform. Additionally, clients can choose to work directly with their Wardrobe Manager for direct, custom one-to-one service.” Like UOVO at large, Garde Robe by UOVO is more than just storage. Staffed by professionals with dedicated expertise and scholarship within the field of fashion, Garde Robe’s suite of services is on par with luxury hospitality and museum-grade archiving and preservation. All clients have access to climate-controlled storage, preservation, shipping, luggage-free travel, private viewing rooms, archiving, cataloging, mending, and cleaning at three state-of-the-art UOVO facilities that are specifically outfitted for garment and accessories care in Brooklyn, Los Angeles and Palm Beach. The announcement of these expanded services reflects an ambitious new chapter of increased resources, services, and capacity under new ownership for Garde Robe by UOVO. UOVO, which began as a boutique art storage and collection management company, has expanded its portfolio to include wine and fashion, acquiring Garde Robe in 2021, and more recently, Domaine, the premier storage, advisory and logistical firm for wine connoisseurs in the U.S. market, earlier this year. UOVO Fashion is equipped to manage the collections and wardrobes of commercial and private clients with enhancements to existing services and expansion into new offerings. Garde Robe by UOVO offers more than just wardrobe storage to create a unique experience on par with elite hospitality. Operating at a concierge level, Garde Robe by UOVO offers comprehensive stewardship of both world class brand and personal collections at state-of-the-art facilities across the U.S. Our suite of services includes maintenance, preservation, archiving, cataloging, luggage-free delivery and storage, managed through one-to-one personal relationships as well as full digital optimization. Contact Details Garde Robe by UOVO Malinda Torres Rebholz +1 917-699-6665 mtorres@ogakidigital.com Company Website https://garderobeonline.com/mycloset/

June 27, 2023 09:00 AM Eastern Daylight Time

Auto Parts 4Less Group, Inc. Unveils Significant Business Progress and Future Plans in Latest Investor Update

Auto Parts 4Less Group Inc

Auto Parts 4Less Group, Inc. (OTCQB: FLES ) (“Company”, “FLES”), the operator of AutoParts4Less.com, a specialized automotive parts marketplace, is pleased to provide an investor update. Dear Investors, I hope this message finds you well. We are excited to share our accomplishments over the past eight months, the challenges we've faced, and our plans for the future. Company Performance Overview We have made significant strides in expanding our product range. We now boast over 5.3 million products in our catalog. This is an incredible milestone, a result of our continued efforts to attract the largest and best sellers worldwide to our marketplace. Product Search and User Experience Recently, we launched Elastic Search, a significant improvement to our top-down funnel search on the platform. This enables our customers to easily find what they're looking for by simply typing it in. This project took a bit longer than expected, but we're pleased to see it live and running. We'll continue to improve this functionality in the coming months and years. Our landing page also underwent minor updates to enhance the buyer and seller experience on our site, a constant endeavor to ensure customer satisfaction. Business-To-Business Program The other major project in the works is our B2B program, which we believe is the future of our company. It will benefit sellers and buyers alike. For instance, small businesses, tire centers, and install centers across America will have the chance to register and apply to buy as a wholesale buyer, gaining access to significant savings. This feature, set to go live in the first or second week of July, is a feature we believe will revolutionize the ecosystem in which we operate. Financial and Operational Efficiency We are heavily focused on cost reduction and the economics of marketplaces, which are proven to be cost-effective business models. While we are eager to grow, we understand that growth can be costly, and we are striving to balance our growth goals with financial efficiency. This is all with a view to achieving profitability as quickly as possible. Capital Market Challenges As most investors are aware, our goal was to list on the NASDAQ. However, due to unforeseen circumstances in the capital markets, we were unsuccessful and had to withdraw our S-1 registration statement. This has put us in a challenging position in terms of raising capital. Future Funding Prospects We're actively exploring various funding options to overcome our financial challenges. Details are premature at this stage, but rest assured, we're committed to securing a robust financial future for our company and stakeholders. Updates will be shared as we make progress. Company Leadership On the leadership front, I have taken over all responsibilities for our subsidiaries and parent company after the retirement of Tim Armes, our former board chairman. I am excited and enthusiastic to lead our company forward and continue to grow our presence in the auto parts industry. Financial Reporting We acknowledge that our filings have been late and are making every effort to bring them up to date. The reality is that audits are expensive, and our limited access to capital made it difficult to initiate them on time. However, we've already invested a substantial amount in an audit, with the goal of completing it by the end of July. In conclusion, we remain dedicated to overcoming the current challenges and moving forward with our strategic plans. We're excited for what's to come and sincerely appreciate your support and patience during these times. We will keep you informed about any new developments and remain committed to ensuring our company thrives in the long run. Thank you for your continued support and belief in our vision. Christopher Davenport CEO Auto Parts 4Less Group Inc About Auto Parts 4Less Group, Inc. Auto Parts 4Less Group, Inc. (the “Company”) entered the online auto parts business in 2015, selling lift kits and other aftermarket accessories for Jeeps, Trucks, and SUVs on eBay and Amazon. In early 2020, the company began developing AutoParts4Less.com as a multi-seller enterprise-level marketplace dedicated to consolidating the $500 billion annual aftermarket automotive parts industry, including cars, trucks, boats, motorcycles, and RVs, on a single platform. AutoParts4Less.com officially launched with around 2 million parts from over 25 parts sellers in November 2022. For more information about Auto Parts 4Less Group, Inc., please visit AutoParts4LessGroup.com Forward-Looking Statements This information also contains certain forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements are identified by the use of the words “could”, “believe”, “anticipate”, “intend”, “estimate”, “expect”, “may”, “continue”, “predict”, “potential”, “possible,” “project” and similar expressions that are intended to identify forward-looking statements. All forward-looking statements speak only as of the date of this presentation. You should not place undue reliance on these forward-looking statements. Although we believe that our plans, objectives, expectations and intentions reflected in or suggested by the forward-looking statements are reasonable, we can give no assurance that these plans, objectives, expectations or intentions will be achieved. Forward-looking statements involve significant risks and uncertainties (some of which are beyond our control) and assumptions that could cause actual results to differ materially from historical experience and present expectations or projections. Actual results may differ materially from those in the forward-looking statements and the trading price for our common stock may fluctuate significantly. Forward-looking statements also are affected by the risk factors described in the Company’s filings with the U.S. Securities and Exchange Commission. Except as required by law, we undertake no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. Industry data provided herein is of no predictive value regarding the future sale of the Company’s products. No information in this press release should be construed as any indication whatsoever of the Company’s future financial results, revenues, or stock price. For more information, contact: Email: investorrelations@ap4less.com Contact Details Auto Parts 4Less Group investorrelations@ap4less.com Company Website https://www.the4lessgroup.com/

June 26, 2023 12:17 PM Eastern Daylight Time

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News Release

Tribe WOD Founders Sue Factory 14 and Razor Group, Alleging Fraud and Breach of Contract

Tribe WOD

The founders of Tribe WOD, a prominent cross-training and fitness equipment manufacturer, have filed a lawsuit against brand aggregators Factory 14 and Razor Group, citing deceit, fraud, breach of contract, unfair and deceptive trade practices, and unjust enrichment, among other offenses. The lawsuit, filed in Massachusetts Superior Court, alleges that the defendants, Factory 14 and Razor Group, failed to fulfill promises made during the acquisition of Tribe WOD. Alleged breaches of the agreement include failure to make earn-out payments as well as failing to provide access to business records – all outlined in the acquisition contract. Originating from a humble Massachusetts garage, Tribe WOD founders Alexandre Vitet and Jared Bane built their company into a $2.5 million enterprise before selling it to Factory 14, which later resold it to Razor Group. Despite promises of global expansion, enhanced marketing, access to industry experts, and potential earn-out payments, the plaintiffs argue that the defendants neglected their commitments, substantially harming the company and disregarding U.S. laws and business practices. Tribe WOD, which launched in 2019, swiftly grew to over $2.5 million in sales in just a few months, establishing strong sales channels via Amazon, Shopify, and various online platforms. This success attracted several potential buyers, with Factory 14 standing out due to its promise of multiple payments tied to Tribe WOD's annual earnings through earn-outs. The lawsuit contends that shortly after the acquisition, Factory 14 sold the assets of Tribe WOD to Razor Group, bypassing an anti-assignment provision in the original agreement. It is alleged that Factory 14 knowingly withheld information regarding this potential transaction from the plaintiffs. According to the lawsuit, Vitet and Bane had doubled revenue year-over-year and had expected to, at a minimum, match that. The lawsuit states that based on the promises made during the courtship and due diligence phase, there were immediate red flags after signing the acquisition agreement, and the situation quickly spiraled downward. Moreover, the complaint asserts that both Factory 14 and Razor Group systematically dismantled Tribe WOD, dismissing in-house creative content specialists and neglecting basic operational necessities. According to the lawsuit, Factory 14 and Razor Group failed to comply with federal and state tax, wage, and import laws and otherwise mismanaged the business financially. The lawsuit also states that the defendants had no U.S. bank account or credit card and were unable to obtain either and thus were unable to pay any of the company’s bills. The lawsuit alleges that the failure to pay basic bills led to lost revenue and the ability to serve existing customers or expand to new markets. The plaintiffs claim that their consulting agreements were prematurely terminated and allege that income from Tribe WOD was siphoned off to other businesses. The lawsuit alleges that Factory 14 and Razor Group essentially turned a thriving brand built by the founders with a rabid customer following into an Amazon seller with no identity, and loaded with unnecessary fees. The lawsuit seeks compensatory and multiple damages and injunctive relief, compelling the defendants to provide accurate and complete financial data. Interestingly, Razor Group faces a similar lawsuit in Texas, as it is being sued by the founders of Kettlebell Kings in a case with similar allegations. On its website, Razor Group states that it is trusted by leading investors Blackrock, Victory Park Capital, and Fortress among others. The Tribe WOD lawsuit was filed in Massachusetts Superior Court by Garage Sweat, LLC f/k/a Tribe Wod, LLC, Jared Bane, and Alexandre Vitet against Factory 14 UK Acquisition IV, Ltd., Razor Group GMBH, and Razor Group USA, LLC. This case has been accepted into and will be litigated in the Business Litigation Session, a business-focused sub-department of the Massachusetts Superior Court sited in Boston, Suffolk County, Massachusetts. The lawsuit can be downloaded here and at LawsuitPressRelease.com. -end- Source: Garage Sweat, LLC f/k/a Tribe WOD, LLC Contact Details LawsuitPressRelease.com John P. David +1 888-859-6637 john@LawsuitPressRelease.com

June 26, 2023 11:01 AM Eastern Daylight Time

Spiceology and Over-The-Fire-Cooking Expert Derek Wolf Expand Line of Beer-Infused Spice Blends

Spiceology

Spiceology, the fast-growing spice company known for its innovative signature blends, has once again teamed up with over-the-fire-cooking expert and social media phenomenon, Derek Wolf ( @overthefirecooking ), to create new beer-infused barbeque blends. Packaged in the fan-favorite resealable beer cans, the Spiceology x Derek Wolf Beer-Infused Rub Collection now includes a total of ten flavor-packed rubs, all infused with perfectly paired beers. Now available for purchase, this new four-pack takes consumers on a road trip around the United States to celebrate some of Wolf’s favorite styles of barbeque, including odes to Memphis, East Carolina and West Texas. “Since first launching the beer-infused six-pack with Spiceology back in 2020, we both knew we wanted to expand the beer can line,” said Derek Wolf, Over The Fire Cooking. “Beer and barbeque have always gone together, and these blends offer new ways to experiment with those flavors. For these new blends, we specifically formulated each one with a protein in mind.” These beer-infused blends can be purchased as a four-pack or as individual cans, with plastic lids included: Sticky Bourbon Brown Ale ($14.95): Memphis-style with burnt sugar sweetness, bourbon notes, and a tiny amount of heat for balance. The blend is designed for pork but is also ideal for baked beans, sauces, grilled veggies, and compound butter. Sweet Carolina Blonde ($14.95): Inspired by eastern Carolina’s Mop Sauce, this beer-infused blend packs tang, sweet and heat all in one. Designed for pork and poultry, this blend also works for chicken, seafood, pasta, rice, and marinades. Smoked Garlic Jalapeño Lager ($14.95): Inspired by West Texas’ love of chile-based heat. This beer-infused flavor twist on a classic salt and pepper blend is made for beef, but works perfectly with pasta salad, dressings, marinades, roasted veggies, and more. Big Bad BBQ Ale ($14.95): An all-purpose BBQ blend with all of Derek’s favorite flavor profiles. This blend is made for anything and everything, especially smash burgers, beef, chicken, pork, vegetables, and seafood. “The original six-pack of beer-infused blends we formulated with Derek quickly became one of our most popular products and gift sets,” said Chef Tony Reed, Executive Director of Culinary. “For this round, Derek wanted classic BBQ rubs with his personal twist, and the addition of ingredients like cinnamon, cocoa, and of course, beer, brought these classic-style blends to the next level.” The blends can be found on Spiceology.com and are available in individual beer cans or as a set of all four. For more information, see here. ABOUT SPICEOLOGY Founded in 2013, Spiceology is on a mission to inspire experimentation and share in the joy of cooking and eating. The chef-owned and operated spice company’s ‘Periodic Table of Flavor’ spotlights innovative blends and over 300 ingredients that are ground fresh and shipped fresh. With Signature Blends like Greek Freak and Smoky Honey Habanero that have become pantry and counter staples in both professional and home cook kitchens around the world, Spiceology is at the heart of the kitchen for all who love food. Spiceology‘s ingredients and blends can be found in the aisles of retailers large and small, in the pantries of hundreds of thousands of home cooks, and in the kitchens of some of the world’s greatest chefs. Contact Details Spiceology Cassidy Levine +1 908-770-7880 cassidy@spiceology.com Company Website https://spiceology.com/

June 26, 2023 08:00 AM Eastern Daylight Time

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Pancreatic Cancer Trials & New Treatments Receiving Increased Funding as Incidences of Cancer Grows

STORM Partners

FinancialNewsMedia.com News Commentary - Pancreatic cancer is one of the leading causes of cancer death globally. The increasing incidence of this cancer across the U.S. and other parts of the world is one of the factors driving the need for the drugs used in the treatment. The increase in the geriatric population is one factor driving the pancreatic cancer treatment market growth. The incidence is significantly higher in the geriatric population above 65 years of age compared to other types of cancers. The increase in the number of patients suffering from the condition has increased the demand for the drugs used in treatment. A report from Fortune Business Insights said that this factor will be driving the growth for the next several years. The report projected that the global pancreatic cancer treatment market size was valued at USD 2.48 billion in 2022 and will grow to USD 6.85 billion by 2029, exhibiting a CAGR of 15.7% during the forecast period. The report continued: “Companies engaged in manufacturing cancer drugs have increased their focus on R&D activities to develop new drugs for pancreatic cancer treatment. Additionally, the companies operating in the market have received approval from several regulatory bodies, such as the U.S. Food and Drug Administration (FDA), the Medicines and Healthcare Products Regulatory Agency (MHRA) (U.K.), among others, thereby propelling the growth of the market. Moreover, new testing technologies are being adopted by hospitals and diagnostic centers to diagnose cancer. The increase in the diagnosis rates is driving the demand for drugs, thereby providing opportunities for the players.” Active biotech and pharma companies in the markets this week include Oncolytics Biotech ® Inc. (ONCY – ONC.TSX), Sotera Health Company (NASDAQ: SHC), Centessa Pharmaceuticals plc (NASDAQ: CNTA), Bristol Myers Squibb (NYSE: BMY), Gilead Company (NASDAQ: GILD). Fortune Business Insights continued: “Shifting the focus of key players in extensive R&D activities to develop new drugs and an increase in funding for cancer research led to the development of new drugs for treatment. Additionally, several pharmaceutical companies are involved in clinical trials to develop new drugs and explore the potential of the molecule to treat the disease. It concluded: “Thus, with the increased funding for R&D activities, companies are focused on developing new drugs, thereby contributing to the overall rise in demand for drugs for pancreatic type of cancer treatment through 2029.” Oncolytics Biotech ® Inc. (ONCY - ONC) BREAKING NEWS: Oncolytics Biotech’s® Pelareorep Selected for Inclusion in Precision PromiseSM Pivotal Phase 3 Platform Trial – Adaptive clinical trial designed to accelerate registration pathways for pancreatic cancer therapies and expected to reduce cost of a Phase 3 study for pelareorep by ~50% compared to a traditional trial If successful, new clinical study expected to support approval of pelareorep in combination with a checkpoint inhibitor, gemcitabine, and nab-paclitaxel in first-line metastatic pancreatic cancer Data presented at SITC 2022 showed a near tripling of overall response rate for pelareorep + gemcitabine + nab-paclitaxel + a PD-L1 inhibitor compared to historical control trials Oncolytics Biotech ® (trading on the NASDAQ under the Symbol ONCY and the TSX exchange under ONC) today announced pelareorep has been selected for inclusion as a new investigational treatment in Precision PromiseSM, an innovative adaptive Phase 3 clinical trial. The Precision Promise study is designed to evaluate pelareorep in combination with a checkpoint inhibitor and the chemotherapeutic agents gemcitabine and nab-paclitaxel. If successful, the clinical study is expected to support approval of the studied combination as a treatment for first-line metastatic pancreatic ductal adenocarcinoma (PDAC). Precision Promise has a primary endpoint of overall survival and can include multiple investigational treatments as well as control arms evaluating: (1) gemcitabine plus nab-paclitaxel or (2) mFOLFIRINOX. Each investigational therapy is subject to pre-specified interim analyses prior to proceeding to the registrational portion of the trial. This design, which was developed with guidance from the U.S. Food and Drug Administration, minimizes the number of participants needed to generate licensure-enabling data, thereby accelerating late-stage development by up to two years and reducing costs compared to non-platform trials. “We are delighted at being selected by the Precision Promise panel of experts,” said Dr. Matt Coffey, President, and Chief Executive Officer of Oncolytics Biotech. “Our next step is to engage with stakeholders to finalize the protocol for Precision Promise’s pelareorep-containing investigational treatment so that we can enter into this study. We are thrilled to have the opportunity to leverage Precision Promise, which we expect will allow us to reduce the time and costs needed to reach a potential approval.” Julie Fleshman, JD, MBA, President and CEO of PanCAN commented, “With a five-year survival rate of 12%, pancreatic cancer patients cannot afford to wait for new treatment options. This urgent unmet need was the driving inspiration behind the Precision Promise platform trial, which was designed specifically to identify, accelerate, and de-risk the development of promising pancreatic cancer treatments. We are thrilled to be bringing pelareorep into Precision Promise as a new investigational therapy to study against the current standard of care.” Dr. Thomas Heineman, Chief Medical Officer of Oncolytics Biotech, commented, “Prior trials in pancreatic cancer show pelareorep-based combinations outperforming historical controls on key metrics such as one and two-year survival and objective response rate. In addition, mechanistic data from these studies highlight how pelareorep’s immunologic mechanism of action allows it to synergize with chemotherapy and checkpoint inhibition in this indication. I look forward to working with the Precision Promise team of investigators to seek to confirm the therapeutic value of pelareorep in a randomized setting so that we can potentially provide pancreatic cancer patients with a new treatment option.” CONTINUED …Read this full press release and more news for ONCY at: https://www.financialnewsmedia.com/news-oncy/ Other recent breast cancer developments in the biotech industry of note include: Sotera Health Company (NASDAQ: SHC) recently announced that the opt-in process for the January 2023 settlements of ethylene oxide claims against Sterigenics in the Circuit Court of Cook County, Illinois is complete and Sterigenics has elected to proceed with the settlements. 879 of the 882 claimants eligible to participate in the settlement program have opted in. The settling claimants and Sterigenics will now request that the Circuit Court enter an order confirming that these are good-faith settlements under the Illinois Contribution Among Joint Tortfeasors Act. The settlement funds will be released from escrow for disbursement to the settling claimants ten days after the Court enters the anticipated good-faith determination and their claims against Sterigenics will subsequently be dismissed with prejudice. The lawsuits of the three claimants who opted out of the settlement will proceed to pretrial discovery pursuant to a schedule to be set by the Circuit Court. Centessa Pharmaceuticals plc (NASDAQ: CNTA), a clinical-stage pharmaceutical company that aims to discover and develop medicines that are transformational for patients, recently announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to SerpinPC, an investigational novel inhibitor of activated protein C (APC) being developed for the treatment of hemophilia B, with or without inhibitors. "We are pleased with the FDA’s decision to grant Fast Track designation for SerpinPC as we continue to advance the PRESent registrational studies for SerpinPC in hemophilia B,” said Saurabh Saha MD PhD, Chief Executive Officer of Centessa. “This designation is important recognition of SerpinPC’s novel mechanism of action and underscores the critical need for new treatment options for persons with hemophilia B. We believe SerpinPC has the potential to be a first-in-class subcutaneously administered therapy with a differentiated safety profile for persons with hemophilia B, subject to review and approval.” Bristol Myers Squibb (NYSE: BMY) announced the first disclosure of primary analysis results from two pivotal studies, TRANSCEND FL, an open-label, global, multicenter, Phase 2, single-arm study evaluating Breyanzi (lisocabtagene maraleucel; liso-cel) in patients with relapsed or refractory follicular lymphoma (FL) and the relapsed or refractory mantle cell lymphoma (MCL) cohort of TRANSCEND NHL 001, an open-label, multicenter, Phase 1, single-arm, seamless-design study evaluating Breyanzi. These data were presented in late-breaking oral presentations at the 2023 International Conference on Malignant Lymphoma (ICML) on Saturday, June 17. "With Breyanzi, we’re dedicated to delivering a CAR T cell therapy with a differentiated profile to transform outcomes for some of the most difficult-to-treat lymphomas," said Anne Kerber, senior vice president, head of Cell Therapy Development, Bristol Myers Squibb. "Based on results from TRANSCEND FL and TRANSCEND NHL 001, Breyanzi continues to demonstrate the ability to elicit significant deep and durable responses alongside a manageable safety profile, potentially addressing areas of high unmet need and reinforcing our commitment to advancing innovative solutions for the broadest array of hematologic malignancies of any CD19-directed CAR T cell therapy." Kite Pharma, Inc., a Gilead Company (NASDAQ: GILD) announced that the Marketing Authorization in Japan for Yescarta® (axicabtagene ciloleucel), a chimeric antigen receptor (CAR) T-cell therapy, has been transferred from Daiichi Sankyo Co., Ltd. to Gilead Sciences K.K., the Japan subsidiary of Gilead Sciences, Inc. This follows the announcement made by Daiichi Sankyo and Kite Pharma, Inc. in December 2022 about changes to their initial 2017 partnership whereby Daiichi Sankyo obtained the Marketing Authorization for Yescarta®. With this completion of the Marketing Authorization transfer, the sales and promotion activities of Yescarta® in Japan now will be managed by the Kite Cell Therapy Business Unit of Gilead Sciences K.K. DISCLAIMER: FN Media Group LLC (FNM), which owns and operates FinancialNewsMedia.com and MarketNewsUpdates.com, is a third party publisher and news dissemination service provider, which disseminates electronic information through multiple online media channels. FNM is NOT affiliated in any manner with any company mentioned herein. FNM and its affiliated companies are a news dissemination solutions provider and are NOT a registered broker/dealer/analyst/adviser, holds no investment licenses and may NOT sell, offer to sell or offer to buy any security. FNM's market updates, news alerts and corporate profiles are NOT a solicitation or recommendation to buy, sell or hold securities. The material in this release is intended to be strictly informational and is NEVER to be construed or interpreted as research material. All readers are strongly urged to perform research and due diligence on their own and consult a licensed financial professional before considering any level of investing in stocks. All material included herein is republished content and details which were previously disseminated by the companies mentioned in this release. FNM is not liable for any investment decisions by its readers or subscribers. Investors are cautioned that they may lose all or a portion of their investment when investing in stocks. For current services performed FNM was compensated forty nine hundred dollars for news coverage of the current press releases issued by Oncolytics Biotech ® Inc. by a non-affiliated third party. FNM HOLDS NO SHARES OF ANY COMPANY NAMED IN THIS RELEASE. This release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E the Securities Exchange Act of 1934, as amended and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. "Forward-looking statements" describe future expectations, plans, results, or strategies and are generally preceded by words such as "may", "future", "plan" or "planned", "will" or "should", "expected," "anticipates", "draft", "eventually" or "projected". You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events, or results to differ materially from those projected in the forward-looking statements, including the risks that actual results may differ materially from those projected in the forward-looking statements as a result of various factors, and other risks identified in a company's annual report on Form 10-K or 10-KSB and other filings made by such company with the Securities and Exchange Commission. You should consider these factors in evaluating the forward-looking statements included herein, and not place undue reliance on such statements. The forward-looking statements in this release are made as of the date hereof and FNM undertakes no obligation to update such statements. SOURCE Financialnewsmedia.com Contact Details Financial News Media Media Contact +1 561-325-8757 editor@financialnewsmedia.com

June 23, 2023 01:09 PM Eastern Daylight Time

Bucket List Travel Not to Be Missed. The Wonders of New Zealand: The Trip Everyone Should Experience

YourUpdateTV

A video accompanying this announcement is available at: https://youtu.be/DtFT0FSO4vc What’s on your bucket list? What adventure would you like to have or what place would you like to visit? With so many places worth traveling to, it can be hard to narrow down your top spots to visit. If your list has a location with epic national parks and stunning landscapes, inspiring culture, along with bustling nightlife and friendly locals, you might be thinking about New Zealand. The wonders of New Zealand are everywhere - the wonders of walking along the beach, hearing the waves crash, and exploring city life. The wonders are in the food that’s served, sights to be seen and the kind culture that is all around. The wonder is within the breathtaking landscape and environment the Island Nation is encapsulated within. New Zealand has no shortage of new wonders to taste! When dining in New Zealand, travelers are introduced to new senses and smells, and the experience of it all is as good as the meal. The New Zealand experience begins when you step onboard with Air New Zealand. With warm Kiwi hospitality and calming amenities, it’s a wonder to discover all its own. In fact, Air New Zealand recently refreshed their cabins to ensure restful sleep is at the heart of the travel experience. From the lighting to the seats themselves - Air New Zealand innovated from tip to tail. The Air New Zealand experience is nothing short of amazing - with friendly faces, a calming atmosphere and plenty of wine and food to choose from. On Air New Zealand, you can sleep better than you ever dreamed was possible! With more choices, like the Economy Skycouch - your personal couch in the sky! - you can stretch out and catch some Z’s allowing you to recharge before arriving in New Zealand. Visit AirNewZealand.com to book your bucket list getaway to New Zealand! Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

June 22, 2023 10:00 AM Eastern Daylight Time

Video

Backyard Projects on a Budget

YourUpdateTV

With summer officially here, homeowners around the country are looking to refresh their backyard spaces and get ready for the all of the barbecues and family parties to come. Recently, Home Expert at Angi, Mallory Micetich, participated in a nationwide satellite media tour to discuss the top projects homeowners are undertaking this summer, tips on sticking to a budget, and how to know when it’s time to call in a pro. A video accompanying this announcement is available at: https://youtu.be/RLL1KozBUO8 According to a recent Angi survey - homeowners are planning a lot of projects this year. Top projects include building raised beds, laying new sod and adding a garden feature. Many of these projects can be DIY/ weekend warrior projects - especially if you have a green thumb - be mindful of what materials you are choosing for the project and take time to assess if these are actually good DIY projects for you. If you lack the time, tools or talent to take on a project, it might end up costing you more in the long run to fix any mistakes. One great way to take on a backyard project and keep to a budget is to pick a project with high visual impact and a lot of material choices - like adding a deck or a patio. With a range of decking and patio options there is one for every budget. Don’t forget to think about ongoing maintenance for your new backyard escape - dedicating some time and budget to ongoing maintenance will help keep your new yard in shape for years to come. Want to know how to keep on budget? Start by coming up with a realistic budget. Talk to several pros in your area to make sure you get high-quality work at a price that you’re comfortable with. Once you choose your pro, be very clear about your budget. A good pro will help you choose materials that work within your budget. You should also set aside 10% of the project cost for any unexpected expenses that come up during the renovation process. For more information, visit Angi.com About Mallory Micetich Mallory Micetich is a Home Care Expert, with particular expertise in small home living and consumer protection. While currently renting in Denver, CO, she has been a homeowner, investor, landlord and renter over the last decade. She is committed to minimizing her environmental footprint and to small home living, having lived in only properties of 1,000 square feet or less. Mallory is currently the VP of Corporate Communications at Angi, where she focuses on bringing awareness to Angi and what we do every day to help homeowners love where they live. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

June 22, 2023 09:37 AM Eastern Daylight Time

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