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XA Network expands and appoints senior advisory board, as Southeast Asia digital economy races ahead

XA Network

The XA Network [the X denotes any tech firm with $1b+ valuation and the A refers to Alumni], the leading member-based investment network of executives from prominent tech firms in Southeast Asia, has today appointed an advisory board. The appointments signal the organisation's growth and reach, as the Southeast Asian digital economy proves resilient and is racing ahead at full velocity. John Wood (ex-Microsoft, Room To Read), Steve Chen (co-founder of YouTube), Maya Hari (Twitter) and David Thevenon (Balderton Capital, ex-Google) have been appointed to advisory board positions. They will work directly with the members as the organisation scales and will champion the new purpose - to be an organisation that fosters inclusive innovation for the benefit of start-ups across Southeast Asia. On his appointment, John Wood, advisory board member at XA Network commented: “I’m delighted to join this esteemed board to support and drive the ambitious community of investors. The XA Network brilliantly embodies Metcalfe's law – e.g., the value of a network rises exponentially as the number of users grows. I believe this generation of technology leaders, by working together to support the start-up ecosystem in Southeast Asia, will have an immense impact on the region. We are all very committed to the power of smart capital, intense mentoring and fuelling inclusive innovation. This approach resonates with me on many levels and I look forward to helping XA Network scale to the next level”. The XA Network is made up of 100 tech leaders from companies including Alibaba, Gojek, Grab, Google, Amazon, Netflix, YouTube amongst others. These investors offer an unmatched array of skills and counsel to their portfolio companies from engineering advice, product management, to marketing and partnership building experience. As a collective, this is embodied in their purpose to foster inclusive innovation beyond simply investing in start-ups. The XA Network exists to empower the tech community in Southeast Asia with its inclusive innovation approach. The Southeast Asia digital economy is forging new ground every year* and 2020 was no different, despite COVID-19. Over 70% of the region is now online, accounting for 400 million people (of a total population of 580 million). Digital adoption of consumer-service businesses increased as more people spent time online during lockdowns. HealthTech and EdTech based companies are earmarked to take-off in the coming years. Overall, the digital economy added USD $100 billion to the region and is poised to grow to over USD $300 billion by 2025. The XA Network portfolio businesses are making a positive impact across the region such as Indonesian startups, Sampingan who enable access to the gig economy and Bukukas who enable small businesses to digitize their operations. Meanwhile, Singapore-based mentor platform Tigerhall is connecting the world’s most successful people with young professionals. Nellie Wartoft, CEO at Tigerhall commented: "We raised $2m in 2020, it was a huge milestone for the company but we had a lot to do. The XA Network members are some of the absolute most supportive investors I've ever had on my cap table. They're never afraid of rolling up their sleeves and doing real work either, which is rare to find amongst investors. They feel much more like an extended team than just financial investors to me, and have been key to Tigerhall's success." The appointments come at an exciting time for XA Network as they achieved their first exit. Lomotif, Singapore’s video-sharing service, was acquired by a syndicate for US$125 million. The deal is said to be one of the biggest exits by a tech startup in Singapore in recent years. XA Network highlights (last 12 months) Membership base increased from 50 to 100 people in March 2021 XA Network portfolio includes 30 start-ups in a range of sectors including mobility, healthtech, foodtech, edtech, adtech, fintech, social commerce, proptech Portfolio companies have also gone on to raise $82m in follow-on capital Notes to the editor * e-Conomy SEA 2020 Report About the XA Network The XA Network [the X denotes any tech firm with $1b+ valuation and the A refers to Alumni] is an investment network comprising senior executives from prominent tech companies including Alibaba, Gojek, Grab, Google, Amazon, Netflix and Twitter amongst others. Its mission is to invest and empower early-stage companies across Southeast Asia through their inclusive innovation approach, by exposing these businesses to the wide array of skills in the network. Since 2018, they have made 30 investments and expanded their member base to 100 people. XA Network has invested in a wide variety of promising companies including Bukukas, Tigerhall, Sampingan, Neuron, and Infradigital as well as the Vertex Southeast Asia and India fund. Contact Details XA Network Bilal Mahmood +44 7714 007257 press@xanetwork.co Company Website https://xanetwork.co/

April 19, 2021 08:00 PM Eastern Daylight Time

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INTERNATIONAL SCIENCE LEADERS LAUNCH A GLOBAL PLEDGE TO TRUST SCIENCE

International Day of Light Steering Committee

Ahead of this year’s International Day of Light celebration on 16 May, the International Day of Light Steering Committee announces the launch of the Trust Science pledge, a worldwide campaign to promote support for the scientific process and to acknowledge the many benefits of science for society. Crises such as the coronavirus pandemic demonstrate the importance of scientific research and remind us how much we depend on dedicated professionals to find evidence-based solutions to global challenges. To recognize the central role played by science in society, the Trust Science pledge invites the general public to join leading scientists worldwide to affirm confidence in the process of scientific research and discovery. To date, the pledge has seen enthusiastic support worldwide with founding signatories including Nobel laureates, UNESCO L’Oréal For Women in Science prize winners, Presidents and CEOs of major scientific bodies, as well as scientists and students from more than 20 different countries. The pledge is now being shared widely to invite all interested individuals to take part. The Trust Science pledge states: “Trust in evidence-based, scientific facts is essential for providing sustainable solutions to today’s challenges. By adding my name to this declaration and pledge, I recognize the key role that scientific research and discovery plays in improving quality of life for all.” The Trust Science campaign is organized by the IEEE Photonics Society, SPIE, the international society for optics and photonics, and The Optical Society (OSA), together with the International Day of Light Steering Committee. “The events of the past year have spotlighted science’s crucial role in solving critical global problems,” said Steering Committee Chair John Dudley from the Université Bourgogne Franche-Comté in France. “This campaign will allow people around the world to join us in affirming support for science and the scientific process. We encourage all to sign, and our hope is that this will stimulate valuable discussions within families, at the workplace and in educational settings.” In the context of the International Day of Light, the campaign will also highlight a number of Champions, research leaders in broad areas of light science and technology, including solar energy, the study of cultural heritage and healthcare. To sign the pledge and to learn more, please go to https://www.trust-science.org Contacts For questions about how you can engage with the campaign, please contact: info@trust-science.org For media enquiries, please contact: pr@trust-science.org Social media: please share using #TrustScience and #LightDay2021 Social media links: Facebook; Instagram; Twitter About the International Day of Light The International Day of Light (IDL) is a worldwide initiative that provides an annual focal point for the continued appreciation of light and the role it plays in science, culture and art, education and sustainable development, and in fields as diverse as medicine, communications and energy. The International Day of Light is administered from the International Basic Science Programme (IBSP) of UNESCO by a Steering Committee that includes representatives from a broad range of international partners: the American Institute of Physics (AIP), the American Physical Society (APS), Bosca, the China International Optoelectronic Exhibition (CIOE), Chinese Optical Society (COS), the European Centres for Outreach in Photonics (ECOP), the European Photonics Industry Consortium (EPIC), the European Physical Society (EPS), the Illuminating Engineering Society (IES), the International Centre for Theoretical Physics (ICTP), the IEEE Photonics Society (IPS), the International Commission on Illumination (CIE), lightsources.org - the international network of accelerator based light sources, Light: Science and Applications, The Optical Society (OSA), Tampere University, SPIE, the International Society for Optics and Photonics, SESAME, Signify, Tampere University, Transitions, the Université de Franche-Comté and Velux. For information about the International Day of Light, please visit www.lightday.org Contacts for IDL: John Dudley and Joseph Niemela 2021 Steering Committee Chairs Email: contact@lightday.org Bethany Downer 2021 Communications Coordinator Email: contact@lightday.org Media Contact for Trust Science: pr@trust-science.org About IEEE Photonics Society The IEEE Photonics Society is the professional home for a global network of scientists, engineers and allied professionals who advance laser, optoelectronics, and photonics technology. As a technical society representing the IEEE, it is a vital part of the world’s largest technical professional organization of more than 400,000 members dedicated to advancing technology for the benefit of humanity. Through its highly cited publications, conferences, technology standards, educational activities, and humanitarian initiatives, the IEEE Photonics Society provides its members in more than 160 countries the opportunity to grow professionally and stay on the forefront of transformational breakthroughs in photonics. PhotonicsSociety.org About SPIE SPIE, the international society for optics and photonics, was founded in 1955 to advance light-based technologies. Serving more than 255,000 constituents from 183 countries, the not-for-profit society advances emerging technologies through interdisciplinary information exchange, continuing education, publications, patent precedent, and career and professional growth. SPIE annually organizes and sponsors approximately 25 major technical forums, exhibitions, and education programs in North America, Europe, Asia, and the South Pacific. In 2020, SPIE provided more than $5 million in support of education and outreach programs. www.spie.org About The Optical Society Founded in 1916, The Optical Society (OSA) is the leading professional organization for scientists, engineers, students and business leaders in light science and technology. The society serves over 432,000 customers and 22,000 members from more than 100 countries who fuel discoveries, shape real-life applications and accelerate achievements in the field. OSA provides quality research, inspired interactions and dedicated resources for its extensive global network of optics and photonics experts through world-renowned publications. For more information, visit osa.org. Contact Details pr@trust-science.org +1 703-907-0010 pr@trust-science.org

April 15, 2021 10:30 AM Eastern Daylight Time

Pocono Organics Launches One of the First Regenerative Organic Grown Full-Spectrum Hemp Product Lines

Pocono Organics

Pocono Organics, one of the largest regenerative organic farms in North America, has launched one of the first regenerative organic grown full-spectrum hemp product lines and the only to carry the globally recognized Rodale Institute logo on its products and packaging. Pocono Organics’ wellness product line includes artisanal, small-batch items including tinctures, creams, salve sticks, lip balms, massage oil, popular bath bombs as well as a pet-friendly organic tincture. These products are formulated in their own lab and are available online and carried in more than 30 retail outlets, spas, and doctors’ offices across multiple states. Pocono Organics, located atop the Pocono Mountains, uses the power of USDA certified organic full-spectrum hemp extract to deliver a broader range of wellness-promoting cannabinoids - creating the entourage effect that unlocks numerous potential health benefits through multiple cannabinoids versus relying solely on CBD. “I personally know the power of plant-based supplements,” said Ashley Walsh, Founder and President of Pocono Organics. “I was diagnosed with gastroparesis in my late ‘20s. It is a very painful and daily condition where my stomach is paralyzed and I am unable digest food normally. My doctors wanted to cut out parts of my stomach, insert feeding tubes, and put me on a regiment of pills. I took a different path including an organic diet as well as CBD-rich supplements, which became vital to how I managed my condition and are part of my daily wellness routine.” Power of Nanoparticle Technology Nanoparticle technology is used in the pharmaceutical and nutraceutical industries as a way to make products instantly bioavailable to the body and to ensure precise dosing without diminished impact through first-pass metabolism – when ingested products first go through the stomach before going to work one to two hours later. “Nanoparticle technology is a game-changer for people seeking the immediate benefits of full-spectrum hemp extract,” Walsh added. “Instant bioavailability is vital for people who want to get an accurate dose they expect. The water-soluble, nanoparticle formulation has been done for select products including one of our tinctures and all of our bath bombs. It’s not seen often in this industry because it’s hard to do and is a big investment, but the value is worth it. And, we’ve kept the price in range with traditionally formulated products. We’ll be announcing a full line of nano-particle products soon made with organic ingredients.” Power of Trust “We are focused on becoming vertically integrated which is why we have invested in our in-house formulation and packaging because it’s hard to know who to trust when it comes to high quality organic CBD products,” Walsh continued. “Our mission comes from my personal healthy journey and I want to ensure our products are accessible for all – including our pets - which make this very personal for me.” According to a study done by the University of Pennsylvania School of Medicine, nearly 70% of CBD products are mislabeled. This troubling statistic is why Pocono Organics is transparent in how and where its products are grown so that consumers can make an informed decision about products they can always trust. “Every hemp plant grown at Pocono Organics has been in our hands from hand-seeding to hand-harvesting,” said Walsh. “We hang dry our plants so that they retain higher levels of cannabinoids and terpenes – which makes a better-quality product. Each of our products include organic ingredients that you can pronounce!” Every Pocono Organics’ product has a QR code that allows consumers to review the Certificate of Analysis (COA) from an independent, third-party research lab ensuring there are no pesticides or heavy metals in any of the products. "I have been using Pocono Organics creams, both scented and unscented, on my clients in our spa and believe these to be top-quality products that actually work,” said Yvette Bertsch, Spa Director at the historic Congress Hall Resort in Cape May, NJ. “I was impressed by Ashley and how her products evolved from a deep desire and need for health, healing, and a better quality of daily living. Ashley’s products far surpassed me and my clients’ expectations for results, which is why I trust and use Pocono Organics.” “Kitchen Toke's foundation is rooted in the belief that cannabis is food and food is medicine,” said Joline Rivera, founder of Kitchen Toke. “Our collaboration with Pocono Organics very much fit that definition. It starts with their care in the regenerative farming practices through to the final products. Pocono Organics is a win/win for people and our environment, especially the honeybees!”\ The Pocono Organics line up can be found at more than 30 retail locations, including Kimberton Whole Foods, Kalahari Resorts and Conventions, Riverwards Produce Market, Local Roots NYC, Kitchen Toke online store. “I have been recommending CBD to my patients for several years,” said Dr.Peter Hunt, a practicing chiropractor in Stroudsburg, Pa. “The primary reason is its ability to allow the body to better respond to stress and reduce inflammation. The flavonoids, polyphenols, cannabinoids, and terpenes all act together to reduce inflammation and protect the central and peripheral nervous systems. I am finding that the nanotechnology is very effective for many of my patients. Pocono Organics’ partnership with Rodale Institute ensures the highest level of organic farming that you can find, thus ensuring the highest quality products that are available.” Pocono Organics is also the only company in the world to carry the renowned Rodale Institute logo on its products and packaging as a sign to consumers of the high standards and responsible farming practices used to make these items. Rodale Institute, recognized as the global leaders in regenerative organic science and research, is a strategic partner of Pocono Organics to bring the power of soil-based farming to larger audiences. Regenerative organic agricultural practices include low-till methods and zero use of chemicals and pesticides. This farming approach produces some of the cleanest and nutrient-dense crops grown on earth – making them better for consumers – while also strengthening and healing the soil in which they are grown – which is better for our planet. Click here to learn more about Pocono Organics’ regenerative organic grown full-spectrum hemp product line. About Pocono Organics Pocono Organics is a health and wellness organization with a mission to inspire people and heal the earth. The Global Center for Research, Education, and Discovery is one of the largest regenerative organic farms in North America. Located in Long Pond, Pennsylvania, Pocono Organics has more than 380 acres of farmland and 40,000 square feet of greenhouse space. Pocono Organics has a strategic partnership with Rodale Institute, the global leaders in Regenerative Organic Agriculture practices and research and is one of their largest research satellite facilities. The farm is also home to more than 250,000 honeybees that make delicious honey and help strengthen the local ecosystem. Awarded the 2019 Environmental Innovator of the Year by the Green Sports Alliance, sustainability is a hallmark of Pocono Organics. The farm draws power from a 3MW, 25-acre solar farm and reclaims rainwater from 70,000 square feet of roofs for irrigation. Pocono Organics also serves the local community through its Clean Food, Dirty Hands school education program and veterans in transition through a Veteran Farmer Training Program. In addition, the property includes an organic farmer’s market and café, and with a 56-room adjoining hotel, is an agritourism destination, and host location for annual festivals. Please visit www.PoconoOrganics.com to learn more about Pocono Organic’s mission and work. These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, or prevent any disease. Contact Details Pocono Organics Mike Mooney +1 704-361-9499 mike@poconoorganics.com Company Website https://www.poconoorganics.com/

April 14, 2021 01:05 PM Eastern Daylight Time

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Quidel Corporation Partners With the Bay Area Lyme Foundation to Heighten Public Awareness of Lyme Disease

Quidel Corporation

With Lyme disease season breaking out across the United States, Quidel Corporation announced today that it has partnered with the Bay Area Lyme (BAL) Foundation to help heighten public awareness to this alarming health condition that afflicts as many as 400,000 Americans each year. Quidel is the nation’s leading developer of rapid Lyme disease testing. As part of its collaboration, Quidel will serve as the sponsor for BAL’s series of free speaker forums that focus on research and science in the field of Lyme disease as well as Lyme disease prevention. These events provide new information on various Lyme topics in an open-discussion format, all designed to bring awareness around the Lyme disease epidemic with rapid ways to diagnose and treat it. Each of these events will feature a scientific researcher paired with a Lyme survivor sharing their inspirational story. The first in the series will be held via zoom on May 19 and will discuss the topic of “Herbal Treatments for Tick-Borne Diseases.” Speakers will include Sunjya Schweig, M.D., who has been studying, teaching and practicing integrative and functional medicine for over 25 years and is a member of the BAL’s scientific advisory board. Also participating will be Lia Gaertner, a BAL board member and the organization’s director of education and outreach. More information is available at speakerseries@bayarealyme.org. Quidel will also be a primary sponsor of BAL’s Emerging Leader Awards, which recognize both established and up-and-coming researchers who bring creative thinking to the field of Lyme disease. These grants support new and innovative projects and aim to attract aspiring new scientific talent to the field of Lyme. In addition, Quidel will sponsor the annual LymeAid Gala, the foundation’s annual benefit dinner and live concert to be held later this year. “The fact that symptoms of Lyme disease may not appear for weeks makes it all the more important that people take steps to avoid getting a tick bite, be aware of Lyme’s early warning signs, and then get tested immediately if they think they may have contracted it,” said Cheryl Miller, vice president of market development at Quidel. “That’s why we are so honored to be partnering with the Bay Area Lyme Foundation. Together, we work to heighten public awareness of the disease and advance scientific research in testing and treatment for Lyme.” Lyme disease is a bacterial infection that occurs when people are bitten by an infected deer tick. It can strike anyone at any age and can lead to a number of serious, life-threatening problems if not caught early. Leading the way in Lyme disease testing is Quidel’s innovative Sofia® 2 Lyme FIA. This test provides the patient as well as his or her physician with indicative results within 15 minutes, as opposed to days, which has historically been the norm. Performed in the privacy of a doctor’s office or local clinic, it is also the only test that can get results from a simple finger prick of blood. Quidel Corporation (Nasdaq: QDEL) is a leading manufacturer of diagnostic solutions at the point of care, delivering a continuum of rapid testing technologies that further improve the quality of health care throughout the globe. An innovator for over 40 years in the medical device industry, Quidel pioneered the first FDA-cleared point-of-care test for influenza in 1999 and was the first to market a rapid SARS-CoV-2 antigen test in the U.S. Under trusted brand names, Sofia®, Solana®, Lyra®, Triage® and QuickVue®, Quidel’s comprehensive product portfolio includes tests for a wide range of infectious diseases, cardiac and autoimmune biomarkers, as well as a host of products to detect COVID-19. With products made in America, Quidel’s mission is to provide patients with immediate and frequent access to highly accurate, affordable testing for the good of our families, our communities and the world. For more information about Quidel, visit quidel.com. Contact Details Jim Yeager +1 818-264-6812 jim@breakwhitelight.com Company Website http://Quidel.com

April 13, 2021 08:00 AM Eastern Daylight Time

Comcast RISE Awards An Additional 19 BIPOC-Owned, Small Businesses in Twin Cities with Marketing and Technology Resources and Makeovers

Comcast West Division

Comcast Corporation (NASDAQ: CMCSA) today announced the second round of Comcast RISE award recipients in the Twin Cities—19 businesses will receive consulting, media and creative production services from Effectv, the advertising sales division of Comcast Cable, or technology upgrades from Comcast Business, based on the specific needs. To date, the Twin Cities has announced 32 recipients including a diverse roster of small business, from Duck Donuts in Woodbury, The Zen Bin in Minneapolis, and The Creative Studio in St. Paul. The new Comcast RISE recipients in the Twin Cities include: AG on the Cut, St. Paul Alma Flor Ada Spanish Immersion Early Learning Academy, Woodbury Atrebla Early Learning Center, Minneapolis Big Cutz Barbershop, Columbia Heights Center for Communication & Development – KMOJ-FM, Minneapolis Cilantro Restaurant, Woodbury Cravings Wine Bar & Grille, Woodbury DFS Consultants LLC, St. Paul H & S Booking LLC, New Hope HercLÃ©on, St. Paul K & M Construction of MN LLC, Lake Elmo Lions Gym and Wellness Center, Robbinsdale Morris Services LLC, Minneapolis Premiere Staffing Group, St. Paul Queen Anna House of Fashion, Minneapolis The Black Threadist, Brooklyn Park The Pole Barn Studio LLC, Stillwater Urban Mass Media Group/BMA, Minneapolis Work of Art Barbershop & Shave, Robbinsdale Comcast RISE, which stands for “Representation, Investment, Strength and Empowerment,” focuses on Black, Indigenous, and People of Color (BIPOC)-owned, small businesses in the U.S., those hit hardest by the pandemic according to a recent study from the National Bureau of Economic Research. New applications are now open to eligible BIPOC-owned, small businesses through May 7, 2021 at www.ComcastRISE.com. “At a time when so many in our small business communities are struggling, it’s incredibly humbling to be able to give back and share our knowledge and resources with those hit hardest by the pandemic. We want to help our partners and communities rise,” said J.D. Keller, regional senior vice president, Comcast Twin Cities. “I could not be more pleased to be supporting the BIPOC community and continue this positive momentum.” “The past year has seen unprecedented challenges for our business community, especially for those small-to-medium size operations owned by BIPOC entrepreneurs,” said B Kyle, president and CEO, St. Paul Area Chamber. “That’s why we’re so pleased that Comcast is offering valuable support through Comcast RISE with marketing, advertising and technical expertise. We stand behind their efforts and encourage our local businesses to apply for this important program.” Comcast RISE provides the opportunity for BIPOC-owned, small businesses nationwide to apply for one or more of the following support focus areas: Marketing Services: The following services from Effectv, the advertising sales division of Comcast Cable, and its creative agency, Mnemonic, are designed to help recipients with their marketing and media campaigns, including: Media: A linear TV media campaign to run over a 90-day period. Creative Production: Turnkey:30 TV commercial production, plus a media strategy consultation and 90-day media placement schedule. Consulting: Advertising and marketing consultations with local Effectv marketing, research and creative teams to gain insights on how to drive business. Technology Makeovers: The state-of-the-art equipment and technology upgrade from Comcast Business includes computer equipment as well as Internet, Voice and Cybersecurity services for up to a 12-month period. (Taxes and other fees may still apply for technology makeover services.) Comcast RISE is part of a larger $100 million Diversity, Equity and Inclusion initiative that Comcast launched in 2020. About Comcast Corporation Comcast Corporation (Nasdaq: CMCSA) is a global media and technology company that connects people to moments that matter. We are principally focused on broadband, aggregation, and streaming with over 56 million customer relationships across the United States and Europe. We deliver broadband, wireless, and video through our Xfinity, Comcast Business, and Sky brands; create, distribute, and stream leading entertainment, sports, and news through Universal Filmed Entertainment Group, Universal Studio Group, Sky Studios, the NBC and Telemundo broadcast networks, multiple cable networks, Peacock, NBCUniversal News Group, NBC Sports, Sky News, and Sky Sports; and provide memorable experiences at Universal Parks and Resorts in the United States and Asia. Visit www.comcastcorporation.com for more information. About Comcast Business Comcast Business offers Ethernet, Internet, Wi-Fi, Voice, TV and Managed Enterprise Solutions to help organizations of all sizes transform their business. Powered by an advanced network, and backed by 24/7 customer support, Comcast Business is one of the largest contributors to the growth of Comcast Cable. Comcast Business is the nation’s largest cable provider to small and mid-size businesses and has emerged as a force in the Enterprise market; recognized over the last two years by leading industry associations as one of the fastest growing providers of Ethernet services. For more information, call 866-429-3085. Follow on Twitter @ComcastBusiness and on other social media networks at http://business.comcast.com/social. About Effectv Effectv, the advertising sales division of Comcast Cable, helps local, regional and national advertisers use the best of digital with the power of TV to grow their business. It provides multi-screen marketing solutions to make advertising campaigns more effective and easier to execute. Headquartered in New York with offices throughout the country, Effectv has a presence in 66 markets with nearly 35 million owned and represented subscribers. For more information, visit www.effectv.com. Contact Details Comcast Jill Hornbacher +1 651-425-1695 Jill_Hornbacher@comcast.com Comcast Dave Nyberg 651-341-6401 Dave_Nyberg@comcast.com Company Website https://twincities.comcast.com

April 08, 2021 10:00 AM Central Daylight Time

Boston Biotech, Anodyne Nanotech Advances the Hero Patch Platform by Securing $4.2M in Seed Financing

Anodyne Nanotech, Inc.

Anodyne Nanotech, Inc., a Boston-based biotechnology company developing differentiated, transdermal forms of high-value drugs, announced today that it has raised $4,200,000 to expand its Hero Patch™ platform. Lead investors were Velocity Partners, Relativity Healthcare Fund, and Big Pi Ventures. “For many years the pharmaceutical industry has envisioned, but never achieved, a transdermal patch to replace subcutaneous administration of high-value biologics,” said Lampros Kourtis, Ph.D., a Partner at Velocity. “With its solid-state porous microneedles, Anodyne looks poised to succeed where others have failed.” This new class of microneedles was invented at Tufts University and is now the core technology of the Hero Patch™ platform at Anodyne, founded by Hojat Rezaei Nejad, Konstantinos Tzortzakis, and Jake Lombardo. By incorporating solvent-free bulk drug substance directly into microscopic porosities, Anodyne can load unprecedented amounts of the drug onto each microneedle. When the microneedle penetrates into the skin, the drug dissolves in the patient’s interstitial fluid and is systemically absorbed. “With the ability to load up to 5 mg of drug per square centimeter, we can administer pharmacologically relevant doses of high-value biologic drugs like peptides and monoclonal antibodies,” said Anodyne CEO Jake Lombardo. “Our in vivo studies also show that we can achieve desired pharmacodynamic effects.” Not only does Anodyne’s technique allow for unprecedented drug loading, but also using the solid-state form of the drug substance can lead to improved stability. This promise would circumvent the need for cold-chain distribution, a critically important challenge for developing countries, with cost-saving advantages for the global biopharmaceutical industry. Mr. Lombardo added that he and others have found the Hero Patch—in placebo form—to be painless and non-irritating. Anodyne has started collaborations with pharmaceutical companies to test particular biologics on the Hero Patch platform. The company plans to conduct clinical trials to characterize the bioequivalence, safety, and tolerability of several Hero Patch products. “Modern R&D is yielding dozens of miraculous biologic drugs, but our means of administering them has scarcely improved since the 19th century,” said Michael Singer, MD, Ph.D., a director at Anodyne. “Patients don’t like getting shots. Our healthcare system would save time and money if we didn’t have to give so many shots.” “We believe we have something to offer to all who work with biologics: patients, providers, pharmacies, and pharmaceutical companies,” said Mr. Lombardo. “We would be particularly gratified if Hero Patch could be used for needle-free delivery of biologics to children.” About Anodyne Nanotech: Anodyne is a Boston-based, preclinical-stage biotech company developing differentiated, transdermal forms of high-value drugs. The company’s patent-pending porous microneedle technology provides the first practical and cost-effective platform, Hero Patch™, to deliver clinically meaningful doses of macromolecules and small molecules. For further information: www.TheHeroPatch.com Contact Details Anodyne Nanotech Jake Lombardo +1 732-503-3865 jake.lombardo@theheropatch.com Company Website https://www.theheropatch.com

April 08, 2021 05:02 AM Eastern Daylight Time

R2 Technologies Disrupts the Aesthetics Industry with Its Groundbreaking Glacial Rx™ Treatment

R2 Technologies

R2 Technologies Inc. ("R2") the leader in CryoAesthetic™ medical devices, launches Glacial Rx™, the first revolutionary in-office CryoAesthetic™ age spot removal treatment, FDA-cleared to remove benign lesions and temporarily reduce pain, swelling and inflammation. Developed by the pioneers of CoolSculpting and Fraxel, Glacial Rx is the first and only technology that uses Cryomodulation™ to improve skin appearance and freeze melanin at the source. The treatment harnesses the power of cold, using patented cooling technology, to suppress melanin production and remove unwanted dark spots. It also brightens, soothes, and renews skin for peak results and no downtime. “I am excited to partner with Glacial Rx to be among the first to offer this novel treatment in my practice,” says Board Certified Dermatologist Dr. Gregory Nikolaidis. “I believe it will be a game-changer in the category of cryoaesthetics, offering the opportunity to treat new patients who are looking for a comfortable solution to remove benign lesions.” The Glacial Rx System is an FDA Class II Device administered by trained healthcare professionals. Effective on most skin types, Glacial Rx delivers the best possible outcomes to remove age spots without the contraindications, risks, side effects or limitations associated with heat modalities. In partnership with one of the world’s fastest growing cosmeceutical skincare brands, Allies of Skin, Glacial Rx offers a curated topical regimen made with optimal active ingredient concentrations that can be provided alongside the treatment at the healthcare professional's discretion. The treatment consists of: Cool: The cold plate is applied to a spot for 15-20 seconds; no topical anesthetics or numbing agents needed. Calm: The cooling handpiece is gently moved across the face to reduce redness and puffiness, clearing the way for skin to better absorb potent topicals. Protect: Serums containing protective antioxidants and brightening agents can be applied, shielding the skin from environmental aggressors. Post-treatment take-home topical offerings, formulated with skin-beneficial plant derived actives, aid in skin recovery, accelerate skin’s desquamation process and re-epithelialization, and dramatically boost antioxidant activity to fight free radical damage. “It took us a long time to ensure that we were creating a best-in-class treatment, giving unparalleled results and superior experiences to our patients, and we are thrilled to finally bring this matchless innovation to market,” says Tim Holt, R2 Chief Executive Officer. According to a recent clinical study, 93% of spots improved at 2 months [1]; and another showed that 90% of patients said their skin was rejuvenated, brighter or more even at 1 month [2]. Launching this month in dermatology offices and med spas nationwide, Glacial Rx was named among ‘2021 Launches Doctors are Buzzing About’ by RealSelf, the leading and most trusted source to educate on cosmetic procedures. R2 is continuing to facilitate Glacial Rx system orders for practices to offer the treatment. Learn more about R2 Technologies and Glacial Rx at glacialskin.com and follow the company on LinkedIn. About R2 Technologies: Headquartered in Silicon Valley, R2 Technologies is a world leader in CryoAesthetic™ medical devices. In 2014, Pansend Life Sciences, LLC and Blossom Innovations, LLC founded R2 Technologies and licensed exclusive intellectual property from Massachusetts General Hospital. In 2019, R2 brought on another strategic partner, Huadong Medicine Co., Ltd. In close collaboration with these partners and the brand’s scientiﬁc founders and world-famous luminaries in aesthetic medicine, Drs. Rox Anderson, Dieter Manstein, and Henry Chan, R2 focuses on the development, engineering, clinical research, and commercialization of groundbreaking technologies for aesthetic providers and consumers. Since inception, R2 has raised $62 million in ﬁnancing led by a world-class team of experts within the aesthetics industry and was named winner of the 2nd Annual Aesthetics Tech Summit LaunchPad SBDC, hosted by Octane, a company committed to making resources, capital and mentorship available to tech and medtech startups. _________________________________________________________________________________________________ [1] Evaluation of the Dermal Cooling System for the Enhanced Treatment of Benign Pigmented Lesions and Common Skin Conditions - Interim Analysis - Nov 2020 - TD-0993 [2] Evaluation of a New Dermal Cryotherapy System for the Treatment of Benign Pigmented Lesions - Interim report - May 2018 - TD-0992 Contact Details Linsey Tilbor Rubin +1 732-991-5294 ltilbor@rellmc.com Company Website https://glacialskin.com/

April 07, 2021 08:17 AM Eastern Daylight Time

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How Medicaid Compliant Annuities Work by: Jennifer Lang Financial Services

Jennifer Lang Financial Services, LLC

Contact Details Jennifer Lang Financial Services, LLC. Jennifer Lang +1 877-487-8926 mail@jenniferlangfinancialservices.com Company Website https://www.jenniferlangfinancialservices.com

April 06, 2021 10:05 AM Eastern Daylight Time

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Start of Lyme Disease Season Provides Heightened Risks for Americans Wanting to Go Outdoors After a Year of COVID-19 Restrictions

Quidel Corporation

As America slowly and hopefully extricates itself from the coronavirus pandemic, another health concern lies just around the corner: the start of Lyme disease season. To complicate matters, Lyme disease is one of the distinct underlying conditions that make those afflicted more vulnerable for coronavirus complications. “The warm weather of spring and summer makes everyone want to get outdoors and never more so than this year when so many of us have spent the past 12 months hunkered down in our own homes,” says Judi Tilghman, Ph.D., vice president of technology assessment at Quidel Corporation, the nation’s leading developer of rapid Lyme disease testing. “The key is to be smart in taking steps to avoid getting a tick bite in the first place and then getting tested immediately if you think you may have contracted Lyme.” Lyme disease afflicts as many as 400,000 Americans every year and can lead to a number of serious, life-threatening problems if not caught early. The challenge is that unlike a mosquito bite where people know immediately if they have been bitten, deer ticks that may carry Lyme disease are tiny—the size of a poppy seed—and symptoms may not appear for two to six weeks. That makes it critically important that anyone who spends time outdoors in heavily wooded areas—hikers, hunters, campers—or travels to such places be particularly vigilant. Some of the basic symptoms of a Lyme infection—fever, malaise, fatigue, muscle aches and headaches—can resemble COVID-19, which, according to Dr. Tilghman, is “still another reason to get tested if you feel any of these symptoms coming on. The vast majority of patients tested are negative, so getting results quickly with Quidel’s Sofia® 2 Lyme FIA test can provide peace of mind for individuals while also allowing physicians to more rapidly pursue testing and treatment for other diseases that may be causing the patient’s symptoms.” While Dr. Tilghman acknowledges that a walk in the woods, a return to playing outdoor sports on grassy fields, or camping by a river or lake is an appealing way to relieve stress from the coronavirus lockdown, she warns that such activities do come with the risk of ticks that carry Lyme and other illnesses. For anyone who intends to spend time in wooded/grassy areas during the height of Lyme disease season, she recommends: Shower right away as ticks often remain on skin for hours before attaching themselves. Showering and using a washcloth can remove unattached ticks. Check your entire body for ticks, including low-visibility areas such as the groin, underarms and the back of your neck. If you find a tick on your body, use a pair of tweezers to pull it off very gently but firmly. Watch for early signs which may include a rash (often shaped like a bullseye), flu-like symptoms, fever, body aches, headache and fatigue. Watch for later symptoms, which could appear weeks or months after being bitten. These may include a rash on areas of your body, joint pain, neurological problems, heart problems (such as an irregular heartbeat), eye inflammation, liver inflammation (hepatitis) and severe fatigue. Get to a doctor or clinic right away, and ask to be tested if you sense you might have Lyme disease. The innovative Sofia 2 Lyme FIA test is an in-office test that provides indicative results within minutes as opposed to days, which has historically been the norm. Performed in the privacy of a doctor’s office or local clinic, it is also the only test that can get results from a simple finger prick of blood. The best solution, of course, is to not get a tick bite in the first place; and there are many precautions people can take to lessen the chance of getting bitten. Dr. Tilghman says these include: wearing long pants and shirts, a hat and gloves when in wooded areas; sticking to trails and avoid walking through low bushes and long grass; putting lavender oil or insect repellants on your legs and arms and any bare skin; and tick proofing your yard by clearing brush and leaves and mowing your lawn regularly. About Quidel Corporation Quidel Corporation (Nasdaq: QDEL) is a leading manufacturer of diagnostic solutions at the point of care, delivering a continuum of rapid testing technologies that further improve the quality of health care throughout the globe. An innovator for over 40 years in the medical device industry, Quidel pioneered the first rapid diagnostic point-of-care test for influenza in 1999 and was the first to market a rapid SARS-CoV-2 antigen test in the U.S. Under trusted brand names, Sofia®, Solana®, Lyra®, Triage® and QuickVue®, Quidel’s comprehensive product portfolio includes tests for a wide range of infectious diseases, cardiac and autoimmune biomarkers, as well as a host of products to detect COVID-19. With products made in America, Quidel’s mission is to provide patients with immediate and frequent access to highly accurate, affordable testing for the good of our families, our communities and the world. For more information about Quidel, visit quidel.com. Contact Details Jim Yeager +1 818-264-6812 jim@breakwhitelight.com Company Website http://Quidel.com

April 05, 2021 08:00 AM Eastern Daylight Time

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