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Inhibikase Therapeutics: A Novel And Promising Approach To Neurodegeneration And Oncology

TalkMarkets on IKT

Inhibikase Therapeutics ( IKT ) is a small capitalization company working in both neurology and oncology. Their principal focus is a small molecule inhibitor of c-Abl for the treatment of a number of neurodegenerative disorders with an initial focus on Parkinson’s Disease. The lead asset (IkT-148009) is a selective, brain penetrant inhibitor of c-Abl1 and Abl2/ARG. The drug is designed to minimize the toxicity commonly associated with the cancer drugs of this class, while maximizing efficacy against neurological diseases. Neurodegeneration has multiple causes, but the aggregation of misfolded proteins is often associated with these diseases and in the case of Parkinson’s Disease it is the aggregation of alpha-synuclein. Given that these aggregates are clearly associated with the disease, a common tactic to drug development is to find treatments that eliminate the protein bundles, but these approaches have generally had quite modest effects. Inhibikase approaches the disease from a different perspective in that the core issue is when those aggregates become internalized in neurons (in the case of PD). When this occurs, c-Abl triggers a cascade of responses that ultimately leads to neurodegeneration. Inhibiting c-Abl stops these reactions and saves the neurons. (The details of this approach can be seen in the recent article in Neurodegenerative Disease ). One of the difficulties of inhibiting c-Abl in neurodegenerative diseases, however, is the potential toxicity. Gleevec is a commonly used inhibitor of c-Abl in oncology, where it has an acceptable toxicity profile, but it would be too toxic for neurological indications. Developing a drug that can inhibit c-Abl in the brain but without the common toxicities is the fundamental breakthrough of IkT-148009. It is the selectivity of the inhibition that is key. The corporate presentation clearly shows a differentiated inhibition profile ( source ). This selective inhibition of IkT-148009leads to a very clean toxicity profile ( see graphic ). This safety is not simply theoretical as their phase I, Ib, and 2a trials confirm the lack of significant toxicity. There was a grand total of 14 reported adverse events among 113 treated patients and only one was moderate; the rest were mild ( see graphic ). It cannot be stressed enough that safety is absolutely crucial in neurological indications, and it seems that the design of the drug, the preclinical and early clinical results all point to low toxicity, which is exactly what you want to see from these early looks. Inhibikase currently has an ongoing double-blind enrollment trial across three doses for the treatment of Parkinson’s disease. The trial includes a 3-month treatment period followed by a 12-month open label extension. The primary endpoint is safety, which is appropriate for a dose ranging phase II trial and expectations should be a clear confirmation of the established safety profile. That being said, there is a robust set of secondary endpoints that will provide important information as to the efficacy profile. The preclinical work in a Parkinson disease animal model demonstrated a consistent efficacy where treatment lowered alpha-synuclein back to baseline levels, preserved as much as 85% of neurons, restored as much as 90% of motor function, and suppressed neuroinflammation back to near baseline levels. Obviously, a replication of those results in the phase II trial would be spectacular but a clear win would also be a confirmation of the safety profile, a strong signal of efficacy, and a clear move forward dosing level. Given that the PK profile seen in the animal models is similar to the PK shown in the phase I trials, the chosen dosing levels in the phase II trial should lead to a go forward dosing as well as a demonstration of efficacy. The company has guided to a robust set of progress in 2023, where the continued enrollment of the phase II trial is perhaps the most important. Open up to thirty-five 201 trial sites by close of 2Q23 Active screening of commercial formulation Implement 12-month open-label safety extension study into 201 trial Characterize novel compounds as follow-ons to IKT-148009 I noted earlier that Inhibikase Therapeutics is both a neurology and oncology company. In terms of oncology, the company has an improved version of Gleevec that is designed to minimize GI toxicity. This asset is undergoing a bioequivalence trial, which could accelerate the pathway to approval, but I think the key valuation inflection point will be the 201 trial in Parkinson’s disease. The 201 trial has the potential to confirm the safety profile, identify a go-forward dose, and establish efficacy. The current valuation of the company does not reflect any of that potential. It does not even properly reflect the safety profile seen in the phase I trials let alone a potential success in the 201 trial. The heavily discounted valuation provides a compelling risk/reward given the ability to establish both safety and efficacy in Parkinson’s disease let alone any progress in oncology. Originally published at TalkMarkets. More By This Author: The FTC, Amgen, And Horizon: A New Hurdle For Biotech Deal Making Or Regulatory Overreach? Coya Therapeutics: Another Success Sarepta: The AdCom Documents Enter The Discussion Disclosure: This article is part of a new “UnderCovered” series of exclusive articles featuring companies with limited coverage. Authors are compensated by TalkMarkets for their time, and otherwise represent their own assessments and opinions. Authors are not compensated by the subject companies in any way. This article is also part of our IR Insights Initiative in which articles about participating companies can receive greater visibility. To learn more click here.​ Contact Details TalkMarkets ir@talkmarkets.com

May 24, 2023 12:04 PM Eastern Daylight Time

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ImmuPharma "looking forward with quiet confidence" to FDA response

ImmuPharma PLC

Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

May 24, 2023 11:08 AM Eastern Daylight Time

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Voyager Life "now capable of dealing with multinational customers"

Voyager Life PLC

Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

May 24, 2023 11:03 AM Eastern Daylight Time

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Oxford Cannabinoid Technologies: Phase 1 approval for lead chronic pain drug

Oxford Cannabinoid Technologies Holdings PLC

Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

May 24, 2023 10:59 AM Eastern Daylight Time

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BioNTech's mRNA Vaccine Shows Early Potential Against Pancreatic Cancer

MarketJar

One of the most stubborn, deadly cancers is pancreatic cancer. What if individualized mRNA vaccinations could support the immune system's defense? One of the deadliest forms of cancer around, pancreatic cancer is estimated to kill 88% of patients. It’s also one of the most recurrent cancers, with roughly 90% of patients experiencing a relapse within seven to nine months after surgery. Fortunately, a recent study of an mRNA vaccine for pancreatic cancer patients has provided a glimpse of hope. Scientists at Memorial Sloan Kettering (MSK) Cancer Center in New York just published the results of a small study that the group conducted in partnership with Germany’s BioNTech on pancreatic cancer patients over several years. The study used a pancreatic cancer mRNA vaccine tailored to each patient’s tumor to potentially help provoke an immune response. What’s revolutionary about the vaccines is that the German scientists tailored them to the mutated proteins on the surface of cancer cells instead of a mix of tumor and normal cells, which has been the method tried for decades. The cells were extracted from patients’ tumors by researchers at Memorial Sloan and sent to BioNTech, the company that created the highly-effective COVID-19 vaccine alongside Pfizer. Among the participants in the study, half of the patients’ immune systems learned how to recognize and fight off the cancer cells and showed no signs of relapse during the 18 months they were tracked. While promising, personalized mRNA cancer vaccines are still in their infancy and are too costly to be broadly used. Right now, regular cancer screening remains the best method for detecting cancers, however there are currently no screening tests for pancreatic cancer. Fortunately, that could soon change thanks to Mainz Biomed (NASDAQ:MYNZ), a molecular genetics diagnostic company specializing in the early detection of cancer Developing Early Screening Tests for Colon and Pancreatic Cancers On May 10, Mainz Biomed announced a partnership with Microba Life Sciences for the creation of PancAlert in addition to early colon cancer diagnostics. The technical characteristics of a novel pancreatic cancer screening test with DNA and microbiota indications should be enhanced. As part of the agreement, the two companies will conduct a pilot research project utilizing Microba’s proprietary metagenomic sequencing technology and bioinformatic tools in an effort to discover novel microbiome biomarkers to detect pancreatic cancer. The project, which is expected to run until late 2023, will use Microba's Community Profiler (MCP), a proprietary metagenomic platform technology that has proven to be a best-in-class research tool that can produce comprehensive and accurate species profiles of gastrointestinal samples. Mainz Biomed (NASDAQ:MYNZ) is also focused on commercializing its flagship product ColoAlert, a highly efficacious and simple-to-use detection test for colorectal cancer (CRC) that is already available in select international territories. In Q1 2023, the company also launched a corporate health program in Germany by integrating into BGM, a well-established corporate health program that provides services to employees at 48 of the 50 largest companies in Germany. On May 24, Mainz Biomed announced initial results from its colorectal cancer screening campaign with Zöller-Kipper GmbH through its BGM partnership. In April 2023, Zöller-Kipper selected ColoAlert for its corporate health program, which includes over 2,500 employees. According to the results, employees found the online patient portal easy-to-use and convenient and were able to readily access the portal, request a kit and securely receive results within five days. In order to process the ColoAlert PCR test kit, Mainz Biomed has added Eurofins GeLaMed to its network of lab partners. Eurofins GeLaMed is a division of the global laboratory company Eurofins Scientific, which conducts 450 million tests annually and has over 61,000 employees in 61 nations. Germany is home to four of its locations. Advancing Towards FDA Approval to Bring ColoAlert to the US Market Over the last few months, Mainz Biomed has continued to prepare for patient enrollment in its pivotal clinical trial for ColoAlert after successfully completing its pre-submission process with the FDA. ColoAlert will be examined in the FDA-registered trial "ReconAAsense" in order to obtain commercial approval in the United States. The company's business objective is to create scalable distribution across the nation once it receives approval through a cooperative partner program with regional and national laboratory service providers. Learn more about Mainz Biomed (NASDAQ:MYNZ) and its activities by clicking on this link. Disclaimer 1) The author of the Article, or members of the author’s immediate household or family, do not own any securities of the companies set forth in this Article. The author determined which companies would be included in this article based on research and understanding of the sector. 2) The Article was issued on behalf of and sponsored by, Mainz Biomed NV. Market Jar Media Inc. has or expects to receive from Mainz Biomed NV’s Digital Marketing Agency of Record (Native Ads Inc.) eighty nine thousand seven hundred sixty four USD for 12 days (9 business days). 3) Statements and opinions expressed are the opinions of the author and not Market Jar Media Inc., its directors or officers. The author is wholly responsible for the validity of the statements. The author was not paid by Market Jar Media Inc. for this Article. Market Jar Media Inc. was not paid by the author to publish or syndicate this Article. Market Jar has not independently verified or otherwise investigated all such information. None of Market Jar or any of their respective affiliates, guarantee the accuracy or completeness of any such information. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security. Market Jar Media Inc. requires contributing authors to disclose any shareholdings in, or economic relationships with, companies that they write about. Market Jar Media Inc. relies upon the authors to accurately provide this information and Market Jar Media Inc. has no means of verifying its accuracy. 4) The Article does not constitute investment advice. All investments carry risk and each reader is encouraged to consult with his or her individual financial professional. Any action a reader takes as a result of the information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Market Jar Media Inc.'s terms of use and full legal disclaimer as set forth here. This Article is not a solicitation for investment. Market Jar Media Inc. does not render general or specific investment advice and the information on pressreach.com should not be considered a recommendation to buy or sell any security. Market Jar Media Inc. does not endorse or recommend the business, products, services or securities of any company mentioned on pressreach.com. 5) Market Jar Media Inc. and its respective directors, officers and employees hold no shares for any company mentioned in the Article. 6) This document contains forward-looking information and forward-looking statements, within the meaning of applicable Canadian securities legislation, (collectively, “forward-looking statements”), which reflect management's expectations regarding Mainz Biomed NV’s future growth, future business plans and opportunities, expected activities, and other statements about future events, results or performance. Wherever possible, words such as “predicts”, “projects”, “targets”, “plans”, “expects”, “does not expect”, “budget”, “scheduled”, “estimates”, “forecasts”, “anticipate” or “does not anticipate”, “believe”, “intend” and similar expressions or statements that certain actions, events or results “may”, “could”, “would”, “might” or “will” be taken, occur or be achieved, or the negative or grammatical variation thereof or other variations thereof, or comparable terminology have been used to identify forward-looking statements. These forward-looking statements include, among other things, statements relating to: (a) revenue generating potential with respect to Mainz Biomed NV’s industry; (b) market opportunity; (c) Mainz Biomed NV’s business plans and strategies; (d) services that Mainz Biomed NV intends to offer; (e) Mainz Biomed NV’s milestone projections and targets; (f) Mainz Biomed NV’s expectations regarding receipt of approval for regulatory applications; (g) Mainz Biomed NV’s intentions to expand into other jurisdictions including the timeline expectations relating to those expansion plans; and (h) Mainz Biomed NV’s expectations with regarding its ability to deliver shareholder value. Forward-looking statements are not a guarantee of future performance and are based upon a number of estimates and assumptions of management in light of management’s experience and perception of trends, current conditions and expected developments, as well as other factors that management believes to be relevant and reasonable in the circumstances, as of the date of this document including, without limitation, assumptions about: (a) the ability to raise any necessary additional capital on reasonable terms to execute Mainz Biomed NV’s business plan; (b) that general business and economic conditions will not change in a material adverse manner; (c) Mainz Biomed NV’s ability to procure equipment and operating supplies in sufficient quantities and on a timely basis; (d) Mainz Biomed NV’s ability to enter into contractual arrangements with additional Pharmacies; (e) the accuracy of budgeted costs and expenditures; (f) Mainz Biomed NV’s ability to attract and retain skilled personnel; (g) political and regulatory stability; (h) the receipt of governmental, regulatory and third-party approvals, licenses and permits on favorable terms; (i) changes in applicable legislation; (j) stability in financial and capital markets; and (k) expectations regarding the level of disruption to as a result of CV-19. Such forward-looking information involves a variety of known and unknown risks, uncertainties and other factors which may cause the actual plans, intentions, activities, results, performance or achievements of Mainz Biomed NV to be materially different from any future plans, intentions, activities, results, performance or achievements expressed or implied by such forward-looking statements. Such risks include, without limitation: (a) Mainz Biomed NV’s operations could be adversely affected by possible future government legislation, policies and controls or by changes in applicable laws and regulations; (b) public health crises such as CV-19 may adversely impact Mainz Biomed NV’s business; (c) the volatility of global capital markets; (d) political instability and changes to the regulations governing Mainz Biomed NV’s business operations (e) Mainz Biomed NV may be unable to implement its growth strategy; and (f) increased competition. Except as required by law, Mainz Biomed NV undertakes no obligation to update or revise any forward-looking statements, whether as a result of new information, future event or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. Neither does Mainz Biomed NV nor any of its representatives make any representation or warranty, express or implied, as to the accuracy, sufficiency or completeness of the information in this document. Neither Mainz Biomed NV nor any of its representatives shall have any liability whatsoever, under contract, tort, trust or otherwise, to you or any person resulting from the use of the information in this document by you or any of your representatives or for omissions from the information in this document. 7) Any graphs, tables or other information demonstrating the historical performance or current or historical attributes of Mainz Biomed NV or any other entity contained in this document are intended only to illustrate historical performance or current or historical attributes of Mainz Biomed NV or such entities and are not necessarily indicative of future performance of Mainz Biomed NV or such entities. Contact Details James Young +1 800-340-9767 campaigns@pressreach.com Company Website https://pressreach.com

May 24, 2023 09:00 AM Eastern Daylight Time

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Creo Medical Group "gaining a level of acceptance" in endoscopy

Creo Medical Group PLC

Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

May 23, 2023 11:15 AM Eastern Daylight Time

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Q-Vant Biosciences Announces Positive Study Results for Its Sustainable Quillaja-Based Vaccine Adjuvant, Q-VET-S®, in Kansas State’s Classic Swine Fever Vaccine

Q-Vant Biosciences

Q-Vant Biosciences, the first company to achieve a 100% sustainable way to meet the growing global vaccine market demand for Quillaja saponin-based adjuvants, today announced very positive results comparing Q-Vant's sustainable saponin-based adjuvant, Q-VET-S®, to Croda's Quil-A® adjuvant. These results were obtained through a collaborative study with Kansas State University, utilizing their subunit classic swine fever (CSF) vaccine. The CSF vaccine was developed by Kansas State professor Dr. Jishu Shi. Dr. Shi also serves as the director of the Center for Vaccine Evaluation, where he and his team are working on novel vaccine and diagnostic strategies aimed at better control and prevention measures targeting swine infectious diseases. This includes porcine reproductive and respiratory syndrome (PRRS), classical swine fever virus (CSF), African swine fever (ASF), and other emerging viral diseases of swine. Juan Jose Albarran, the chief commercial officer of Q-Vant Biosciences, said, "The development of Q-VET-S® and its proven effect marks a major milestone in the field of vaccine adjuvants. Our cutting-edge technology not only ensures a reliable supply for the pharmaceutical sector but also addresses the environmental concerns associated with Quillaja Saponaria harvesting. By focusing on sustainability, we are playing a significant role in protecting Chile's forests while simultaneously advancing global animal and human health." For more information about Q-Vant Biosciences and Q-VET-S, please visit www.q-vant.com. About Kansas State University: Kansas State University, established in 1863, is a leading public research university with a mission to foster excellent teaching, research, and service that develops a highly skilled and educated citizenry necessary to advancing the well-being of Kansas, the nation, and the international community. The university is committed to advancing knowledge through research and creative activities, developing leaders, and contributing to the global community's well-being. About Q-VANT Biosciences Q-VANT is a privately held biosciences company that has solved the supply chain problem of QS-21 and other Quillaja-based saponin adjuvants for the global human and animal pharmaceutical markets. The company’s next-generation technology platform combines computational learning techniques with a proprietary multi-step purification process to increase the supply of QS-21 by more than 1,000 – enabling the production of billions of doses annually to meet today’s increasing global market demand. Led by a team with unrivaled experience in vaccine and adjuvant development, manufacturing and global regulatory requirements, and with world-class knowledge in Quillaja saponin supply chain, agronomy, extraction and purification, Q-VANT is the first company that is vertically integrated to combine a secured sustainable Quillaja raw material supply with pharma cGMP commercial-scale production of QS-21 and other saponin-based adjuvants. For more information, visit www.q-vant.com. Contact Details Q-Vant Biosciences Doug Klaiber dklaiber@q-vant.com Company Website https://q-vant.com/

May 23, 2023 10:00 AM Eastern Daylight Time

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PathPresenter Surpasses 50,000 Global Users

PathPresenter

PathPresenter, the global image sharing platform for pathology, today announced that their free public platform ( https://pathpresenter.net/ ) now has more than 50,000 registered users in 172 countries. Nearly 7,000 users have joined the pathology image sharing community in the past 12 months. Founded by dermatopathologist and digital pathology innovator, Dr. Rajendra Singh, PathPresenter has become the go-to, on-line community for pathologists, residents, fellows, scientists, and researchers who want to easily upload, view, and share whole slide images with their colleagues, as well as access curated image datasets from trusted experts. With over 100,000 hours of real-world usage, users have embraced PathPresenter’s best-in-class, lag-free imaging performance, super-easy sharing of images with colleagues (through URL links and/or QR codes), and the platform’s pathologist-built functionality. The viral popularity of PathPresenter public has helped spur the adoption of PathPresenter’s robust and secure enterprise platform at tier-one institutions, becoming one of the fastest growing digital pathology enterprise workflow platforms for use in clinical care, education, and research. The “instant familiarity” of the PathPresenter platform and brand – used by pathologists at almost every major hospital in the world – translates into higher rates of adoption and user enthusiasm among pathologists and therefore a higher return on investment for institutions implementing new digital pathology enterprise workflows. “Within 5 years, the majority of the world’s 1 billion glass slides produced each year will be digital. PathPresenter is building the roads and bridges to enable petabytes (soon to be exabytes) of digital pathology images to flow easily and securely within and between institutions to advance patient care, research, and pathology education,” said Patrick Myles, Chief Executive Officer of PathPresenter. “I would like to thank our community of 50,000+ PathPresenter users around the world for their unwavering support and their continued valuable input into the platform.” “It is the feedback from great colleagues from around the world that has helped us build practical workflow solutions to use digital pathology in all three pillars of our work: clinical care of our patients by providing accurate diagnosis with prognostic information, educating new pathologists, and accelerating research for better care of patients,” added PathPresenter founder, Dr. Rajendra Singh. “We will continue to work tirelessly with colleagues, institutions, and other vendors to ensure we can truly revolutionize our field and make it the center of personalized medicine.” About PathPresenter PathPresenter is the global image sharing platform for pathology. We are on a mission to help democratize access to the world’s pathology knowledge by connecting pathologists to the vast expertise of their colleagues globally and providing a practical platform to access and use best-in-class AI models. Founded in 2017 by dermatopathologist and digital pathology innovator, Dr. Rajendra Singh, PathPresenter has been adopted by 30+ tier one medical institutions for clinical care, education, and research, and has built a thriving community of 50,000+ users in 172 countries to easily view and share digital pathology images and knowledge. Learn more about pathpresenter.com. PathPresenter is available for primary diagnosis in the US during the COVID-19 public health emergency. In other countries, PathPresenter is intended for research and educational purposes only. Contact Details PathPresenter Cory Batenchuk - SVP of Operations +1 873-355-9913 cory@pathpresenter.com About PathPresenter PathPresenter is the global image sharing platform for pathology. We are on a mission to help democratize access to the world's pathology knowledge by connecting pathologists to the vast expertise of their colleagues globally and providing a practical platform to access and use best-in-class AI models. Founded in 2017 by dermatopathologist and digital pathology innovator, Dr. Rajendra Singh, PathPresenter has been adopted by 30+ tier one medical institutions for clinical care, education, and research, and has built a thriving community of 50,000+ users in 172 countries to easily view and share digital pathology images and knowledge. Learn more about pathpresenter.com. Contact Details Cory Batenchuk +1 873-355-9913 cory@pathpresenter.com Company Website https://pathpresenter.com

May 23, 2023 10:00 AM Eastern Daylight Time

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Emergent Health and Apollo Biowellness Announce Strategic Collaboration

Emergent Health Corp.

Emergent Health Corp. (OTC: EMGE), a curator, developer, and marketer of products in the Regenerative Health Space announced today that it will be collaborating with Apollo Biowellness, Inc., the entity that Boustead has engaged to conduct an IPO of the roll up of the regenerative medicine space, previously announced by Emergent on May 18, 2023. Apollo is an aggregate of manufacturing, distribution and marketing of regenerative products and brands in the regenerative space. This partnership, along with the previously announced spin-off of PharmaZu will continue to build significant value to Emergent. As part of the roll-up being conducted by Boustead and Apollo Biowellness, effective June 1, 2023, Mr. Morrison will take over as President/CEO of Apollo Biowellness. Mr. Morrison will remain as a member of the Board of Directors of the Emergent and will assume the Title of Chairman of the Board. He will continue to be intimately involved with Emergent and the continued development, marketing and distribution of its products and brands, The two companies will coordinate marketing strategies, manufacturing and work together to expand the products and brands. Jim Morrison stated, “Since taking the helm of Emergent, I have enjoyed the process of creating the Company’s vibrant products and brands in the regenerative biologic space. The opportunity to coordinate between Emergent and Apollo and expand the value of these products and brands as President of Apollo Biowellness is an exciting opportunity and will bring expanded value to Emergent. I look forward to continuing to be involved in the dynamic offerings of Emergent going forward.” Jim Zimbler, a member of the Board of Directors, and previously the President of the Company, has been re-appointed as Interim President of the Company, also effective June 1, 2023. In addition to bringing on new senior management, the Company will be announcing a new CFO and a will conduct a new executive search for a new permanent full time CEO to work with the current management and Board and team and Mr. Morrison and the Apollo Biowellness team. The Company will announce more Management updates shortly. Jim Zimbler stated, “Jim Morrison has done a magnificent job during his tenure as President, and I know he will be a tremendous asset to Apollo Biowellness. I look forward to a close continued relationship with Mr. Morrison and leaning on him for his sizable experience and tutelage related to products and brands. That will greatly enhance the value Emergent will receive from the sale of Evolutionary Biologics and the other entities.” ABOUT EMERGENT HEALTH CORPORATION Emergent curates, develops and sells products in the Regenerative Health Space. Its products comprise of ingestibles as well as topicals for the whole family. The company distributes its products online and through Content Based Shopping using Influencers to position products in their produced content throughout the United States and Internationally. Its subsidiaries; PharmaZu, is a pure play, e-commerce products and service provider focused on the Pet Community, Pet Pharmacy and Pet Wellness using Influencers and their content, including the pet pharmacy, vet telehealth and pet wellness businesses. Evolutionary Biologics, is a new kind of biologics company founded for a clear purpose: bring cutting edge regenerative products to the medical community. Emergent does not claim any of its products are approved by the FDA to diagnose, treat, cure or prevent any disease. For more information, please visit Emergent's Website and Social Media on Twitter. Before using any products, you should always consult with your Veterinarian and/or Family Doctor. SAFE HARBOR STATEMENT This press release contains forward-looking statements that can be identified by terminology such as “believes,” “expects,” “potential,” “plans,” “suggests,” “may,” “should,” “could,” “intends,” or similar expressions. Many forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause actual results to be materially different from any future results implied by such statements. These factors include, but are not limited to, our ability to continue to enhance our products and systems to address industry changes, our ability to expand our customer base and retain existing customers, our ability to effectively compete in our market segment, the lack of public information on our company, our ability to raise sufficient capital to fund our business, operations, our ability to continue as a going concern, and a limited public market for our common stock, among other risks. Many factors are difficult to predict accurately and are generally beyond the company's control. Forward-looking statements speak only as to the date they are made, and we do not undertake to update forward-looking statements to reflect circumstances or events that occur after the date the forward-looking statements are made. FOR MORE INFORMATION, PLEASE CONTACT: Jim Morrison, Chairman of the Board James W. Zimbler – Interim President/Interim CEO Emergent Health Corporation Website i nfo@emergenthealthcompany.com Contact Details Emergent Health Corp. info@emergenthealthcompany.com Company Website https://emergenthealthcompany.com/

May 23, 2023 09:00 AM Eastern Daylight Time

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