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Context Therapeutics CTIM-76 bispecific antibody preclinical data presented at AACR Annual Meeting

Context Therapeutics

Context Therapeutics CEO Marty Lehr joins Proactive's Natalie Stoberman to discuss CTIM-76 preclinical data presented at the American Association for Cancer Research (AACR) Annual Meeting 2023. Lehr noted the latest CTIM-76 bispecific antibody data and developments were shared with investors and colleagues as Context prepares for an Investigational New Drug application filing in early 2024. CTIM-76 is a Claudin 6 (CLDN6) X CD3 bispecific antibody currently in preclinical development that is capable of binding to tumor cells expressing CLDN6 and stimulating intra-tumoral T cells by the CD3 arm that is designed to be activated only upon tumor engagement while silent elsewhere. CLDN6 is expressed in multiple solid tumors, including ovarian, lung, and testicular cancers. The R&D webinar presentation can be found here: https://ir.contexttherapeutics.com/static-files/9377e4ba-bce3-4daa-a4f5-708b6a7c61dc Contact Details Proactive Investors USA +1 347-449-0879 na-editorial@proactiveinvestors.com

April 24, 2023 12:01 PM Eastern Daylight Time

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Tonix Pharmaceuticals TNX-1500 monoclonal antibody published in American Journal of Transplantation

Tonix Pharmaceuticals

Tonix Pharmaceuticals CEO Seth Lederman joins Proactive's Natalie Stoberman to share the findings of two publications in the American Journal of Transplantation that demonstrate how the company's TNX-1500 monoclonal antibody product candidate aided in the prevention of organ rejection for kidney and heart transplants. Lederman says these animal studies found that TNX-1500 retains activity to prevent rejection and preserve graft function. He adds that Tonix expects to start a first-in-human Phase 1 study in the second quarter of 2023 of TNX-1500 for prophylaxis of organ rejection in adult patients receiving a kidney transplant. Contact Details Proactive Studio +1 347-449-0879 na-editorial@proactiveinvestors.com

April 24, 2023 11:34 AM Eastern Daylight Time

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American Diversified Holdings Corporation Enters CBD Market with Leading Partners

American Diversified Holdings Corp.

McapMediaWire -- American Diversified Holdings Corporation (OTC: ADHC) is pleased to announce today that the company, through its brands UNIVERSAL WELLNESS and Amazon vendor RollsChoice™, has reached a comprehensive alliance with GGII's leading group of companies in the CBD and Hemp sector. ADHC's agreement with Green Globe International Group (OTC: " GGII "), Hempacco (NASDAQ: " HPCO ") and GGII's operating subsidiary Green Star Labs provides for a broad range of services and interrelated business activity. The synergies of this alliance are derived from the cross-branding of the products. The GGII/HEMPACCO/GREENSTAR group has entered into this alliance with ADHC and will collaborate as outlined below: Formulation, manufacturing, private label, inventory management, packaging and shipment logistics with be provided by Green Star Labs under the Universal Wellness and RollsChoice™ Jointly design a line of CDB, Dietary Supplements and Cosmetic products to be offered through ADHC' e-commerce platform www.UniversalWellnessShop.com Introduce and negotiate endorsement agreements with social media influencers and noted HipHop/Rap luminaries. Hempacco currently has relationships deals with Snoop Dogg Brands, rap artist Rick Ross, Hemp Hop Smokables and Cheech and Chong, Hemp Cigarettes. Parties have agreed to a financial partnership including share issuances, line of credit for product inventory, capital formation, and addition of future management. Parties have agreed to assess the development of ADHC existing brand and future products under development, including products sold under the of cannabis adhesive pens and lifestyle and CBD products. This alliance is set to springboard ADHC'S branded products into the rapidly growing CDB market sector. A recent report by Market Research Future (MRFR) indicated the CDB market is expected to reach over $59 billion by 2030 an 18% CAGR. This alliance is set to springboard ADHC'S branded products into the rapidly growing CDB market sector. A recent report by Market Research Future (MRFR) indicated the CDB market is expected to reach over $59 billion by 2030 an18% CAGR. See: Cannabidiol (CBD) Market Size Worth USD 59.3 Billion by (globenewswire.com) "This alliance with ADHC's Universal Wellness and RollsChoice ™ brands is a great opportunity for us to build revenues with a valued partner", commented Sandro Piancone, CEO of GGII and HPCO, "We look forward to hitting the ground running for a long term mutually beneficial alliance that enables us to sell products that have the attributes and features that represent the best parts of each brand." "The GGII/HPCO team is truly brilliant alliance partner for ADHC, we can now focus on pushing our brands to the forefront of the CBD and Cannabis markets with a manufacturing and brand building partner that is a dream come true for our shareholder", commented ADHC management. About Hempacco (NASDAQ: HPCO ) Hempacco Co., Inc.'s goal is Disrupting Tobacco's™ nearly $1 trillion industry with herb and hemp-based alternatives to nicotine cigarettes by manufacturing and marketing herb, spice, and cannabinoid smokables and rolling paper. Hempacco owns The Real Stuff™ functional hemp cigarette and rolling paper brand. Hempacco's operating segments include: Manufacturing of smokables, hemp rolling paper, and cannabinoid sticks Smokable technology development The Real Stuff™ brand of functional smokables and rolling paper Cheech and Chong Hemp Cigarettes and Hemp Hop Smokables with Rick Ross Snoop Dogg Joint Venture of Hemp-Derived Products Learn more at www.hempacco.com. Order products at www.realstuffsmokables.com. About HempBox Vending HempBox Vending offers a kiosk solution for smart vending technology to sell quickly moving consumer goods, including but not limited to nutraceuticals, CBD, hemp, herb, and spice smokables. About Green Globe International, Inc. (OTC: GGII ): Green Globe International is a Fast-Moving Consumer Goods incubator and holding company of intellectual property, products, and companies that better people's lives by helping them feel and look better inside and out. Green Globe International ( GGII ) owns or has interests in several brands and companies including; Green Star Labs, Inc., changing how people feel about themselves inside and out with nutritional supplements, CBD, and beauty products, and hemp CBD cigarette and rolling paper manufacturer Hempacco Co. Inc., (NASDAQ: HPCO ) Disrupting Tobacco's™ $1 Trillion tobacco industry, with its subsidiaries and joint ventures including HempBox Vending, Inc. a vending and advertising company, Hempacco Paper Company, Inc., producing The Real Stuff Hemp Smokables and hemp paper smoking products like blunts, tubes, and cones, Cali Vibes, Inc. manufacturing cannabinoid cigarettes, HempHop Smokables, Inc., partnering with music producer and rapper Rick Ross, Cheech and Chong Smokables, Inc. delivering cannabinoid Hemp CBD cigarettes to consumers with Cheech and Chong as partners, StickIt USA, Inc., manufacturing a line of cannabinoid sticks, and HPDG, LLC a partnership with Snoop Dogg to develop hemp-derived consumer goods products. Green Globe International is publicly traded under the ticker symbol (OTC: GGII ). It continues to look for best-in-class companies, products, and patents to create Fast Moving Consumer Goods and channels to sell them, including retail automation and advertising platforms. ABOUT ADHC/UNIVERSAL WELLNESS/ROLLS CHOICE: ADHC is a publicly traded holding company trading under the ticker symbol (OTC: ADHC ). ADHC is currently developing two web-based branded businesses. Universal Wellness (UWS) is a wellness and lifestyle e-commerce site focused on providing innovative products, news, and the latest healthcare developments RollsChoice™ is a Southern California-based manufacturer, distributor, and e-commerce company selling an all-natural Adhesive Glue and application device sold off AMAZON.com and through its own website. The Pens come in 1 ml, 2 ml, and 100 pen packs. RollsChoice™ has significant brand awareness in the cannabis industry and boasts over 80,000 followers on Twitter and Instagram. Recently over 12,000 adhesive pens have been manufactured and sold. The adhesive is made of Food Grade Premium ingredients. RollsChoice™ Adhesive Pen is Flavorless, Colorless, Tasteless and Stainless. It is used to seal cannabis and tobacco rolled products including blunts, joints, cigars and hand rolled cigarettes in a sterile manner allowing for long lasting adhesive qualities. The proprietary brush tip pen is recommended for precision. RC sells direct to smoke shops, dispensaries and direct to consumers through its e-commerce site. Through the companies multi year history sales over 12,000 adhesive pens and been manufactured and sold by RollsChoice™. see (USPTO ROLLS CHOICE 97278083). RollsChoice™ has over 80,000 social media followers which will be introduced to ADHC social media platforms on Twitter, Instagram, Facebook, and TikTok. This relationship will establish a very strong presence providing brand awareness to potential customers and shareholders as the Universal Wellness/Rolls Choice business relationship develops and revenues grow. Website: www.Rollsschoiceadhesive.com Email: rollschoicerepresentative619@gmail.com Twitter: https://www.twitter.com/rollschoice Instagram: https://www.instagram/rollschoicadhesivepen In addition to the adhesive pen, RC has numerous other cannabis related products being developed that will be introduced as a result of this Acquisition agreement. Shareholders, customers, and other interested parties can find product offerings by searching AMAZON under these UPC codes: B0B1BTNW4Q and B0B2R3D2TS or clicking this link: https://a.co/d/3ONJjG Amazon.com: Rolls Choice™ Adhesive Pen (25, 1ml) RollsChoice™ has a pending trademark with the USPTO under application number 972978083. LITIGATION UPDATE ADHC has filed suit in The Eight Judicial Circuit Court, Clark County, Nevada case Number A-21-843-670, seeking the cancellation of 330,000,000 (330 MM) shares of common stock. On January 6, 2023, the court granted the motion for default. It is anticipated that the court will be issuing the formal order soon on a scheduled hearing date of April 17th, 2023. Granting the default judgment is the final legal step before all litigation is resolved. Currently, ADHC capitalization structure is as follows: Shares Outstanding: 1.1 billion Shares Restricted: 600 million Shares in the Float: 504 million Investor Contact: Ernest Remo Chairman/CEO EMAIL: ernestremo@san.rr.com Tel: 858-259-4534 TWITTER: @ADHCManagement. This Twitter page is the only official Twitter page for ADHC. Information contained herein includes forward-looking statements. These statements relate to future events or future financial performance, involving known and unknown risks and uncertainties that may cause our actual results to be materially different from the performance or achievements expressed. You should not place undue reliance on these statements since they involve known and unknown risks, in some cases, beyond our control. SAFE HARBOR These statements relate to future events or future financial performance, involving known and unknown risks and uncertainties that may cause our actual results to be materially different to performance or achievements expressed. You should not place undue reliance on these statements, since they involve known and unknown risks. Any forward-looking statements reflect the current view with respect to future events and subject to uncertainties Contact Details Ernest Remo ernestremo@san.rr.com Company Website http://www.universalwellnessshop.com/

April 24, 2023 06:00 AM Eastern Daylight Time

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Arecor Therapeutics has "a strong basis to accelerate" growth strategy

Arecor Therapeutics PLC

Arecor Therapeutics PLC (AIM:AREC) CEO Sarah Howell speaks to Thomas Warner from Proactive after releasing preliminary full-year results for 2022. She gives her take on the highlights from last year before going on to lay out what investors can expect from the business during 2023. Howell says that Arecor has a "strong basis to accelerate" its growth strategy and "plenty to look forward to." Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

April 24, 2023 03:00 AM Eastern Daylight Time

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Faron Pharmaceuticals "confirms promising results from first cohort"

Faron Pharmaceuticals Oy

Faron Pharmaceuticals Chief Medical Officer Marie-Louise Fjällskog speaks to Proactive about progress on the clinical stage biopharmaceutical company's BEXMAB study. Fjällskog "confirms promising results from the first cohort" and highlights plans to go to the FDA "very soon" to share the company's plan for "getting into an accelerated approval pathway". Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

April 24, 2023 03:00 AM Eastern Daylight Time

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Kromek Group announces two "key contract" wins

Kromek Group PLC

Kromek Group PLC (AIM:KMK) CEO Arnab Basu speaks to Thomas Warner from Proactive following a week of announcements that include two "key contract" wins and a Q3 trading update. Basu said the contracts validate the growth story at Kromek, which had been working for several years to build relationships with OEMs. In its Q3 trading update, Kromek recorded a 50% YoY growth in revenues. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

April 24, 2023 03:00 AM Eastern Daylight Time

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RespireRx collaborates with University College London to study treatment options for GRIA disorders

RespireRx Pharmaceuticals

RespireRx Pharmaceuticals chief scientific officer Arnold Lippa joins Proactive's Natalie Stoberman to share details of the company's latest collaboration with University College London to study the use of AMPAkines for the treatment of GRIA disorders. GRIA Disorder refers to a family of rare genetic diseases caused by mutations in the AMPA glutamate receptor genes that cause either a loss or gain in the functioning of these receptors, which are the site of action of RespireRx’s AMPAkines and which play an important role in learning and memory as well as other critical biological functions. Contact Details Proactive Investors +1 347-449-0879 na-editorial@proactiveinvestors.com

April 21, 2023 10:52 AM Eastern Daylight Time

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Tiziana Life Sciences plans to file Investigational New Drug Application for Alzheimer's treatment

Tiziana Life Sciences PLC

Tiziana Life Sciences chief medical officer Dr Matthew Davis joins Proactive's Natalie Stoberman to share how the company is planning to file an Investigational New Drug (IND) application for intranasal foralumab as a treatment of Alzheimer's disease. Dr Davis says there are no FDA-approved treatments for Alzheimer’s disease specific to neuroinflammation. He adds that the goal is to study three months' administration of intranasal foralumab in Alzheimer’s disease patients to see if neuroinflammatory-activated microglia will return to the baseline homeostatic state. The IND also includes seeking $3 million in non-dilutive funding from a prestigious Alzheimer’s foundation to support the Phase 2a trial. Contact Details Proactive Investors +1 604-688-8158 na-editorial@proactiveinvestors.com

April 21, 2023 10:47 AM Eastern Daylight Time

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NeuroRestorative Kentucky Celebrates 20th Anniversary of Paducah Location

Sevita

NeuroRestorative is celebrating the 20 th anniversary of its NeuroRestorative Paducah program. Paducah is one of four NeuroRestorative program locations in Kentucky while the NeuroRestorative footprint at large spans 28 states. An open house was held on Tuesday, April 18, with Kentucky state delegates, local leaders and community members, program staff, individuals served and their loved ones. The event honored program participants, sharing their stories and celebrating their successes and hard work. In 2002, the Paducah program became the first brain injury program in Kentucky. What began as a 3-room standalone service provider for people with brain injuries has since grown both in size and in the quality of care provided. With increased clinical and patient care, resources, community support, and physical expansion, NeuroRestorative Paducah has evolved over the past two decades into a nationally-recognized center of excellence in treating post-acute neurological trauma. “NeuroRestorative provides vital services to those in need of help with Traumatic Brain injuries,” says State Representative Steven Rudy, who gave remarks at the event. “I support the mission of this program and strongly believe Kentucky is fortunate to provide these services.” NeuroRestorative Kentucky provides a wide range of active rehabilitation and other supports for people of all ages with brain injury and other neurological challenges in both residential and outpatient settings. Services include neurorehabilitation and physical, occupational and speech therapy, as well as community integration and life skills training, and more. NeuroRestorative Paducah currently serves 53 individuals, including those with short and long-term care needs. The program is supported by 108 staff members including healthcare professionals (physical therapists, occupational therapists, nurses etc.), social workers, and residential supervisors. “We are so proud to celebrate our 20 th year supporting the people of Western Kentucky,” said Jane Stahl, Executive Director of NeuroRestorative Kentucky. “We have built a community here in Paducah and every individual who walks through our doors joins the NeuroRestorative family.” Stahl continued, “We have program individuals that have been with us for 10+ years and team members who have been with us for nearly 20! We are invested in the wellbeing of the individuals in our care and cherish every opportunity we have to hear them speak about their journeys and the work they have put in to achieve their goals. They are here, doing incredible work and living a life of value and purpose.” Approach: As a leading, national provider of rehabilitative services, NeuroRestorative leverages their expertise and resources as an organization on the cutting-edge of clinical care. The exceptional team at NeuroRestorative programs demonstrate clinical proficiency and utilize a time-tested approach that has a proven track record of delivering successful outcomes for individuals along each stage of the continuum of care. The Paducah program is accredited by The Commission on Accreditation of Rehabilitation Facilities (CARF). NeuroRestorative participants work toward overall increase in function and level of independence from the time of admission to the time of discharge, as measured by standardized assessments like the Mayo-Portland Adaptability Inventory version 4 (MPAI-4). Success: One individual who has seen such success with NeuroRestorative Paducah, and spoke about his story at the open house, is Kerry Frazier. In October of 2019, Kerry (67), while working construction, fell from a chimney landing on his head and neck. He suffered multiple broken bones including three skull fractures, a broken back, collarbone, scapula, ribs, a punctured lung, and multiple cracked vertebrae. After being rushed to the hospital, his sisters recall the doctors noting they did not expect him to survive the first few weeks. Kerry, now, nearly four years after his accident, has proved them all wrong. Starting in 2020, Kerry received residential support at NeuroRestorative Paducah. Thanks to his hard work in physical and speech therapy, Kerry is back living at home and has gotten back to nearly everything he was able to do before his accident. He spends his days gardening, taking care of his home, and living a full, independent life. Learn more: Visit the NeuroRestorative site to read more successful outcomes stories, and find more information on the NeuroRestorative programs throughout Kentucky. ### About NeuroRestorative NeuroRestorative is a leading provider of subacute and post-acute rehabilitation services for people of all ages with brain and spinal cord injuries and other neurological challenges. In various locations and settings, we offer a continuum of care and community-based programs, including specialized services for children and adolescents, adults, military service members and veterans, injured workers, and the elderly. Our dedicated team of professionals is focused on empowering individuals to achieve their potential through a continuum of outcome-driven, community-based rehabilitation programs and specialized supports. Contact Details Melissa Patricio media@sevitahealth.com Company Website https://neurorestorative.com/

April 21, 2023 10:00 AM Eastern Daylight Time

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