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How Carbyne Closed an Oversubscribed Series C in the Middle of Financial Market Turmoil

Carbyne

This is a challenging year for tech companies, especially for entrepreneurs seeking funding for their next phase of growth. According to Pitchbook, VC funding was down 8% in the first six months of the year, driven by the sliding shares of mature tech companies. The NASDAQ composite index is down close to 25% through September. And yet, despite the liquidity crunch, Carbyne secured $56 million to invigorate the public safety industry with modern cloud-native technology. While I’ve raised capital at Carbyne and previously managed companies through the IPO process, this cycle was remarkably different. For Carbyne, this round will help us accelerate our global expansion and help us achieve our target of covering one billion people by 2024. Here are some important lessons I learned while closing this round in today’s treacherous fundraising environment. Expect a Roller Coaster Ride As we entered 2022, the financial markets were riding at all-time highs, and investors were looking to deploy their surplus cash in high-return opportunities like those offered by startups. Within a matter of weeks, the markets cratered, and pessimism spread rapidly across the financial markets. Unable to fulfill their own financial commitments, fund managers were looking to rationalize their positions, and the flight to safety was in full swing. We started the round right when the financial markets started to tumble, not expecting it would last throughout the year. A couple of times, the deal was on the cusp of closing and then, at the last moment, there was a surprise turn in the process. Investors’ sentiment changed almost overnight due to the macro environment, and we went back to square one. The key to riding the roller coaster of the fundraising process is to stay focused on investor feedback and to expect the unexpected. Be Flexible, Adapt Quickly to Changes, and Focus on the Right Investors Companies like Carbyne that successfully navigated the volatile markets of early 2022 got a few critical things right. For one, we realized that the tide was turning, and we adapted to the changes quickly. We adjusted our ask to investors, whose portfolios were reeling from the downturn. While we focused on the bull market case, we developed a base case and also bear case scenarios. Scenario modeling is key in a challenging market like this one – it’s crucial to show financial models that span from bull to bear case. We also continued engaging with more investors in our pipeline, targeting potential partners whose investing mandates would align with our mission and who would believe in our vision and guide us toward our North Star. Companies in fundraising mode should focus on finding investors who understand their business and are excited to join in their journey. Value choosing the right partner, even if they are not the highest bidder. Build Plan B and C Startups should always keep an ear to the ground and wake up earlier to shifting investor sentiment. Build lots of wiggle room into the process and prepare for unexpected delays within the plan. Right now, having just a plan A is not sufficient. Companies need to build plan B and plan C. Build these plans for base and bear cases without changing your vision and mission. We started the process a lot earlier and kept plans A, B, and C ready to execute. As they say, plan for the worst and prepare for the best. Be Open to Different Structures for the Round In cash-constrained environments, when it becomes difficult to raise equity, startups should calculate the cost of equity and the cost of debt. Be open to adjusting the size of the round, show investors your flexibility in the round size, and most importantly, build flexibility into your financial models. Don’t be afraid to explore alternative ways to raise capital, such as debt. We should dispel the stigma associated with raising debt financing since it can bring unique advantages. The cost of debt is usually lower than equity in the long run if you are confident in hitting your financial targets and forecasts. Furthermore, debt financing has the added benefit of not diluting existing investments. The environment today is much different than it was only a year ago. The key to successfully reaching your funding goals is to be agile and flexible while staying true to your mission. About Carbyne Carbyne (Headquartered in New York, NY) is a leading global provider of cloud-native mission-critical contact center solutions. Carbyne is one of the largest rich-data providers for emergency response centers, delivering over 250M data points per year all in a unified platform. Our technologies enable emergency contact centers and select enterprises to connect with callers as well as connected devices via highly secure communication channels without needing to download a consumer app. With a mission to redefine emergency collaboration and connect the dots between people, enterprises, and governments, Carbyne provides a unified cloud-native solution that provides live actionable data that can lead to more efficient and transparent operations and ultimately save lives. With Carbyne, every person counts. Contact Details For media inquiries please contact: Kerens@carbyne.com Company Website https://carbyne.com/

October 07, 2022 09:00 AM Eastern Daylight Time

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REPRISE BIOMEDICAL ANNOUNCES U.S. LAUNCH OF MIRO3D® THREE DIMENSIONAL RESORBABLE WOUND MATRIX

Reprise Biomedical

Reprise Biomedical, Inc., an innovative medical device company focused on developing and commercializing biologic solutions using its proprietary perfusion decellularization technology, has commenced U.S. sales of its Miro3D wound matrix through its direct U.S. sales force and independent sales agent network. Reprise received FDA 510(k) clearance for Miro3D on August 18, 2022, and initial clinical evaluations have already been successfully completed. Miro3D is a three-dimensional (2cm thick) biological matrix designed to be cut and shaped to fill deep or tunneling wound beds. Manufactured from decellularized porcine liver, Miro3D is a highly porous matrix which allows rapid cellular infiltration and integration in situ. Miro3D is the first U.S. commercially available wound matrix that is designed to fill a wound with its three-dimensional scaffold, rather than cover the wound with a traditional two-dimensional wound dressing. Dr. Moses Shieh of Lee Memorial Hospital and Surgical Healing Arts in Fort Myers, FL commented on his first clinical uses of Miro3D: “Miro3D has the potential to be a substantial advance in my wound care practice. My first cases included a stage IV sacral pressure ulcer which had been present for greater than 13 months and a post panniculectomy surgical dehiscence wound which had a 4cm medial undermining region, with both patients now progressing nicely toward full healing. Miro3D has volume and depth like no other product available in our health system. With these early clinical results, I am encouraged that Miro3D has the potential to drastically reduce length of stay in the hospital for patients with these complex wounds.” Dr. Brian Parkes of Scotland Memorial Hospital in Laurinburg, NC commented on his first clinical use of Miro3D: “I was eagerly awaiting FDA clearance of Miro3D since it provides a three-dimensional approach that was previously unavailable. My first Miro3D surgery was a necrotizing fasciitis patient who had a previously placed two-dimensional matrix but was experiencing delayed healing. Miro3D was easy to handle, robust to suture in place, and at follow-up, the results were remarkable. The wound responded with great granulation within just five days, and was ready for skin grafting, something that I would never have expected in this type of patient.” Carrie Powers, CEO of Reprise Biomedical, added the following: “We are excited to advance the treatment of deep and tunneling wounds, a U.S. market opportunity we estimate at over $1.4 billion annually, with our launch of the transformative Miro3D wound matrix. Because the most difficult to treat wounds are three-dimensional, advanced wound care surgeons have been asking for a product that can fill the wound, rather than just cover it. Our launch of Miro3D is Reprise’s first step in offering a range of three-dimension matrices with unique delivery systems designed to treat deep wounds and improve patient lives by quickening their recovery." About Miro3D Miro3D is available in four sizes (2x2cm, 3x3cm, 5x5cm and 5x10cm), with all sizes having a thickness of 2cm. Miro3D is also available in a Fibers configuration, consisting of a tray of loose fibrillar strands designed for packing small crevices and tunnels in wound beds. Photographs of Miro3D and before and after photographs of initial clinical uses are available on Reprise’s website at reprisebio.com/Miro3D. Miro3D wound matrix is intended for the management of wounds including: partial and full thickness wounds; pressure ulcers; venous ulcers; chronic vascular ulcers; diabetic ulcers; tunneled, undermined wounds; trauma wounds (abrasions, lacerations, second-degree burns, and skin tears); draining wounds; and surgical wounds (donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric, wound dehiscence). About Reprise Biomedical Reprise Biomedical’s mission is to deliver solutions to the unmet clinical needs of physicians in biological medical device markets. To learn more about Reprise Biomedical and its medical devices, visit reprisebio.com. ### Contact Details Reprise Biomedical, Inc. Carrie L Powers +1 763-284-6780 cpowers@reprisebio.com Company Website https://reprisebio.com

October 06, 2022 04:00 PM Central Daylight Time

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World Mental Health Day Press Conference with National Experts on Mental Health

Shatterproof

On World Mental Health Day (Monday, October 10), more than 180 leaders from across the country are gathering to launch a national movement to end the stigma around mental health and substance use disorders. World Mental Health Day kicks off the two-day Summit where organizations representing different industries and sectors, including federal and NGOs, will unite their drive and expertise to create powerful strategic actions to end the shame and prejudice caused by stigma. Media is invited to attend the press conference in person or virtually via Zoom. Leaders will speak for 2-3 minutes followed by Q&A. One-on-one interviews will be available following the Q&A. Who: National leaders on mental health and substance use disorders including: ● Kristin Kroeger, Chief of Programs, Policy, & Partnerships, American Psychiatric Association ● Jared Skillings, Chief of Professional Practice, American Psychological Association ● John MacPhee, Chief Executive Officer, The Jed Foundation ● Gary Mendell, Founder and CEO, Shatterproof ● Eve Byrd, Director of Mental Health Programs, Carter Center ● Janet Lindow, PhD, Executive Director & Co-Founder, Rural Behavioral Health Institute Complete list of national organizations attending the Summit When: Monday, October 10. Media preset time is 12:25 p.m. Press conference will begin promptly at 12:30 p.m. (MST) Where: Cliff Lodge, Snowbird Resort (Entry 4), Primrose B (Floor L) 9320 Cliff Lodge Dr, Snowbird, UT 84092 Or Virtual via Zoom Meeting ID: 925 7820 1741 Password: summit Why: 1 in 5 U.S. adults experience mental illness each year and substance use disorder affects more than 20 million Americans aged 12 and over. Moreover, 9.5 million adults over 18 have both a substance abuse disorder and a mental illness. While the numbers of people experiencing mental health and substance use disorders are staggering, stigma often prevents individuals and many communities from seeking the help they need. Visuals: Press conference and a collaborative session on road mapping the path to end the stigma around mental health and substance use disorders. About Shatterproof: Shatterproof is a national nonprofit organization dedicated to reversing the addiction crisis in the U.S. Shatterproof harnesses the models of business, the rigor of science and the power of a national movement to create change and save lives through three pillars of work: revolutionizing the addiction treatment system, breaking down addiction-related stigmas and supporting and empowering our communities. Find Shatterproof on Facebook, Twitter and YouTube: @ShatterproofHQ or follow them on Instagram at @weareshatterproof. To learn more, visit www.Shatterproof.org. Contact Details Shatterproof Lauren Lawson-Zilai +1 240-910-5483 press@shatterproof.org Huntsman Mental Health Institute Jerilyn Stowe +1 801-243-5764 jerilyn.stowe@hsc.utah.edu R&R Partners Kelsey Richardson +1 801-913-9454 kelsey.richardson@rrpartners.com Company Website https://www.shatterproof.org/

October 06, 2022 03:20 PM Eastern Daylight Time

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AmeriLife Partners with Senior Services of Illinois

AmeriLife

AmeriLife Group, LLC (“AmeriLife”), a national leader in developing, marketing, and distributing life and health insurance, annuities and retirement planning solutions, announced today that it has partnered with Senior Services of Illinois, Inc. Alongside its sister company Consumers Direct Insurance Services, Inc. as well as licensed insurance agency ToInsure.me, Senior Services of Illinois is a market leader in delivering quality insurance services and customer advocacy to Medicare beneficiaries and retirees across the midwestern and western United States. Per the agreement, terms of the deal were not disclosed. "We’re excited to join forces with AmeriLife and add our name to an incredible roster of brands and businesses,” said Scott Loochtan, founder and president of Senior Services of Illinois. “Most importantly, Senior Services of Illinois’s same customer-first approach will continue. The future is bright, and we look forward to growing together." Headquartered in Riverwoods, Ill., and founded in 1997 by Loochtan out of his father’s candy factory, Senior Services of Illinois has grown to serve more than 30,000 clients across five states, including New Mexico, Oklahoma, Colorado and Texas. As an independent, authorized exclusive general agent for Blue Cross and Blue Shield of Illinois, the company prides itself on offering its clients both exemplary service and quality insurance services. Despite its tremendous growth over the years, Senior Services of Illinois has remained true to its family roots, and its team of dedicated education specialists and customer advocates are a testament to the company’s people-first approach that has allowed it – and its clients – to thrive. “Senior Services of Illinois has proven to not only be an incredibly performative company, but one whose culture and values aligns perfectly with ours,” said Mike Vietri, AmeriLife’s Chief Distribution Officer. “We couldn’t be happier to welcome Scott and his team to the AmeriLife family, and look forward to accelerating their growth with the industry-leading resources, technology and expertise that’s become the hallmark of AmeriLife’s growing Distribution.” ### About Senior Services of Illinois Senior Services of Illinois, Inc. (SSI), alongside its sister company, Consumers Direct Insurance Services, Inc. (CDIS) and licensed insurance agency ToInsure.me, is an independent, authorized exclusive general agent for Blue Cross and Blue Shield of Illinois. A family-run business based in Riverwoods, Ill., with offices in New Mexico, Oklahoma and Texas, SSI prides itself on providing clients with exemplary service and quality insurance solutions. For more information, visit SSIInsure.com. About AmeriLife AmeriLife’s strength is its mission: to provide insurance and retirement solutions to help people live longer, healthier lives. In doing so, AmeriLife has become recognized as the leader in developing, marketing, and distributing life and health insurance, annuities and retirement planning solutions to enhance the lives of pre-retirees and retirees across the United States. For more than 50 years, AmeriLife has partnered with top insurance carriers to provide value and quality to customers served through a distribution network of over 300,000 insurance agents and advisors and more than 100 marketing organizations and insurance agency locations nationwide. For more information, visit AmeriLife.com, and follow AmeriLife on Facebook and LinkedIn. Contact Details Media Jeff Maldonado +1 321-297-1112 jmaldonado@amerilife.com Partnership Inquiries Patrick Nichols +1 727-726-0726 pnichols@amerilife.com Company Website https://amerilife.com/

October 06, 2022 02:00 PM Eastern Daylight Time

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15 Best Essay Writing Services Available Online

Writing Solutions

Essay writing can be complicated. It will often require hours spent in front of a computer or the library researching every possible part of your topic. This is not only a time-consuming process but oftentimes exhausting one that does not yield the results one might have hoped for. If you are tired of all of your hard work going unrewarded, or if you are simply running late and require help with completing an essay last minute, then the best thing you can do is actually hire a good quality essay writing service. The best essay writing services, which will be presented below, will offer you many different options in terms of which writers you can choose from, how quickly they can deliver your work, the quality of each essay, and the pricing available. By choosing one of the TOP 15 writing services presented below you are guaranteed to be able to receive a great mark on all of your essays without having to suffer through the stress of completing all of the work below. 99Papers - the best essay service overall [Rating 9.9] PaperHelp - winner from TOP writing companies in the USA [Rating 9.8] EssayBox - professional college paper writing provider [Rating 9.6] EssayPro - cheapest essay writers [Rating 9.5] Studdit - newest company to purchase an essay online [Rating 9.4] SpeedyPaper - fastest paper writing website [Rating 9.3] EssayFactory - recommended for students from the UK [Rating 9.1] 1Essay - the best admission essay writing service [Rating 9.0] IQEssays - the best customer support [Rating 8.9] PaperCoach - good discounts up to 15% [Rating 8.7] Ivory Research - TOP-rated company from the United Kingdom [Rating 8.6] WiseEssays - essay writing website with free features [Rating 8.4] SuperbPaper - high quality no-plagiarized papers [Rating 8.3] HomeWorkforMe - the best homework help company [Rating 8.1] MyAdmissionEssay - application essay writing provider [Rating 8.0] The best essay writing services will be assessed in several ways below. These will include pricing, the ease of use and way the that they work, overall reviews and feedback as well as all of their pros and cons. By looking at all of these different aspects you will be able to make an educated decision on which writing service will serve you best. TOP 15 Best Essay Writing Services Reviews #1. 99Papers 99Papers is one of the most popular writing services and for good reason. This option is extremely affordable but still offers a high quality of essays. All of their essays are top-rated, and they have employees available to work on your essays 24/7. To put it simply, with their service you can get your essay back fast and you will manage to get a great result on it. How does it work? Perhaps one of the easiest writing services one can use, with 99Papers you are immediately taken to a page that provides you with a price estimate based on the following categories: Essay Type – this can include academic essays, personal statements, admission essays, term papers, and many more; Academic Level – Everything from High School to Ph.D. level included; Deadline for Paper – This can range from as little as 3 hours to more than 15 days; Length – Pages and Words. Based on the choices you make in those sections you will get a price estimate. You can also make the following options which can affect the price you are paying. Writer level: Standard, top writer, and native writer are available; Additional services: Plagiarism reports, copy of sources, summary and priority support. Finally, you can apply any discount codes you might have to bring down the price. Then you will need to proceed to your paper details. This is where you will get to include all of the specifics of your paper before placing the order. As soon as you have finalized the details you can then proceed with making the payment for your paper. The timer for the delivery of your essay is going to begin as soon as you have completed the payment. Prices In terms of pricing, the price can range widely based on what services you have selected and the level of the paper and writer you have chosen. The most basic essay, which is a high school essay with a 15-day delivery will cost around $9.95 per 275 words or 1 page. This price is quite low, and it is not one many companies can compete with. From there the price goes up with every increase in the level of the paper, writer, extras, or decrease in the time you make. To put it simply, this is a highly adaptable pricing scheme that will ensure you will only pay for what you are using. Discounts 99Papers offers some discounts to users. Around the back-to-school period, they tend to offer some 15% off options, as well as the chance to win a free essay. This can help lower the price of this service overall. #2. PaperHelp PaperHelp is known for having a relatively better quality of writing than many other writing services. What has helped them grow a lot is their referral program which allows students and others to share their services to get a discount. Most often the grades of those who use PaperHelp tend to range from B- to A which can be good. For good results, it is also important that all of the requirements are communicated as the writers may not always be familiar with the topic on hand. How does it work? PaperHelp has an easy format that allows you to choose the type of writing you need. It offers academic writing, editing, and proofreading, as well as Calculations. This means that it can be used by those studying or working on any range of topics. From there you can actually select the number of words needed and the type of paper. More importantly, you can actually choose the exact time of the deadline. This means that you will never be late in submitting your own papers with PaperHelp. Prices The prices for an Academic paper start from $12. This is not only a low price but one that many students can afford to pay, especially for a paper that will normally get a high grade. This is a highly competitive price that becomes even better when one considers that they offer a number of discounts. Discounts For first orders, there is a 15% discount available usually. What’s more, when you refer others to the service you can get up to 10% off. This is another great way of saving money while getting your work done. #3. EssayBox EssayBox is one of the priciest writing services available, but that price often comes with an extremely quick turnaround. However, the quick pricing is not justifiable when one looks at the quality of the essays as many of the essays tend to be average. This means that it can’t compete with some of the top writing quality services that exist in terms of writing quality, but it can certainly beat them in how quickly they can deliver. How does it work? EssayBox works in pretty much the same way that every other writing service does. In fact, their opening page is pretty much the same as the page for 99Papers, only with one big difference, the pricing. The pricing tends to be quite a bit higher and can become even more costly based on the type of essay, the level of education, and the timeframe for delivery. Each page added will also add to the cost. In terms of the actual order page, it is exactly the same as the one 99 papers offer with the same extras available for priority support, a native speaker, a top writer, a plagiarism report, a copy of sources, a 1-page summary, and other options. Their extras are also priced similarly to the extras on 99 Papers which means you would not be spending much more on these, even though the price per page of each document is higher. Prices The lowest prices offered by EssayBox are for high school papers and they are around $12 currently. However, it should be noted that they have previously had the price for this type of service as high as $20. This is much higher than the price offered by some of its competitors as it is almost double the price. Discounts In terms of discounts, they offer a 15% back-to-school bonus that you can take advantage of. While this can definitely be helpful, it is similar to the discounts offered by other services and thus, does not help separate this service from other writing services available. #4. EssayPro EssayPro is a highly trusted writing service with excellent customer support that can help you get good essays in a quick timeframe. They offer several different writing services that include personal statements, dissertations, research, term papers, and several other options. They also offer several options for essays and even homework assistance depending on your needs. What helps set them apart is all of the extra steps that they take to ensure the quality of the writers that they are hiring. For every writer that they hire they verify their ID and diploma. They then proceed to request writing samples to see whether the writer would be a good fit for their company. Following the samples, they always send each potential writer test assignments to see whether they would be able to keep up with the workload required. Finally, they have a trial period during which they continuously monitor the writer’s performance. All of this allows them to ensure the highest quality of papers. How does it work? The first step to ordering is actually filling out their order form. This form will include information on the length of the essay you are looking for, the topic, and the level of the paper you need. You can also provide samples of your previous work in order for their writer to mimic your writing style. This will make your essay appear more like it is your own work. Once you have supplied them with as much information as possible you will then be called to decide on which writer you would like to receive help from. This will include you checking out their profile, seeing their area of expertise, and even chatting with them about your topic. All of this ensures you have the right fit. Finally, you place an order and pay a deposit. You are not required to pay the full price for the paper until the paper has been delivered. Revisions are also included in the price of the paper you are paying for. Prices Their lowest price is for 1 page of school-level writing, and it starts at $10.8. From there the price will increase based on the level of writing you need and the length of your paper. The delivery timeframe will also affect the cost. Discounts They don’t have any discounts noted on their website, but you might be able to find some by searching online. #5. Studdit Studdit is an affordable writing service that offers a money-back guarantee as well as a plagiarism-free guarantee. This makes it one of the safest options in terms of writing services that you can choose from. In general, they have a relatively easy process for those who want to place an order, which includes a simple calculator and a quick form for placing the order. They also provide an extensive FAQ with information about all of their different types of services. Studdit is not only a writing service, but rather it is focused on providing help with every type of academic work that a student might need assistance with including homework. This makes it slightly different than other services which are targeted only towards writing levels for high school students and beyond. How does it work? Studdit starts with a simple form that allows you to choose the length of your paper, the deadline you need, and the level of your education. From there you are given a price and the option to proceed. On the next page, you are called to describe your paper in detail. The level of details you want to provide is up to you, however naturally the less information you provide the less likely you will be to receive a good quality written paper from them. Much like with certain other writing services this is also the moment you can choose the level of writer you would like. Advanced writers and top writers are charged extra. Finally, there are also a few other extras to consider one of which is a Turnitin report. If you are worried about plagiarism, then this report can give you great peace of mind as Turnitin is the most commonly used plagiarism reporting tool by academics. Prices In terms of pricing, the lowest offers start from $13, much like with other services based on the choices you make on the form this pricing is likely to increase. You are also allowed to increase the price by selecting extras that include the level of service you want to receive. For better quality service you can include the VIP service at $14.99. Discounts Studdit often offers a few different promotions. Their standard one is 15% off of someone’s first offer but depending on the period you might find even larger discounts available. #6. SpeedyPaper SpeedyPaper is an online academic writing essay that allows a wide number of different writing services. These writing services extend far beyond writing, as you can also choose to have someone edit, rewrite, problem-solve, mark or even just proofread your essays and homework. The company works by hiring several different expert writers who are supposed to have a high level of expertise and can deliver quickly, even if the deadline is coming up shortly. How does it work? To place an order with SpeedyPaper, the first thing you need to do is to actually fill out their order form. This includes your subject, length of the essay, paper formal, and any other material you think is relevant to your order. This can also include some of your other original papers for the writers to get a better idea of your writing style. Once you have made all of your selections through the order form you can proceed with the payment for your order. Prices The lowest price available on SpeedyPaper is $11, this price changes based on the type of services you are going to be including in your paper. It also includes free revisions which are fulfilled by their round-the-clock support. Discounts SpeedyPaper actually has an entire discounts page on their website which you can use to find discounts applicable to you. These usually include: First-time order – 11% off; Referral offer – You get 10% off for every friend you invite that joins. Your friend also benefits from 10% off; Labor Day offer – 15% off; Youth Day offer – 12% off; Independence Day – 15% off. #7. EssayFactory EssayFactory is a writing service that specializes in the UK market. This means that if you need an essay that is written in excellent British English, then it might be one of your best options. Their service is often noted to have very prompt delivery, and it appears to be a reliable service that provides excellent essays to all those who purchase. They also provide editing services to those who don’t want to have a custom-written essay. How does it work? The first step in the essay factory process is filling out the form. This form is similar to the one that other websites like 99Papers use, with one simple difference. All of the academic levels have been adaptable and changed to better represent the UK school system. This means that you can choose A1/A2 for A-level courses or a university level. Prices In terms of prices, they can start as low as £ 11.50 but can increase in price tremendously based on the time frame of delivery and the level of writing you need. They also don’t offer as many different extras that can elevate the price of the service you will be receiving. Discounts EssayFactory has several different discount codes that are always available on their website. These include a 25% off discount code, and an offer where you can get your 5 th assignment for free if you have paid for it. Or that you can book 6 assignments within seven days to get the seventh assignment for free. They also offer several 10% and 15% percent deals that you can take advantage of to lower the price you will need to pay for your essay. #8. 1Essay 1Essay is a relatively good and affordable essay writing service, however, where it suffers is in providing consistent results to its users. While they can always supply a custom essay in time their services are not always rated in the best possible way. This is also in part because they don’t offer as many options both in terms of a delivery timeframe as well as in terms of the type of academic work that they take on. The combination of these two factors can often mean that many might not be able to find the type of service that they need through 1Essay. How does it work? To use the 1Essay platform, you will need to first get a price estimate based on the type of paper you need. This means filling out the order form with the information relating to both the level of education this paper will relate to, as well as the timeframe for delivery. The fastest delivery that 1Essay offers is 24 hours, so if you are in too much of a hurry this service will not be able to assist you with the work you need. Prices In terms of pricing, the prices start at $9, which is lower than the price offered by 99 Papers. This makes it one of the most affordable services. However, that low price can quickly be elevated if the paper you need is anything above a high school-level paper. They also offer several extras that can also cause your paper’s price to increase. Discounts 1Essay does not offer a comprehensive list of discount codes in the way that other similar websites do. This means you will need to try and see if any coupon codes exist online at the time of placing your order. #9. IQEssays IQ Essay is a relatively affordable academic writing service that is focused on providing good quality essays. They claim that what helps set them apart is that they ensure that all of the essays they deliver have flawless quality. They also claim that all of the work they provide and all of their client’s information is completely confidential. They provide a confidentiality guarantee for their services. How does it work? Using their service is quite simple as all you need to do is fill out their order form with information about your assignment. From there they are going to assign your task to a writer who will be responsible for delivering the work on time. You are also going to be able to directly contact that writer whenever you need to ensure that the paper ends up being as you envisioned. Prices Their prices range from $10 per page to $58 per page depending on the level of education you require and the timeframe for delivery. The fastest delivery of a college-level paper is 3 hours, while everything from undergraduate degrees to Ph.D. requires a one-day delivery at least. Discounts IQEssays offers a 5% discount code on the first order. This is a much smaller discount than the one offered by most academic writing services. #10. PaperCoach PaperCoach is an extremely popular service that has been used for over 32,000 orders. This large number of orders is also an exhibit of the highly experienced writers that they have on board. According to their website, they currently employ more than 1300 writers and their satisfaction results are 98%. More importantly, through their website, they offer a wide range of different types of academic writing. These include: Essay (any type); Dissertation; Research paper; Application letter; Case study; Book review; Term paper; Problem-solving; Coursework; Personal statement. How does it work? PaperCoach has a relatively simple process for placing orders. The first thing you need to do is fill out their form with all of the details of what you would like your order to be on. Then you can select your payment type and even place an order. It is as simple as that. Within the delivery timeframe you have specified, you should expect to get a paper that is not only flawless but also 100% plagiarism-free according to PaperCoach. Prices Their prices truly have a large range going from $7.99 for a High School paper in 14 days, to $66 for an admissions essay in 6 hours. They are also able to offer their services with delivery as quick as 6 hours. This includes Ph.D. work and academic papers. Other costs include the inclusion of a pro writer for 25% more or a top writer which comes with a 45% added cost to your order. Discounts Currently, PaperCoach doesn’t appear to offer any discounts, but that might change in time which is why it is always best to check. Still, even without a discount, their prices are some of the most affordable on the market. #11. Ivory Research Ivory Research is a UK writing service that has been in action since 2005. During that time, they have been helping students with everything from short essays, to dissertation work to exam preparations. As they claim, they are focused on helping students reach all of their academic goals. They offer 24/7 support for all of their services and can guarantee that the work provided will be plagiarism free. How does it work? In contrast to how many other services work, in this particular writing service you first need to decide what type of essay you would like to receive. From there you will be taken to a page that will allow you to choose the word count, delivery grade, and more importantly the grade you want to achieve. This page is targeting UK students, so all of the grading requirements are going to be based on the British educational system. Prices The prices can widely vary for this service as it depends on the type of grade you want to achieve. For example, a 1000-word essay that will get a 2:1 will cost around £132. There are often discounts included that can help lower this price. Discounts A few promos run on the website at different times. There are no set discount codes. #12. WiseEssays Wise Essays is an easy-to-use affordable writing service for students. Their service is similar to the service offered by 99Papers and other top writing services in that it all works through requesting the topic and essay length you need. Their platform is fairly easy to navigate, and their competitive pricing often helps set them apart. How does it work? To get an essay through wise essays the first step you will need to take is to fill out the form. One of the unique aspects of this is that you can actually request a specific writer. This is extremely useful if you had previously collaborated with one of their writers and know that you can work well with them. Once you have confirmed all the details of your assignment you can proceed to the payment page and place your order. Prices The prices for this service start from $9.11 but depending on the level of writing, timeline, and word count you will get different prices. More importantly, different writers might require different amounts for their work. Discounts There are currently no discounts available on their website. #13. SuperbPaper SuperbPaper is a 24/7 essay writing service that can assist you with all of your essays whether you are in high school, college, or university. In general, they are considered to be a relatively affordable priced service and their website is very easy to navigate and well-designed. This has slowly been helping them establish a better name for themselves in the world of college essay writing services. How does it work? To place an order, you will need to complete the order form. Their one form includes all of the details relating to their service as well as the paper instructions you want the person writing the essay to follow. You can also use the number of sources and style format which can be incredibly important in academic papers. Prices Their prices start from $10 and adjust based on your requirements. Discounts They offer a 5% discount on the first order one places with them. #14. HomeWorkforMe HomeWorkForMe is not just focused on essays, but rather it is more focused on helping people complete their homework successfully every single time. They can guarantee both that their prices are affordable and that every delivery made online is going to be secure. For those who are wearier when placing orders online, they also have a 100% money-back guarantee that can help ensure they will be getting their money back when and if needed. How does it work? The way this service works is different from the way other essay writing services work, as instead of the type of essay they make you choose the subject you need help with. From there they will help you with whatever homework you have in that particular subject. Before they provide you with the essay paper requested, they will also be performing a free plagiarism check. This is different from most other companies as plagiarism checks are usually an extra charge. Prices In terms of pricing, orders start from $17.55, which makes it one of the most expensive services available. Discounts Currently, there are no discount codes available for their services. #15. MyAdmissionEssay In contrast to its name, MyAdmissionEssay does not just focus on admission essays. Instead, they can assist with essays at every level, including high school, undergraduate and professional. Over the years they have fulfilled 141,453 orders and have had more than 30 thousand returning clients. They also have over 3,500 degreed writers on their team. How does it work? To place your order with them, you will first need to fill out their order form. This is a standard order form that will help determine the price of the paper. From there you will be called to fill in your details and then make a payment. Prices Prices for this service start at $14 and go up from there depending on the timeframe for delivery, type of service, and academic level. Discounts There is a 5% welcome discount bonus for those who first join the platform. Frequently Asked Questions What is an essay? An essay is a specialized piece of writing that relates to any particular topic. Normally essays are shorter in length than books but can still provide insight into the topic at hand. They are commonly used in academic settings, but they can also be used outside of them. More importantly, though, most essays will need to have some specific goals that they meet. These relate to the content, format, and argumentation used in essays. Normal essays, whether academic or not, will often present some factual evidence for what is being written. This evidence can be limited, and in the cases of argumentative essays, or critical analysis essays they might entirely relate to the experience of the writer. Outside of presenting some evidence on the subject that the essay is dealing with though, it is also incredibly important for an essay writer to present their own point of view. The extent to which they can do that will depend on the type of essay they are writing. There are four types of essays: discursive, persuasive, narrative, and descriptive. In academic essays, the title of the essay will give you information on which type of essay you should attempt to write to be successful and graded well. How long should an essay be? The length of an essay will greatly vary based on the purpose of the essay. If you are in an academic setting oftentimes the length of the essay will entirely be decided for you. What that means is that your professor will set forth an assignment for an essay that is 500 words long or 1000 words long. In those cases, you should always try to abide by the length that your professor or teacher has set forth. This is particularly important because in many cases, longer essays will get penalized as they don’t fit the criteria set forth. If you have to write an essay, but the length of the essay has not previously been defined by someone else, then you shouldn’t focus too much on deciding the length of the essay ahead of time, so long as your essay does have the following three things. An introduction that covers your topic, gives the reader an idea of what you will be presenting and your perspective or opinion on the topic. A body of text that is at least two to three paragraphs long and explains every point made in the introduction with evidence, as well as your own perspective or opinion. A conclusion that summarizes the text and the main key points and conclusions you reached through your analysis and argumentation. How to write a good essay? Writing a good essay can be easy if you know what to focus on. To make this a little bit easier for you, we are going to break down what a good essay requires step by step. Title The title is often forgotten, however when it comes to successful essay writing, having a valid title or topic that presents the key question or idea of what you are trying to achieve can be key. Your title will also give your ideas about which the type of essay you are looking to write. For example: “Analyze the causes of World War One and their effects.” Is an essay topic that will require a lot of presenting of facts, but your opinion on these facts will not necessarily need to be presented extensively. On the other hand, the following topic: “Evaluate the causes of World War One and their effects,” Requires you to extensively look at the topics and present them in order of importance based on your opinion. The second essay topic will thus require a lot more argumentation. This is why having the right essay topic title is the key to knowing the type of essay you should try to write. Introduction Your Introduction should give the reader your entire essay at a glance. Start with a sentence that captures the attention and imagination of the reader. Then continue by presenting in a few sentences a small part of the context for your essay. From there add a short line presenting each of the topics you will cover in your essay. Finally, end your introductory paragraph with a statement showing the position you will take and the point you will try to convince the reader of by the end of the essay. Body of text Your body of text will be made up of many paragraphs. You should have one section for each of the points you said you would raise in your introduction. Each section can have several paragraphs depending on your topic. When building your paragraphs, you will need to focus on: Your opening line – this presents the main idea of the paragraph; Your idea – the point you are presenting in a theoretical way; Your facts and data – this is the evidence that supports the point you are making; Your argument; Your conclusion to the paragraph – this should link you to the next section or paragraph. Conclusion Finally, your conclusion needs to show an overview of everything you presented in your essay as well as the argument you reached. Your conclusion along with your introduction needs to be perfectly written and present your entire essay. Just by reading your Introduction and conclusion, someone should be able to know exactly what your essay is about. If you are struggling with writing your essay, then you can also try hiring essay writing services from the top 15 best essay writing services presented above. This can help you guarantee the quality of your final essay. How long is a 1000-word essay? A 1000-word essay is a very standard size of essay in the academic world. Normally it is around four pages long with Times New Roman size 12pt and double spacing. These are all standard formatting requirements for essay writing, so when you are writing your essay you will know that around the fourth page is when you will hit 1000 words. In terms of length, 1000 words are considered to be a rather short piece of writing, with most academic assignments usually being much larger. This is because in 1000 words it is hard to analyze topics extensively. In fact, for essays of 1000 words, you can get away with only having two points of analysis and you should never try to fit more than 3 points in a 1000-word essay. If you are trying to decide how many paragraphs your 1000-word essay should have then, a good amount is between 5-10 paragraphs. This of course will depend on the length of each of your paragraphs. For example, your introduction should be around 200 words and your conclusion should similarly be around 150 words. This leaves you with about 650 words for the body of your text. This means that 5 paragraphs of approximately 100 words will help you reach your word limit. How many paragraphs are in an essay? The number of paragraphs in an essay will widely range depending on the size of the essay you are writing. A good rule of thumb is to remember that your introduction will take up between 100-200 words. If you can manage to keep every single paragraph within that realm, then you should be able to know the approximate number of paragraphs for your essay. In shorter essays, like a 500-word essay, for example, your introduction might be only 50-80 words. This would like you around 400 words for the conclusion and body. Assuming the conclusion is around 80 words, then each of your paragraphs should not be much longer than 100 words. This means that overall, you would have about 5 paragraphs in your entire essay. A much longer essay might require a more complex introduction that covers a lot of the theoretical framework necessary for the understanding of the essay. If that is the case, you might find that the introduction is an entire section, rather than a single paragraph. For example, in a 1000-word essay, your introduction might be around 500 words and depending on your subject this could be completely normal and acceptable. This once again goes to show that the number of paragraphs in an essay will vary based on not only the length of the essay but also the subject. What is the popular essay writing styles (formats)? Outside of writing your essay you most likely will also have to deal with citations. Citations and references can often feel complicated at first but will become much simpler once you start understanding what different formats exist and when they are used. Essentially a citation style is a way in which you will present the credit to the person, book, document, or source you took the information from for your essay. This gives you the right to talk about their work without claiming it as your own. If you are in an academic setting, then the citation style you will need to use may be predetermined by your professors or university. Some citation styles are more commonly used in certain subjects. The three most common citation styles are: APA (American Psychological Association) is often used in the following subjects, Education, Psychology, and Sciences; MLA (Modern Language Association) often used in the Humanities; Chicago/Turabian style often used in the following subjects, Business, History, and the Fine Arts. How to write an essay fast? If you are in a time crunch and you are trying to write an essay fast, then the first thing you will need to do is quickly skim-read a few sources. While looking at these sources you should copy and paste and make notes on any important section that you want to use for your essay. You should also write the citation for the book or document you are using right next to the facts you are writing; this will help you create your bibliography faster. From there you should look at the information you have gathered and make an outline of the two or three key points you want to make; you should also categorize the sources and information you have in each one of these sections. Once you have a clear idea of your points and arguments you can start writing. To write fast you should try to complete your entire draft without making any corrections. Then go back and edit your essay accordingly, this will allow you to progress with your essay much faster. If you can’t complete your essay on time, you can also hire a good essay writing service to complete the essay for you in a swift time frame. These professional writers often have extensive experience that allows them to complete essays much faster than other people can. How to write a "why nyu" essay? If you are trying to write a “why nyu ”essay the first thing that you need to understand is that this essay prompt is not asking you why you are choosing to study in New York, but rather what has drawn you to the specific program and area that you want to study and why you think NYU is the best college for you to study your chosen topic. To write this essay therefore you will need to look at which aspects of the NYU mentality, curriculum, and teaching style matches you. For example, if the NYU program you are considering is very team-based and hands-on, and you know that you will thrive in that type of program, while you would stagnate in a theory-based program then you should talk about that. You should also mention which parts of the curriculum seem like a particularly good fit and how you think you think the academic environment and NYU community will help you reach your full potential. What is the best essay writing service overall? 99Papers is the best essay writing service overall. The reason for this is that they manage to combine quality with affordable prices. This is something many other services are not able to do as they are either more expensive or they offer writing services that are of the worst quality. Another reason why 99Papers is the best is the ease of use of the website. They offer one of the easiest platforms for placing orders which can be especially important in a time crunch. Finally, when you are in a pinch, they can deliver your orders in 3 hours when many other services would need 6 hours or even 24 hours. What is the best custom essay writing provider? PaperHelp is the best option for those who want custom essays. This is because while their prices are a bit higher, their writers are of impeccable quality. This means that no matter what topic you require from them they will be able to deliver incredibly well-written work within the time frame requested. With the revisions available you are also going to be able to get the quality of the text to be exactly where you want it to be. This can be extremely important if you don’t want to end up with an essay that doesn’t reflect your writing style. Therefore, for highly customized essays the best option is PaperHelp. What is the cheapest essay writing company? EssayPro is the most affordable essay writing company when one looks at all of its services. Their cheapest service which is editing starts at $6.75. This price is tough to beat as many other editing services will cost closer to $9-10 dollars. More importantly, though, they are the only service that their prices don’t get completely inflated when it comes to postgraduate and Ph.D. level work. Their High School and College level articles are similarly priced at $13.5 per page and $14.25 respectively, while both their master’s and Ph.D. work cost exactly $19.25 per page. This is much cheaper than the $25+ requested for Ph.D. work by other writing services. What is the best UK essay writing service? EssayFactory is the Best UK essay writing service. This is because their work is entirely focused on the UK. As a result, they separate essay types and levels using the grading for the British system. While this might not appear important at first glance it is crucial as each grade level is marked differently in the British system. By only working with British students, they have adapted their services so that they can work best with the UK mark scheme. Knowing how the mark scheme for the country or institution you are writing an essay for works can be essential as it allows you to customize your essay more deeply and ensure that you are meeting all of the requirements set forth. This is something that EssayFactory understands and does to an incredible extent for UK students. Are essay writing services legit and safe? If you are worried about the legitimacy of writing services, then you might want to look into which writing services you are choosing. While there is always a chance of someone claiming to offer a service that they are not capable of offering, that is not commonly the case with writing services. All of the writing services presented in this article are completely legit and safe to use. This means that when you are ordering from their website you can feel certain that you are going to be receiving exactly the type of essay or writing piece that you have requested. What’s more, many writing services offer money-back guarantees and even refunds, which just goes to show you how much these businesses are not only legitimate but also deeply care about providing their customers with the best possible experience that they can. Therefore, whenever you are ordering an essay, or any other writing service makes sure to do it through a reputable service. That way you will be guaranteed to get exactly what you have paid for both in terms of quality and length of the essay. How to find a professional essay writer? The easiest way of finding a professional essay writer is to visit one of the top 15 best writing services that we have presented above. All of the writers in the above section have years of experience and they can deliver high-quality work in a very short time frame. More importantly, most of these websites will vet the writers before they allow them to be part of their services. Therefore, there is always quality assurance in choosing any one of these writers. If you are looking through these websites for a professional writer and they offer you different options, but you are uncertain of whom to choose then there are a few things for you to consider. Topic Many writers will have a certain expertise on one topic. For example, if you are a Chemical engineer and you require an essay on a certain chemical procedure then you don’t want someone with a degree in English literature to complete your essay. This is mainly because they won’t know all of the terminology and aspects of your field. Therefore, always choose someone with expertise in your subject. Level of Expertise Normally, one of the things disclosed regarding each writer is their level of expertise. If you are writing a highly specialized topic, then you might need someone with more years of experience or even a higher educational degree. This is also something to consider when choosing the right writer. In the end... If you are trying to always have good quality essays, then one of the easiest and best things to try is to hire professional write my essay services with discounts. These services will be able to provide you with the best quality of writing on any topic you require. In part this is because they have a wide range of different writers available and each one of these writers will often have a different educational background and level of expertise. This will allow them to tackle any topic you require on the level necessary. Not only that, but they will also be able to complete the task of writing your essay to the highest standard. This will save you time in both research and writing as someone else will be doing that work for you. You can then read your essay and submit it quickly. This can be perfect for all of those times when you might need to submit an essay, but you are running out of time. To hire a reliable writing service, we recommend choosing one of the top 15 writing services presented below. They will be the perfect solution for to you get incredible results in a very short timeframe. Contact Details Writing Solutions Will Collins contact@best-essay-services.com Company Website https://best-essay-services.com

October 06, 2022 01:34 PM Eastern Daylight Time

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Fullintel Shortlisted For Five 2022 AMEC Awards

Fullintel, LLC

Fullintel, a leading media monitoring services company that specializes in human curation combined with powerful predictive intelligence, is pleased to announce it has been shortlisted for five 2022 AMEC Awards: Best use of social media measurement (2) Best crisis communications measurement and reporting Best use of measurement for a single event or campaign Best use of integrated communication measurement and research “As media becomes more fragmented and difficult to track, awards programs like AMEC’s are even more significant because they showcase how industry leaders like Fullintel are able to cut through the noise and find the content that matters,” said Fullintel President Andrew Koeck. “Our award-winning media analysis builds on this, providing our clients with strategic advice and customizing our reporting to address their specific objectives, resulting in actionable insights to drive their PR strategy to improve business results.” In the last two years, Fullintel has won four AMEC Awards including Gold for Best Multi-Market Reporting for their client at HelloFresh. The news comes on the heels of Angela Dwyer, a former senior vice-president at NYC-based PR agency Lippe Taylor and senior project manager at PRIME Research (now Cision), joining Fullintel as Head of Insights to further accelerate its media analysis program. As a member of the IPR Measurement Commission, Angela contributes to the development and promotion of standards and best practices for research, measurement, and analytics with a recognized global group of professionals in the industry. Her best-in-class measurement experience with solid research approaches will continue to elevate Fullintel’s work to help clients measure impact and make smarter business decisions – leading to better, award-quality results for clients. The 20th annual AMEC Awards is a global awards program for communications measurement held by the International Association for the Measurement and Evaluation of Communication (AMEC). The program highlights exceptional work while highlighting the vital importance of measurement, research, and analytics. Fullintel works with the world’s largest brands to offer daily executive news briefs, real-time media monitoring, and award-winning media analysis covering all traditional and social media platforms. Our real-time media monitoring service monitors every media source available, and Fullintel Hub's PredictiveAI™ engine will alert your team up to 48 hours in advance of trending stories that will become viral. You can view the full 2022 AMEC Awards shortlist here. About Fullintel: Fullintel offers a unique combination of talent, tools and technology for PR professionals looking for media monitoring and PR analysis services. We’re not just an app with canned reports - we tailor custom experiences for each client. Our reports feature easy-to-understand analysis that our clients leverage for continuous improvement, and are delivered with the accuracy, speed, relevancy and intuition that only trained industry analysts could provide. Contact Details Fullintel Samuel Chen +1 339-970-8005 schen@fullintel.com Company Website https://fullintel.com/

October 06, 2022 08:52 AM Eastern Daylight Time

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Fortress Bio’s Portfolio Of Marketed Drugs Could Soon See Three Additions

Fortress Biotech, Inc.

Fortress Biotech Inc. (NASDAQ: FBIO) is a biopharmaceutical company focused on developing a range of high-potential treatments on its own and through its growing portfolio of subsidiaries and partner companies. With nine products already on the market and more than 30 programs in development, the biopharmaceutical company helps deliver innovative drug therapies to patients who have a wide range of diseases and disorders. Here are three of the most significant breakthrough developments it achieved this year. Checkpoint’s Cancer Immunotherapy Aims To Add Second Treatment Indication Checkpoint Therapeutics Inc. (NASDAQ: CKPT) announced positive interim results in June from a registration-enabling clinical trial of its anti-PD-L1 checkpoint inhibitor. The novel cancer immunotherapy is being studied as a possible treatment for advanced cutaneous squamous cell carcinoma (cSCC), a difficult-to-treat skin cancer. The current first-line treatment for cSCC is surgery to remove the tumor or radiation therapy to destroy the tumor. However, some patients aren’t candidates for surgery or radiation, either because of poor health or because cancer has spread or become too advanced. Cosibelimab is an immunotherapy drug that works by blocking the PD-L1 inhibitor, an immune checkpoint inhibitor on the surface of cells that tells the body’s immune system not to attack that particular cell. Cancer uses those same checkpoint inhibitors to trick the immune system into believing the cancerous cell is a normal healthy cell that it should not attack. By blocking PD-L1, cosibelimab can remove cancer’s ability to escape detection and allow the patient’s own immune system to better identify and attack cancerous cells. In the registration-enabling clinical trial, cosibelimab achieved a response rate of 54.8% — far exceeding the minimum 25% target. Checkpoint plans to discuss the potential of adding locally advanced cSCC as a second indication in addition to metastatic cSCC with the Food and Drug Administration (FDA) as it prepares its biologics license application for submission around year-end. Checkpoint provides a 4.5% royalty on net sales and a 2.5% annual equity dividend to Fortress Bio in exchange for its operational, strategic, administrative, financial, and legal support. A First-Of-Its-Kind Menkes Disease Treatment Edges Closer To FDA Approval Last year, Cyprium Therapeutics Inc., a Fortress Bio partner company, announced the initiation of rolling submission of its new drug application (NDA) with the FDA for its novel treatment for Menkes disease. The company presented additional data in March at the 2022 American College of Medical Genetics and Genomics (ACMG) Annual Clinical Genetics Meeting. Cyprium continues to progress toward the completion of its NDA submission. Menkes disease is a rare but fatal genetic condition that impairs the ability to transport copper through the body. This results in abnormally low levels of copper in the brain and liver along with abnormally high levels in the kidney and intestines. Symptoms include poor muscle development, low weight, and cognitive difficulties. The difficult-to-diagnose progressive disease has no approved treatments, and most children with Menkes disease will die within the first three years of life. CUTX-101 is a copper histidinate (CuHis) injection that can be administered directly into the body to restore copper levels. Because Menkes disease affects the body’s ability to absorb copper through the gastrointestinal tract, direct injections are meant to bypass the GI tract and deliver copper straight to the bloodstream. Clinical data showed that CUTX-101 improved neurodevelopmental outcomes and survival in treated patients, including a nearly 80% reduction in the risk of death. If approved, CUTX-101 has the potential to be the first FDA-approved treatment for Menkes disease. As with Checkpoint, Fortress Bio receives a 4.5% royalty and 2.5% annual equity dividend from Cyprium. A More Potent Oral Rosacea Antibiotic May Offer Lower Risk Of Treatment Resistance Journey Medical Corp. (NASDAQ: DERM) is a dermatology biopharmaceutical company founded by Fortress Bio. Journey announced 50% enrollment in its Phase 3 clinical trial of a novel rosacea treatment in August. DFD-29, the drug candidate being studied in the clinical trial, is a minocycline-based compound meant to treat rosacea using its anti-inflammatory and antimicrobial properties. Minocycline is already used to treat other inflammatory conditions ranging from acne to rheumatoid arthritis because it can block pro-inflammatory cytokines and other inflammatory processes that cause flare-ups. It’s typically administered as a topical treatment, which can help with milder symptoms but doesn’t provide enough relief for severe cases. Doctors typically prescribe a course of doxycycline for rosacea patients with severe flare-ups. But the clinical data on DFD-29 showed that it was almost twice as effective as doxycycline at reducing lesions and overall symptom improvement. DFD-29’s modified release capsule is also meant to counter the bacterial resistance that often develops with frequent antibiotic use. Rather than immediate release, the capsule slowly releases small doses of minocycline over time. The subantimicrobial dose is meant to be low enough to avoid triggering selection pressure for bacterial resistance while still offering the anti-inflammatory benefits of the treatment. Topline data from this latest Phase 3 clinical trial is expected in the first half of 2023, and the company expects to file a new drug application by the end of that year. Fortress Bio currently owns a controlling stake in Journey Medical. Fortress Biotech, Inc. ("Fortress") is an innovative biopharmaceutical company focused on acquiring, developing and commercializing high-potential marketed and development-stage drugs and drug candidates. The company has nine marketed prescription pharmaceutical products and over 30 programs in development at Fortress, at its majority-owned and majority-controlled partners and subsidiaries and at partners and subsidiaries it founded and in which it holds significant minority ownership positions. Such product candidates span six large-market areas, including oncology, rare diseases and gene therapy, which allow it to create value for shareholders. Fortress advances its diversified pipeline through a streamlined operating structure that fosters efficient drug development. The Fortress model is driven by a world-class business development team that is focused on leveraging its significant biopharmaceutical industry expertise to further expand the company's portfolio of product opportunities. Fortress has established partnerships with some of the world's leading academic research institutions and biopharmaceutical companies to maximize each opportunity to its full potential, including AstraZeneca plc, City of Hope, Fred Hutchinson Cancer Research Center, St. Jude Children's Research Hospital, Nationwide Children's Hospital and Sentynl Therapeutics, Inc. This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Jaclyn Jaffe and Bill Begien +1 781-652-4500 ir@fortressbiotech.com Company Website https://www.fortressbiotech.com/

October 06, 2022 08:00 AM Eastern Daylight Time

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Understanding the Importance of Lowering Your Cholesterol to Help Decrease Your Risk for Heart Disease

YourUpdateTV

A video accompanying this announcement is available at: https://youtu.be/_EQumoCuW6U High cholesterol is the single biggest cause of illness and death in America affecting more than 94 million adults in the United States, according to the Centers for Disease Control and Prevention. For some people, it is their genes that lead to very high LDL (“bad”) cholesterol. One of the most common causes of genetically high cholesterol is familial hypercholesterolemia (FH). FH impacts 1 in 250 individuals worldwide, and if untreated it leads to early heart attacks and strokes. There are already decades of research showing that high LDL cholesterol is a major risk factor for heart disease. And recent data has shown that having lower LDL for longer is one of the best things people can do to reduce your risk for heart disease. While a healthy diet and exercise are important for many reasons, diet and exercise alone cannot lower many people’s cholesterol to a safe level, especially if they have a genetic cholesterol-related disorder. There are medications that can significantly reduce the level of cholesterol in the bloodstream. Statins are the first line of defense when it comes to getting your LDL-cholesterol to a safer level. A new study on the safety and effectiveness of statins shows the vast majority of people do not have side effects from statins, and they not only reduce the LDL cholesterol, they also reduce the risk for heart attacks and cardiac death. The American College of Cardiology also just updated its expert guidance for medical experts treating patients and suggested an LDL target of less than 55 mg/dL for individuals with established cardiovascular disease. The Family Heart Foundation has a variety of resources for understanding treatment options for lowering high cholesterol and treating FH. Visit MoreFamiliesMoreHearts.org to learn more. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

October 04, 2022 03:00 PM Eastern Daylight Time

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US Digestive Health Expands Presence into Delaware Through Partnership with Delaware Center for Digestive Care

US Digestive Health

US Digestive Health (USDH), a network of top-rated gastrointestinal (GI) practices managed by US Digestive Health Management (USDHM), a management services organization created to expand access to high-quality, cost-effective gastroenterology care, announced today that it has partnered with Delaware Center for Digestive Care (DCDC), a specialty practice based in Newark, Delaware. The partnership with DCDC will bring an additional three locations, two ambulatory surgery centers, over 35 providers, and more than 140 employees to the US Digestive Health Management network, further positioning USDH as the leading GI practice in the Northeast. With the addition of this new partnership, US Digestive Health Management now oversees a network of over 200 gastroenterology professionals and service providers, along with 29 locations, 17 ambulatory surgery centers, and over 950 employees. US Digestive Health Management works hand-in-hand with gastroenterology partner practices throughout Central and Southeastern Pennsylvania, Western Pennsylvania, and now Delaware, to meet the challenges inherent in the fast-changing healthcare landscape. USDHM provides innovative business management and technology solutions that ease administrative burdens and allow physicians to focus on clinical care. “USDH brings the type of high-quality care, elevated standard of medicine, innovation in diagnosis, and treatment our patients deserve,” added Dr. Mark Corso, DCDC Physician Board Member. “Through this partnership with USDH, our team of board-certified GI doctors and specialists can focus on patient care,” said Dr. Jared Hossack, DCDC Physician Board Member. “DCDC has established a strong reputation in the Delaware market as a preferred gastroenterology provider, and the practice has proven its commitment to patients by offering innovative options in the GI field while prioritizing patient-centric care. USDH is proud to join with DCDC and to serve the people of Delaware,” said Jerry Tillinger, CEO of US Digestive Health Management. USDH was formed in 2019 by Amulet Capital Partners, LP (“Amulet”), a middle-market private equity investment firm based in Greenwich, CT, focused exclusively on the healthcare sector, in partnership with member practice partner physicians. “We are excited to see USDHM expand to the Delaware region and add yet another industry-leading GI practice to its partnership network,” said Gabriel Luft, Partner at Amulet. “DCDC exhibits the type of patient experience and innovative approach that USDH looks to provide for patients across both Pennsylvania and Delaware.” Provident Healthcare Partners (“Provident”), a leading healthcare investment banking firm, advised DCDC on the partnership. For more information, please visit https://usdigestivehealth.com/. About US Digestive Health US Digestive Health (USDH) is the leading gastroenterology practice in the Northeast. USDH was formed in 2019 by Amulet Capital Partners, LP ("Amulet"), a healthcare private equity investment firm based in Greenwich, Connecticut, in partnership with member practice partner physicians. USDH aims to deliver high-value, patient-centric digestive healthcare by bringing new insight into the care, treatment, and prevention of digestive health disorders. USDH consists of 29 locations, 17 ambulatory surgery centers, over 200 GI providers, and more than 950 employees throughout Southeastern, Central, and Southwestern Pennsylvania, and Delaware. About Amulet Capital Partners, LP Amulet Capital Partners, LP is a middle-market private equity investment firm based in Greenwich, CT, focused exclusively on the healthcare sector. Amulet seeks to achieve long-term capital appreciation through privately negotiated investments in companies. Amulet Capital Partners focuses on those segments it believes have the most attractive long-term fundamentals with a target investment size generally between $25 million to $150 million. For additional information, please visit www.amuletcapital.com. Contact Details US Digestive Health Lauren Stralo +1 484-747-9692 lstralo@levlane.com Amulet Capital Partners, LP Jon Keehner / Erik Carlson +1 212-355-4449 Company Website https://usdigestivehealth.com

October 04, 2022 10:00 AM Eastern Daylight Time

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