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Smart Money is Quietly Loading Up On This $160M Oncology Stock — Is Nuvectis Pharma the Next Breakout Biotech? (NASDAQ: NVCT)

Global Markets News

In a market where noise often overshadows substance, Nuvectis Pharma (NASDAQ:NVCT)* is delivering a signal that’s hard to ignore — sustained insider buying by one of the company’s most informed and sophisticated investors. On June 20, 2025, Charles Mosseri-Marlio, a well-known biotech investor and former pharmaceutical executive, filed a Form 4 disclosing the purchase of 33,442 additional shares of NVCT at $8.05 per share. The $270,000 transaction adds to his already significant position, which now totals just under 3 million shares through Emerald Hill Capital. This marks the third major insider buy by Mosseri-Marlio in 2025 alone — with previous purchases in February and May at lower price points. The pattern is clear: this is not opportunistic trading, it’s strategic accumulation. What makes this even more notable is Mosseri-Marlio’s background. He previously held a leadership role at Flamel Technologies (now Avadel Pharmaceuticals), where he helped secure development deals with top-tier partners like Pfizer and GlaxoSmithKline. He’s not only familiar with drug pipelines — he’s built them. Combined with a track record in institutional asset management, his buying carries more weight than your average insider move. He’s not chasing momentum — he’s betting on execution. And there’s plenty in the Nuvectis pipeline to justify that bet. The company is currently advancing two first-in-class oncology candidates — NXP800 and NXP900 — both of which are in clinical trials targeting cancers with high unmet need. NXP800 is in Phase 1b development for ARID1a-mutated, platinum-resistant ovarian cancer — a devastating subtype with few effective treatments. The drug has already earned Fast Track and Orphan Drug designations from the FDA, streamlining its development and signaling strong regulatory support. Data from this trial is expected later this year, and could be a key near-term catalyst. NXP900, meanwhile, is designed to address drug resistance in advanced cancers, including non-small cell lung cancer. By inhibiting SRC and YES1 kinases, NXP900 targets the very mechanisms that allow tumors to escape the effects of EGFR and ALK inhibitors — two of the most common first-line treatments in NSCLC. After completing its Phase 1a study, the company is now preparing to launch combination trials that could demonstrate its potential to restore drug sensitivity in resistant tumors. Despite these promising programs, Nuvectis remains deeply undervalued relative to peers. The company’s market cap sits around $150 million — a fraction of other precision oncology players at similar stages. Nuvalent (NASDAQ: NUVL), for example, trades north of $6 billion with programs focused on the same indication space. Summit Therapeutics (NASDAQ: SMMT), which also targets drug-resistant cancers, surged to nearly $15 billion in valuation earlier this year following a pivotal trial result. Nuvectis isn’t there yet — but if it delivers on either of its two clinical programs, it may not be far behind. Importantly, the company is financially stable. Nuvectis raised $15.5 million in early 2025, bringing its total cash reserves to nearly $30 million as of March. That provides runway into 2027, giving it ample time to reach key milestones without returning to the market for funding. It also means less dilution risk — a crucial factor for investors in early-stage biotech. This backdrop of strong insider ownership, solid financials, and high-impact drug development is what makes the Mosseri-Marlio buying spree so compelling. He’s not the only one with conviction either — CEO Ron Bentsur and other insiders continue to hold sizable stakes and have not sold a single share. Bentsur, notably, has a track record of taking biotech companies through FDA approval and delivering real value to shareholders. Year-to-date, NVCT is up significantly but it’s still relatively under the radar. That may not last long. With clinical data expected soon, strong internal alignment, and one of the most experienced insider buyers in the sector continuing to build his position, Nuvectis Pharma may be one of the few small-cap biotechs positioned for a breakout in the second half of 2025. - News Highlights from Nuvectis Nuvectis Pharma, Inc. Reports First Quarter 2025 Financial Results and Business Highlights Nuvectis Pharma Provides Poster Presentation Highlights for NXP900 from the 2025 AACR Meeting Nuvectis Pharma Announces Upcoming Presentations for NXP900 at the 2025 American Association for Cancer Research Meeting - * Paid Advertisement Disclaimer & Disclosure: This content is not financial or investment advice, and the authors are not licensed brokers, dealers or advisors. This article was Published by the. Wall Street Wire™ platform and network, which is operated by Arx Advisory Ltd (the “Operators”). The Operators receive a monthly cash subscription fee from Nuvectis Pharma (NVCT) via bank transfer for services relating to promotional content and news distributions on various media and social channels. The Operators may received additional cash fees for monitoring, data or IR/advisory services on top of that. For specific details and full disclosures on the exact cash amounts paid for the Wall Street Wire subscription and the start date of such services, please refer to our full disclosure document: https://redditwire.com/terms Contact Details News Coverage media.globalmarkets@gmail.com

June 20, 2025 11:56 AM Eastern Daylight Time

With Fresh Funding and Strong Phase 3 Data, PolyPid Advances Towards FDA Approval

Global Markets News

PolyPid Ltd. (NASDAQ: PYPD) * announced Tuesday that it has secured $26.7 million through warrant exercises following its successful SHIELD II Phase 3 trial results. This funding milestone extends the company’s runway beyond the anticipated FDA approval of its breakthrough surgical infection prevention technology, D-PLEX₁₀₀. For savvy biotech investors seeking undervalued opportunities with near-term catalysts, PolyPid presents a compelling case study in market inefficiency and potential outsized returns. A David Taking On a $10 Billion Goliath Surgical site infections (SSIs) represent a massive burden on healthcare systems, costing hospitals tens of thousands of dollars per incident while significantly increasing patient mortality. The $10 billion SSI prevention market has long awaited innovation beyond traditional antibiotic approaches. Enter PolyPid’s proprietary PLEX (Polymer-Lipid Encapsulation matriX) platform, which delivers targeted antibiotics directly at surgical sites for a full 30 days—dramatically longer than conventional methods that typically provide only hours of protection. “D-PLEX₁₀₀ demonstrated a statistically significant reduction in surgical site infections and successfully met the study’s primary endpoint and all key secondary endpoints,” the company stated in its announcement of the Phase 3 SHIELD II trial results. Most impressively, in patients with large surgical incisions, earlier SHIELD I data showed a remarkable 54% reduction (p=0.0032) in the composite endpoint of infections, reinterventions, and mortality compared to standard of care alone. The more recent SHIELD II trial demonstrated an even more stunning 58% reduction in surgical site infections, dropping infection rates from 9.5% with standard care to just 3.8% when D-PLEX100 was added. Why This $36M Company Could Soon Command a Valuation in the Hundreds of Millions Despite delivering transformative clinical results, PolyPid currently trades around $3.53 per share (as of June 18, 2025), representing a market cap of approximately $36 million – a significant discount to comparable companies in the surgical and pain management sectors, many of which command valuations in the hundreds of millions to over $1 billion. This valuation disconnect creates a potential opportunity for investors ahead of multiple catalysts: 1. NDA Submission in Early 2026: The company expects to file its New Drug Application in early 2026, leveraging Fast Track and Breakthrough Therapy designations already granted by the FDA. 2. Medicare’s New Technology Add-On Payment Eligibility: D-PLEX₁₀₀ qualifies for this program, potentially providing up to 75% reimbursement during early commercialization years. 3. U.S. Partnership Discussions: Management noted during a recent call that there has been “a change in partnering interest following December’s interim analysis,” with large pharmaceutical and medical device companies representing logical partners. 4. Substantial Market Opportunity: With 12 million eligible surgeries annually in the U.S. alone and another 8 million in Europe, D-PLEX₁₀₀’s market potential is substantial. 5. European Partnership Already Secured: PolyPid has secured a European commercialization partnership with Advanz Pharma worth up to $115 million plus double-digit royalties. The newly secured $26.7 million adds to PolyPid’s existing capital resources. With this additional funding, the company has stated that its runway would be extended beyond anticipated FDA approval of D-PLEX₁₀₀. Beyond D-PLEX₁₀₀: Platform Technology Offers Additional Growth Potential While D-PLEX₁₀₀ drives immediate value creation, PolyPid’s broader PLEX platform provides significant growth opportunities beyond surgical infections. Their OncoPLEX program applies identical technology principles to deliver cancer therapeutics directly to tumor sites, potentially revolutionizing solid tumor treatment approaches. A recent collaboration with ImmunoGenesis validates the platform’s broader applications beyond surgical infections. According to recent analyst reports, Wall Street remains bullish on PolyPid. H.C. Wainwright recently raised their price target to $13 (from $11), while analysts from JMP Securities and Craig-Hallum have maintained Buy ratings. On June 5, 2025, Roth MKM initiated coverage with a Buy rating. The consensus among Wall Street professionals points to price targets ranging from $10-13, suggesting significant upside potential from current levels. The Bottom Line For investors seeking opportunities with clear catalysts, PolyPid represents a compelling combination of transformative clinical results, definitive regulatory pathway, and strong Wall Street support. With clinical risk substantially reduced following successful Phase 3 results and a regulatory submission timeline now established, the focus shifts to commercial execution and partnership value creation—potentially setting the stage for significant share price appreciation as these milestones materialize. The company’s notable discount to peers, extended cash runway, and multiple near-term value drivers make it an intriguing opportunity for biotech investors looking for undervalued assets with clear paths to value creation. Recent News Highlights from PolyPid PolyPid Secures $26.7 Million Through Warrant Exercise Following Successful SHIELD II Phase 3 Trial Results PolyPid Announces Positive Topline Results from Phase 3 SHIELD II Trial: D-PLEX₁₀₀ Demonstrated Significant Reduction in Surgical Site Infections and Successfully Met Primary and All Key Secondary Endpoints This article is syndicated from The Finance Herald. * Paid Advertisement Disclaimer & Disclosure: This article was Published by Wall Street Wire™. Wall Street Wire™ is owned and operated by Arx Advisory Ltd (the “Operator”). The Operator receives an ongoing monthly subscription fee of $5,000 cash via bank transfer (since May 1st, 2025 which is ongoing as of the date of publication) from PolyPid Ltd (PYPD) (IL0011326795) to produce and distribute this content and additional promotional content and news distributions on various media and social channels. The operator receives additional cash fees for non promotional data and consulting subscriptions from PolyPid. This content is not financial or investment advice, and the authors are not licensed brokers, dealers or advisors. Please refer to our full disclosure and disclaimer here: https://redditwire.com/terms. Contact Details Wall Street Wire media.globalmarkets@gmail.com

June 18, 2025 11:22 AM Eastern Daylight Time

CURE ALZHEIMER’S FUND PRESENTS THE JEFFREY L. MORBY PRIZE FOR EXCEPTIONAL RESEARCH

Alzheimer’s Disease Research Foundation

Cure Alzheimer’s Fund, a nonprofit dedicated to funding the most promising research to prevent, slow or reverse Alzheimer’s disease (AD), has announced the recipients of the second annual Jeffrey L. Morby Prize. Senior author Andrew S. Yoo, Ph.D., and first author Zhao Sun, Ph.D., both of Washington University School of Medicine in St. Louis, were selected by their peers for their paper “ Modeling late-onset Alzheimer’s disease neuropathology via direct neuronal reprogramming,” published in Science in August 2024. The Morby Prize is named in honor of the late Co-Founder of Cure Alzheimer’s Fund, Jeffrey L. Morby, who inspired the nonprofit’s mission 20 years ago to fund research as a path to ending Alzheimer’s disease. Mr. Morby passed away in September 2023. Established in 2024, the Morby Prize will be awarded annually to the senior and first authors of a recent scientific publication that transforms the fundamental understanding of Alzheimer’s disease and opens new paths to translate scientific results into effective ways to prevent, diagnose or treat the disease. This year’s award included $200,000 for the senior author’s lab for Alzheimer’s disease-related research. “Honoring researchers whose work is determined by their peers as breakthrough thinking and having meaningful impact on the Alzheimer’s community is a fitting tribute to Jeff’s remarkable legacy of empowering scientists to pursue rigorous and innovative research,” said Meg Smith, CEO of Cure Alzheimer’s Fund. “The many extraordinary CureAlz-funded projects that resulted in published papers in 2023 and 2024 made the competition for this award fierce, and the endorsement of this paper by their peers speaks to the importance of the work of Drs. Yoo and Sun and their co-authors.” The paper describes a groundbreaking method to study aged neurons in the lab without requiring a brain biopsy, enabling more accurate modeling of late-onset Alzheimer’s disease. By transforming skin cells from patients directly into neurons that reflect the aging process, scientists now can observe key disease features, such as amyloid beta plaque buildup, offering new insights into Alzheimer’s disease development and potential treatment approaches. “With the demonstration that direct neuronal reprogramming can model neuropathological features of late-onset Alzheimer’s disease, this method will enable us to dissect how aging, as the primary risk factor, contributes to neurodegeneration,” said Dr. Yoo. “Moreover, the generous support from the Jeffrey L. Morby Prize will further allow us to develop reprogramming approaches to generate different neuronal subtypes and investigate neuron-intrinsic aging mechanisms in the context of specific cell types. We are excited about the possibility of delineating the mechanisms by which different neuronal subtypes become vulnerable or resilient to AD with aging.” About The Yoo Lab Andrew S. Yoo, Ph.D., is a distinguished neuroscientist and professor in the Department of Developmental Biology at Washington University School of Medicine in St. Louis. His lab focuses on microRNAs as neurogenic genetic inputs and reprogramming effectors to generate human neurons by directly reprogramming non-neural somatic cells. Using this approach, his team investigates how aging in human neurons contributes to the adult- and late-onset of neurodegeneration employing neurons derived from individuals with various neurodegenerative disorders. About Cure Alzheimer's Fund Cure Alzheimer’s Fund is a nonprofit dedicated to funding the most promising research to prevent, slow or reverse Alzheimer’s disease. Since its founding in 2004, Cure Alzheimer’s Fund has provided 971 grants to more than 300 of the world’s leading researchers and contributed more than $232 million to research. Its funded initiatives have been responsible for many key breakthroughs in understanding the causes and pathology of Alzheimer’s disease. Cure Alzheimer’s Fund has achieved a 100% perfect score and a Four-Star rating for 13 consecutive years from Charity Navigator. Cure Alzheimer’s Fund also received a Platinum Seal of Transparency from Candid, formerly known as GuideStar. Our Board of Directors, Trustees and a core group of other donors direct their donations to our overhead expenses so that 100% of general donations go to our research program. For more information, visit CureAlz.org. Contact Details Barbara Chambers +1 978-417-9890 bchambers@curealz.org Company Website http://curealz.org

June 18, 2025 05:25 AM Eastern Daylight Time

BiomX Stock Could Soar 3000% As This $10M Biotech Cracks The 'Superbug' Code, Wall Street Says

Global Markets News

BiomX Inc. (NYSE: PHGE)* has achieved what Big Pharma couldn't accomplish in over 20 years — successful clinical trials using viruses to treat life-threatening infections that no longer respond to antibiotics. The $10 million biotech has reported positive Phase 2 results in diabetic foot bone infections, a condition so challenging that no new drugs have been approved for it in two decades. Meanwhile, their cystic fibrosis program showed 14% of patients completely cleared chronic lung infections after just 10 days of treatment. Approximately 160,000 lower limb amputations occur annually in diabetic patients in the U.S., with 85% caused by diabetic foot infections or diabetic foot osteomyelitis — creating an $8 billion annual healthcare burden according to company data. Current treatments rely on antibiotics that increasingly fail due to resistance, often leaving amputation as the only option. Clinical Breakthroughs Across Two Major Programs BiomX's March 2025 Phase 2 results in diabetic foot osteomyelitis from 41 patients delivered notable outcomes. The company achieved statistically significant percent area reduction of ulcer size, with p-values of 0.046 at week 12 and 0.052 at week 13. The treatment showed separation from placebo starting at week 7, with differences greater than 40% by week 10. BiomX also demonstrated statistically significant improvements in ulcer depth and reducing ulcer area expansion, while BX211 was safe and well-tolerated throughout the study. The company's cystic fibrosis program has been equally impressive. In their Phase 1b/2a study, 14.3% of patients converted to sputum culture negative for P. aeruginosa after 10 days of treatment, compared to 0% in the placebo group. One patient had been infected for 35 years before achieving complete clearance. The FDA has granted this program both Fast Track designation and Orphan Drug Designation, potentially accelerating the approval pathway. BiomX's approach uses bacteriophages — viruses that naturally target and kill specific bacteria — instead of traditional antibiotics that bacteria can develop resistance against. The company has overseen more than 50 compassionate use cases with no significant side effects to date. Military Validation and Wall Street's Bullish Take The U.S. Defense Health Agency has provided $40 million in non-dilutive funding to BiomX's diabetic foot program, representing significant validation of the technology. "They're seeing soldiers coming out of the Ukraine war with extremely antibiotic-resistant infections," CEO Jonathan Solomon said during the company's May 2025 earnings call. Despite the clinical progress and military backing, BiomX trades at approximately $10 million market cap — a disconnect0 that has caught Wall Street's attention. H.C. Wainwright maintains a Buy rating with a $15 price target, representing potential upside of over 3000% from recent levels around $0.4 Laidlaw & Company rates the stock Buy with a $16 price target, suggesting almost 4000% upside potential. Laidlaw analyst Yale Jen called the recent data "an absolutely positive surprise" and characterized BX211 as "a high value and clinically de-risked asset." The analysts' optimism stems from the clinical validation across both programs, massive addressable markets, and limited competition in the phage therapy space. Major Catalysts on the Horizon BiomX estimates addressable markets exceeding $2.5 billion globally for their diabetic foot program and $1.6 billion for cystic fibrosis based on patient populations and potential pricing benchmarks. The company expects to have sufficient funding through Q1 2026, aligning with anticipated BX004 Phase 2b results in cystic fibrosis. Key upcoming catalysts include the Phase 2b readout for their cystic fibrosis program expected in Q1 2026, ongoing Phase 2/3 trial discussions with the FDA for their diabetic foot program, and potential regulatory meetings in the second half of 2025. The company is also exploring partnership opportunities as the phage therapy space attracts increasing attention from large pharmaceutical companies. With validated clinical data, military funding, and Wall Street price targets suggesting potential returns exceeding 3000%, BiomX could offer investors exposure to phage therapy as a potential new approach to treating antibiotic-resistant infections. As the global antibiotic resistance crisis intensifies, the company's nature-based approach to killing bacteria positions it at an interesting inflection point in infectious disease treatment. BiomX shares were trading at ~$0.4 at last check Recent News Highlights from BiomX BiomX Reports First Quarter 2025 Financial Results and Provides Business and Program Updates BiomX Announces Positive Topline Results from Phase 2 Trial Evaluating BX211 for the Treatment of Diabetic Foot Osteomyelitis (DFO) * Legal Disclaimer & Disclosure: Nothing in this report constitutes financial or investment advice, nor does it represent an offer to buy or sell securities. This report is published by Wall Street Wire™. The operators of Wall Street Wire, arx advisory, are not registered brokers, dealers, or investment advisers. This report contains and is a form of paid promotional content or advertisement for BiomX Inc and was produced as part of their paid subscription to Wall Street Wire. This report has not been reviewed or approved by BiomX Inc prior to publication. The operators of wall street wire have received or are expected to receive a monthly recurring fee of five thousand united states dollars via wire transfer from BiomX as part of an ongoing agreement starting June 1st, 2025 in return for social media distribution and promotional coverage services, and receive additional compensation for non promotional unrelated data and advisory services on top of that. They do not hold any shares in BiomX. Please review the full disclaimers and compensation disclosures here for further details: redditwire.com/terms. We are not responsible for the price targets mentioned in this article nor do we endorse them, they are quoted based on publicly available news reports believed to be reliable and additional or price targets may exist that may not have been quoted. Readers are advised to refer to the full reports mentioned on various systems and the disclaimers/disclosures they may be subject to. Contact Details News Coverage ronald@futuremarketsresearch.com

June 16, 2025 07:04 PM Eastern Daylight Time

Sheon Karol Joins West Lane Partners as Senior Advisor

West Lane Partners

West Lane Partners, a private equity firm focused on special situations in middle market companies spanning healthcare, tech, financial services and industrials, is pleased to announce that Sheon Karol, a nationally recognized investment banker and restructuring advisor, has joined the firm as a Senior Advisor. Mr. Karol brings over three decades of experience in investment banking, restructuring, and senior corporate leadership, with deep expertise in complex M&A, capital raises, and operational turnarounds. Skilled in de-risking situations, he brings a flexible yet disciplined approach that favors iterative decision-making over rigid or binary choices. His ability to surface a range of strategic options, often under pressure, has made him a trusted advisor to owners navigating both opportunity and uncertainty. His contributions to the field have earned national recognition, including the “Boutique Investment Banker of the Year” award from the Atlas Awards. “Sheon and I have been in the trenches together on complex deals. He’s masterful at aligning stakeholders, cutting through noise, and adapting in real time to keep transactions on course. Where others see roadblocks, he sees possibility—and responds with clarity and flexibility,” said Deryck Palmer, Founder and Managing Partner at West Lane Partners. “His dynamic approach, experience, and deep market insight into the industries on which we’re focused, and an instinct for what owners value most, makes him an exceptional addition to our firm.” “I think of the middle market as the river less fished” said Mr. Karol. “Middle market companies are often overlooked, undercapitalized, and underserved by institutional talent. At West Lane Partners, our focus on investments between $25 million and $75 million is about more than deal size—it’s about bringing high-caliber insight to businesses at pivotal moments and tailoring strategic options to match the evolving goals of owners and the realities of the market. The result is not just getting deals done, but generating long-term value others might miss.” Mr. Palmer added, “I’ve always been impressed by Sheon’s expertise, creativity, positivity and determination to get the best for his clients. These qualities enable him to inexorably bring difficult situations to their best possible conclusion and there are few who bring such capabilities to the middle market.” About Sheon Karol Mr. Karol has advised on high-stakes transactions across a myriad of industries in the middle market, including manufacturing, biotech, pharma, for-profit education, medical research, agriculture, consumer goods, food & grocery, sports, and technology. Mr. Karol has successfully executed a wide range of strategic transactions, including M&A advisory, capital raises, and restructurings, for both healthy and distressed businesses and their stakeholders. He has also served in executive capacities, including as Chief Restructuring Officer of a $1 billion company, for which he renegotiated the company's debt and avoided a bankruptcy filing. Many of Mr. Karol’s transactions, including Violin Memory and Peekay Boutiques, have won awards. He served as SVP of Winn-Dixie and managed the company's sale of assets in excess of $200 million and the disposition of 326 stores (in a 90-day period); guided the auction and sale of Farmland’s nitrogen fertilizer business that exceeded the “stalking horse” bid by $25 million; advised the CRO in the sale of the Texas Rangers baseball team; and advised foreign buyers in their U.S. expansion. Trustee positions include the Violin Memory and Lily Robotics Trusts. A middle market M&A thought leader, he writes and lectures widely, including on entrepreneurship, auction theory, sale processes, the middle market and foreign buyers. He holds FINRA SIE, Series 63 and Series 79 certifications. Mr. Karol received a J.D. from Yale Law School and a B.A. from Yeshiva College. About West Lane Partners West Lane Partners is a private equity firm whose senior leadership has over 150 years of collective restructuring and private equity experience working with underperforming, stressed and distressed companies across a range of industries in both large cap and middle market companies. In addition to providing capital, the firm combines decades of restructuring, private equity, legal and financial expertise to collaborate with management in developing and executing bespoke solutions that deliver mutually beneficial outcomes. Contact Details Curtis Johnson, Investor Relations +1 973-404-0999 cjohnson@westlanepartners.com Meir Kahtan Public Relations, LLC Meir Kahtan +1 917-864-0800 mkahtan@rcn.com Company Website https://www.westlanepartners.com

June 11, 2025 10:00 AM Eastern Daylight Time

CURE ALZHEIMER’S FUND APPOINTS TWO NEW MEMBERS TO ITS BOARD OF DIRECTORS

Alzheimer’s Disease Research Foundation

Cure Alzheimer’s Fund, a nonprofit dedicated to advancing research with the highest potential to prevent, slow or reverse Alzheimer’s disease, announced today that Christine Villas-Boas and Brittany Bowlen have been appointed to its Board of Directors. “We are pleased to welcome two new voices to our Board—Christine and Brittany each bring a unique passion and perspective that will help us better serve our mission to fund research aimed at curing Alzheimer’s disease,” said Henry McCance, Board Chair and Co-Founder of Cure Alzheimer’s Fund. “This expansion of our board is a meaningful step forward as we continue to grow thoughtfully and stay focused on making a lasting impact on the fight against this devastating disease.” “Brittany and Christine bring outstanding leadership expertise and a clear passion for our cause,” said Meg Smith, CEO of Cure Alzheimer’s Fund. “Their diverse experience in strategy and commitment to impactful philanthropy will enhance our efforts to accelerate critical research. We’re excited to welcome their insight and energy to our board.” Christine Villas-Boas currently serves as President and Treasurer of the Michel and Claire Gudefin Family Foundation, a leading supporter of Cure Alzheimer’s Fund. Ms. Villas-Boas, a Connecticut College graduate, began her career at Chase Manhattan Bank in 1974, working in U.S. Corporate Banking and International Capital Markets across New York, Paris, and London. She later consulted in credit and corporate finance training. Ms. Villas-Boas also serves on the board of the Learn2Earn Charitable Foundation based in Naples, Florida. Inspired by personal loss—her mother Claire, who died of Alzheimer’s in 2015, and other family members affected by the disease—Christine and the Michel and Claire Gudefin Family Foundation are deeply committed to supporting Cure Alzheimer’s Fund in its mission to find a cure. She became a Trustee in 2021 and joined the Board of Directors in 2025. Brittany Bowlen is a seasoned leader in consulting and professional sports, most recently serving as the Senior Vice President of Strategy for the Denver Broncos. In addition to her professional career, Brittany is deeply committed to driving community impact, currently serving as the Vice Chair of the Board of Directors for Boys & Girls Clubs of Metro Denver and as a member of the Board of Visitors for Duke University’s Fuqua School of Business. She holds a Master of Business Administration (MBA) from Fuqua and a Bachelor of Business Administration (BBA) from the University of Notre Dame’s Mendoza College of Business. Cure Alzheimer’s Fund is a nonprofit dedicated to funding the most promising research to prevent, slow or reverse Alzheimer’s disease. Since its founding in 2004, Cure Alzheimer’s Fund has provided 971 grants to more than 300 of the world’s leading researchers and contributed more than $232 million to research. Its funded initiatives have been responsible for many key breakthroughs in understanding the causes and pathology of Alzheimer’s disease. Cure Alzheimer’s Fund has achieved a 100% perfect score and a Four-Star rating for 13 consecutive years from Charity Navigator. Cure Alzheimer’s Fund also received a Platinum Seal of Transparency from Candid, formerly known as GuideStar. Our Board of Directors, Trustees and a core group of other donors direct their donations to our overhead expenses so that 100% of general donations go to our research program. For more information, visit CureAlz.org. Contact Details Barbara Chambers +1 978-417-9890 bchambers@curealz.org Company Website http://curealz.org

June 03, 2025 08:41 AM Eastern Daylight Time

Inspira Technologies Receives $2 Price Target and Buy Rating: Everything You Need to Know

Global Markets News

Litchfield Hills Research has initiated coverage of Inspira Technologies OXY B.H.N. Ltd. (NASDAQ: IINN)* with a Buy rating and a $2 price target, representing potential upside of over 225% from current trading levels of around $0.61 per share. This bullish outlook comes as the medical technology company continues to critical care technology addressing what the analyst describes as "a medical need without good options." The analyst notes that mechanical ventilators are "WWII technology in desperate need of an upgrade" with reports showing that 30% to 50% of ICU patients don't survive. Unlike mechanical ventilation, Inspira's ART500 technology would enable patients to remain awake during treatment while stabilizing oxygen levels without intubation and coma. What distinguishes Inspira from typical early-stage medical device companies is its proven regulatory execution and early commercial success. The company's first generation technology, the INSPIRA ART100 system, received FDA clearance in May 2024 and is already deployed in leading U.S. hospitals. The excitement around this technology reached a new high in April 2025 when the first successful patient treatment was completed at Westchester Medical Center. The commercial momentum seems to be accelerating. Inspira announced it received payment in the "low hundreds of thousands of dollars" from its U.S. distributor for delivered systems, marking the company's first revenues. CEO Dagi Ben-Noon called this "a transformative milestone for Inspira as we establish our presence in the U.S. medical landscape." The company has now initiated global commercial rollout discussions and expects additional deliveries in the second half of 2025. Central to Inspira's technology platform is the AI-powered HYLA blood sensor, which recently achieved 96% accuracy in clinical studies at Sheba Medical Center, one of the world's top hospitals. The system provides continuous monitoring without requiring blood draws, targeting the blood gas analyzer market projected to reach $5.7 billion by 2030. The analyst identifies massive market opportunities, with the global mechanical ventilators market expected to reach $20.69 billion by 2034. Inspira's flagship INSPIRA ART500 system in development aims to disrupt this market by providing respiratory support through direct blood oxygenation rather than forcing air into damaged lungs. Inspira has established strong intellectual property protection with multiple U.S. patents and novel patent claims protecting its core technologies. The company is executing a strategic approach of securing FDA clearance for individual components before integrating them into comprehensive systems. When comparing Inspira to similar medical device companies, the analyst found the stock trades at significant discounts despite having FDA-cleared technology already treating patients. The $2 price target reflects confidence in the company's ability to capitalize on its early commercial success and expand into the massive mechanical ventilation market. The analyst concludes that Inspira may represents a unique opportunity, combining proven FDA-cleared technology with substantial market opportunity and attractive valuation metrics in the high-growth medical device sector. Recent News from Inspira: Inspira Technologies Initiates Global Commercial Rollout of FDA-Cleared ART100 System INSPIRA ART100 System Approved by Israel's Largest Healthcare Provider for Use in Organ Transplant Patients Inspira Achieves above 99% Gas Exchange Efficiency in VORTX™ Technology In-Vivo Animal Testing * Legal Disclaimer & Disclosure: Nothing in this article constitutes financial or investment advice, nor does it represent an offer to buy or sell securities. This report is published by the Wall Street Wire platform & media network. The operators of Wall Street Wire are not registered brokers, dealers, or investment advisers. This article contains paid promotional content related to Inspira Technologies and was produced as part of their paid subscription to Wall Street Wire, which includes a monthly fee of five thousand US dollars paid in cash via bank transfer in return for promotional content and distribution services. The operators also receive additional fees for non promotional advisory and data services. Inspira Technologies did not necessarily review or approve this content prior to publication. Please review the full disclaimers and compensation disclosures here which include further details: redditwire.com/terms. We are not responsible for third party analyst price targets or market estimates are refer to them based on publicly availble reports. Additional or competing price target may exist and readers are advised to refer to the full report and its respective disclaimers and disclosures. Contact Details Wall Street Wire Editorial Desk media.globalmarkets@gmail.com

June 02, 2025 09:19 AM Eastern Daylight Time

Centre for Neuro Skills Chief Financial Officer Named 2025 Kern County Heart Walk Chair

Centre for Neuro Skills

Lindsay Ashley, chief financial officer of Centre for Neuro Skills, has been named chair of the American Heart Association ’s 2025 Kern County Heart and Stroke Walk. The annual event is scheduled for Saturday, Oct. 11, at California State University, Bakersfield. “The Kern County Heart and Stroke Walk is an opportunity to celebrate heart disease and stroke survivors, raise lifesaving funds for the American Heart Association and encourage a healthy lifestyle,” said Ashley. “By bringing the community together to raise awareness and funds to fight heart disease and stroke, we’re making strides to ensure our loved ones can live longer, healthier lives.” Ashley will lead a team of Kern County-area executives to recruit companies and organizations to take part in the Heart and Stroke Walk. The leadership team and supporting organizations will raise funds for the American Heart Association while leading action-oriented conversations about employee health, corporate engagement, community health and community transformation. The American Heart Association is the world’s leading non-profit dedicated to a world of healthier lives for all. In addition to Ashley, the 2025 Kern County Heart and Stroke Walk executive leadership team includes: David Harrington, Centre for Neuro Skills Didra Cantu, MPA-HCM, Encompass Health Rehabilitation Hospital George Jenkins, Dignity Health, Bakersfield Memorial Hospital Ken Keller, Dignity Health, Bakersfield Memorial Hospital Kevin Burton, Klein DeNatale Goldner Lindsay Barnes, KGET-TV 17 Lisa Kreber, PhD, CBIS, Adventist Health Bakersfield Scott Salters, Cushman & Wakefield | Pacific Commercial Realty Advisors Sky Newton, SHRM-CP, Valley Strong Credit Union "The Heart and Stroke Walk is a fantastic chance for Kern County to come together as a united community, standing strong against heart disease and stroke," said Kelley Berry, executive director of the American Heart Association, Kern County. "We are immensely grateful for Lindsay's steadfast expertise, passion, and dedication to our mission. Leaders like her are crucial in our ongoing efforts to save lives and provide hope to families affected by heart disease and stroke." Funds raised go toward the American Heart Association’s work to advance lifesaving research, education and health for everyone. In Kern County, the Association has expanded access to CPR skills, connected local heart and stroke patients to the latest science-based treatments through its hospital programs and supported community members managing high blood pressure with tools and resources for better blood pressure control. Heart disease and stroke are largely preventable and how you eat, move and manage stress impacts your well-being, physically and mentally. Participants in the Heart and Stroke Walk gain access to resources, tools and activities to support both mental and physical well-being for employers and employees. Participants can register for the event at BakersfieldHeartWalk.com. Registrants can also create personal fundraising pages, download the Heart Walk mobile app and encourage family and friends to join. Companies interested in participating can contact Kelley Berry at Kelley.berry@heart.org. Centre for Neuro Skills, with seven locations across California and Texas, will be participating in American Heart Association’s local heart walk events across both states. Dr. Matt Ashley, Chief Medical Officer of Centre for Neuro Skills, currently serves as Board President on the Central Texas American Heart Association’s Board of Directors and will transition to Board Chair this July. As a former Heart Walk Chair in Austin, Texas, Dr. Matt Ashley remains committed to participating in and supporting the Central Texas Heart Walks. *** About the American Heart Association The American Heart Association is a relentless force for a world of longer, healthier lives. Dedicated to ensuring equitable health in all communities, the organization has been a leading source of health information for more than one hundred years. Supported by more than 35 million volunteers globally, we fund groundbreaking research, advocate for the public’s health, and provide critical resources to save and improve lives affected by cardiovascular disease and stroke. By driving breakthroughs and implementing proven solutions in science, policy, and care, we work tirelessly to advance health and transform lives every day. Connect with the American Heart Association in Kern County on heart.org/southern-california, Facebook, Instagram, X or by calling 1-800-AHA-USA1. About Centre for Neuro Skills Centre for Neuro Skills is an experienced and respected world leader in providing intensive rehabilitation and medical programs for those recovering from all types of brain injury. CNS covers a full spectrum of advanced care from residential and assisted living to outpatient/day treatment. Founded by Dr. Mark Ashley in 1980, CNS has seven locations in California and Texas. For more information about Centre for Neuro Skills, visit neuroskills.com, Facebook, Twitter, LinkedIn, YouTube. For a video overview of CNS, visit our YouTube channel. Media, please note: Visual assets, including photos, are available. To request an interview with CNS leadership or clinical staff, please contact Robin Carr at 415.766.0927 or CNS@landispr.com. ### Contact Details Landis Communications Inc. Andie Davis +1 415-766-8355 cns@landispr.com Company Website https://www.neuroskills.com/

May 20, 2025 08:01 AM Pacific Daylight Time

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Market Alert: DarioHealth Receives $3 Price Target and Buy Rating: Everything You Need to Know

Global Markets News

Litchfield Hills Research has initiated coverage of DarioHealth Corp. (NASDAQ: DRIO)* with a Buy rating and a $3 price target, representing potential upside of over 350% from current trading levels of around $0.66 per share. This bullish outlook comes as the digital health company continues to transform its business model and expand its comprehensive chronic care platform. DarioHealth has successfully pivoted from a direct-to-consumer model to a B2B2C (business-to-business-to-consumer) approach since 2020. This strategic shift has allowed the company to leverage its consumer platform strengths while expanding sales to health plans and employers. The company's B2B2C recurring revenue grew by an impressive 398% year-over-year in Q4 2024, demonstrating strong market adoption. The analyst highlights Dario's proven track record of both organic growth and strategic acquisitions, including the recent Twill acquisition which has strengthened its multi-condition platform. This expansion has positioned Dario to address five of the most common, expensive chronic conditions through a single, integrated solution. The $3 price target is based on a discounted future earnings model with a 9% discount rate. The analysis assumes Dario will reach GAAP breakeven in the second half of 2026, continue strong revenue growth to reach $66.1 million in 2026, achieve non-GAAP operating income of $17.4 million in 2026, and show improving gross margins, exceeding 80% in its core B2B2C business. Importantly, the report demonstrates that even at the $3 target price, Dario would trade at approximately 2.2x projected 2026 sales, which is still below the peer average of 2.28x. The analyst suggests Dario should command a premium multiple given its high growth profile and comprehensive platform. The report highlights Dario's unique competitive advantages relative to peers in the digital health space. Unlike competitors who focus on single conditions, Dario offers a comprehensive platform addressing diabetes, hypertension, weight management, musculoskeletal pain, and behavioral health. When comparing current market cap to sales and enterprise value to sales multiples, Dario trades at substantial discounts – 81% below peers on market cap to sales ratio and 54% below peers on enterprise value to sales ratio. This valuation gap, combined with Dario's proven clinical outcomes and expanding market presence, forms the core of the analyst's bull case. A significant growth driver highlighted in the report is Dario's expansion into the GLP-1 weight management space. The company's research has shown that members using GLP-1 experienced significant reductions in blood glucose levels in the first five months with changes sustained throughout the year. With the GLP-1 market projected to reach $100 billion by 2030, Dario's comprehensive solution combining medication management with behavioral support positions it to capture market share in this rapidly growing segment. Strategic partnerships, including its recent collaboration with Rula Health, further strengthen Dario's offering by providing access to over 15,000 behavioral health providers nationwide. The company is also leveraging AI technology to reduce operating expenses, with projections suggesting a 20% reduction in expenses between Q4 2024 and Q4 2025 through AI-driven process optimization. Litchfield Hills projects Dario's revenue will grow to $35.9 million in 2025 and $66.1 million in 2026, with gross margins improving to nearly 70% by 2026. The company is expected to achieve operational cash flow breakeven by late 2025, with full profitability in the second half of 2026. The recent $25.6 million private placement has strengthened Dario's balance sheet, providing sufficient runway to execute its strategic plan. With a blue-chip client list that includes major employers like Amazon, Microsoft, and Google, as well as top insurers and pharmaceutical companies, Dario appears well-positioned to capitalize on the growing demand for integrated digital health solutions that deliver measurable clinical outcomes and positive ROI. Recent News from Dario: DarioHealth Reports First Quarter 2025 Financial and Operating Results Dario's Digital Health Solution Demonstrates Effectiveness in New Research Examining Flu Vaccination Awareness in High-Risk Populations DarioHealth Closes Strategic Refinancing of Existing Debt Facility of up to $50 Million to Provide Additional Operational Flexibility and Support Growth Initiatives * Legal Disclaimer & Disclosure: Nothing in this article constitutes financial or investment advice, nor does it represent an offer to buy or sell securities. This report is published by the Wall Street Wire platform & media network. The operators of Wall Street Wire are not registered brokers, dealers, or investment advisers. This article contains paid promotional content related to DarioHealth and was produced as part of their paid subscription to Wall Street Wire, which includes a monthly fee of five thousand US dollars paid in cash in return for promotional content and distribution services. The operators also receive additional fees for non promotional advisory and data services. DarioHealth did not necessarily review or approve this content prior to publication. Please review the full disclaimers and compensation disclosures here: redditwire.com/terms. We are not responsible for third party analyst price targets are refer to them based on publicly availble reports. Additional or competing price target may exist and readers are advised to refer to the full report and its respective disclaimers and disclosures. Contact Details Wall Street Wire Network media.globalmarkets@gmail.com

May 19, 2025 07:51 AM Eastern Daylight Time

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