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Obesity And Back Pain: BioRestorative Therapies Inc. Is Working To Address 2 Common Ailments That Plague Americans with a Major Near Term Data Catalyst

BioRestorative Therapies, Inc.

In 2016, Americans spent roughly $380 billion on lower back and neck pain. In the same year, medical costs for adult obesity in the United States were $260.6 billion. That’s why BioRestorative Therapies Inc. (NASDAQ: BRTX) is working to develop treatments for these 2 indications, laser-focusing on obesity and lower back pain. Lower back pain and obesity are major health crises. Lower back pain is the leading cause of disability worldwide, and obesity has been identified as a national security threat by the Department of Defense. With the escalation of both lower back pain and obesity in recent years, companies have realized the market potential for finding ways to improve the lives of those suffering from these conditions. Companies such as Pfizer Inc. (NYSE: PFE), Novo Nordisk (NYSE: NVO) and Vertex Inc.. (NASDAQ: VRTX) seem to have recognized the market potential for potential obesity treatments and are actively looking for the next breakthrough in obesity therapies. FDA Authorizes BioRestorative to Begin Phase 2 Clinical Trials For Chronic Lower Back Pain Indication; Development For Brown Fat Indication Underway BioRestorative Therapies is looking into the viability of BRTX-100 as an alternative to current treatments for chronic lower back pain that manages the pain rather than attacking the root cause such as pain relievers, steroid injections and opioids. The Food and Drug Administration (FDA) has authorized BioRestorative to begin a Phase 2 clinical trial using BRTX-100 to treat persistent lower back pain resulting from pain-causing degenerative discs. Currently, BioRestorative Therapies is actively recruiting patients to participate in the Phase 2 study. More information can be found here https://clinicaltrials.gov/ct2/show/NCT04042844?term=brtx&draw=2&rank=1. Another treatment BioRestorative is developing is ThermoStem, which targets obesity and metabolic disorders through the use of brown adipose-derived stem cells to generate new brown fat tissue. This brown fat tissue has been shown to increase metabolic activity and potentially regulate metabolic dysfunction in mice. New Developments Might Promise Better Health BioRestorative Therapies’ leadership is excited about the company’s ability to continue developing its two major technologies that could potentially provide access to multibillion-dollar markets. The company raised $23 million last November 2021 and is funded to prosecute its phase 2 clinical trial targeting chronic lumbar disc disease. Major Catalyst Near Term BioRestorative plans to unveil major safety data for its new therapies within the first quarter of 2023. Company leadership believes this will be a major catalyst for driving growth because positive safety data would provide acceleration to enrollment in and provide major validation for BRTX-100’s Phase 2 clinical trial for lower back pain. BioRestorative also reports that top key opinion leaders (KOLS) are highly engaged in the company’s research and development and are having their clinical sites participate in BioRestorative’s clinical trial. The Company also reports they are oversubscribed in terms of high-quality clinical site selection. With the company’s recent developments, upcoming safety data reveals and involvement of KOLS, BioRestorative is confident that it is heading in a positive direction and is hopeful it will positively impact the lives of millions. BioRestorative Therapies was founded by scientists and researchers committed to developing stem cell therapies to address unmet needs in patients with highly prevalent conditions.Our advances in stem cell biology and delivery protocols harbor great promise in conditioning our bodies’ own regenerative potential to treat major diseases more effectively than current interventions.Today, BioRestorative is actively developing programs that aim to dramatically increase quality of care for both (i) chronic back pain caused by disc degeneration, as well as (ii) metabolic disorders including obesity and diabetes. This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Investor Relations ir@biorestorative.com Company Website https://www.biorestorative.com/

September 01, 2022 09:00 AM Eastern Daylight Time

Simple tips and tricks to tackle inflation and manage budgets this Back-To-School shopping season

YourUpdateTV

A recent poll from Morning Consult found that only 36% of parents can afford back-to-school shopping this year without any issues. The National Retail Federation’s latest back-to-school shopping survey also shows a third of families plan to cut back on other spending areas — in order to cover the cost of must-haves for the new school year. Even with so many people concerned about costs, back-to-school spending is expected to hit an all time high this year — a whopping $864 per household for K-12, and $1200 for college students. Despite all of these challenges, there are some simple tips and tricks to save every penny you can for back-to-school shopping and beyond: Look for Student and Seasonal Discount: Flash your student ID and many popular stores will give you discounted rates. You can also take advantage of student discounts through sites such as Unidays and Student Beans. College students usually get the most discounts but many stores have savings for grades K-12 too. Spread Out Payments Over Time with Reliable Buy Now, Pay Later Options: With rising costs, many consumers are looking for greater payment flexibility when making back-to-school purchases. Pay Later with PayPal lets you spread payments out over time. For purchases between $30-$1,500, you can select Pay in 4 1 and break the cost into four interest-free payments with the first payment due at time of purchase. For those larger back-to-school purchases, you can select the new Pay Monthly 2 option and break the total cost into monthly payments over a longer period of time. Pay Later with PayPal gives you more choice in how you pay for purchases so you can select the option that works best for your budget. Learn more at paypal.com/buynowpaylater. Use browser extensions for coupons and cash back: You might think you’ve found the best deal out there, but there’s a good chance there are even better prices still waiting to be discovered. The Easiest way to make sure you’re paying the lowest prices — is to Install the PayPal Honey 1 desktop “browser” extension. This online shopping tool automatically discovers coupons at your favorite stores— and applies the best ones it finds at checkout. It even helps you layer savings by finding rewards that you can redeem for cash back. You can find it at: www.joinhoney.com Shop Refurbished: There are plenty of apps and sites out there to help you track down any used or refurbished items on your list. Whether you’re shopping for textbooks, electronics or clothing, you’ll pay less than if you were to buy the item brand new. Plus, you can usually find discounted items in “like new” condition on many platforms for free.. Contact Details Your Update TV +1 212-736-2727 yourupdatetv@gmail.com

August 31, 2022 02:20 PM Eastern Daylight Time

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AMERICA DOMANI LAUNCHES “LA FAMIGLIA” SERIES BY IL PROGRESSO

America Domani

America Domani today announced the launch of its “La Famiglia” series by Il Progresso, an exclusive video and social media series celebrating Italian American owned businesses. Each campaign tells the story of a different Italian American owned business, showcasing each business’ journey, history and connection to their Italian heritage. “Perhaps nothing captures the essence of the American Dream for Italians more than entrepreneurship and business ownership,” said Al DiGuido, Publisher & CEO of America Domani. “Through our ‘La Famiglia’ series, we are proud to tell the story of the millions of Italian business owners who have contributed to American culture over the past centuries through their innovation, creativity and craftsmanship.” The “La Famiglia” series is produced under the Il Progresso title, which is wholly owned by America Domani. Il Progresso was founded in 1880 and for generations of Italian Americans, served as the most trusted and highly circulated daily newspaper, engaging millions of readers and leading advertisers from across the world. The Il Progresso section is now integrated within America Domani as a special section featuring historical content, vintage footage, interviews and interactive media that chronicles the Italian American journey over the past centuries. America Domani is the leading digital media community for everyone who has an affinity for Italian culture. To sign-up for notifications, visit www.americadomani.com. To inquire about having your business featured on America Domani’s “La Famiglia” series by Il Progresso, visit www.americadomani.com/lafamiglia ABOUT AMERICA DOMANI: America Domani is the leading digital media community for the 17 million Americans of Italian heritage and millions more who have a love and affinity for Italian culture. Staying true to the “Domani” name, which means “Tomorrow” in Italian, America Domani showcases a wide array of engaging content from top Italian American journalists, influencers and personalities, including news, food and wine, culture, travel, comedy, success stories, entertainment and more. America Domani was created through purchasing the licensing rights to the historic America Oggi newspaper and the revival of Il Progresso Italo-Americano. Both titles live proudly on the America Domani platform as dedicated sections for current events and historical content chronicling the Italian American journey over the past centuries. Contact Details Media press@AmericaDomani.com Company Website https://americadomani.com/

August 30, 2022 11:50 AM Eastern Daylight Time

Partnership for Food Safety Education Promotes “Don’t Wash Your Chicken”

Partnership for Food Safety Education

Salmonella causes more foodborne illnesses than any other bacteria.* To celebrate National Food Safety Education Month in September, the non-profit Partnership for Food Safety Education (PFSE), in collaboration with Drexel University and New Mexico State University, has launched “ Don’t Wash Your Chicken,” an educational program aimed at households preparing and cooking raw chicken at home. Informed by research from Drexel University, this program explains why certain poultry handling practices at home are risky and provides practical guidance people can take to reduce their risk of food poisoning. “This year marks the 25th anniversary of collective efforts to advance safe food handling messages, including safe poultry handling,” said Britanny Saunier, PFSE executive director. “This program addresses why people still wash their chicken and helps them understand why they don’t need to wash raw poultry. It is our hope that, collectively, we’re able to break through those barriers and influence real behavior change that reduces the rate of foodborne illnesses through these new tools.” This program features four animated videos to help home cooks stay healthy while preparing and cooking raw chicken. Aimed to reach a younger audience, the videos provide surprising, catchy food safety messages to grab the audience’s attention. Recent research found that home cooks continue to wash raw poultry because they desire to control the process of preparing food, lack of trust in chicken processing, and the habitual nature of the behavior. Research also revealed that home cooks are willing to change their behavior if they understand the “why” behind the guidance. This program aims to help households understand how chicken is processed before they get it, learn the risks of washing raw poultry, as well as how to safely handle and cook poultry at home. Along with the videos, this program highlights three key safe poultry handling messages: Washing or rinsing chicken increases risk. Salmonella, Campylobacter, and other harmful bacteria live on raw chicken. Washing or rinsing doesn’t remove this: worse, it helps the bacteria spread. When you add water through washing or rinsing, you give these bacteria a way to travel throughout your kitchen. Chicken has already been washed. Today’s manufacturing cleans the chicken, so there is no filth, feathers, or anything else on it that needs to be washed off. Poultry may have a coating of water and protein: this gets cooked off, or you can remove it with a clean paper towel. There’s a better, safer way to cook chicken. If you see anything on the chicken you want to get rid of, wipe it off with a clean paper towel. Separate raw chicken from fresh and ready-to-eat foods. Keep surfaces clean by washing them with hot, soapy water. Cooking chicken to 165°F using a food thermometer will kill any dangerous bacteria and make it safe to eat. For more campaign information and resources, visit the PFSE website at fightbac.org/poultry. * According to the Centers for Disease Control and Prevention About the Partnership for Food Safety Education The non-profit Partnership for Food Safety Education is the creator and steward of the popular Fight BAC!® national food safety education campaign and the national leader in disseminating information around the linkage of food safety consumer education with positive health outcomes. Food safety and health educators, and consumers, can download free food safety education information from the Partnership’s website at www.fightbac.org. Contact Details Shawnté R. Loeri +1 804-677-2971 sloeri@fightbac.org

August 30, 2022 09:00 AM Eastern Daylight Time

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Federated Indians of Graton Rancheria Announce $3.5M Donation to Complete Construction of the New Library in Roseland

Federated Indians of Graton Rancheria

The Federated Indians of Graton Rancheria (FIGR or Graton Rancheria) has donated $3.5 million to the Sonoma County Public Library Foundation for the construction of a new library in Roseland, located in Southwest Santa Rosa. Along with $16 million provided by the City of Santa Rosa and the State, in addition to $5M pending from other sources, this donation from Graton Rancheria helps close the construction gap of a total estimated project cost of $24.5 million. “We are so proud and happy to be able to support a full-service library in Roseland where so many of us grew up,” said Federated Indians of Graton Rancheria Tribal Chairman Greg Sarris. “Roseland is a community we love and support.” Developed in partnership with the City of Santa Rosa, the new Roseland Regional Library is part of an innovative Hearn Avenue Community Hub being built on a 6.5-acre site at the intersection of Hearn and Dutton Avenues. The 20,000-square-foot library will be part of a campus that will include a community center, an aquatic center and a new fire station. “The Federated Indians of Graton Rancheria’s leadership role in this capital campaign is a perfect fit with city, state and library funds that have already been committed to a new library in the Roseland/Southwest area of Santa Rosa,” said Deborah Doyle, Chair, Sonoma County Library Commission (SCL). “With those commitments and this generous gift, our construction goal is within reach, now we can focus on the $3 million left to raise to furnish and equip the 21st Century library that this community wants, needs and deserves. What a fabulous investment!” “We are so grateful for the generosity of the Federated Indians of Graton Rancheria,” said Mayor of Santa Rosa Chris Rogers. “Their support and partnership help put shovels in the ground as we deliver this critical project for the Roseland community.” “This extraordinary investment is a testament to the Federated Indians of Graton Rancheria’s commitment to giving back to its community, and to its partnership with the library’s mission to support all who wish to discover, learn and share knowledge while we grow as a society,” said Erika Thibault, Interim Director, Sonoma County Library. “This is an important step in a long and mutually beneficial collaboration aimed at serving our community and learning together. We are incredibly grateful to Chairman Sarris and the Tribal Council for this visionary commitment.” About the Federated Indians of Graton Rancheria Graton Rancheria is a federally recognized Indian tribe comprised of Coast Miwok and Southern Pomo Indians. Legislation restoring federal recognition to the Federated Indians of Graton Rancheria was signed into law in December 2000. Tribal lands are located in Rohnert Park, Sonoma County, CA. For more information about FIGR, visit www.gratonrancheria.com. About Sonoma County Library The Sonoma County Library is a countywide system, encompassing all nine cities and the unincorporated areas. A Joint Powers Agreement created in 1975, and revised in 2014, established the library as a separate public agency. Today, the library serves half a million county residents, at 12 regional libraries, two community libraries, three special collections, and a growing array of digital resources. www.Sonomalibrary.org # # # Contact Details Landis Communications Inc. Robin Carr +1 415-971-3991 graton@landispr.com Company Website https://gratonrancheria.com/

August 29, 2022 06:53 PM Eastern Daylight Time

Tiny Homes and Airbnb: Why It Pay$ to Be Unique: An Up-Close Look at One-of-A-Kind Stays on Airbnb

YourUpdateTV

Hosts around the world have been sharing their unique spaces on Airbnb for well over a decade, and guests have fallen for their one-of-a-kind stays, from domes and windmills to lighthouses and trains. Recently, Ellis Nanney, host of a tiny home in Boise, Idaho, conducted a satellite media tour to talk about his experience being the host of a tiny house and the financial benefits of listing a unique space on Airbnb. A video accompanying this announcement is available at: https://youtu.be/7lxB2RasYxU In the past two years alone, from 2019 to 2021, nights booked at unique properties have increased globally by nearly 50 percent. With more guests booking unique stays, Hosts are also earning real income, with unique listings earning nearly $1 billion just in 2021. In fact, globally, earnings by night and by traveler were higher for unique than for non-unique listings in 2021. Through Airbnb Categories, launched this past May, it is also easier for guests to search unique listing types, from Treehouses to Caves, Campers to Barns, and connect with unique homes and Hosts they may have otherwise overlooked. A brand new OMG! Category, which has been clicked on over 2.5 million times since launch, also showcases the zaniest of all unique homes on the platform. The OMG! Category even inspired a first-of-its-size $10,000,000 OMG! Fund, which will award 100 of the craziest listing ideas with $100,000 each, turning over-the-top architectural musings into real-life homes, bookable on Airbnb. Tiny but Mighty: Tiny Homes Most Booked Listing Types in the World While treehouses and barns abound on Airbnb — and are among the top 10 most booked unique listing types in the world, it’s tiny homes that take top spot, proving that a little creativity can go a long way. In 2021, more than 2.5 million nights were booked in tiny homes. Tiny homes come in all shapes, but relatively the same small size. And their Hosts know that there’s nothing tiny about their income: Tiny homes around the world earned their Hosts a total of more than $195 million in 2021 – the top grossing unique space type. Take it from tiny home Host Ellis, who purchased a property in the heart of Idaho and spent the next five years building his own tiny house. He finally listed it on Airbnb in 2019, and the property quickly paid for itself— along with even earning Ellis enough money to put toward his travels and investments too. Treetops at the Top: Most Wishlisted Unique Homes in the World When they are not booking, guests are daydreaming about unique getaways, adding countless inspired stays to their wishlists. In 2021, unique listings were added to almost 20 million wishlists worldwide. Tucked away in a serene and leafy neighborhood in East Point, Georgia, USA sits the most wishlisted unique listing in the world, a beautifully appointed treehouse, with all the rustic trimmings but plenty of modern considerations, from a hot tub to indoor heated spaces, for the most cozy stay. It’s no surprise that Lawrene – a successful actress and sparetime weaver (and lighthouse keeper!) in Florence, Canada – has found accidental success from this treehouse craze. After enjoying her own Airbnb stay in Brooklyn, Lawrene wondered what it would be like to try hosting herself, sharing the off-the-grid space she built for herself ten years earlier, right in her backyard. While she convinced her husband to list the space by assuring him hardly anyone would be interested in staying in their rustic escape, to her husband’s surprise, they have welcomed a steady stream of outdoor enthusiasts and no-trace campers since 2012, who enjoy the peaceful escape – and the homemade waffles Lawrene prepares for breakfast. To find out more about the hosting or booking tiny homes and other unique spaces go to Airbnb.com About Ellis Nanney Ellis Nanney was born and raised in the Pacific Northwest where his love for adventure and freedom was developed from an early age. After graduating from Boise State University, he decided to ditch the career path and live his life in a more entrepreneurial way. Coming hot off of a study abroad semester in Sevilla, Spain, the travel bug and an insatiable desire to explore the world took the reins and set him on an unconventional path for the next decade. His work life was filled with either seasonal or temporary jobs that had him marketing Idaho Potatoes as a self-proclaimed ‘Spud Stud’, promoting the Mexican Caribbean as the ‘Cancun Experience Officer’, hosting a travel show called the Fireball Run, and managing the world’s greatest travel experience, the TukTuk Tournament in Sri Lanka. In between these ‘jobs’ he filled the gaps with international trips that have taken him to nearly 40 countries across 6 continents. Along this journey he was always looking for a way to make this lifestyle sustainable while also providing security for his future. This led him to buy a piece of property and build a tiny house that he could both use as a home base and be a source of passive income to support his adventures. Thanks to the help of Airbnb’s platform and many friends and family members along the way, his unique property has had nothing but success. He’s been an Airbnb Superhost since he began in 2019 and now has much more freedom to choose among life’s opportunities. About Airbnb Airbnb was born in 2007 when two Hosts welcomed three guests to their San Francisco home and has since grown to 4 million Hosts who have welcomed more than 1 billion guest arrivals in almost every country across the globe. Every day, Hosts offer one-of-a-kind stays and unique Experiences that make it possible for guests to experience the world in a more authentic, connected way. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

August 29, 2022 02:30 PM Eastern Daylight Time

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Amesite Announces Partnership with Central Michigan University to Deliver a Complete Upskilling Solution

Amesite Inc.

Contact Details Amesite, Inc. +1 734-876-8141 info@amesite.com Company Website http://www.amesite.io

August 29, 2022 10:00 AM Eastern Daylight Time

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OTC: $PKANF. TSX: $SBBC.V Don't Miss This Interview With Kathy Casey, CEO, Simply Better Brands Corp.

Simply Better Brands

Contact Details Investor Relations ir@simplybetterbrands.com Company Website http://www.simplybetterbrands.com

August 29, 2022 08:54 AM Eastern Daylight Time

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Minuteman Press Franchise in Swindon, England Reopens Doors After Flooding and Fire

Minuteman Press International Inc

Minuteman Press in Swindon, England has reopened its physical location at 19-21 Newport Street (Ground Floor – Newport House). After suffering water damage from flooding in July of 2021 and electrical fire damage in October of 2021, owner James Beckwith and his team continued to operate and serve clients as repairs were being made. James shares, “The community has been fantastic, we officially remained open the whole time taking orders from the website and emails, as well as keeping our phone lines open. We have had nothing but positive comments and folks telling us they are so happy we are back open. Some customers have commented that though they had to go elsewhere for a time, the quality of the print and the quality of the service just didn’t compare to what they received when working with us.” During this critical time and leading to the reopening of their facility, James was grateful to be part of the Minuteman Press franchise family, who stepped in and provided crucial support in many areas. James says, “Mark Jones (UK South Regional VP) and Richard Myers (local field rep) and Duncan Diesel (at MPIHQ) have been invaluable to us. I routinely spoke with Duncan on equipment decisions when ours was being replaced as well as marketing ideas and technical help with Minuteman Press FLEX software and the new website. Richard has been out to see us during the time we had no premises to work up a plan once we were back open and he has been out since opening to assist with production processes and marketing ideas. Mark Jones was always at the end of the phone if we needed advice on anything. He was very key in us making the decision to stay in our current premises when we were investigating moving locations.” Being part of the Minuteman Press system also enabled James to receive vital support from choice vendors like Xerox. James states, “I want to particularly give a shout out to Xerox. They were amazing throughout the entire process. The Xerox kit was always the most expensive shop item and there were lots of negotiations on price to replace the two Versants that were damaged. They ultimately gave us the opportunity to acquire the Xerox Iridesse and offline booklet maker to match the requirements from the two previous Versants while keeping the insurance company happy on cost. Xerox also gave me near free reign of their Uxbridge HQ where I was allowed to run one particular job on their presses every month for six or seven months.” Today, with the repairs finished, new equipment in place and new signage installed, James is excited about the upgrades that have been made to the business. He says, “Our offices and production area have been refurbished, and we can now provide more services than before.” James continues, “We now have totally new kit, and because it is so versatile, we can offer more options than before, with an even faster turnaround. The new Xerox Iridesse is a full production press allowing us more and faster capabilities as well as improved image quality over our previous presses.” He adds, “Even our booklet-making capacity has improved. Whereas before, making a large number of booklets could take several hours, we can now produce up to 3,000 booklets in an hour.” James further explains the benefits of the new equipment installed at Minuteman Press in Swindon: “The Iridesse is absolutely amazing. The image quality is second to none. The job that I would run at Xerox HQ was a monthly magazine run for a local village. 1050 copies, ranging from 20 – 32 pages each month. On our Versants, the job would take 6 – 8 hours. Now the entire job takes us about 2 hours!” We were able to update our Duplo 615 to the 618 and that piece of kit is a dream. Touch screen, easy to configure and very dependable. We replaced our SureColour T5200 with the same model, however now we have the large format scanner which was one area we were sorely lacking. Customers would routinely come in with paper plans looking to get copies or scans and we would have to turn them away, now we can handle the full job for them. We replaced our HP Latex 330 with the Latex 335 that has the Print & Cut feature. We couldn’t be happier with the decision. We are still getting our feet wet with the Print & Cut, but so far we are producing work on all the new kit.” Minuteman Press in Swindon also plans to re-add dye sublimation and add a self-service area for walk-in customers who need a simple print job. James says, “This is really ideal if someone wants a return label printed, for example. We always offered this kind of service for customers, but soon they will be able to do it on a DIY basis.” James concludes, “We are happy to be back in our new and improved facility, and we are excited to continue to welcome back our clients. We are so thankful for them and all of the help we’ve received from our community and MPIHQ, and now we are ready to serve our clients better than ever before.” For more information about Minuteman Press in Swindon, visit https://minuteman.com/uk/locations/england/swindon/ To learn more about #1 rated Minuteman Press franchise opportunities and to see Minuteman Press franchise reviews, visit https://minutemanpressfranchise.co.uk or https://minutemanpressfranchise.com Contact Details Chris Biscuiti +1 631-249-1370 cbiscuiti@mpihq.com Company Website https://minutemanpressfranchise.com

August 26, 2022 05:00 AM Eastern Daylight Time

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